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Microorganisms, Volume 13, Issue 1

2025 January - 214 articles

Cover Story: For decades, Alzheimer’s Disease (AD) research has focused on the amyloid cascade hypothesis, which identifies amyloid-beta (Aβ) as the primary driver of the disease. However, the consistent failure of Aβ-targeted therapies to demonstrate efficacy, coupled with significant safety concerns, underscores the need to rethink our approach to AD treatment. This review explores unconventional perspectives and emerging paradigms regarding microbial involvement in AD pathogenesis, emphasizing the gut–brain axis, brain biofilms, the oral microbiome, and viral infections. We also discuss potential microbiome-based therapies, including fecal microbiota transplantation (FMT), probiotics, prebiotics, antiviral treatments, and vaccines, as promising strategies for managing and potentially preventing AD progression. View this paper
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Articles (214)

  • Article
  • Open Access
1 Citations
1,934 Views
16 Pages

As transitional ecosystems between land and sea, estuaries are characterized by a unique environment that supports complex and diverse microbial communities. A comprehensive analysis of microbial diversity and ecological processes at different trophi...

  • Article
  • Open Access
1 Citations
1,498 Views
11 Pages

Anti-Tick-Bourne Encephalitis IgM Intrathecal Synthesis as a Prediction Marker in Tick-Borne Encephalitis Patients

  • Piotr Czupryna,
  • Sambor Grygorczuk,
  • Agnieszka Siemieniako-Werszko,
  • Jakub Okrzeja,
  • Justyna Dunaj-Małyszko,
  • Justyna Adamczuk,
  • Sławomir Pancewicz,
  • Joanna Zajkowska,
  • Karolina Narejko and
  • Anna Moniuszko-Malinowska
  • + 2 authors

The aim of this study was to evaluate the usefulness of IgM anti-Tick-Borne Encephalitis (anti-TBE) intrathecal synthesis in the diagnosis and prediction of the clinical course of the disease. Thirty-six patients were included in the study (patients...

  • Article
  • Open Access
1 Citations
1,446 Views
12 Pages

NupR Is Involved in the Control of PlcR: A Pleiotropic Regulator of Extracellular Virulence Factors

  • Jiaxin Qin,
  • Ziqi Wang,
  • Cheng Qian,
  • Guohui Ji,
  • Yizhuo Zhang,
  • Zhanglei Cao,
  • Bing Yan and
  • Jun Cai

NupR is a nucleoside permease regulator belonging to the GntR family, mainly regulating nucleoside transport in Bacillus thuringiensis. A conserved binding site for NupR was found in the promoter region of plcR. This study aimed to investigate the re...

  • Article
  • Open Access
1,730 Views
15 Pages

Antibacterial Potential of Crude Extracts from Cylindrospermum alatosporum NR125682 and Loriellopsis cavernicola NR117881

  • Albert Olufemi Ikhane,
  • Foluso Oluwagbemiga Osunsanmi,
  • Rebamang Anthony Mosa and
  • Andrew Rowland Opoku

The challenges of antimicrobial resistance (AMR) to human health have pushed for the discovery of a new antibiotics agent from natural products. Cyanobacteria are oxygen-producing photosynthetic prokaryotes found in a variety of water habitats. Secon...

  • Article
  • Open Access
7 Citations
2,394 Views
19 Pages

The Isolation of Lead-Tolerant PGPR from Red Clover Soil and Its Role in Promoting the Growth of Alfalfa

  • Wanting Nie,
  • Yuchen Wu,
  • Jingwen Jiang,
  • Zicheng Wang,
  • Meiqi Mu,
  • Siwen Zhao,
  • Minghao Yang,
  • Xi Long,
  • Xiujie Yin and
  • Xiaohua Teng

Alfalfa (Medicago sativa L.) is an outstanding species used for the remediation of heavy metal-contaminated soil, and our previous research has shown that PGPR can promote plant growth under high-concentration lead stress. This discovery has forced s...

  • Article
  • Open Access
6 Citations
3,240 Views
13 Pages

Prevalence and Antibiotic Resistance of Escherichia coli Isolated from Raw Cow’s Milk

  • Roxana Ionela Drugea,
  • Mădălina Iulia Siteavu,
  • Elena Pitoiu,
  • Cristina Delcaru,
  • Ecaterina Monica Sârbu,
  • Carmen Postolache and
  • Stelian Bărăităreanu

Escherichia coli (E. coli) is one of the most common pathogens in both humans and livestock. This study aimed to investigate the prevalence of E. coli isolated from raw cow milk and evaluate its antimicrobial resistance rates. A total of 1696 mi...

  • Article
  • Open Access
5 Citations
2,585 Views
16 Pages

Comparative Genomic Analysis of Campylobacter Plasmids Identified in Food Isolates

  • Yiping He,
  • Gretchen Elizabeth Dykes,
  • Siddhartha Kanrar,
  • Yanhong Liu,
  • Nereus W. Gunther,
  • Katrina L. Counihan,
  • Joe Lee and
  • Joseph A. Capobianco

Campylobacter is one of the leading bacterial causes of gastroenteritis worldwide. It frequently contaminates poultry and other raw meat products, which are the primary sources of Campylobacter infections in humans. Plasmids, known as important mobil...

  • Article
  • Open Access
5 Citations
2,626 Views
20 Pages

Association Analysis of the Genomic and Functional Characteristics of Halotolerant Glutamicibacter endophyticus J2-5-19 from the Rhizosphere of Suaeda salsa

  • Longhao Sun,
  • Shanshan Sun,
  • Tianyang Liu,
  • Xinmin Lei,
  • Ruiqi Liu,
  • Junyi Zhang,
  • Shanshan Dai,
  • Jing Li and
  • Yanqin Ding

Halotolerant plant growth-promoting bacteria (HT-PGPB) have attracted considerable attention for their significant potential in mitigating salt stress in crops. However, the current exploration and development of HT-PGPB remain insufficient to meet t...

  • Review
  • Open Access
7 Citations
5,027 Views
14 Pages

Fungal Infections in Kidney Transplant Recipients: A Comprehensive Narrative Review

  • Maria Mazzitelli,
  • Federico Nalesso,
  • Alberto Enrico Maraolo,
  • Vincenzo Scaglione,
  • Lucrezia Furian and
  • Annamaria Cattelan

Background: Despite kidney transplantation being a life-saving procedure, patients experience a high risk of developing fungal infections (FIs), with an increased risk of both morbidity and mortality, especially during the first year after transplant...

  • Article
  • Open Access
3 Citations
2,618 Views
18 Pages

Biodegradation of Phenol at High Initial Concentration by Rhodococcus opacus 3D Strain: Biochemical and Genetic Aspects

  • Tatiana O. Anokhina,
  • Tatiana Z. Esikova,
  • Valentina N. Polivtseva,
  • Nataliya E. Suzina and
  • Inna P. Solyanikova

Phenolic compounds are an extensive group of natural and anthropogenic organic substances of the aromatic series containing one or more hydroxyl groups. The main sources of phenols entering the environment are waste from metallurgy and coke plants, e...

  • Article
  • Open Access
2 Citations
2,066 Views
15 Pages

Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries

  • Tiziano A. Schweizer,
  • Julia S. Würmli,
  • Julia Prinz,
  • Maximilian Wölfle,
  • Roger Marti,
  • Hendrik Koliwer-Brandl,
  • Ashley M. Rooney,
  • Vanni Benvenga,
  • Adrian Egli and
  • Yvonne Achermann
  • + 2 authors

Classical preoperative skin antisepsis is insufficient in completely eliminating bacterial skin colonization for arthroplasty. In contrast, photodynamic therapy (PDT) with red light and methyl-aminolevulinate (MAL), combined with skin antisepsis, led...

  • Article
  • Open Access
3 Citations
1,867 Views
19 Pages

Increased application of organic fertilizer is an effective measure to improve greenhouse soil quality. However, prolonged and intensive application of organic manure has caused nutrient and certain heavy metal accumulation in greenhouse soil. Theref...

  • Article
  • Open Access
4 Citations
2,244 Views
12 Pages

Phenolic compounds are industrially versatile chemicals that have been successfully produced in microbial cell factories. Unfortunately, most phenolic compounds are highly toxic to cells in specific cellular environments or above a particular concent...

  • Communication
  • Open Access
1,274 Views
8 Pages

Clinical Evaluation of a Rapid Reciprocal-Flow PCR Assay and Real-Time PCR Assay with Quenching Probe for Detection of Mycobacterium tuberculosis Complex

  • Kosuke Kosai,
  • Keisuke Matsumoto,
  • Takahisa Ishikawa,
  • Yasuhide Kawamoto,
  • Norihiko Akamatsu,
  • Kenji Ota,
  • Fujiko Mitsumoto-Kaseida,
  • Norihito Kaku,
  • Hiroo Hasegawa and
  • Katsunori Yanagihara
  • + 2 authors

This study investigated the diagnostic efficiencies of two assays for the detection of Mycobacterium tuberculosis complex: (1) the reciprocal-flow real-time polymerase chain reaction (PCR)-based GeneSoC assay and (2) the real-time PCR based GENECUBE...

  • Article
  • Open Access
2 Citations
1,729 Views
16 Pages

Emerging evidence indicates a close relationship between gut microbiota and fatty liver disease. It has been suggested that gut microbiota modulation with probiotics ameliorates fatty liver disease in rodents and humans, yet it remains unclear whethe...

  • Article
  • Open Access
1 Citations
1,610 Views
12 Pages

Coxsackievirus B (CVB) infections, ranging from mild to severe diseases, lack specific antiviral treatments, underscoring the need for novel therapeutic strategies. Drug therapy is an important tool for controlling enterovirus infections, but clinica...

  • Article
  • Open Access
8 Citations
2,208 Views
21 Pages

Beyond Microbial Variability: Disclosing the Functional Redundancy of the Core Gut Microbiota of Farmed Gilthead Sea Bream from a Bayesian Network Perspective

  • Federico Moroni,
  • Fernando Naya-Català,
  • Ahmed Ibrahem Hafez,
  • Ricardo Domingo-Bretón,
  • Beatriz Soriano,
  • Carlos Llorens and
  • Jaume Pérez-Sánchez

The significant microbiota variability represents a key feature that makes the full comprehension of the functional interaction between microbiota and the host an ongoing challenge. To overcome this limitation, in this study, fish intestinal microbio...

  • Review
  • Open Access
14 Citations
8,459 Views
13 Pages

Chronic Endometritis and Antimicrobial Resistance: Towards a Multidrug-Resistant Endometritis? An Expert Opinion

  • Francesco Di Gennaro,
  • Giacomo Guido,
  • Luisa Frallonardo,
  • Laura Pennazzi,
  • Miriana Bevilacqua,
  • Pietro Locantore,
  • Amerigo Vitagliano,
  • Annalisa Saracino and
  • Ettore Cicinelli

Chronic endometritis (CE) is a persistent inflammatory condition of the endometrium characterized by abnormal infiltration of plasma cells into the endometrial stroma. Frequently associated with repeated implantation failure, recurrent pregnancy loss...

  • Article
  • Open Access
3 Citations
1,763 Views
20 Pages

Risk Factors and Circulating Subtypes of Cryptosporidium spp. and Giardia duodenalis in Hospitalized Children in Mozambique

  • Ofélia Nhambirre,
  • Maria Luísa Lobo,
  • Idalécia Cossa-Moiane,
  • Adilson Bauhofer,
  • Nilsa de Deus and
  • Olga Matos

Cryptosporidium spp. and Giardia duodenalis are important diarrheal agents in children in developing countries. Little is known about their molecular epidemiology; as such, the objective of this study was to determine the risk factors and genetic div...

  • Article
  • Open Access
3 Citations
2,613 Views
19 Pages

First Detection and Genomic Characterization of Linezolid-Resistant Enterococcus faecalis Clinical Isolates in Bulgaria

  • Tanya V. Strateva,
  • Preslava Hristova,
  • Temenuga J. Stoeva,
  • Hristina Hitkova and
  • Slavil Peykov

Linezolid is an oxazolidinone antibiotic and is considered a last-resort treatment option for serious infections caused by problematic Gram-positive pathogens, including vancomycin-resistant enterococci. The present study aimed to explore the linezol...

  • Article
  • Open Access
1,836 Views
21 Pages

Radiation-induced skin toxicity, resulting from ionizing or nonionizing radiation, is a common skin disorder. However, the underlying relationship between skin microbiota and radiation-induced skin toxicity remains largely unexplored. Herein, we unco...

  • Article
  • Open Access
3 Citations
2,023 Views
19 Pages

Phenotypic Profiling of Selected Cellulolytic Strains to Develop a Crop Residue-Decomposing Bacterial Consortium

  • Arman Shamshitov,
  • Egidija Satkevičiūtė,
  • Francesca Decorosi,
  • Carlo Viti and
  • Skaidrė Supronienė

Slow decomposition rates of cereal crop residues can lead to agronomic challenges, such as nutrient immobilization, delayed soil warming, and increased pest pressures. In this regard, microbial inoculation with efficient strains offers a viable and e...

  • Article
  • Open Access
2 Citations
2,764 Views
15 Pages

Beneficial Effects of In Vitro Reconstructed Human Gut Microbiota by Ginseng Extract Fermentation on Intestinal Cell Lines

  • Margherita Finazzi,
  • Federica Bovio,
  • Matilde Forcella,
  • Marina Lasagni,
  • Paola Fusi and
  • Patrizia Di Gennaro

Oxidative stress caused by reactive oxygen species (ROS) affects the aging process and increases the likelihood of several diseases. A new frontier in its prevention includes bioactive foods and natural extracts that can be introduced by the diet in...

  • Article
  • Open Access
5 Citations
1,819 Views
19 Pages

Comparative Analysis of In Vivo and In Vitro Virulence Among Foodborne and Clinical Listeria monocytogenes Strains

  • Hui Yan,
  • Biyao Xu,
  • Binru Gao,
  • Yunyan Xu,
  • Xuejuan Xia,
  • Yue Ma,
  • Xiaojie Qin,
  • Qingli Dong,
  • Takashi Hirata and
  • Zhuosi Li

Listeria monocytogenes is one of the most important foodborne pathogens that can cause invasive listeriosis. In this study, the virulence levels of 26 strains of L. monocytogenes isolated from food and clinical samples in Shanghai, China, between 202...

  • Article
  • Open Access
2 Citations
2,216 Views
12 Pages

Impact of the COVID-19 Pandemic on Epidemiological Trends in Pediatric Cervical Abscess-Forming Infections

  • Shuhei Takahashi,
  • Ai Kishino,
  • Kentaro Miyai,
  • Shigeru Takishima,
  • Tae Omori,
  • Hidehiro Furuno,
  • Ryosei Iemura,
  • Makoto Ono,
  • Keisuke Ogasawara and
  • Masayuki Nagasawa
  • + 1 author

Abscess-forming cervical bacterial infections are rare and serious infections. Methods: We retrospectively examined the trends in abscess-forming cervical bacterial infections in children who required inpatient treatment in three periods before (Janu...

  • Review
  • Open Access
1 Citations
2,383 Views
14 Pages

Relationship Between the Host Plant Range of Insects and Symbiont Bacteria

  • Doudou Ge,
  • Chongwen Yin,
  • Jiayu Jing,
  • Zhihong Li and
  • Lijun Liu

The evolution of phytophagous insects has resulted in the development of feeding specializations that are unique to this group. The majority of current research on insect palatability has concentrated on aspects of ecology and biology, with relativel...

  • Article
  • Open Access
3,558 Views
14 Pages

Vaginal Dysbiosis in Infertility: A Comparative Analysis Between Women with Primary and Secondary Infertility

  • Iliana Alejandra Cortés-Ortíz,
  • Gustavo Acosta-Altamirano,
  • Rafael Nambo-Venegas,
  • Jesús Alejandro Pineda-Migranas,
  • Oscar Giovanni Ríos-Hernández,
  • Eduardo García-Moncada,
  • Alejandra Yareth Bonilla-Cortés,
  • Mónica Sierra-Martínez and
  • Juan Carlos Bravata-Alcántara

Infertility, both primary and secondary, is strongly influenced by microbiological factors, with the vaginal microbiota playing a key role in reproductive health. Objective: The aim of this study was to characterize the vaginal microbiota of 136 Mexi...

  • Article
  • Open Access
15 Citations
6,860 Views
21 Pages

Four Decades of Bacillus Biofertilizers: Advances and Future Prospects in Agriculture

  • Xinmai Wu,
  • Yan Liu,
  • Baolei Jia,
  • Lili Tao,
  • Han Li,
  • Jingbang Wang,
  • Ziqi Yuan,
  • Xiaobao Sun and
  • Yanlai Yao

Over the past four decades, Bacillus biofertilizers, which are microbial formulations based on Bacillus species, have significantly contributed to sustainable agriculture by enhancing crop growth, improving soil health, and reducing the dependency on...

  • Article
  • Open Access
4 Citations
1,992 Views
16 Pages

Improving Geldanamycin Production in Streptomyces geldanamycininus Through UV Mutagenesis of Protoplast

  • Yuan Yuan,
  • Lu Yang,
  • Zhikai Fang,
  • Haimin Chen,
  • Fei Sun,
  • Hong Jiang and
  • Jian Zhou

Geldanamycin, a benzoquinone ansa antibiotic, has been extensively applied in medical, agricultural, and health research areas due to its antitumor, antifungal, herbicidal, and antiradiation effects. In this study, an improvement of geldanamycin prod...

  • Article
  • Open Access
6 Citations
3,171 Views
24 Pages

Individual differences in environmental sensitivity are linked to stress-related psychiatric symptoms. In previous research, we found that high environmental sensitivity can be a risk factor for increased inflammation and gut permeability, particular...

  • Article
  • Open Access
3 Citations
2,062 Views
15 Pages

Up to one-quarter of the United States population is affected by tinea pedis (athlete’s foot). Tinea pedis of the web space (interdigital tinea pedis) is a common clinical presentation causing skin macerations and fissures. A “dermatophyt...

  • Article
  • Open Access
2,192 Views
11 Pages

Bloodstream Infections in Critical Care Units in England, April 2017 to March 2023: Results from the First Six Years of a National Surveillance Programme

  • Olivia D. Conroy,
  • Andrea Mazzella,
  • Hannah Choi,
  • Jocelyn Elmes,
  • Matt Wilson,
  • Dimple Y. Chudasama,
  • Sarah M. Gerver,
  • Miroslava Mihalkova,
  • Andrew Rhodes and
  • Russell Hope
  • + 3 authors

Background: Patients in critical care units (CCUs) are at an increased risk of bloodstream infections (BSIs), which can be associated with central vascular catheters (CVCs). This study describes BSIs, CVC-BSIs, organism distribution, percentage of an...

  • Article
  • Open Access
6 Citations
4,552 Views
18 Pages

Bioactive compounds and organic acids are applied to a wide range of foods against different types of foodborne pathogens. In the present study, carvacrol and thymol (1000 mg/L) were applied in wine-based marinades, alone or in combination with them...

  • Article
  • Open Access
4 Citations
2,338 Views
19 Pages

Staphylococcus aureus Proteins Implicated in the Reduced Virulence of sarA and sarA/agr Mutants in Osteomyelitis

  • Karen E. Beenken,
  • Mara J. Campbell,
  • Stephanie D. Byrum,
  • Rick D. Edmondson,
  • Samuel G. Mackintosh,
  • Alan J. Tackett and
  • Mark S. Smeltzer

Using a murine osteomyelitis model, we recently demonstrated that Staphylococcus aureus sarA and sarA/agr mutants generated in the USA300 strain LAC are attenuated to a greater extent than an isogenic agr mutant and that this can be attributed to a s...

  • Article
  • Open Access
1,793 Views
16 Pages

Dissemination of IncQ1 Plasmids Harboring NTEKPC-IId in a Brazilian Hospital

  • Camila Maria dos Santos Boralli,
  • Julian Andres Paganini,
  • Rodrigo Silva Meneses,
  • Camila Pacheco Silveira Martins da Mata,
  • Edna Marilea Meireles Leite,
  • Anita C. Schürch,
  • Fernanda L. Paganelli,
  • Rob J. L. Willems and
  • Ilana L. B. C. Camargo

KPC is a clinically significant serine carbapenemase in most countries, and its rapid spread threatens global public health. blaKPC transmission is commonly mediated by Tn4401 transposons. The blaKPC gene has also been found in non-Tn4401 elements (N...

  • Review
  • Open Access
10 Citations
6,924 Views
18 Pages

Pediatric tuberculosis (TB) is still challenged by several diagnostic bottlenecks, imposing a high TB burden in low- and middle-income countries (LMICs). Diagnostic turnaround time (TAT) and ease of operation to suit resource-limited settings are cri...

  • Article
  • Open Access
2 Citations
3,514 Views
15 Pages

Characterization of Streptococcus pyogenes Strains from Tonsillopharyngitis and Scarlet Fever Resurgence, 2023—FIRST Detection of M1UK in Bulgaria

  • Emma Keuleyan,
  • Theodor Todorov,
  • Deyan Donchev,
  • Ani Kevorkyan,
  • Radoslava Vazharova,
  • Alexander Kukov,
  • Georgi Todorov,
  • Boriana Georgieva,
  • Iskra Altankova and
  • Yordanka Uzunova

Recently a resurgence of Streptococcus pyogenes infections has arisen, with concerns around the highly virulent M1UK lineage. Our aim was to characterize S. pyogenes, the immune responses it causes, and to determine the presence of the M1UK lineage i...

  • Article
  • Open Access
4 Citations
4,063 Views
19 Pages

In Vitro Determination of Antimicrobial, Antioxidant and Antiviral Properties of Greek Plant Extracts

  • Aliki Tsakni,
  • Eirini Kyriakopoulou,
  • Sophia Letsiou,
  • Panagiotis Halvatsiotis,
  • Haralambos Rigopoulos,
  • Niki Vassilaki and
  • Dimitra Houhoula

The medicinal potential of plant extracts, especially their antimicrobial, antioxidant, antiviral and cytotoxic properties, has gained significant attention in recent years. This study examined the in vitro bioactivities of several selected Greek med...

  • Article
  • Open Access
2 Citations
2,472 Views
18 Pages

Clonality and the Phenotype–Genotype Correlation of Antimicrobial Resistance in Acinetobacter baumannii Isolates: A Multicenter Study of Clinical Isolates from Romania

  • Adrian-Gabriel Pană,
  • Pavel Șchiopu,
  • Dan Alexandru Țoc,
  • Vlad Sever Neculicioiu,
  • Anca Butiuc-Keul,
  • Anca Farkas,
  • Matei-Ștefan Dobrescu,
  • Mirela Flonta,
  • Carmen Costache and
  • Lia-Monica Junie
  • + 1 author

Antibiotic resistance is on the WHO’s top 10 list of global public health threats due to its rapid emergence and spread but also because of the high morbidity and mortality associated with it. Amongst the main species driving this phenomenon is...

  • Review
  • Open Access
10 Citations
5,401 Views
21 Pages

Halophilic Fungi—Features and Potential Applications

  • Lyudmila Yovchevska,
  • Yana Gocheva,
  • Galina Stoyancheva,
  • Jeny Miteva-Staleva,
  • Vladislava Dishliyska,
  • Radoslav Abrashev,
  • Tsvetomira Stamenova,
  • Maria Angelova and
  • Ekaterina Krumova

Extremophiles are of significant scientific interest due to their unique adaptation to harsh environmental conditions and their potential for diverse biotechnological applications. Among these extremophiles, filamentous fungi adapted to high-salt env...

  • Article
  • Open Access
8 Citations
4,949 Views
27 Pages

Enhanced MICP for Soil Improvement and Heavy Metal Remediation: Insights from Landfill Leachate-Derived Ureolytic Bacterial Consortium

  • Armstrong Ighodalo Omoregie,
  • Fock-Kui Kan,
  • Hazlami Fikri Basri,
  • Muhammad Oliver Ensor Silini and
  • Adharsh Rajasekar

This study investigates the potential of microbial-induced calcium carbonate precipitation (MICP) for soil stabilization and heavy metal immobilization, utilizing landfill leachate-derived ureolytic consortium. Experimental conditions identified yeas...

  • Article
  • Open Access
1,263 Views
18 Pages

Fertilization Induced Soil Microbial Shifts Show Minor Effects on Sapindus mukorossi Yield

  • Juntao Liu,
  • Zhexiu Yu,
  • Yingyun Gong,
  • Jie Chen,
  • Ling Zhou,
  • Weihua Zhang and
  • Liming Jia

Fertilization can improve soil nutrition and increase the yield of Sapindus mukorossi, but the response of soil microbial communities to fertilization treatments and their correlation with soil nutrition and Sapindus mukorossi yield are unclear. In o...

  • Review
  • Open Access
4 Citations
2,483 Views
28 Pages

The pervasive and often indiscriminate use of antibiotics has accelerated the emergence of drug-resistant bacterial strains, thus presenting an acute threat to global public health. Despite a growing acknowledgment of the severity of this crisis, the...

  • Review
  • Open Access
6 Citations
4,518 Views
32 Pages

Animal Brucellosis in Egypt: Review on Evolution, Epidemiological Situation, Prevalent Brucella Strains, Genetic Diversity, and Assessment of Implemented National Control Measures

  • Ahmed M. S. Menshawy,
  • Acacia Ferreira Vicente,
  • Yamen M. Hegazy,
  • Vitomir Djokic,
  • Mahmoud E. R. Hamdy,
  • Luca Freddi,
  • Essam M. Elbauomy,
  • Ashraf E. Sayour,
  • Claire Ponsart and
  • Nour H. Abdel-Hamid

Brucellosis is a neglected zoonotic disease that has a significant economic and public health impact, especially in endemic countries. This review delves deeply into brucellosis’s current epidemiological situation and potential sources of lives...

  • Review
  • Open Access
6 Citations
3,364 Views
14 Pages

The Role and the Regulation of NLRP3 Inflammasome in Irritable Bowel Syndrome: A Narrative Review

  • Arezina Kasti,
  • Konstantinos Katsas,
  • Maroulla D. Nikolaki and
  • Konstantinos Triantafyllou

Irritable bowel syndrome (IBS) is a chronic disorder of the gastrointestinal tract. Its pathogenesis involves multiple factors, including visceral hypersensitivity and immune activation. NLRP3 inflammasome is part of the nucleotide-binding oligomeriz...

  • Article
  • Open Access
2 Citations
2,687 Views
12 Pages

Exploring Metal Ions as Potential Antimicrobial Agents to Combat Future Drug Resistance in Mycoplasma bovis

  • Mauida F. Hasoon Alkhallawi,
  • Majed H. Mohammed,
  • Farhid Hemmatzadeh and
  • Kiro Petrovski

The rise in antimicrobial resistance (AMR) in Mycoplasma bovis underscores the urgent need for alternative treatments. This study evaluated the minimal inhibitory concentrations (MICs) of four metal ions (cobalt, copper, silver, and zinc) and colloid...

  • Article
  • Open Access
4 Citations
3,219 Views
23 Pages

Microbial Contamination and Food Safety Aspects of Cassava Roasted Flour (“Rale”) in Mozambique

  • Andreia Massamby,
  • Su-lin L. Leong,
  • Bettina Müller,
  • Lucas Tivana,
  • Volkmar Passoth,
  • Custódia Macuamule and
  • Mats Sandgren

Cassava is an important staple food that contributes to the food security of small-scale Mozambican farmers. In southern Mozambique, cassava roots are usually processed into cassava roasted flour, locally known as “rale”. The handling and...

  • Review
  • Open Access
15 Citations
7,139 Views
23 Pages

Virulence of Bacteria Causing Mastitis in Dairy Cows: A Literature Review

  • Xiaofang Tong,
  • Herman W. Barkema,
  • Diego B. Nobrega,
  • Chuang Xu,
  • Bo Han,
  • Chenyibo Zhang,
  • Jingyue Yang,
  • Xiaoping Li and
  • Jian Gao

Bovine mastitis, a prevalent disease in dairy farms, exerts a profound negative influence on both the health and productivity of dairy cattle, leading to substantial economic losses for the dairy industry. The disease is associated with different bac...

  • Article
  • Open Access
1 Citations
3,659 Views
30 Pages

Many infants consume both human milk and infant formula (mixed-fed); however, few studies have investigated how mixed feeding affects the gut microbiome composition and metabolic profiles compared to exclusive breastfeeding or formula feeding. Herein...

  • Article
  • Open Access
2 Citations
2,013 Views
19 Pages

Elucidating the gene regulatory mechanisms underlying the gut–brain axis is critical for uncovering novel gut–brain interaction pathways and developing therapeutic strategies for gut bacteria-associated neurological disorders. Most studie...

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Microorganisms - ISSN 2076-2607