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Journal of Clinical Medicine, Volume 9, Issue 2

February 2020 - 324 articles

Cover Story: Due to the great therapeutic interest involving the clinical translation of MSCs, they are being widely studied to determine their mechanism of action (MoA) in order to evaluate their efficacy, feasibility and safety in humans for the treatment of numerous pathologies. The therapeutic effects of MSCs compromise different mechanisms such as their capacity of migration and functional integration into diseased host tissue, their paracrine support and their impact on the regulation of both the innate and the acquired immune system. View this paper.
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Articles (324)

  • Article
  • Open Access
10 Citations
3,509 Views
11 Pages

Aortic Valve Calcium Associates with All-Cause Mortality Independent of Coronary Artery Calcium and Inflammation in Patients with End-Stage Renal Disease

  • Lu Dai,
  • Oscar Plunde,
  • Abdul Rashid Qureshi,
  • Bengt Lindholm,
  • Torkel B. Brismar,
  • Leon J. Schurgers,
  • Magnus Söderberg,
  • Jonaz Ripsweden,
  • Magnus Bäck and
  • Peter Stenvinkel

24 February 2020

Background: Aortic valve calcium (AVC) and coronary artery calcium (CAC) are common complications in end-stage renal disease (ESRD). We investigated the prognostic significance of overlapping presence of AVC and CAC, and whether AVC was associated wi...

  • Article
  • Open Access
20 Citations
4,819 Views
14 Pages

Risk Factors for Postural and Functional Balance Impairment in Patients with Chronic Obstructive Pulmonary Disease

  • Jaekwan K. Park,
  • Nicolaas E. P. Deutz,
  • Clayton L. Cruthirds,
  • Sarah K. Kirschner,
  • Hangue Park,
  • Michael L. Madigan and
  • Mariëlle P. K. J. Engelen

24 February 2020

Reduced balance function has been observed during balance challenging conditions in the chronic obstructive pulmonary disease (COPD) population and is associated with an increased risk of falls. This study aimed to examine postural balance during qui...

  • Article
  • Open Access
17 Citations
3,988 Views
12 Pages

A Mortality Prediction Rule for Hematology Patients with Invasive Aspergillosis Based on Serum Galactomannan Kinetics

  • Toine Mercier,
  • Joachim Wera,
  • Louis Y. A. Chai,
  • Katrien Lagrou and
  • Johan Maertens

24 February 2020

In invasive aspergillosis (IA), an early and adequate assessment of the response to the initial antifungal therapy remains problematic. We retrospectively analyzed 206 hematology patients with proven or probable IA, and collected serial serum galacto...

  • Article
  • Open Access
59 Citations
8,321 Views
11 Pages

Correlations between Sleep Bruxism and Temporomandibular Disorders

  • Brigitte Ohlmann,
  • Moritz Waldecker,
  • Michael Leckel,
  • Wolfgang Bömicke,
  • Rouven Behnisch,
  • Peter Rammelsberg and
  • Marc Schmitter

24 February 2020

The aim of this study was to identify correlations between sleep bruxism (SB) and temporomandibular disorders (TMD) as diagnosed by means of the research diagnostic criteria for temporomandibular disorders (RDC/TMD). Sleep bruxism was diagnosed on th...

  • Article
  • Open Access
10 Citations
4,297 Views
8 Pages

Microinvasive Fungal Rhinosinusitis: Proposal of a New Subtype in the Classification

  • Min Young Seo,
  • Hyeri Seok,
  • Seung Hoon Lee,
  • Ji Eun Choi,
  • Sang Duk Hong,
  • Seung-Kyu Chung,
  • Kyong Ran Peck and
  • Hyo Yeol Kim

24 February 2020

Background: Fungal rhinosinusitis (FRS) with mucosal invasion is not classified by the current criteria, and clinical reports on the topic are limited. The aim of this study was to present our 25-year experience on fungal balls with mucosal invasion...

  • Article
  • Open Access
137 Citations
24,463 Views
9 Pages

Assessing the Impact of Reduced Travel on Exportation Dynamics of Novel Coronavirus Infection (COVID-19)

  • Asami Anzai,
  • Tetsuro Kobayashi,
  • Natalie M. Linton,
  • Ryo Kinoshita,
  • Katsuma Hayashi,
  • Ayako Suzuki,
  • Yichi Yang,
  • Sung-mok Jung,
  • Takeshi Miyama and
  • Andrei R. Akhmetzhanov
  • + 1 author

24 February 2020

The impact of the drastic reduction in travel volume within mainland China in January and February 2020 was quantified with respect to reports of novel coronavirus (COVID-19) infections outside China. Data on confirmed cases diagnosed outside China w...

  • Review
  • Open Access
16 Citations
6,709 Views
16 Pages

Instruments of Choice for Assessment and Monitoring Diabetic Foot: A Systematic Review

  • Raúl Fernández-Torres,
  • María Ruiz-Muñoz,
  • Alberto J. Pérez-Panero,
  • Jerónimo García-Romero and
  • Manuel Gónzalez-Sánchez

24 February 2020

Diabetic foot is the most frequent disorder among the chronic complications of diabetes, happening in 25% of patients. Objective clinical outcome measures are tests or clinical instruments that provide objective values for result measurement. The aim...

  • Article
  • Open Access
39 Citations
8,417 Views
11 Pages

First Multi-Center All-Comers Study for the Aquablation Procedure

  • Thorsten Bach,
  • Peter Gilling,
  • Albert El Hajj,
  • Paul Anderson and
  • Neil Barber

24 February 2020

Waterjet-based prostate resection (Aquablation procedure) is an increasingly recognized treatment for symptomatic benign prostatic hyperplasia (BPH). We confirmed the safety and effectiveness of the Aquablation procedure in the commercial setting in...

  • Article
  • Open Access
8 Citations
3,786 Views
12 Pages

A Multiplex Test Assessing MiR663ame and VIMme in Urine Accurately Discriminates Bladder Cancer from Inflammatory Conditions

  • Sara Monteiro-Reis,
  • Ana Blanca,
  • Joana Tedim-Moreira,
  • Isa Carneiro,
  • Diana Montezuma,
  • Paula Monteiro,
  • Jorge Oliveira,
  • Luís Antunes,
  • Rui Henrique and
  • António Lopez-Beltran
  • + 1 author

24 February 2020

Bladder cancer (BlCa) is a common malignancy with significant morbidity and mortality. Current diagnostic methods are invasive and costly, showing the need for newer biomarkers. Although several epigenetic-based biomarkers have been proposed, their a...

  • Article
  • Open Access
34 Citations
6,906 Views
15 Pages

Fractional Flow Reserve Derived from Coronary Computed Tomography Angiography Safely Defers Invasive Coronary Angiography in Patients with Stable Coronary Artery Disease

  • Mark Rabbat,
  • Jonathon Leipsic,
  • Jeroen Bax,
  • Brian Kauh,
  • Rina Verma,
  • Demetrios Doukas,
  • Sorcha Allen,
  • Gianluca Pontone,
  • David Wilber and
  • Verghese Mathew
  • + 2 authors

24 February 2020

Objectives: In the United States, the real-world feasibility and outcome of using fractional flow reserve from coronary computed tomography angiography (FFRCT) is unknown. We sought to determine whether a strategy that combined coronary computed tomo...

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J. Clin. Med. - ISSN 2077-0383