Table of Contents
Molecules, Volume 22, Issue 7 (July 2017)
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Cover Story (view full-size image) A new multifunctional composite, based on hydroxyapatite porous granules doped with selenite ions, [...] Read more. A new multifunctional composite, based on hydroxyapatite porous granules doped with selenite ions, and a biodegradable copolymer–bisphosphonate conjugate was developed. Biodegradable matrices were synthesized and characterized. A new amide bond was formed between the hydroxyl end groups of the synthesized carriers and an amine group of pamidronate (PAM). The dependence of the physico-chemical properties of the matrices on the kinetic release of PAM was observed. Therefore, the developed porous hydroxyapatite doped with selenite ions/biodegradable copolymer-PAM conjugate appears most attractive as a bone substitute material for cancer patients. View Paper here