Recent Advances in Microfluidics and Organoids for Biomedical Applications
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 40
Special Issue Editor
Interests: magnetic nanoparticles; nanomedicine; therapy; diagnosis; theranostic; cancer; neurodegenerative diseases; magnetic hyperthermia; lab-on-a-chip; molecular imaging; organoid
Special Issue Information
Dear Colleagues,
Advances in microfluidics and organoids have revolutionized biomedicine by providing biomimetic models that overcome the limitations of traditional cell cultures and animal models. These technologies enable the precise control of microenvironments, cellular interactions, and dynamic physiological conditions, fostering breakthroughs in tissue engineering, pharmacology, toxicology, and regenerative medicine.
Microfluidics allows for controlled fluid dynamics, gradient formation, and real-time cellular monitoring, making it a key tool for studying biological barriers, drug delivery, and disease modeling. Meanwhile, organoids, derived from stem cells, offer 3D tissue architectures that better recapitulate developmental processes, disease progression, and therapeutic responses.
These platforms also play a crucial role in nanomedicine, supporting the development of nanoparticle-based therapies, biosensors, and advanced preclinical models.
This Special Issue welcomes original research, reviews, and perspectives on microfluidics and organoids, including the following:
- Development of microfluidic devices for tissue modeling, drug screening, and physiological microenvironment simulation;
- Innovations in organoid bioengineering, including enhanced tissue maturation, vascularization, and phenotypic stability;
- Microfluidic platforms for toxicity testing and safety assessment of new compounds;
- Advanced cell culture and differentiation strategies for creating more complex and functional organoids;
- Integration of biosensors and live imaging techniques for real-time monitoring of organoids and microfluidic systems;
- Computational modeling and artificial intelligence applied to the optimization of microfluidic and organoid systems;
- Applications in nanomedicine, including nanoparticle-based therapies, nanobiosensor development, and toxicity testing in biomimetic platforms.
We invite contributions that explore how these technologies are shaping the future of biomedicine, the pharmaceutical industry, and translational research.
Dr. Lionel Fernel Gamarra
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- microfluidics
- organoids
- biomimetic models
- organ-on-a-chip
- tissue engineering
- pharmacology
- biosensors
- computational modeling
- artificial intelligence
- nanomedicine
- personalized medicine
- bioprinting
- in silico
- induced pluripotent stem cells (iPSCs)
- mesenchymal and pluripotent stem cells
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