Genetic and Cellular Basis of Autoimmune Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 754
Special Issue Editor
Interests: innate immunity; granulocytes; autoimmune diseases; skin inflammation; lipid mediators; Fcγ receptors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autoimmune diseases represent a significant and growing challenge to public health, affecting millions worldwide and contributing to considerable morbidity and mortality. In recent years, advances in genomic technologies and cellular biology have transformed our understanding of the intricate mechanisms underlying these diseases. High-throughput sequencing and genome-wide association studies (GWASs) have identified numerous genetic loci associated with autoimmune conditions, shedding light on the heritable components of these disorders. Concurrently, research into cellular pathways and immune responses has unveiled the roles of various immune cell types, including T cells, B cells, and innate immune cells, such as neutrophils and macrophages, in the pathogenesis of autoimmune diseases
This Special Issue aims to consolidate current knowledge on the genetic and cellular foundations of autoimmune diseases, highlighting recent discoveries and ongoing research. We invite contributions that explore the molecular mechanisms driving autoimmunity, the impact of genetic variations on immune function, and the interactions between genetic and environmental factors. By fostering a comprehensive understanding of these complex interactions, particularly the role of effector cells like neutrophils, we hope to pave the way for innovative therapeutic strategies and improved patient outcomes. In this Special Issue, we want to bring together leading experts in the field, showcasing diverse perspectives that underscore the importance of interdisciplinary collaboration in unraveling the complexities of autoimmune diseases.
Prof. Dr. Christian Sadik
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- autoimmune disease
- break of tolerance
- effector cells
- immunodysregulation
- risk genes
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