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Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges

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Sensors Technology Center, Ural State University of Economics, 62/45, 8 Marta/Narodnoi Voli St., Yekaterinburg 620144, Russia
2
Laboratory of sensor technologies in eco-, bio-, and pharmaceutical monitoring, Ural Federal University, Mira St. 19, 620002 Yekaterinburg, Russia
*
Author to whom correspondence should be addressed.
Chemosensors 2020, 8(4), 90; https://doi.org/10.3390/chemosensors8040090
Received: 15 August 2020 / Revised: 14 September 2020 / Accepted: 25 September 2020 / Published: 26 September 2020
(This article belongs to the Special Issue Electrochemical Sensors for Antioxidant/Oxidant Activity Monitoring)
The terminology used in electrochemical methods which are used to generate the measured signal in antioxidant/oxidant activity (AOA/OA) sensors is briefly considered. The review presents a hybrid version of electrochemical methods for the determination of AOA/OA. Invasive electrochemical methods/sensors for AOA/OA of blood/serum/plasma, and non-invasive ones for semen, sweat, saliva and skin determination are described. AOA/OA sensors application in health estimation, cosmetology, food and nutrients is presented. Attention is paid to widely described approaches and technologies used in chemical/biochemical sensors. It will be considered as base/prototypes for developing sensors of the kind for AOA/OA determination. Prospects for the development of wearable, written sensors and biosensors are considered. Miniature and wireless sensors will allow for the monitoring of the patient’s state, both at the bedside and far beyond the hospital. The development of wearable self-powered written and printed sensors is an important step towards personalized medicine. View Full-Text
Keywords: sensors; antioxidant/oxidant activity; oxidative stress; hybrid electrochemical methods; biofluids/tissue sensors; antioxidant/oxidant activity; oxidative stress; hybrid electrochemical methods; biofluids/tissue
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Brainina, K.Z.; Kazakov, Y.E. Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges. Chemosensors 2020, 8, 90.

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