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Biosensors, Volume 11, Issue 6

June 2021 - 38 articles

Cover Story: Multi-parameter SPR was used to develop a reliable and label-free detection method for HIV-1 p24 capsid protein. The study aimed at the assessment of a biosensing assay for the early detection of the human immunodeficiency virus (HIV). Remarkably, both physical and chemical immobilization of mouse monoclonal antibodies against HIV-1 p24 on the SPR gold detecting surface have been characterized for the first time. An equilibrium dissociation constant KD of 5.30 × 10−9 M was computed for the assay on the chemically modified surface. The system was also characterized in terms of sensitivity and selectivity, reaching a limit of detection of 4.1 ± 0.5 nM and an unprecedented selectivity ratio of 0.02. View this paper.
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Articles (38)

  • Article
  • Open Access
31 Citations
4,019 Views
10 Pages

21 June 2021

In this paper, a bimetallic sensor based on graphene-hexagonal boron nitride (hBN) heterostructure is theoretically studied. The sensitivity of the sensor can be improved by enhancing the Goos–Hänchen (GH) shift in the infrared band. The theoretical...

  • Article
  • Open Access
13 Citations
4,557 Views
13 Pages

Electrochemical Immunosensing of ST2: A Checkpoint Target in Cancer Diseases

  • Rebeca M. Torrente-Rodríguez,
  • Cristina Muñoz-San Martín,
  • Maria Gamella,
  • María Pedrero,
  • Neus Martínez-Bosch,
  • Pilar Navarro,
  • Pablo García de Frutos,
  • José M. Pingarrón and
  • Susana Campuzano

21 June 2021

A magnetic beads (MB)-involved amperometric immunosensor for the determination of ST2, a member of the IL1 receptor family, is reported in this work. The method utilizes a sandwich immunoassay and disposable screen-printed carbon electrodes (SPCEs)....

  • Article
  • Open Access
15 Citations
4,359 Views
12 Pages

Polystyrene Microsphere-Based Immunochromatographic Assay for Detection of Aflatoxin B1 in Maize

  • Jin Wang,
  • Xiangmei Li,
  • Xing Shen,
  • Ang Zhang,
  • Jinxiu Liu and
  • Hongtao Lei

20 June 2021

Aflatoxin B1 (AFB1), a mycotoxin, is hepatotoxic, carcinogenic, and nephrotoxic in humans and animals, and contaminate a wide range of maize. In this study, an immunochromatographic assay (ICA) based on polystyrene microspheres (PMs) was developed fo...

  • Article
  • Open Access
9 Citations
4,669 Views
13 Pages

Cranberry Proanthocyanidins-PANI Nanocomposite for the Detection of Bacteria Associated with Urinary Tract Infections

  • Hilary Urena-Saborio,
  • Anu Prathap M. Udayan,
  • Emilia Alfaro-Viquez,
  • Sergio Madrigal-Carballo,
  • Jess D. Reed and
  • Sundaram Gunasekaran

19 June 2021

Consumption of cranberries is associated with the putative effects of preventing urinary tract infections (UTIs). Cranberry proanthocyanidins (PAC) contain unusual double A-type linkages, which are associated with strong interactions with surface vir...

  • Article
  • Open Access
33 Citations
6,217 Views
13 Pages

Eye-Movement-Controlled Wheelchair Based on Flexible Hydrogel Biosensor and WT-SVM

  • Xiaoming Wang,
  • Yineng Xiao,
  • Fangming Deng,
  • Yugen Chen and
  • Hailiang Zhang

16 June 2021

To assist patients with restricted mobility to control wheelchair freely, this paper presents an eye-movement-controlled wheelchair prototype based on a flexible hydrogel biosensor and Wavelet Transform-Support Vector Machine (WT-SVM) algorithm. Cons...

  • Article
  • Open Access
3 Citations
5,444 Views
16 Pages

Development of a Diagnostic Biosensor Method of Hypersensitivity Pneumonitis towards a Point-of-Care Biosensor

  • Tatiana Fiordelisio,
  • Ivette Buendia-Roldan,
  • Mathieu Hautefeuille,
  • Diana Del-Rio,
  • Diana G. Ríos-López,
  • Diego Zamarrón-Hernández,
  • Samuel Amat-Shapiro,
  • Andrea Campa-Higareda,
  • Edgar Jiménez-Díaz and
  • Erika González-Villa
  • + 7 authors

15 June 2021

In spite of a current increasing trend in the development of miniaturized, standalone point-of-care (PoC) biosensing platforms in the literature, the actual implementation of such systems in the field is far from being a reality although deeply neede...

  • Review
  • Open Access
45 Citations
7,364 Views
33 Pages

Trends in the Design of Intensity-Based Optical Fiber Biosensors (2010–2020)

  • Nerea De Acha,
  • Abián B. Socorro-Leránoz,
  • César Elosúa and
  • Ignacio R. Matías

15 June 2021

There exists an increasing interest in monitoring low concentrations of biochemical species, as they allow the early-stage detection of illnesses or the monitoring of the environment quality. Thus, both companies and research groups are focused on th...

  • Communication
  • Open Access
18 Citations
4,662 Views
9 Pages

Study on a Plasmonic Tilted Fiber Grating-Based Biosensor for Calmodulin Detection

  • Xiaoyong Chen,
  • Jie Jiang,
  • Nan Zhang,
  • Wenwei Lin,
  • Pin Xu and
  • Jinghua Sun

14 June 2021

Tilted fiber Bragg grating, which has the advantages of both fiber Bragg grating and long-period fiber grating, has been widely studied for sensing in many fields, especially in the field of biochemistry. Calmodulin, which has a wide distribution in...

  • Article
  • Open Access
9 Citations
3,578 Views
19 Pages

Stochastic Time Response and Ultimate Noise Performance of Adsorption-Based Microfluidic Biosensors

  • Ivana Jokić,
  • Zoran Djurić,
  • Katarina Radulović,
  • Miloš Frantlović,
  • Gradimir V. Milovanović and
  • Predrag M. Krstajić

12 June 2021

In order to improve the interpretation of measurement results and to achieve the optimal performance of microfluidic biosensors, advanced mathematical models of their time response and noise are needed. The random nature of adsorption–desorption and...

  • Article
  • Open Access
36 Citations
8,857 Views
12 Pages

10 June 2021

In this study, we developed the portable chemiluminescence (CL)-based lateral flow assay (LFA) platform for the detection of cortisol in human serum. Cortisol is well-known as a stress hormone due to its high relevancy for human mental and physical h...

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Biosensors - ISSN 2079-6374