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20 Results Found

  • Article
  • Open Access
1,258 Views
15 Pages

Serum Albumin, Globulin and Albumin–Globulin Ratios as Biomarkers of Clinical Outcomes in COVID-19 Pneumonia

  • Rauno Joks,
  • Tamar Smith-Norowitz,
  • Shawn Mathew,
  • Mansi R. Kothari and
  • Sairaman Nagarajan

22 June 2026

Objective: Low serum albumin has been linked to morbidity and mortality in critically ill patients, including those with COVID-19. Whether serum globulin levels and albumin/globulin ratios (AGRs) can serve as biomarkers in COVID-19 is less well-chara...

(This article belongs to the Section Disease Biomarkers)
  • Article
  • Open Access
1 Citations
840 Views
12 Pages

Common Serum Biomarkers and Combination Ratios in the Diagnosis of Periprosthetic Joint Infection Following Total Hip Arthroplasty

  • Jason M. Dayan,
  • Don H. Le,
  • Anzar Sarfraz,
  • Theodor Di Pauli von Treuheim,
  • Farouk Khury,
  • Sallie Yassin,
  • Vinay K. Aggarwal,
  • Ran Schwarzkopf and
  • Alan J. Dayan

Accurate preoperative diagnosis of periprosthetic joint infection (PJI) is difficult, complicating distinction between septic and aseptic failures. This study assessed the value of common serum biomarkers and three calculated ratios—albumin&nda...

(This article belongs to the Section Medical Microbiology)
  • Review
  • Open Access
13 Citations
3,156 Views
11 Pages

Accuracy of Albumin, Globulin, and Albumin–Globulin Ratio for Diagnosing Periprosthetic Joint Infection: A Systematic Review and Meta-Analysis

  • Hyonmin Choe,
  • Emi Kamono,
  • Koki Abe,
  • Yuta Hieda,
  • Hiroyuki Ike,
  • Ken Kumagai,
  • Naomi Kobayashi and
  • Yutaka Inaba

5 December 2023

Periprosthetic joint infection (PJI) is one of the most intractable orthopedic diseases, partly because of the difficulty in differentiating septic from aseptic conditions. We aimed to evaluate and consolidate the diagnostic accuracy of the quantitat...

(This article belongs to the Special Issue Clinical Advances in Hip and Knee Surgery)
  • Article
  • Open Access
23 Citations
5,765 Views
14 Pages

10 August 2023

Neutrophil-to-lymphocyte (NLR), monocyte-to-lymphocyte (MLR), and platelet-to-lymphocyte (PLR) ratios have been proposed as diagnostic and prognostic markers for neoplastic and inflammatory diseases in dogs and cats. The aim of this retrospective pre...

(This article belongs to the Special Issue Advances in Companion Animal Clinical Pathology)
  • Article
  • Open Access
1 Citations
1,466 Views
13 Pages

Evaluation of the Diagnostic Accuracy of Serum Albumin and Globulin in Pyogenic Spondylitis

  • Hideo Mitsui,
  • Hyonmin Choe,
  • Masashi Shimoda,
  • Hironori Yamane,
  • Yuta Hieda,
  • Koki Abe,
  • Yohei Ito,
  • Hiroyuki Ike,
  • Ken Kumagai and
  • Yutaka Inaba
  • + 1 author

25 August 2025

Background: Serum markers are commonly used to diagnose bone and joint infections; however, their accuracy for diagnosing pyogenic spondylitis remains unproven. This study aimed to validate the diagnostic accuracy of inflammatory, nutritional, and im...

(This article belongs to the Special Issue Clinical Advances in Orthopedic Infections)
  • Article
  • Open Access
67 Citations
7,286 Views
12 Pages

15 November 2019

Background: Malnutrition and inflammation are highly prevalent and tightly regulated with each other in chronic kidney disease (CKD) patients. Inflammation can lead to malnutrition in patients with sufficient nourishment, while malnutrition may also...

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
1 Citations
3,429 Views
12 Pages

Should We Always Perform Preoperative Chest Computed Tomography in Patients with cT1a Renal Cell Carcinoma?

  • Jae-Wook Chung,
  • Jun-Koo Kang,
  • Se Won Jang,
  • Eun Hye Lee,
  • So Young Chun,
  • Seock Hwan Choi,
  • Jun Nyung Lee,
  • Bum Soo Kim,
  • Hyun Tae Kim and
  • Yun-Sok Ha
  • + 5 authors

12 November 2022

No definitive criteria regarding the performance of preoperative chest computed tomography (CT) in patients with cT1a renal cell carcinoma (RCC) exists. We aimed to establish an objective standard for the optimal timing of preoperative chest CT in pa...

(This article belongs to the Special Issue Treatment Advancement in Localized and Metastatic Renal Cell Carcinoma)
  • Review
  • Open Access
28 Citations
3,382 Views
11 Pages

Prognostic Value of Albumin to Globulin Ratio in Non-Metastatic and Metastatic Prostate Cancer Patients: A Meta-Analysis and Systematic Review

  • Stefano Salciccia,
  • Marco Frisenda,
  • Giulio Bevilacqua,
  • Pietro Viscuso,
  • Paolo Casale,
  • Ettore De Berardinis,
  • Giovanni Battista Di Pierro,
  • Susanna Cattarino,
  • Gloria Giorgino and
  • Alessandro Gentilucci
  • + 4 authors

29 September 2022

The aim of our meta-analysis is to analyze data available in the literature regarding a possible prognostic value of the albumin to globulin ratio (AGR) in prostate cancer (PC) patients. We distinguished our analysis in terms of PC staging, histologi...

(This article belongs to the Special Issue Molecular Biomarkers in Cancer and Their Applications)
  • Article
  • Open Access
9 Citations
2,996 Views
10 Pages

11 October 2022

Objective: To assess the value of using the prognostic nutritional index (PNI) and serum albumin/globulin ratio (AGR) in predicting the overall survival (OS) of patients with penile cancer (PC) undergoing penectomy. Materials and methods: A retrospec...

(This article belongs to the Section Surgical Oncology)
  • Article
  • Open Access
9 Citations
3,264 Views
27 Pages

Comparative Prospective and Longitudinal Analysis on the Platelet-to-Lymphocyte, Neutrophil-to-Lymphocyte, and Albumin-to-Globulin Ratio in Patients with Non-Metastatic and Metastatic Prostate Cancer

  • Stefano Salciccia,
  • Marco Frisenda,
  • Giulio Bevilacqua,
  • Pietro Viscuso,
  • Paolo Casale,
  • Ettore De Berardinis,
  • Giovanni Battista Di Pierro,
  • Susanna Cattarino,
  • Gloria Giorgino and
  • Alessandro Gentilucci
  • + 11 authors

3 December 2022

Purpose: To prospectively evaluate the albumin/globulin ratio (AGR), neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR) diagnostic and prognostic predictive value in a stratified population of prostate cancer (PC) cases. Methods:...

(This article belongs to the Collection New Insights into Prostate Cancer Diagnosis and Treatment)
  • Article
  • Open Access
15 Citations
4,633 Views
11 Pages

Comparative Evaluation of Peripheral Blood Neutrophil to Lymphocyte Ratio, Serum Albumin to Globulin Ratio and Serum C-Reactive Protein to Albumin Ratio in Dogs with Inflammatory Protein-Losing Enteropathy and Healthy Dogs

  • Federica Cagnasso,
  • Antonio Borrelli,
  • Enrico Bottero,
  • Elena Benvenuti,
  • Riccardo Ferriani,
  • Veronica Marchetti,
  • Piero Ruggiero,
  • Barbara Bruno,
  • Cristiana Maurella and
  • Paola Gianella

30 January 2023

Few routinely available biomarkers are clinically useful in assessing dogs with inflammatory protein-losing enteropathy caused by immunosuppressive-responsive enteropathy (IRE-PLE). Only the neutrophil to lymphocyte ratio (NLR) has been studied, whil...

(This article belongs to the Special Issue Diseases of the Small and Large Intestine, Liver and Pancreas in Small Animals)
  • Article
  • Open Access
461 Views
15 Pages

The Involvement of the Omentum in Defensive Peritoneal Mechanisms: New Evidence from Dogs Naturally Infected with Leishmania infantum

  • Hélio Noberto de Araújo,
  • Telma de Sousa Lima,
  • Moacir Franco de Oliveira,
  • Radan Elvis Matias de Oliveira,
  • Francisco Antônio Félix Xavier,
  • Tiago Cunha Ferreira,
  • Daniel de Araújo Viana and
  • Diana Célia Sousa Nunes-Pinheiro

31 July 2026

The omentum is an important immune surveillance organ located in the abdominal cavity, especially noteworthy in diseases displaying tropism for the mononuclear phagocyte system, such as canine leishmaniosis (CanL). In this context, this study aimed t...

(This article belongs to the Special Issue Canine and Feline Leishmaniosis: Research Advances and Diagnostic Innovations)
  • Article
  • Open Access
2 Citations
590 Views
11 Pages

Prognostic Role of Nutritional and Inflammatory Indices in Predicting Adverse Clinical Outcomes in Unplanned Hospitalized Oncology Patients

  • Salih Karatlı,
  • Doğan Yazılıtaş,
  • Seher Kaya,
  • Engin Yasin Baraklı,
  • Selahattin Çelik and
  • Gökşen İnanç İmamoğlu

15 April 2026

Background: Unplanned hospitalizations in patients with cancer are associated with adverse outcomes, including intensive care unit (ICU) transfer and in-hospital mortality. This study aimed to evaluate the predictive role of the prognostic nutritiona...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
1,622 Views
12 Pages

Absolute Eosinophil Count and Albumin–Globulin Ratio as Predictors of Delayed Graft Function in Deceased Donor Kidney Transplant: A Retrospective Analysis

  • Anupam Choudhary,
  • A. V. B. Krishnakanth,
  • K. R. Surag,
  • Kasi Viswanath,
  • Abhijit Shah,
  • Sunil Pillai and
  • Padmaraj Hegde

Background: Delayed graft function (DGF) is a frequent early complication after deceased donor kidney transplantation (DDKT), leading to prolonged hospitalization, increased risk of acute rejection, and reduced graft survival. Reliable and easily mea...

  • Article
  • Open Access
1 Citations
1,868 Views
12 Pages

Biomarkers of Survival in Patients with Colorectal Liver Metastases Treated with Percutaneous Microwave Ablation

  • Jakub Franke,
  • Grzegorz Rosiak,
  • Krzysztof Milczarek,
  • Dariusz Konecki,
  • Emilia Wnuk and
  • Andrzej Cieszanowski

26 March 2025

Background/Objectives: To evaluate the prognostic value of easily obtainable biomarkers for patients undergoing percutaneous microwave ablation (MWA) for colorectal liver metastases (CLMs). Prior studies showed that simple biomarkers, such as the lym...

(This article belongs to the Special Issue The Advance of Biomarker-Driven Targeted Therapies in Cancer)
  • Article
  • Open Access
14 Citations
3,988 Views
14 Pages

Abilities of Pre-Treatment Inflammation Ratios as Classification or Prediction Models for Patients with Colorectal Cancer

  • Andra Ciocan,
  • Răzvan A. Ciocan,
  • Nadim Al Hajjar,
  • Claudia D. Gherman and
  • Sorana D. Bolboacă

Background: Systemic inflammatory status is known as an important factor of colorectal cancer prognosis. Our study aimed to evaluate the performances of inflammation biomarker ratios as classification models of seven outcomes in patients with colorec...

(This article belongs to the Special Issue Diagnosis and Management of Rectal Cancer)
  • Article
  • Open Access
15 Citations
4,715 Views
13 Pages

Interplay between Comprehensive Inflammation Indices and Redox Biomarkers in Testicular Germ-Cell Tumors

  • Uros Bumbasirevic,
  • Nebojsa Bojanic,
  • Tatjana Simic,
  • Bogomir Milojevic,
  • Marko Zivkovic,
  • Tijana Kosanovic,
  • Boris Kajmakovic,
  • Aleksandar Janicic,
  • Otas Durutovic and
  • Vesna Coric
  • + 3 authors

Sustained and dysregulated inflammation, concurrent tumor-induced immune suppression, and oxidative stress are profoundly involved in cancer initiation, presentation, and perpetuation. Within this prospective study, we simultaneously analyzed the pre...

(This article belongs to the Section Mechanisms of Diseases)
  • Article
  • Open Access
1,077 Views
14 Pages

Application and Modification of Nutritional Assessment Tools in Hematologic Malignancies

  • Xinying Chen,
  • Xin Zheng,
  • Chenan Liu,
  • Qibiao Shi,
  • Xiaoyue Liu,
  • Zhaoting Bu,
  • Hong Zhao,
  • Bing Yin,
  • Changhong Xu and
  • Hanping Shi

27 February 2026

Background: Hematologic malignancies pose a critical threat to global health, with their pathological progression intrinsically linked to metabolic dysregulation and nutrient imbalance. Malnutrition accelerates the trajectory of adverse outcomes whil...

(This article belongs to the Special Issue Nursing and Supportive Care for Cancer Survivors)
  • Article
  • Open Access
7 Citations
3,651 Views
15 Pages

24 November 2022

Clear cell renal cell carcinoma (ccRCC) accounts for more than 90% of all renal cancers. The five-year survival rate of early-stage (TNM 1) ccRCC reaches 96%, while the advanced-stage (TNM 4) is only 23%. Therefore, early screening of patients with r...

(This article belongs to the Topic Real-Time Monitoring for Improving Cancer Diagnosis and Prognosis)
  • Review
  • Open Access
5 Citations
4,799 Views
19 Pages

Significance of Biogenetic Markers in Giant Cell Tumor Differentiation and Prognosis: A Narrative Review

  • Muhammad Taqi,
  • Haseeb ul Rasool,
  • Mobeen Zaka Haider and
  • Munjed Al Muderis

Background: Giant cell tumor of bone (GCTB) is a locally aggressive tumor. It accounts for only 5% of all bony tumors. Early diagnosis, and follow-up for recurrence is often difficult due to a lack of biogenetic markers. Giant cells are multinucleate...

(This article belongs to the Special Issue Biomarkers: Diagnostic Indicators for Human Ailments)