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Biosensors, Volume 11, Issue 5

May 2021 - 37 articles

Cover Story: Detection of mammalian organisms is based on the observation of footprints. This, however, is not the strategy when it comes to microorganisms, since there are no feet to make the footprints. That said, by using molecular printing, it is possible to create 3D “prints” with shape and chemistry to fit each microorganism. These 3D prints indicate selectivity and high sensitivity since the organism used for creating the imprints is efficiently monitored, while other organisms will not be recognized. The imprint can be reused if it is rinsed between the assays. The limit of detection increases linearly by obtaining a baseline noise. The whole-cell-based microbial biosensors are low cost to prepare, along with having portability by miniaturization. The microorganism-based sensors hold important promise in the early diagnosis, with accurate and rapid detection and appropriate control measurements. View this paper.
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Articles (37)

  • Article
  • Open Access
25 Citations
6,882 Views
9 Pages

Highly Sensitive Colorimetric Assay of Cortisol Using Cortisol Antibody and Aptamer Sandwich Assay

  • Yoonjae Kim,
  • Jongmin Yang,
  • Hyeyeon Hur,
  • Seungju Oh and
  • Hyun Ho Lee

20 May 2021

In this study, cortisol, which is a key stress hormone, could be detected sensitively via the colorimetric assay of a polycarbonate (PC) and glass substrate by the sandwich assay of cortisol monoclonal antibody (c-Mab) and cortisol specific binding a...

  • Article
  • Open Access
8 Citations
4,002 Views
10 Pages

20 May 2021

Exosomes are a kind of membrane-bound phospholipid nanovesicle that are secreted extensively in a variety of biological fluids. Accumulating evidence has indicated that exosomes not only communicate with cells, but also perform functional roles in ph...

  • Article
  • Open Access
2 Citations
3,969 Views
13 Pages

19 May 2021

The perfusion culture of primary hepatocytes has been widely adopted to build bioreactors for various applications. As a drug testing platform, a unique vertical-flow bioreactor (VfB) array was found to create the compaction culture of hepatocytes wh...

  • Article
  • Open Access
18 Citations
4,320 Views
20 Pages

19 May 2021

Classification performances for some classes of electrocardiographic (ECG) and electroencephalographic (EEG) signals processed to dimensionality reduction with different degrees are investigated. Results got with various classification methods are gi...

  • Article
  • Open Access
29 Citations
8,501 Views
17 Pages

Thermoplastic Elastomer (TPE)–Poly(Methyl Methacrylate) (PMMA) Hybrid Devices for Active Pumping PDMS-Free Organ-on-a-Chip Systems

  • Mathias Busek,
  • Steffen Nøvik,
  • Aleksandra Aizenshtadt,
  • Mikel Amirola-Martinez,
  • Thomas Combriat,
  • Stefan Grünzner and
  • Stefan Krauss

19 May 2021

Polydimethylsiloxane (PDMS) has been used in microfluidic systems for years, as it can be easily structured and its flexibility makes it easy to integrate actuators including pneumatic pumps. In addition, the good optical properties of the material a...

  • Article
  • Open Access
15 Citations
5,037 Views
11 Pages

A Self-Priming Microfluidic Chip with Cushion Chambers for Easy Digital PCR

  • Gangwei Xu,
  • Huaqing Si,
  • Fengxiang Jing,
  • Peng Sun and
  • Dongping Wu

18 May 2021

A polydimethylsiloxane (PDMS)-based self-priming microfluidic chip with cushion chambers is presented in this study for robust and easy-operation digital polymerase chain reaction (dPCR). The chip has only one inlet and can partition samples autonomo...

  • Article
  • Open Access
14 Citations
4,067 Views
13 Pages

Comparison of Leading Biosensor Technologies to Detect Changes in Human Endothelial Barrier Properties in Response to Pro-Inflammatory TNFα and IL1β in Real-Time

  • James J. W. Hucklesby,
  • Akshata Anchan,
  • Simon J. O'Carroll,
  • Charles P. Unsworth,
  • E. Scott Graham and
  • Catherine E. Angel

18 May 2021

Electric Cell-Substrate Impedance Sensing (ECIS), xCELLigence and cellZscope are commercially available instruments that measure the impedance of cellular monolayers. Despite widespread use of these systems individually, direct comparisons between th...

  • Article
  • Open Access
13 Citations
3,697 Views
13 Pages

A Label and Probe-Free Zika Virus Immunosensor Prussian Blue@carbon Nanotube-Based for Amperometric Detection of the NS2B Protein

  • Bárbara V. M. Silva,
  • Marli T. Cordeiro,
  • Marco A. B. Rodrigues,
  • Ernesto T. A. Marques and
  • Rosa F. Dutra

16 May 2021

Zika virus (ZIKV) is a mosquito-borne infection, predominant in tropical and subtropical regions causing international concern due to the ZIKV disease having been associated with congenital disabilities, especially microcephaly and other congenital a...

  • Communication
  • Open Access
51 Citations
4,901 Views
10 Pages

Electrochemical Fingerprint Biosensor for Natural Indigo Dye Yielding Plants Analysis

  • Boyuan Fan,
  • Qiong Wang,
  • Weihong Wu,
  • Qinwei Zhou,
  • Dongling Li,
  • Zenglai Xu,
  • Li Fu,
  • Jiangwei Zhu,
  • Hassan Karimi-Maleh and
  • Cheng-Te Lin

14 May 2021

Indigo is a plant dye that has been used as an important dye by various ancient civilizations throughout history. Today, due to environmental and health concerns, plant indigo is re-entering the market. Strobilanthes cusia (Nees) Kuntze is the m...

  • Article
  • Open Access
12 Citations
7,855 Views
11 Pages

Cas12a and Lateral Flow Strip-Based Test for Rapid and Ultrasensitive Detection of Spinal Muscular Atrophy

  • Chunhua Zhang,
  • Zhuo Li,
  • Miaomiao Chen,
  • Zhiqing Hu,
  • Lingqian Wu,
  • Miaojin Zhou and
  • Desheng Liang

14 May 2021

Spinal muscular atrophy (SMA) is characterized by severe lethality and irreversible progression. Early diagnosis of SMA is of more practical significance with the emergence of effective therapy. However, existing techniques to identify SMA patients r...

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Biosensors - ISSN 2079-6374