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Journal of Clinical Medicine, Volume 13, Issue 24

2024 December-2 - 374 articles

Cover Story: Excessive alcohol consumption is amongst the leading causes of hospitalisation in high-income countries and contributes to over 200 medical conditions. This study aimed to determine the prevalence and characteristics of alcohol use disorder (AUD), describe the distribution of AUD in ICD-10 discharge diagnosis groups, and ascertain any relationship between them in secondary care. This study highlights the high prevalence of AUD among hospitalised patients, with one in six admitted patients being diagnosed with AUD using the AUDIT-C tool. Patients with alcohol dependence were predominantly from the most deprived areas and exhibited a higher prevalence of co-existing mental health disorders. In addition, key factors such as age, sex, emergency admissions, and social determinants were linked to higher odds of AUD, suggesting targeted screening for at-risk groups. View this paper
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Articles (374)

  • Article
  • Open Access
3,412 Views
10 Pages

23 December 2024

Background/Objectives: Ethnocultural differences between Jewish and Arab communities in Northern Israel may contribute to disparities in type 2 diabetes prevalence. Widespread screening strategies, including hospital-based initiatives, are crucial fo...

(This article belongs to the Special Issue Personalized Medicine for the Management of Non-Communicable Disease (NCDs))
  • Article
  • Open Access
1 Citations
2,453 Views
16 Pages

Exercise-Induced Oxygen Desaturation and Outcomes After Nintedanib Therapy for Fibrosing Interstitial Lung Disease in Patients Without Dyspnea

  • Masaki Okamoto,
  • Toyoshi Yanagihara,
  • Kiminori Fujimoto,
  • Tomonori Chikasue,
  • Kazuhiro Tabata,
  • Yoshiaki Zaizen,
  • Masaki Tominaga,
  • Akiko Sumi,
  • Yuuya Nishii and
  • Tomoaki Hoshino
  • + 4 authors

23 December 2024

Background: The degree of exercise-induced oxygen desaturation and outcomes following antifibrotic drug therapy in asymptomatic patients with fibrosing interstitial lung disease (FILD) remain unclear. Methods: We compared clinical data, incidence of...

(This article belongs to the Special Issue Updates on Interstitial Lung Disease)
  • Article
  • Open Access
12 Citations
2,714 Views
16 Pages

ChatGPT’s Performance in Spinal Metastasis Cases—Can We Discuss Our Complex Cases with ChatGPT?

  • Stephan Heisinger,
  • Stephan N. Salzmann,
  • Wolfgang Senker,
  • Stefan Aspalter,
  • Johannes Oberndorfer,
  • Michael P. Matzner,
  • Martin N. Stienen,
  • Stefan Motov,
  • Dominikus Huber and
  • Josef Georg Grohs

23 December 2024

Background: The integration of artificial intelligence (AI), particularly large language models (LLMs) like ChatGPT-4, is transforming healthcare. ChatGPT’s potential to assist in decision-making for complex cases, such as spinal metastasis tre...

(This article belongs to the Special Issue Advances in Surgical Management of Orthopedics—Artificial Intelligence (AI) Applications and Robotic Surgery Techniques)
  • Article
  • Open Access
9 Citations
5,024 Views
14 Pages

Enhancing Surgical Wound Monitoring: A Paired Cohort Study Evaluating a New AI-Based Application for Automatic Detection of Potential Infections

  • Andrea Craus-Miguel,
  • Marc Munar,
  • Gabriel Moyà-Alcover,
  • Ana María Contreras-Nogales,
  • Manuel González-Hidalgo and
  • Juan José Segura-Sampedro

23 December 2024

Background/Objectives: This study assessed the feasibility and security of remote surgical wound monitoring using the RedScar© smartphone app, which employs automated diagnosis for early visual detection of infections without direct healthcare p...

(This article belongs to the Topic AI in Medical Imaging and Image Processing)
  • Article
  • Open Access
1 Citations
4,341 Views
15 Pages

Pregnancy Outcomes in Non-Criteria Obstetric Antiphospholipid Syndrome: Analysis of a Cohort of 91 Patients

  • Sara Beça,
  • Núria Baños,
  • Maria Borrell,
  • Estíbaliz Ruiz-Ortiz,
  • Albert Pérez-Isidro,
  • Ricard Cervera,
  • Joan Carles Reverter,
  • Dolores Tàssies and
  • Gerard Espinosa

23 December 2024

Background: The clinical and laboratory features of patients with non-criteria obstetric antiphospholipid syndrome (NC-OAPS), as well as their pregnancy outcomes and ideal treatment are not clearly determined. The aim of this study is to describe the...

(This article belongs to the Special Issue Antiphospholipid Syndrome: Clinical Advances in Diagnosis and Management)
  • Systematic Review
  • Open Access
22 Citations
5,477 Views
11 Pages

Digital Twins Use in Plastic Surgery: A Systematic Review

  • Ishith Seth,
  • Bryan Lim,
  • Phil Y. J. Lu,
  • Yi Xie,
  • Roberto Cuomo,
  • Sally Kiu-Huen Ng,
  • Warren M. Rozen and
  • Foti Sofiadellis

23 December 2024

Background/Objectives: Digital twin technology, initially developed for engineering and manufacturing, has entered healthcare. In plastic surgery, digital twins (DTs) have the potential to enhance surgical precision, personalise treatment plans, and...

(This article belongs to the Special Issue Clinical Advances in Reconstructive Surgery: Innovations and Outcomes for Improved Patient Care)
  • Article
  • Open Access
2 Citations
1,952 Views
11 Pages

Rates of School Absences in Pediatric Scoliosis Patients and Work Absences in Their Parents/Caregivers: A Retrospective Analysis

  • Ria Paradkar,
  • Christina Regan,
  • Charles P. Nolte,
  • Anthony Stans,
  • William Shaughnessy,
  • Kellen Mulford,
  • Todd A. Milbrandt and
  • A. Noelle Larson

23 December 2024

Background/Objectives: The burden of scoliosis care extends beyond treatment costs and includes missed school for patients and lost income for parents. Chronic absenteeism, defined as more than 18 days of missed school, can have a significant impact...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
5 Citations
2,939 Views
12 Pages

23 December 2024

Background: Although the Spinal Instability Neoplastic Score (SINS) is widely utilized to evaluate spinal instability, its prognostic value for survival in patients with cervical spinal metastases remains unclear. This study investigated the associat...

(This article belongs to the Special Issue Recent Advances in Spine Tumor Diagnosis and Treatment)
  • Article
  • Open Access
2 Citations
3,221 Views
19 Pages

Identifying Risk Factors for Lower Extremity Artery Disease (LEAD) in Cardiology Patients: The Role of Ankle-Brachial Index Measurement

  • Bartosz Zambrzycki,
  • Michał Łuczaj,
  • Marlena Dubatówka,
  • Karolina Dańkowska,
  • Katarzyna Nowicka,
  • Małgorzata Knapp,
  • Anna Szpakowicz,
  • Karol Kamiński and
  • Anna Lisowska

23 December 2024

Background and aims: Lower Extremity Artery Disease (LEAD) is a predictor of atherosclerotic plaques in other locations and significantly increases the risk of death from cardiovascular events. This study aimed to identify cardiology patient subpopul...

(This article belongs to the Special Issue Innovations in Vascular Medicine: Optimizing Patient Care through Peripheral Interventions)
  • Article
  • Open Access
1 Citations
2,038 Views
17 Pages

His108Arg Transthyretin Amyloidosis—Shedding Light on a Distinctively Malignant Variant

  • Christina Binder,
  • Lena Marie Schmid,
  • Christina Kronberger,
  • Michael Poledniczek,
  • René Rettl,
  • Johanna Schlein,
  • Nikita Ermolaev,
  • Luciana Camuz Ligios,
  • Michaela Auer-Grumbach and
  • Franz Duca
  • + 5 authors

23 December 2024

Variant transthyretin amyloidosis cardiomyopathy (ATTRv-CM) is a rare form of cardiac amyloidosis associated with many possible mutations in the transthyretin gene, presenting as various distinct clinical phenotypes. Among these, the His108Arg mutati...

(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Amyloidosis)
  • Article
  • Open Access
4 Citations
2,074 Views
8 Pages

23 December 2024

Introduction: Hysteroscopy is a key gynecological procedure for diagnosing and treating endometrial conditions. While hysteroscopy is often performed in office settings without sedation, patients frequently report significant pain during the procedur...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
1 Citations
1,816 Views
13 Pages

Prognostic Role of Lymphocyte-to-C-Reactive Protein Ratio in Patients with Pulmonary Arterial Hypertension

  • Meng-Qi Chen,
  • Chuan-Xue Wan,
  • Jun Tong,
  • An Wang,
  • Bin-Qian Ruan and
  • Jie-Yan Shen

23 December 2024

Background: Inflammation plays a critical role in the prognosis of patients with pulmonary arterial hypertension (PAH). The lymphocyte-to-C-reactive protein ratio (LCR), as a novel inflammatory marker, has not been studied in patients with PAH. The o...

(This article belongs to the Special Issue Clinical Insights into Pulmonary Hypertension)
  • Article
  • Open Access
6 Citations
1,793 Views
9 Pages

Can Multiparametric Ultrasound Analysis Predict Malignancy in Testes? An 11-Year Single Center Experience with Testicular Masses

  • Yannic Volz,
  • Isabel K. Brinkmann,
  • Dirk-André Clevert,
  • Nikolaos Pyrgidis,
  • Patrick Keller,
  • Philipp Weinhold,
  • Friedrich Jokisch,
  • Marc Kidess,
  • Michael Chaloupka and
  • Julian Marcon
  • + 1 author

23 December 2024

Introduction/Objective: Contrast-enhanced ultrasound (CEUS) is a promising modality for differentiating benign and malignant lesions in various organs, including the testis. Testicular tumors, common in young men, are often treated with radical orchi...

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
4 Citations
2,246 Views
13 Pages

The Uric Acid-to-High-Density Lipoprotein Cholesterol Ratio: A New Biomarker for Predicting Arrhythmia Recurrence After Atrial Fibrillation Ablation

  • Emir Dervis,
  • Eyup Ozkan,
  • Idris Yakut,
  • Hasan Can Konte,
  • Aykun Hakgor,
  • Omer Alyan,
  • Taylan Akgun and
  • Dursun Aras

23 December 2024

Background: We aimed to assess the uric acid-to-high-density lipoprotein cholesterol (HDL-C) ratio (UHR) and several other parameters with respect to their performance in detecting recurrence among patients with atrial fibrillation (AF) who underwent...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
2,134 Views
11 Pages

Minimally Invasive Surgery in Acute Bowel Obstruction: Should It Become the Standard of Care? A Prospective, Single Center, Observational Study

  • Hannes Hoi,
  • Martin Grünbart,
  • Michael de Cillia,
  • Robert Uzel,
  • Hannah Hofer,
  • Lisa Schlosser,
  • Peter Tschann,
  • Helmut Weiss and
  • Christof Mittermair

23 December 2024

Background/Objectives: This study was conducted to determine whether a structured clinical pathway can help to safely implement minimally invasive surgery (MIS) as the standard approach in surgery for acute bowel obstruction (ABO). Methods: A prospec...

(This article belongs to the Special Issue New Insights into Acute Care and Emergency Surgery)
  • Article
  • Open Access
4 Citations
6,291 Views
10 Pages

Evolving Trends and Future Demands in ENT Procedures: A Nationwide 10-Year Analysis

  • Akash Jangan,
  • Satvir Minhas,
  • Emmanuel Diakos,
  • Mark Simmons and
  • Zahir Mughal

23 December 2024

Objective: This study aims to investigate the trends in otology, rhinology, and head and neck (H&N) operations over the past decade in England. These trends will allow for predictive modelling to forecast the demand over the coming years to aid w...

(This article belongs to the Special Issue Current and Future Trends in Otorhinolaryngology–Head and Neck Surgery)
  • Article
  • Open Access
2 Citations
2,448 Views
10 Pages

Prediction Model for Sciatic Nerve Procedures: A Cross-Sectional Study

  • Isabel Minguez-Esteban,
  • Ángel González-de-la-Flor,
  • Jorge Hugo Villafañe,
  • Juan Antonio Valera-Calero,
  • Gustavo Plaza-Manzano,
  • Pedro Belón-Pérez and
  • Carlos Romero-Morales

23 December 2024

Objectives: We aimed to create a predictive model to estimate sciatic nerve depth using anthropometric and demographic data to enhance safety and precession in needle-based interventions. Setting: The study was conducted at Universidad Europea de Mad...

(This article belongs to the Special Issue Musculoskeletal Diagnosis and Treatment: Connecting Gaps to Enhance Patient Care)
  • Article
  • Open Access
1 Citations
1,987 Views
9 Pages

Bulgarian Experience in Vaginal Electronic Brachytherapy for Gynecologic Cancers’ Treatment—First Results

  • Virginia Payakova,
  • Angel Yordanov,
  • Desislava Kostova-Lefterova,
  • Nikolay Mutkurov,
  • Ilko Iliev,
  • Marin Valkov,
  • Elitsa Encheva and
  • Desislava Hitova-Topkarova

23 December 2024

Background/Objectives: The objective of this study is to prospectively collect dosimetric and clinical data on vaginal cuff electronic brachytherapy and propose a protocol for the procedure. Methods: Twenty-five patients who had proven endometrial or...

(This article belongs to the Section Obstetrics & Gynecology)
  • Feature Paper
  • Article
  • Open Access
5 Citations
2,319 Views
13 Pages

A Prospective Study on the Feasibility and Effect of an Optimized Perioperative Care Protocol in Pediatric Neuromuscular Scoliosis Surgery

  • Marie Mostue Naume,
  • Christina Engel Hoei-Hansen,
  • Alfred Peter Born,
  • Ghita Brekke,
  • Astrid Høj,
  • Maja Risager Nielsen,
  • Lise Borgwardt,
  • John Vissing,
  • Jesper Dirks and
  • Mette Cathrine Ørngreen
  • + 3 authors

23 December 2024

Background/Objectives: A recent retrospective study conducted by our team identified a high percentage of postoperative pneumonia in children with neuromuscular scoliosis. Based on the findings in that study and our clinical experience, we aimed to a...

(This article belongs to the Section Clinical Pediatrics)
  • Article
  • Open Access
1 Citations
2,678 Views
12 Pages

Effects on Posture of a Two-Diopter Horizontal Prism Base Out on the Non-Dominant Eye

  • Davide Marini,
  • Giovanni Rubegni,
  • Lorenzo Sarti,
  • Alessandra Rufa,
  • Marco Mandalà,
  • Fabio Ferretti,
  • Gian Marco Tosi and
  • Mario Fruschelli

23 December 2024

Background/Objectives: Ocular proprioception is implicated in balance control and heterophoria is associated with abnormal posture, though previous research focused mainly on the role of vertical phoria and the use of vertical prisms. This study aims...

(This article belongs to the Section Ophthalmology)
  • Review
  • Open Access
12 Citations
11,914 Views
21 Pages

Advances in Atrial Fibrillation Management: A Guide for General Internists

  • Hoang Nhat Pham,
  • Ramzi Ibrahim,
  • Hong Hieu Truong,
  • Enkhtsogt Sainbayar,
  • Viet Nghi Tran,
  • Mahmoud Abdelnabi,
  • Christopher Kanaan and
  • Aadhavi Sridharan

23 December 2024

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, impacting approximately 6.1 million adults in the United States, with projections to increase two-fold by 2030. AF significantly increases the risk of stroke and other adverse...

(This article belongs to the Section Cardiovascular Medicine)
  • Article
  • Open Access
3 Citations
2,491 Views
10 Pages

Factors Associated with In-Hospital Mortality in Adult Patients with Bacterial Meningitis

  • Michał Makowiecki,
  • Marcin Paciorek,
  • Agnieszka Bednarska,
  • Dominika Krogulec,
  • Dawid Porowski,
  • Dominik Bursa,
  • Agata Skrzat-Klapaczyńska,
  • Carlo Bieńkowski,
  • Justyna D. Kowalska and
  • Tomasz Laskus
  • + 2 authors

23 December 2024

Background/Objectives: The aim of this study was to evaluate the association between various clinical and laboratory findings and in-hospital mortality in community-acquired bacterial meningitis (BM). Methods: We retrospectively analyzed 339 adult (&...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
1 Citations
1,948 Views
10 Pages

Development and Validation of a New Adherence Scale for Antiseizure Medications [ASASM]

  • Sarah A. Alotaibi,
  • Noura A. Alrukban,
  • Layla N. Alanizy,
  • Ahmad Saleh and
  • Bshra A. Alsfouk

23 December 2024

Objective: The objective was to develop and validate a multidimensional scale that measures adherence levels to antiseizure medications and detects patients’ reasons for non-adherence. Methods: A new scale was developed, namely the “Adher...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
3,972 Views
11 Pages

A Smartphone App for the Management of Postoperative Home Recovery After Thoracic Surgery Procedures: A Pilot Study Using the Care4Today™ App

  • Pietro Bertoglio,
  • Elena Garelli,
  • Silvia Bonucchi,
  • Jury Brandolini,
  • Kenji Kawamukai,
  • Filippo Antonacci,
  • Sergio Nicola Forti Parri,
  • Barbara Bonfanti,
  • Giulia Lai and
  • Piergiorgio Solli
  • + 1 author

23 December 2024

Background/Objectives: In recent years, the use of smartphones has significantly increased among populations of almost every age. The aim of our work is to analyze the impact of an application (app) that follows up with the progress of a patient who...

(This article belongs to the Special Issue Thoracic Surgery: Current Practice and Future Directions)
  • Article
  • Open Access
1 Citations
3,884 Views
17 Pages

First Diagnostic Questionnaire for Assessing Patients’ Social Functioning: Comprehensive DDX3X Syndrome Patient Profile

  • Urszula Stefaniak-Preis,
  • Ada Kaczmarek,
  • Mirosław Andrusiewicz,
  • Magdalena Roszak,
  • Natalia Trzeszczyńska,
  • Włodzimierz Samborski,
  • Ewa Mojs and
  • Roksana Malak

22 December 2024

Background/Objectives: DDX3X syndrome is often misdiagnosed as autism spectrum disorder (ASD, Rett Syndrome, and Dandy–Walker Syndrome). Precise phenotyping is needed with reference to neurodevelopmental diagnosis. Observation of behavior and c...

(This article belongs to the Section Mental Health)
  • Review
  • Open Access
1 Citations
2,879 Views
20 Pages

22 December 2024

Breast cancer is the most diagnosed cancer globally. While the breast cancer prevalence continues to rise, so too do patient survival rates, thus resulting in a large survivor population. Up to 75% of this population report experiencing cancer-relate...

(This article belongs to the Section Oncology)
  • Review
  • Open Access
2 Citations
6,608 Views
14 Pages

Retinal Vascular Complications in Cocaine Abuse: A Case Report and a Literature Review

  • Marta Armentano,
  • Ludovico Alisi,
  • Giacomo Visioli,
  • Maria Carmela Saturno,
  • Arianna Barba,
  • Alessio Speranzini,
  • Giuseppe Maria Albanese,
  • Magda Gharbiya and
  • Ludovico Iannetti

22 December 2024

This comprehensive review examines the ocular vascular complications of cocaine use, focusing on its effects on retinal vasculature and inflammation. A rare case of bilateral frosted branch angiitis (FBA) in a 48-year-old man with a history of intran...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
3 Citations
3,320 Views
12 Pages

22 December 2024

Background: Hallux valgus is a prevalent foot deformity conventionally treated with open surgical techniques, which carry risk of complications due to extensive soft tissue dissection. Minimally invasive surgeries (MISs) as alternatives offer compara...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
2 Citations
1,726 Views
11 Pages

Characteristics of Microaneurysm Size in Residual Edema After Intravitreal Injection of Faricimab for Diabetic Macular Edema

  • Yutaka Yamada,
  • Yoshihiro Takamura,
  • Masakazu Morioka,
  • Hideyuki Oshima,
  • Makoto Gozawa,
  • Takehiro Matsumura and
  • Masaru Inatani

22 December 2024

Background/Objectives: Microaneurysms (MAs) are important in the pathology of diabetic macular edema (DME) and its response to anti-vascular endothelial growth factor (VEGF) therapy. This study aimed to clarify the morphological characteristics of MA...

(This article belongs to the Special Issue An Update on Retinal Diseases: From Diagnosis to Treatment)
  • Review
  • Open Access
2 Citations
1,776 Views
14 Pages

Application of Original Prostate Cancer Progression Model Interacting with Fibroblasts in Preclinical Research

  • Kenichiro Ishii,
  • Kazuhiro Iguchi,
  • Chise Matsuda,
  • Yoshifumi Hirokawa,
  • Yoshiki Sugimura and
  • Masatoshi Watanabe

22 December 2024

Prostate cancer (PCa) is a heterogeneous disease that exhibits androgen sensitivity and responsiveness to androgen deprivation therapy (ADT). However, ADT induces only temporary remission, and the majority of PCa cases eventually progress to castrati...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
3 Citations
2,062 Views
11 Pages

22 December 2024

Background: Lichen Sclerosus (LSc) is a chronic inflammatory skin condition predominantly affecting the anogenital regions, with a well-recognised potential for malignancy. This study examines the incidence, demographic characteristics, and regional...

(This article belongs to the Section Dermatology)
  • Article
  • Open Access
1 Citations
1,787 Views
9 Pages

22 December 2024

Background: Valve-sparing root replacement surgery is an alternative strategy for patients with aortic regurgitation with or without aortic root enlargement. A detailed understanding of the mechanisms of regurgitation and the morphology of the aortic...

(This article belongs to the Special Issue Surgical Treatment and Postoperative Recovery of Heart and Lung Disease)
  • Case Report
  • Open Access
5 Citations
2,484 Views
10 Pages

Successful Laparoscopy-Assisted Extirpation of Burkitt’s Lymphoma Causing Intestinal Obstruction in a 17-Year-Old Boy

  • Zoltán Derzsi,
  • Zsolt Bara,
  • Emőke Horváth,
  • Gabriel Serac,
  • Răzvan Mărginean,
  • Réka Sólyom,
  • Evelyn Kovács and
  • Horea Gozar

22 December 2024

Background: Childhood extranodal B-cell non-Hodgkin’s lymphomas are often caused by Burkitt’s lymphoma (BL). Treatment usually involves intensive polychemotherapy, and recent prospective trials show significantly improved outcomes. Surger...

(This article belongs to the Section General Surgery)
  • Review
  • Open Access
25 Citations
7,698 Views
26 Pages

AI in Hepatology: Revolutionizing the Diagnosis and Management of Liver Disease

  • Sheza Malik,
  • Rishi Das,
  • Thanita Thongtan,
  • Kathryn Thompson and
  • Nader Dbouk

22 December 2024

The integration of artificial intelligence (AI) into hepatology is revolutionizing the diagnosis and management of liver diseases amidst a rising global burden of conditions like metabolic-associated steatotic liver disease (MASLD). AI harnesses vast...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
2 Citations
2,702 Views
14 Pages

Metabolic Disturbances Associated with In-Hospital Complication and Mortality in Different Types of Pneumonia

  • Iulia Făgărășan,
  • Adriana Rusu,
  • Horațiu Comșa,
  • Maria Cristea,
  • Nicoleta-Ștefania Motoc,
  • Ciprian Cristea,
  • Corina Eugenia Budin,
  • Ruxandra-Mioara Râjnoveanu and
  • Doina Adina Todea

22 December 2024

Bakground: The mortality rate from community-acquired pneumonia (CAP) or coronavirus disease 19 (COVID-19) is high, especially in hospitalized patients. This study aimed to assess the disturbances of glucose and lipid metabolism with in-hospital comp...

(This article belongs to the Special Issue Chronic Lung Conditions: Integrative Approaches to Long-Term Care)
  • Article
  • Open Access
4 Citations
2,610 Views
9 Pages

Incidence and Outcomes of Vertebral Compression Fracture Among Patients Infected with COVID-19

  • Helen Zhang,
  • Mariah Balmaceno-Criss,
  • Abigail M. Fruge,
  • Patrick A. Massey,
  • Alan H. Daniels and
  • Andrew S. Zhang

22 December 2024

Background/Objectives: Early studies have suggested that the SARS-CoV-2 virus has a deleterious effect on bone mineral density and may increase the risk of pathological fractures. This study characterized vertebral compression fractures in patients w...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
3 Citations
2,870 Views
11 Pages

Intraoral Approach Through the Nasal Floor for Surgical Removal of Inverted Mesiodens: Protocol and Case Series

  • Horatiu Urechescu,
  • Ancuta Banu,
  • Felicia Streian,
  • Florin Urtila,
  • Cristiana Cuzic,
  • Stefania Dinu and
  • Marius Pricop

22 December 2024

Background/Objectives: The most common form of supernumerary teeth is represented by the mesiodens. Very often, they are impacted, usually palatially, but can be found buccally or between the roots of the permanent central incisors. Their position ca...

(This article belongs to the Special Issue Clinical Research of Novel Therapeutic Approaches in Dentistry (2nd Edition))
  • Article
  • Open Access
5 Citations
2,083 Views
13 Pages

22 December 2024

Background/Objectives: Female sex is one of the Long COVID (LC) risk factors; however, the LC predictors in females have not been established. This study was conducted to assess the influence of LC on the cardiovascular system and to assess the age-i...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
2,703 Views
11 Pages

Nd:Yag Laser Transluminal Embolysis: A Therapeutic Approach in Retinal Artery Occlusion

  • Bogdana Tăbăcaru,
  • George Abboud,
  • Mihnea Munteanu,
  • Simona Stanca and
  • Horia Tudor Stanca

22 December 2024

Background: Central and branch retinal artery occlusion (CRAO and BRAO) are critical causes of acute vision loss, predominantly affecting older adults with systemic vascular pathology. These occlusions typically result from embolic events, leading to...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
1 Citations
2,299 Views
22 Pages

Diabetic Nephropathy-Associated Impaired Aortic Function Is Not Mediated by Mean Arterial Pressure and Its Determinants

  • Hon-Chun Hsu,
  • Makabongwe S’kholiwe Mazibuko,
  • Chanel Robinson,
  • Noluntu Dlongolo,
  • Angela Woodiwiss,
  • Gloria Teckie,
  • Grace Tade and
  • Patrick Hector Dessein

21 December 2024

Objective: The study aimed to assess the potential impacts of mean arterial pressure (MAP) and its determinants (cardiac output and systemic vascular resistance) on diabetic nephropathy (DNP)-associated impaired aortic function. Methods: This multi-e...

(This article belongs to the Section Nephrology & Urology)
  • Review
  • Open Access
4 Citations
9,419 Views
14 Pages

Conservative Treatment of Neonatal Brachial Plexus Palsy: A Narrative Review

  • Valentina Boetto,
  • Anna Markova,
  • Federica Malgrati,
  • Isabel Bongiovanni,
  • Anna Bassetto,
  • Chiara Pavese,
  • Antonio Nardone,
  • Giuseppe Massazza,
  • Gabriele Colò and
  • Paolo Titolo

21 December 2024

Neonatal brachial plexus palsy (NBPP) is a flaccid paralysis of the upper limbs that occurs in about 0.4 percent of live births. This condition can produce permanent disabilities; to date, there is no consensus on protocols to be applied for the reha...

(This article belongs to the Special Issue Acute Care for Traumatic Injuries and Surgical Outcomes)
  • Article
  • Open Access
10 Citations
10,040 Views
18 Pages

21 December 2024

Background/Objectives: The COVID-19 pandemic highlighted that body positions substantially affected the mortality rate. We hypothesized that body position modulates the contribution of abdominal (AB) and thoracic breathing (TB) to the breathing cycle...

(This article belongs to the Special Issue Sports Exercise: How It Benefits Health and Disease)
  • Article
  • Open Access
3 Citations
2,336 Views
8 Pages

21 December 2024

Background: Irinotecan is a topoisomerase I inhibitor used for the treatment of various cancers, such as gastrointestinal, pancreatic, pulmonary, ovarian, and cervical cancers. Among chemotherapy agents, it represents a rare trigger of drug hype...

(This article belongs to the Section Dermatology)
  • Article
  • Open Access
2 Citations
2,432 Views
13 Pages

High Prevalence of Severe Depression in Mexican Patients Diagnosed with HIV Treated with Efavirenz and Atazanavir: Clinical Follow-Up at Four Weeks and Analysis of TPH2 SNPs

  • Sandra Angélica Rojas-Osornio,
  • Francisco Guerra-Castillo,
  • Antonio Mata-Marín,
  • Vladimir Paredes-Cervantes,
  • Charmina Aguirre-Alvarado,
  • Carolina Bekker-Méndez,
  • Gilberto Pérez-Sánchez,
  • José Molina-López,
  • Mónica Ortiz-Maganda and
  • Emiliano Tesoro-Cruz
  • + 1 author

21 December 2024

Efavirenz (EFV) causes neuropsychiatric effects such as anxiety, depression, and suicidal thoughts in people with HIV (PWH). Depressive disorders have been associated with the Tryptophan hydroxylase type 2 (TPH2) gene. Objectives: This study determin...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
2 Citations
1,957 Views
12 Pages

21 December 2024

Background/Objectives: Chronic neuropathic pain (CNP) stands as one of the most debilitating complications in patients with myelitis owing to its challenging management. Bright spotty lesions (BSLs) are frequently observed in neuromyelitis optica spe...

(This article belongs to the Special Issue Clinical Perspectives for Headache and Neuropathic Pain)
  • Review
  • Open Access
16 Citations
42,974 Views
24 Pages

Complexities, Benefits, Risks, and Clinical Implications of Sodium Bicarbonate Administration in Critically Ill Patients: A State-of-the-Art Review

  • Akram M. Eraky,
  • Yashwanth Yerramalla,
  • Adnan Khan,
  • Yasser Mokhtar,
  • Alisha Wright,
  • Walaa Alsabbagh,
  • Kevin Franco Valle,
  • Mina Haleem,
  • Kyle Kennedy and
  • Chad Boulware

21 December 2024

Sodium bicarbonate has been used in the treatment of different pathologies, such as hyperkalemia, cardiac arrest, tricyclic antidepressant toxicity, aspirin toxicity, acute acidosis, lactic acidosis, diabetic ketoacidosis, rhabdomyolysis, and adrener...

(This article belongs to the Section Intensive Care)
  • Article
  • Open Access
2,269 Views
11 Pages

21 December 2024

Background/Objectives: Recurrent lumbar disc herniation (RLDH) refers to a lumbar disc herniation (LDH) that recurs at the same level, location, and side following surgical repair. This study aimed to evaluate the efficacy of transforaminal epidural...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
6 Citations
2,907 Views
12 Pages

The First Report on Liver Resection Using the Novel Japanese hinotori™ Surgical Robot System: First Case Series Report of 10 Cases

  • Kenichi Nakamura,
  • Tetsuya Koide,
  • Takahiko Higashiguchi,
  • Kazuhiro Matsuo,
  • Tomoyoshi Endo,
  • Kenji Kikuchi,
  • Koji Morohara,
  • Hidetoshi Katsuno,
  • Ichiro Uyama and
  • Zenichi Morise
  • + 1 author

21 December 2024

Background: In Japan, the hinotori™ surgical robot system (Medicaroid Corporation, Kobe, Japan) was approved for gastrointestinal surgeries in October 2022. This report details our initial experience performing liver resection using the hinotor...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Review
  • Open Access
45 Citations
27,440 Views
22 Pages

A Comprehensive Review of Catheter-Related Thrombosis

  • Marina López-Rubio,
  • Marta-Olimpia Lago-Rodríguez,
  • Lucía Ordieres-Ortega,
  • Crhistian-Mario Oblitas,
  • Sergio Moragón-Ledesma,
  • Rubén Alonso-Beato,
  • Luis-Antonio Alvarez-Sala-Walther and
  • Francisco Galeano-Valle

21 December 2024

Catheter-related thrombosis (CRT) is a frequent and potentially serious complication associated with the widespread use of intravascular devices such as central venous catheters, including peripherally inserted central catheters and implantable port...

(This article belongs to the Special Issue Deep Vein Thrombosis and Pulmonary Embolism: Clinical Treatment and Management)
  • Systematic Review
  • Open Access
4 Citations
8,151 Views
9 Pages

Systematic Review of Acute Isolated Distal Radioulnar Joint Dislocation: Treatment Options

  • Konstantinos Zampetakis,
  • Ioannis M. Stavrakakis,
  • Kalliopi Alpantaki,
  • Grigorios Kastanis,
  • Ioannis Ktistakis,
  • Alexandros Tsioupros,
  • Nikolaos Ritzakis and
  • Constantinos Chaniotakis

21 December 2024

Background/Objectives: Acute isolated distal radioulnar joint (DRUJ) dislocations are rare and often misdiagnosed during initial evaluation due to subtle clinical presentation, low index of suspicion, and imaging barriers. Prompt diagnosis and treatm...

(This article belongs to the Special Issue Advances in Trauma and Orthopedic Surgery: 2nd Edition)

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J. Clin. Med. - ISSN 2077-0383