Special Issue "Optical Sensors for Bio-Sensing, Imaging and Theranostics Applications"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editors

Prof. Dr. Junle Qu
E-Mail Website
Guest Editor
Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China
Interests: fluorescence lifetime imaging microscopy; high spatial resolution retinal imaging; biomedical photonics; biomedical optical imaging; nanobiophotonics
Prof. Dr. Zhigang Yang
E-Mail Website
Guest Editor
College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China
Interests: optical probes; super-resolution imaging; FLIM; NIR imaging; bioimaging
Special Issues and Collections in MDPI journals
Prof. Dr. Jong Seung Kim
grade E-Mail Website
Guest Editor
Department of Chemistry, Korea University, Seoul 02841, Korea
Interests: supramolecular chemistry; drug delivery system; fluorescent probes; fluorescent imaging; therapeutics
Special Issues and Collections in MDPI journals
Prof. Dr. Anderson S. L. Gomes
E-Mail Website
Guest Editor
Physics Department, Universidade Federal of Pernambuco, Recife, PE 50670-901, Brazil
Interests: nonlinear optics; nanophotonics; biophotonics optical coherence tomography

Special Issue Information

Dear Colleagues,

The "Optical Sensors for Bio-Sensing, Imaging, and Theranostics Applications" section covers all aspects of research on the development of various probes or sensors using light or lasers for biomedical sensing, imaging, diagnosis, and therapeutics. The signal can be detected using a single optical modality or multi-modalities, such as single-/two-/multi-photon fluorescence imaging, super-resolution optical imaging, fluorescence lifetime imaging microscopy(FLIM), optical coherence tomography (OCT), photothermal imaging, photoacoustic imaging, etc. The optical sensors or probes can be developed and used in such imaging modalities but not limited to the methods mentioned above. The key issue is to highlight the advanced optical probes or biosensors used in bio-sensing, imaging for acquiring biological information, and disease diagnosis and therapy, especially for clinic applications. In this regard, it is expected that many articles focusing on the biological applications will center on precisely structural or functional imaging at the levels of cell, organelle, or animals using different modes. This Section provides a vehicle for the publication of articles that will have a significant impact on the general bio-sensing and bio-imaging area and will also attract interest in the wider communities referred to above.

Prof. Dr. Junle Qu
Prof. Dr. Zhigang Yang
Prof. Dr. Jong Seung Kim
Prof. Dr. Anderson S. L. Gomes
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

Article
The Spectroscopic Properties and Microscopic Imaging of Thulium-Doped Upconversion Nanoparticles Excited at Different NIR-II Light
Biosensors 2021, 11(5), 148; https://doi.org/10.3390/bios11050148 - 10 May 2021
Viewed by 453
Abstract
Lanthanide-doped upconversion nanoparticles (UCNPs) are promising bioimaging nanoprobes due to their excellent photostability. As one of the most commonly used lanthanide activators, Tm3+ ions have perfect ladder-type electron configuration and can be directly excited by bio-friendly near-infrared-II (NIR-II) wavelengths. Here, the emission [...] Read more.
Lanthanide-doped upconversion nanoparticles (UCNPs) are promising bioimaging nanoprobes due to their excellent photostability. As one of the most commonly used lanthanide activators, Tm3+ ions have perfect ladder-type electron configuration and can be directly excited by bio-friendly near-infrared-II (NIR-II) wavelengths. Here, the emission characteristics of Tm3+-doped nanoparticles under laser excitations of different near-infrared-II wavelengths were systematically investigated. The 1064 nm, 1150 nm, and 1208 nm lasers are proposed to be three excitation strategies with different response spectra of Tm3+ ions. In particular, we found that 1150 nm laser excitation enables intense three-photon 475 nm emission, which is nearly 100 times stronger than that excited by 1064 nm excitation. We further optimized the luminescence brightness after investigating the luminescence quenching mechanism of bare NaYF4: Tm (1.75%) core. After growing an inert shell, a ten-fold increase of emission intensity was achieved. Combining the advantages of NIR-II wavelength and the higher-order nonlinear excitation, a promising facile excitation strategy was developed for the application of thulium-doped upconversion nanoparticles in nanoparticles imaging and cancer cell microscopic imaging. Full article
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