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Cells, Volume 14, Issue 24

December-2 2025 - 8 articles

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Articles (8)

  • Article
  • Open Access

Lack of Fas/FasL Does Not Protect from Latent Herpes Simplex 1 Infection but Decreases Virus-Induced Neurodegeneration

  • Magdalena Patrycy,
  • Agnieszka Kauc,
  • Martyna Janicka,
  • Aleksandra Osińska,
  • Andrzej Kowalczyk,
  • Katarzyna Skulska,
  • Małgorzata Antos-Bielska,
  • Marcin Chodkowski,
  • Kristina Eriksson and
  • Małgorzata Krzyżowska

5 December 2025

Many studies have shown an association between herpes simplex virus type 1 (HSV-1) infection and the development of neurodegeneration processes later in life, such as Alzheimer’s disease. The Fas/FasL death pathway plays an important role in th...

  • Article
  • Open Access

ucOCN Promotes Testosterone Synthesis via the PKA-MAPK/ERK-CREB Signaling Pathway in Porcine Leydig Cells

  • Guang Yang,
  • Han Liu,
  • Zhibao Yin,
  • Lihua Zhao,
  • Yanglin Chen,
  • Yiqing Li,
  • Linxin Cheng,
  • Junjun Ma,
  • Jinbo Yu and
  • Yu Zhang
  • + 2 authors

5 December 2025

Bone health might be closely associated with male fertility, yet the molecular pathways remain poorly characterized. We demonstrate that undercarboxylated osteocalcin (ucOCN), a bone-derived hormone, initiates a signaling cascade that stimulates test...

  • Review
  • Open Access

5 December 2025

Astrocytes play a pivotal role in shaping synaptic function and in learning, memory, and emotion. Recent studies show that perisynaptic astrocytic processes form structured interactions with pre- and postsynaptic elements, which extends synaptic dive...

  • Article
  • Open Access

Bcl3 Deficiency Leads to Hyperinflammation in Zebrafish

  • Chengjian Fan,
  • Nana Ai,
  • Wei Ge and
  • Vivien Ya-Fan Wang

5 December 2025

B-cell leukemia/lymphoma protein 3 (Bcl3), a member of the IκB family proteins, regulates the transcriptional activities of the NF-κB family of transcription factors. It is known that aberrant Bcl3 activities induce malignancies of both h...

  • Article
  • Open Access

Association Between Complete Blood Count and the Lipoxygenase Pathway in Hashimoto’s Thyroiditis

  • Karolina Wrońska,
  • Maciej Ziętek,
  • Tomasz Machałowski and
  • Małgorzata Szczuko

5 December 2025

Background: Hashimoto’s Thyroiditis (HT) is one of the most common autoimmune diseases worldwide, yet little is known about the role of lipid mediators in its pathogenesis. This study investigated whether there is a link between complete blood...

  • Review
  • Open Access

Microfluidic-Based Scratch Assays for Wound Healing Studies: A Systematic Review

  • Fernando A. Oliveira,
  • Nicole M. E. Valle,
  • Keithy F. da Silva,
  • Arielly H. Alves,
  • Marta C. S. Galanciak,
  • Gabriel M. Rosário,
  • Javier B. Mamani,
  • Mariana P. Nucci and
  • Lionel F. Gamarra

5 December 2025

Cell migration plays a central role in physiological processes such as wound healing, tissue regeneration, and immune responses, as well as in pathological conditions like chronic inflammation and tumor metastasis. Among the in vitro approaches to st...

  • Article
  • Open Access

5 December 2025

Lipid accumulation disrupts mitochondrial dynamics, leading to dysfunctional energy metabolism and increased oxidative stress. However, the relationship between mitochondrial dynamics and ovarian function in therapeutic contexts is still not fully el...

  • Review
  • Open Access

5 December 2025

Cervical ripening is a multifaceted process involving endocrine, inflammatory, and biomechanical signals that act on the cervical extracellular matrix. While previous reviews have focused on hormonal and immune mechanisms, the specific role of cervic...

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Cells - ISSN 2073-4409