2025 December - 45 articles
This study aimed to identify the optimal printing orientation (X, Y, or Z axis) and positioning of a mandibular molar presenting an isthmus using PolyJet™ technology. The influence of these parameters on dimensional accuracy and on the behavior...
Due to the limitations of SRP, new methods are being sought to support non-surgical periodontal therapy. One of them is the use of antiseptics such as low-concentration sodium hypochlorite gel buffered with amino acids (NaOCl/AA). The aim of the stud...
Acellular dermal matrices (ADMs) are widely used in soft-tissue reconstruction, yet the optimal timing for split-thickness skin grafting (STSG) remains unsettled. We conducted a single-center retrospective cohort study (January 2023–August 2025...
The growing use of 3D-printed dental restorations has created a need to understand how the mechanical behaviour of definitive 3D-printed resin composites compares with milled counterparts. This study compared the mechanical properties of 3D-printed a...
Introduction: The split crest (SC) is a technique for horizontal ridge augmentation that enables simultaneous implant placement. While the use of bone grafts within the osteotomy gap is well-documented, the efficacy of dentin as a graft material in S...
Collagen-based biomaterials are widely used, but their relatively rapid biodegradation can limit functional duration. Such collagen constructs are widely used as barrier membranes in guided tissue and bone regeneration, where controlled degradation i...
Carbon dots have emerged as promising nanocarriers for drug delivery due to their unique physicochemical properties and biocompatibilities. Here, the potential of leaf-derived carbon dots (named as SBLCD), derived from Seabuckthorn (Hippophae rhamnoi...
In the original publication [...]
Calcium phosphate cements (CPCs) and biomaterials, such as mesoporous bioactive glass (MBG), are critical for bone tissue engineering. This study aimed to 3D-print CPC scaffolds modified with MBG to enhance their osteogenic potential and regenerative...
Denture base resins are susceptible to microbial colonization, and current antibacterial additives often lose effectiveness and may weaken material properties. This study evaluated whether immersion in a quaternary ammonium methacryloxy silane (QAMS)...
Magnetosomes (MTS), membrane-enclosed magnetic nanoparticles naturally biomineralized by magnetotactic bacteria, are promising materials for tumor hyperthermia owing to their good biocompatibility and heating efficiency. However, their application is...
The development of advanced biomaterials for corneal applications requires robust translational platforms that faithfully replicate human characteristics. Porcine corneas are increasingly recognized for ophthalmic research. Their unique combination o...
The primary reason of dental restoration failure is the recurrence of caries, driving research to incorporate quaternary ammonium salts (QASs) into resin-based composites (RBCs). Given the prolonged contact of these materials with oral tissue, this i...
Bone cements based on polymethyl methacrylate (PMMA) remain the clinical standard for joint replacement and vertebral augmentation but suffer from several major challenges. These include excessive stiffness compared with cancellous bone, lack of reso...
Purpose: This in vitro study ascertained the impact of three distinct alumina particle sizes on the shear bond strength (SBS) between two distinct provisional crowns (milled and 3D-printed) and stainless-steel orthodontic brackets following artificia...
The development of polymer-based systems is central to the design of next-generation drug delivery carriers, as polymers enable versatile tuning of physicochemical properties and responsiveness. In this work, we introduce a 3D printing-based strategy...
Binder jet 3D printing of calcium sulfate-based materials combined with phase transformation offers a versatile route for fabricating customized bone grafts; however, controlling the transformation process remains a key challenge. This study investig...
Severe traumatic brain injury includes neurovascular unit (NVU) damage that is linked to the later development of neurodegenerative diseases. Cell-type-specific contributions and crosstalk between cells of the neurovascular unit following brain injur...
Minimally invasive treatment is increasingly successful in managing carious lesions in primary teeth, owing to the regenerative capacity of the dental pulp and the possibility to influence the pulp–dentin complex. Chemo-mechanical caries excava...
Vital pulp therapy (VPT) seeks to preserve pulp vitality by using biocompatible with regenerative potential. This study tested the hypothesis that an injectable gelatin methacryloyl (GelMA) hydrogel containing piezoelectric barium titanate promotes o...
Tissue engineering approaches for cartilage tissue regeneration are expanding to include the complex features of the tissue, such as the biological and mechanical gradients. Many of these approaches are, however, based on the use of multiple biomater...
The overactivation of endosomal Toll-like receptor (TLR) in macrophages plays an important role in the pathogenesis of acute lung injury (ALI). There is currently still a lack of nano-formulated and macrophage-targeted endosomal TLR inhibitors that h...
Background/Objectives: This study aimed to evaluate the mechanical properties, particularly the fracture load, modulus of elasticity, and fracture patterns, of four-unit posterior tooth-supported fixed dental prostheses (FDPs) fabricated from various...
Tissue responses to zirconia-coated implants treated with molecular precursor method were evaluated. The zirconia film was characterized using scanning electron microscopy (SEM), atomic force microscopy (AFM), energy dispersive X-ray spectroscopy (ED...
Implantable scaffolds are increasingly recognized as transformative tools in regenerative medicine, offering the potential to prevent or mitigate tissue degeneration. Osteoarthritis is a widespread degenerative joint disease that often progresses fro...
The objective of this study was to investigate the effect of surface disinfectant solutions against COVID-19 on the surface roughness, gloss, and color of removable denture materials. Fifty rectangular metallic specimens made of Co-Cr alloy and fifty...
Calcium silicate-based cement is commonly used for bone repair and regeneration. Current research focuses on developing innovative antibacterial materials with radiopacity, which is essential for ensuring successful clinical outcomes in procedures li...
This study aimed to evaluate the effect of popular beverages, coffee, matcha, and protein isolate, on the microhardness and color stability of feldspar glass ceramic (VB) and nano-ceramic hybrid composite (GD) CAD/CAM materials. Three hundred specime...
The literature consistently identifies Zeolitic Imidazolate Framework-8 (ZIF-8) as an excellent material for on-demand drug delivery. Its appeal results from its superior loading capacity, inherent stability within physiological environments, and the...
In clinical practice, the selection of dental material is a crucial factor for the final success of the treatment, regarding mechanical properties and biocompatibility. Our study aimed to evaluate the cytotoxicity of a PMMA dental resin used for dent...
This study addresses the challenges of osteochondral tissue engineering by developing a hybrid scaffold with intercalated layers of poly(ε-caprolactone) (PCL) in combination with different concentrations of nanosized synthetic smectic clay (L...
Natural or synthetic scaffolds are essential for developing three-dimensional (3D) cell culture models, as they provide structural stability and accurately replicate the cellular microenvironment. When integrated into optimized setups, scaffold-suppo...
Commercially pure (CP) titanium is widely used for long-term biomedical implants due to its high biocompatibility and corrosion resistance. However, its relatively low strength limits its use in highly loaded applications. Ultrafine-grained (UFG) tit...
Guided bone regeneration (GBR) plays a key role in alveolar ridge augmentation and implant therapy, but the biological mechanisms governing its outcomes are not fully understood. Preclinical animal models provide critical insights that cannot be obta...
Background: Articular cartilage has limited self-repair capacity. While thermoresponsive poly N-isopropyl acrylamide (pNIPAAm)-based Cell Sheet Engineering (CSE) is a promising scaffold-free strategy, its inherent material properties pose limitations...
Three-dimensional (3D) bioprinting has become a widely exploited tissue engineering technique for producing functional constructs that can mimic and replace native tissues. To this end, different printing strategies can be adopted, including inkjet-b...
Novel pure Zn and Zn-3Ag-xFe (x = 0, 1, 3, 5) (wt.%) nanocrystalline powders were synthesized for potential use as implants and stent materials by the mechanical alloying (MA) technique. The morphological and structural alterations of the powders mil...
The high incidence of cardiovascular disease and the early failure of bioprosthetic valves due to calcification have driven the development of anti-calcification technologies. As a new storage technology, drying treatment is expected to delay the cal...
Cancer poses a considerable challenge to global public health and stands as the second leading cause of mortality worldwide. Chemotherapy provides limited benefits for advanced-stage cancer, mainly due to high systemic toxicity and drug resistance. O...
Purpose: The present study evaluates the cytocompatibility of chitosan (CS)-modified glass ionomer cement (GIC) diluents for a Balb/c 3T3 fibroblast cell line. Methods: Three different commercially available hand-mix GIC materials were used in this e...
Biomolecules have gained attention in recent years for their potential to enhance regenerative periodontal therapy. This study compared hyaluronic acid (HA) and enamel matrix derivative (EMD), each combined with a xenogeneic graft, in adults with per...
Orbital wall fractures are a common consequence of trauma-related craniofacial injuries. Multistage treatment and poor functional and aesthetic results render the reconstruction of an orbit extremely challenging. Advances in surgical technologies, im...
The periodontal ligament (PDL) is essential for the physiological mobility and load distribution of natural teeth, yet its simulation in mechanical testing remains inconsistent and insufficiently standardized. The absence of a resilient suspension sy...
This study compared widely used nonabsorbable and monofilament suture materials tied with three different configurations and two different suture techniques. Three suture materials (polytetrafluoroethylene, polypropylene, and nylon) were tied with ei...
Objective: May–Thurner syndrome typically refers to symptoms and signs arising from the compression of the left common iliac vein by the right common iliac artery. However, such clinical manifestations can occur in the setting of compression of...
