The increasing prevalence of diabetes mellitus necessitates the development of advanced glucose-monitoring systems that are non-invasive, reliable, and capable of real-time analysis. Wearable electrochemical biosensors have emerged as promising tools...
Diabetes remains a great threat to human beings’ health and its world prevalence is projected to reach 9.9% by 2045. At present, the detection methods used are often invasive, cumbersome and time-consuming, thus increasing the burden on patient...
Thanks to their low-cost, portability, and sustainability, microfluidic thread-based analytical devices (μTADs) are emerging as an attractive analytical platform for wearable biosensing. While several μTADs, mainly based on colorimetric and ele...
Recent advances in microfluidics, microelectronics, and electrochemical sensing methods have steered the way for the development of novel and potential wearable biosensors for healthcare monitoring. Wearable bioelectronics has received tremendous att...
Wearable sweat biosensors for noninvasive monitoring of health parameters have attracted significant attention. Having these biosensors embedded in textile substrates can provide a convenient experience due to their soft and flexible nature that conf...
Sweat, a biofluid secreted naturally from the eccrine glands of the human body, is rich in several electrolytes, metabolites, biomolecules, and even xenobiotics that enter the body through other means. Recent studies indicate a high correlation betwe...
Wearable biosensors are attracting great interest thanks to their high potential for providing clinical-diagnostic information in real time, exploiting non-invasive sampling of biofluids. In this context, sweat has been demonstrated to contain physio...
Recently, biosensors have been used in an increasing number of different fields and disciplines due to their wide applicability, reproducibility, and selectivity. Three large disciplines in which this has become relevant has been the forensic, biomet...
Recently, several studies have been conducted on wearable biosensors. Despite being skin-adhesive and mountable diagnostic devices, flexible biosensor patches cannot truly be considered wearable biosensors if they need to be connected to external ins...
Cortisol is a key stress-related hormone whose accurate monitoring is essential for assessing physiological responses. Traditional detection methods are invasive and impractical for continuous use. This mini-review highlights recent advances in elect...
The expanding interest in digital biomarker analysis focused on non-invasive human bodily fluids, such as sweat, highlights the pressing need for easily manufactured and highly efficient soft lab-on-skin solutions. Here, we report, for the first time...
The incidence of diabetes is increasing at an alarming rate, and regular glucose monitoring is critical in order to manage diabetes. Currently, glucose in the body is measured by an invasive method of blood sugar testing. Blood glucose (BG) monitorin...
DNA nanoparticles have emerged as potent platforms for wearable and implantable biosensors owing to their molecular programmability, biocompatibility, and structural precision. This study delineates two principal categories of DNA-based sensing mater...
Smart textile-based wearable sweat sensors have recently received a lot of attention due to their potential for use in personal medical monitoring. They have a variety of desirable qualities, including low cost, easy implementation, stretchability, f...
A graphene oxide (GO)-based cortisol biosensor was developed to accurately detect cortisol concentrations from sweat samples at point-of-care (POC) sites. A reference electrode, counter electrode, and working electrode make up the biosensor, and the...
We report on the possibility of noninvasive diabetes monitoring through continuous analysis of sweat. The prediction of the blood glucose level in diabetic patients is possible on the basis of their sweat glucose content due to the positive correlati...
Metabolic diseases are increasing in relevance both in health and the economy in most countries. In this direction, if gold-standard technologies are based on blood analysis, non-invasive glucose monitoring is a relevant and great challenge that has...
Innovative biosensor technologies are revolutionizing cancer detection by offering non-invasive, sensitive, and rapid diagnostic tools, addressing the limitations of conventional screening. Non-invasive samples like breath, saliva, urine, and sweat,...
Wearable biosensors for the detection of analytes in sweat are an emerging and promising technology with important applications in monitoring a person’s physiological state. Sweat, being an easily accessible biofluid, shows great potential as a...
Wearable sensors and invasive devices have been studied extensively in recent years as the demand for real-time human healthcare applications and seamless human–machine interaction has risen exponentially. An explosion in sensor research throug...
This work demonstrates a novel electrochemical biosensor for the detection of chloride ion levels in ultra-low volumes (1–3 microliters) of passively expressed human sweat. We present here a hydration monitor that the pediatric, geriatric, and...
Biosensors have potentially revolutionized the biomedical field. Their portability, cost-effectiveness, and ease of operation have made the market for these biosensors to grow rapidly. Diabetes mellitus is the condition of having high glucose content...
Hypoxia, characterized by inadequate tissue oxygenation, may result in tissue damage and organ failure if not addressed. Current detection approaches frequently prove insufficient, depending on symptoms and rudimentary metrics such as tissue oxygenat...
Human physiological signals have an important role in the guidance of human health or exercise training and can usually be divided into physical signals (electrical signals, blood pressure, temperature, etc.) and chemical signals (saliva, blood, tear...
We report a paper-based self-powered sensor patch for prevention and management of exercise-induced hypoglycemia. The article describes the fabrication, in vitro, and in vivo characterization of the sensor for glucose monitoring in human sweat. This...
The objective of this study is to create a reliable predictive model for the electrochemical performance of self-powered biosensors that rely on urea-based biological energy sources. Specifically, this model focuses on the development of a human ener...
This article describes the design and the characterization of the ANTIGONE (ANalog To dIGital cONvErter) ASIC (Application Specific Integrated Circuit) built in AMS 0.35 m technology for low dc-current sensing. This energy-efficient ASIC was specific...
In this work, we investigated the effect of multi-walled carbon nanotubes (MWCNTs) and bio-graphene (bG) on the structure and activity of glucose oxidase (GOx), as well as on the performance of the respective electrochemical glucose biosensors. Vario...
Hyaluronic acid-based hydrogels are emerging as highly versatile materials for cost-effective biosensors, capable of sensitive chemical and biological detection. These hydrogels, functionalized with specific groups, exhibit sensitivity modulated by f...
The continued focus on improving the quality of human life has encouraged the development of increasingly efficient, durable, and cost-effective products in healthcare. Over the last decade, there has been substantial development in the field of tech...
Neurotransmitters are an important category of substances used inside the nervous system, whose detection with biosensors has been seriously addressed in the last decades. Dopamine, a neurotransmitter from the catecholamine family, was recently disco...
With the continuous advancement of contemporary medical technology, an increasing number of individuals are inclined towards self-monitoring their physiological health information, specifically focusing on monitoring blood glucose levels. However, as...
Dynamic glucose monitoring is important to reduce the risk of metabolic diseases such as diabetes. Wearable biosensors based on organic electrochemical transistors (OECTs) have been developed due to their excellent signal amplification capabilities a...
Wearable technology has advanced significantly, offering real-time monitoring of athletes’ physiological parameters and optimizing training and recovery strategies. Recent developments focus on biosensor devices capable of monitoring biochemica...
Owing to their potential to transform traditional medical diagnostics and health monitoring, wearable biosensors have become an alternative evolutionary technology in the field of medical care. However, it is still necessary to overcome some key tech...
Non-invasive continuous health monitoring has become feasible with the advancement of biosensors. While monitoring certain biomarkers such as heart rate or skin temperature are now at a certain maturity, monitoring molecular biomarkers is still chall...
The characteristics of a glucose sensor based on an ion-sensitive TiO2/Ti extended gate electrode field-effect transistor (EGFET) are reported. A glucose oxidase-containing silk fibroin membrane was immobilized on a TiO2/Ti surface as the bio-sensing...
Cortisol is a clinically validated stress biomarker that takes part in many physiological and psychological functions related to the body’s response to stress factors. In particular, it has emerged as a pivotal tool for understanding stress lev...
Recently, people are becoming more concerned about their physical health and putting forward higher requirements for an early and painless diagnosis of diseases. Traditional methods, such as surface plasmon resonance (SPR), enzyme-linked immunosorben...
Nanofiber technology is leading the revolution of wearable technology and provides a unique capability to fabricate smart textiles. With the novel fabrication technique of electrospinning, nanofibers can be fabricated and then manufactured into a dur...
This study endeavored to design and develop an innovative closed-loop diagnostic and therapeutic system with the following objectives: (a) the noninvasive detection of glucose concentration in sweat utilizing nanonengineered screen-printed biosensors...
Non-invasive healthcare technologies are an important part of research and development nowadays due to the low cost and convenience offered to both healthcare receivers and providers. This work overviews the recent advances in the field of non-invasi...
Enzymatic biofuel cells (EBFCs) have emerged as a transformative solution in the quest for sustainable energy, offering a biocatalyst-driven alternative for powering wearable and implantable self-powered biosensors. These systems harness renewable en...
Wearable biosensors have the potential for developing individualized health evaluation and detection systems owing to their ability to provide continuous real-time physiological data. Among various wearable biosensors, localized surface plasmon reson...
Noninvasive, continuous glucose detection can provide some insights into daily fluctuations in blood glucose levels, which can help us balance diet, exercise, and medication. Since current commercially available glucose sensors can barely provide rea...
The terminology used in electrochemical methods which are used to generate the measured signal in antioxidant/oxidant activity (AOA/OA) sensors is briefly considered. The review presents a hybrid version of electrochemical methods for the determinati...
In this paper, we present the results of a non-enzymatic electrochemical glucose biosensor based on TiO2. An anatase working electrode was synthesized using the spin coating technique with the polymeric precursor method and dispersed TiO2 nanoparticl...
Recent developments of point-of-care testing (POCT) and in vitro diagnostic medical devices have provided analytical capabilities and reliable diagnostic results for rapid access at or near the patient’s location. Nevertheless, the challenges o...
Rapid and accurate detection of changes in glucose (Glu) and hydrogen peroxide (H2O2) concentrations is essential for the predictive diagnosis of diseases. Electrochemical biosensors exhibiting high sensitivity, reliable selectivity, and rapid respon...
Co3O4-based materials have multiple applications in the field of materials, especially in sensor technology. In this work, Co3O4 nanoparticles were synthesized using a chemical method. The crystalline phase and crystal size were investigated by XRD,...
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