Three-Dimensional-Printable Biomaterials for Bone Regeneration

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Bone Biomaterials".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 1792

Special Issue Editor


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Guest Editor
Department of Metallic Materials Science and Physical Metallurgy, Faculty of Materials Science and Engineering, National University of Science and Technology Politehnica Bucharest, Bucharest, Romania
Interests: biomaterials; biomedical applications; bone regeneration; bone substitutes; biocompatible material synthesis; composites; nanomaterials; bioceramics; biogenic calcium phosphates; hydroxyapatite; additive manufacturing; 3D printing; printable antimicrobial biomaterials; biomedical applications of additive manufacturing; material characterization and testing

Special Issue Information

Dear Colleagues,

The development of an efficient regenerative approach for the restoration of diseased, traumatized, or damaged parts of the natural bone to their initial anatomical, physiological, and functional state has constituted, for at least the last decade, huge potential in the biomedical field. In the quest of developing innovative and modern biomaterials for mature bone regeneration applications, additive manufacturing and 3D printing techniques are desired to address compelling and stringent issues related to the final customization of bone-like products. The modification and improvement of commonly used materials or raw resources for 3D printers leads to a continuous and necessary rush for new developments and possibilities in the area of rapid fabrication of complex products with augmented features.

Through this Special Issue, distinguished researchers are emboldened to publish and promote original and innovative scientific studies carried out on dedicated biomaterials with printable features for bone regeneration using the latest technological advancements in the 3D printing field.

It is my pleasure to invite all of you to submit manuscripts for inclusion in the Special Issue entitled “Three-Dimensional-Printable Biomaterials for Bone Regeneration”. Research articles and review papers are welcomed.

Dr. Aura-Catalina Mocanu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • biomaterials
  • printable features
  • 3D printing
  • bone regeneration
  • bone substitutes
  • customized products

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Published Papers (1 paper)

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Review

36 pages, 3511 KiB  
Review
Three-Dimensional Bioprinting for Intervertebral Disc Regeneration
by Md Amit Hasan Tanvir, Md Abdul Khaleque, Junhee Lee, Jong-Beom Park, Ga-Hyun Kim, Hwan-Hee Lee and Young-Yul Kim
J. Funct. Biomater. 2025, 16(3), 105; https://doi.org/10.3390/jfb16030105 - 14 Mar 2025
Viewed by 1039
Abstract
The rising demand for organ transplants and the need for precise tissue models have positioned the in vitro biomanufacturing of tissues and organs as a pivotal area in regenerative treatment. Considerable development has been achieved in growing tissue-engineered intervertebral disc (IVD) scaffolds, designed [...] Read more.
The rising demand for organ transplants and the need for precise tissue models have positioned the in vitro biomanufacturing of tissues and organs as a pivotal area in regenerative treatment. Considerable development has been achieved in growing tissue-engineered intervertebral disc (IVD) scaffolds, designed to meet stringent mechanical and biological compatibility criteria. Among the cutting-edge approaches, 3D bioprinting stands out due to its unparalleled capacity to organize biomaterials, bioactive molecules, and living cells with high precision. Despite these advancements, polymer-based scaffolds still encounter limitations in replicating the extracellular matrix (ECM)-like environment, which is fundamental for optimal cellular activities. To overcome these challenges, integrating polymers with hydrogels has been recommended as a promising solution. This combination enables the advancement of porous scaffolds that nurture cell adhesion, proliferation, as well as differentiation. Additionally, bioinks derived from the decellularized extracellular matrix (dECM) have exhibited potential in replicating biologically relevant microenvironments, enhancing cell viability, differentiation, and motility. Hydrogels, whether derived from natural sources involving collagen and alginate or synthesized chemically, are highly valued for their ECM-like properties and superior biocompatibility. This review will explore recent advancements in techniques and technologies for IVD regeneration. Emphasis will be placed on identifying research gaps and proposing strategies to bridge them, with the goal of accelerating the translation of IVDs into clinical applications. Full article
(This article belongs to the Special Issue Three-Dimensional-Printable Biomaterials for Bone Regeneration)
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