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24 Results Found

  • Article
  • Open Access
6 Citations
2,274 Views
12 Pages

In Vitro Antiparasitic Activity of Propyl-Propane-Thiosulfinate (PTS) and Propyl-Propane-Thiosulfonate (PTSO) from Allium cepa against Eimeria acervulina Sporozoites

  • María Arántzazu Aguinaga-Casañas,
  • Nuria Mut-Salud,
  • Ana Falcón-Piñeiro,
  • Ángela Alcaraz-Martínez,
  • Enrique Guillamón and
  • Alberto Baños

Among the alternatives to control avian coccidiosis, alliaceous extracts stand out due to their functional properties. Despite this, most of the references are focused just on garlic. In this study, we analyze the in vitro effects of propyl-propane t...

  • Article
  • Open Access
6 Citations
3,243 Views
15 Pages

Allium-Derived Compound Propyl Propane Thiosulfonate (PTSO) Reduces Vibrio Populations and Increases Body Weight of European Seabass (Dicentrarchus labrax) Juveniles

  • Miguel Rabelo-Ruiz,
  • Juan Manuel Peralta-Sánchez,
  • Antonio Manuel Martín-Platero,
  • Ana J. Ruiz,
  • María del Mar Agraso,
  • Laura Bermúdez,
  • Juan José Ariza,
  • Alberto Baños,
  • Eva Valdivia and
  • Manuel Martínez-Bueno

The global demand for fish products is continuously increasing as the population grows, and aquaculture plays an important role in supplying this demand. However, industrial antibiotic misuse has contributed to the spread of antimicrobial resistance...

  • Article
  • Open Access
5 Citations
2,947 Views
26 Pages

Two-Generation Toxicity Study of the Antioxidant Compound Propyl-Propane Thiosulfonate (PTSO)

  • Antonio Cascajosa-Lira,
  • Remedios Guzmán-Guillén,
  • Silvia Pichardo,
  • Alberto Baños,
  • Jose M. de la Torre,
  • Nahum Ayala-Soldado,
  • M. Rosario Moyano-Salvago,
  • Isabel Ortiz-Jaraba,
  • Ana M. Cameán and
  • Angeles Jos

Propyl-propane thiosulfonate (PTSO), an antioxidant organosulfur compound present in the genus Allium, has become a potential natural additive for food and feed, as well as a possible biopesticide for pest control in plants. A toxicological assessmen...

  • Article
  • Open Access
5 Citations
2,853 Views
15 Pages

Analytical Platform for the Study of Metabolic Pathway of Propyl Propane Thiosulfonate (PTSO) from Allium spp.

  • María García-Nicolás,
  • Marta Pastor-Belda,
  • Natalia Campillo,
  • María Jesús Rodríguez-Sojo,
  • Antonio Jesús Ruiz-Malagón,
  • Laura Hidalgo-García,
  • Paloma Abad,
  • José Manuel de la Torre,
  • Enrique Guillamón and
  • Natalia Arroyo-Manzanares
  • + 3 authors

15 February 2023

The present work is focused on the development of an analytical platform to elucidate the metabolic pathway of PTSO from onion, an organosulfur compound well-known for its functional and technological properties and its potential application in anima...

  • Article
  • Open Access
1 Citations
1,201 Views
20 Pages

Modulation of Human Immune Cells by Propyl-Propane Thiosulfonate (PTSO) Inhibits Colorectal Tumor Progression in a Humanized Mouse Model

  • María Jesús Rodríguez-Sojo,
  • Luckman Gbati,
  • Jose Alberto Molina-Tijeras,
  • Ailec Ho-Plágaro,
  • Teresa Vezza,
  • Laura López-Escánez,
  • Carmen Griñán-Lisón,
  • Juan Antonio Marchal,
  • Alberto Baños and
  • Alba Rodríguez-Nogales
  • + 5 authors

18 September 2025

Background/Objectives: Colorectal cancer (CRC) remains a major global health challenge and current therapies are not always effective. In addition, certain immune cell populations, such as myeloid-derived suppressor cells (MDSCs), pose a significant...

  • Article
  • Open Access
1 Citations
2,527 Views
11 Pages

The Effect of Encapsulated Propyl Propane Thiosulfonate (PTSO) on Apparent Ileal Digestibility and Productive Performance in Broiler Chickens

  • Gonzalo Villar-Patiño,
  • María del Carmen Camacho-Rea,
  • Myrna Elena Olvera-García,
  • Arturo Soria-Soria,
  • Julio César Baltazar-Vázquez,
  • Gabriela Gómez-Verduzco,
  • Lourdes Solano,
  • Guillermo Téllez and
  • Aurora Hilda Ramírez-Pérez

22 March 2023

This study analyzed the effects of different dietary doses of encapsulated propyl propane thiosulfonate (Pe-PTSO) on the apparent ileal digestibility (AID) of nutrients and productive performance in broilers. A total of 100 one-day-old Cobb 500 were...

  • Article
  • Open Access
12 Citations
3,332 Views
16 Pages

Beneficial Shifts in the Gut Bacterial Community of Gilthead Seabream (Sparus aurata) Juveniles Supplemented with Allium-Derived Compound Propyl Propane Thiosulfonate (PTSO)

  • Miguel Rabelo-Ruiz,
  • Antonio M. Newman-Portela,
  • Juan Manuel Peralta-Sánchez,
  • Antonio Manuel Martín-Platero,
  • María del Mar Agraso,
  • Laura Bermúdez,
  • María Arántzazu Aguinaga,
  • Alberto Baños,
  • Mercedes Maqueda and
  • Manuel Martínez-Bueno
  • + 1 author

17 July 2022

This study analyzes the potential use of an Allium-derived compound, propyl propane thiosulfonate (PTSO), as a functional feed additive in aquaculture. Gilthead seabream (Sparus aurata) juveniles had their diet supplemented with this Allium-derived c...

  • Article
  • Open Access
23 Citations
5,866 Views
18 Pages

Allium-Derived Compound Propyl Propane Thiosulfonate (PTSO) Attenuates Metabolic Alterations in Mice Fed a High-Fat Diet through Its Anti-Inflammatory and Prebiotic Properties

  • Teresa Vezza,
  • José Garrido-Mesa,
  • Patricia Diez-Echave,
  • Laura Hidalgo-García,
  • Antonio J. Ruiz-Malagón,
  • Federico García,
  • Manuel Sánchez,
  • Marta Toral,
  • Miguel Romero and
  • María Elena Rodríguez-Cabezas
  • + 6 authors

28 July 2021

Background: Propyl propane thiosulfonate (PTSO) is an organosulfur compound from Allium spp. that has shown interesting antimicrobial properties and immunomodulatory effects in different experimental models. In this sense, our aim was to evaluate its...

  • Article
  • Open Access
1 Citations
2,768 Views
20 Pages

Effects of a Diet of Allium Extract on Growth, Biochemistry, Metabolism, and Gut Microbiota of Rabbits (Oryctolagus cuniculus)

  • Antonio Cascajosa-Lira,
  • Silvia Pichardo,
  • Alberto Baños,
  • María Arántzazu Aguinaga-Casañas,
  • Andrea Ricci,
  • Andrea Frabetti,
  • Andrea Barausse,
  • Angeles Jos and
  • Ana M. Cameán

9 December 2024

The rabbit farming industry is growing due to the rising demand for healthy, sustainable meat. Rabbit meat’s nutritional benefits and low environmental impact appeal to health-conscious consumers. To enhance economic sustainability, efforts foc...

  • Article
  • Open Access
14 Citations
3,607 Views
17 Pages

Antifungal Activity of Propyl-Propane-Thiosulfinate (PTS) and Propyl-Propane-Thiosulfonate (PTSO) from Allium cepa against Verticillium dahliae: In Vitro and in Planta Assays

  • Ana Falcón-Piñeiro,
  • Efrén Remesal,
  • Miguel Noguera,
  • Juan José Ariza,
  • Enrique Guillamón,
  • Alberto Baños and
  • Juan Antonio Navas-Cortes

8 September 2021

Verticillium wilt, caused by Verticillium dahliae, is the most devastating soil-borne fungal disease of olive trees worldwide. Currently, there is no effective measure available to control the pathogen in diseased plants in open field conditions. Sea...

  • Article
  • Open Access
15 Citations
3,326 Views
17 Pages

In Vitro Antitumor and Anti-Inflammatory Activities of Allium-Derived Compounds Propyl Propane Thiosulfonate (PTSO) and Propyl Propane Thiosulfinate (PTS)

  • Enrique Guillamón,
  • Nuria Mut-Salud,
  • María Jesús Rodríguez-Sojo,
  • Antonio Jesús Ruiz-Malagón,
  • Antonio Cuberos-Escobar,
  • Antonio Martínez-Férez,
  • Alba Rodríguez-Nogales,
  • Julio Gálvez and
  • Alberto Baños

11 March 2023

Increasing rates of cancer incidence and the side-effects of current chemotherapeutic treatments have led to the research on novel anticancer products based on dietary compounds. The use of Allium metabolites and extracts has been proposed to reduce...

  • Article
  • Open Access
19 Citations
3,536 Views
15 Pages

Antibacterial and Antiparasitic Activity of Propyl-Propane-Thiosulfinate (PTS) and Propyl-Propane-Thiosulfonate (PTSO) from Allium cepa against Gilthead Sea Bream Pathogens in In Vitro and In Vivo Studies

  • Jose F. Cabello-Gómez,
  • María Arántzazu Aguinaga-Casañas,
  • Ana Falcón-Piñeiro,
  • Elías González-Gragera,
  • Raquel Márquez-Martín,
  • María del Mar Agraso,
  • Laura Bermúdez,
  • Alberto Baños and
  • Manuel Martínez-Bueno

14 October 2022

The use of phytogenic extracts is considered a sustainable strategy for the prevention of fish diseases, including Alliaceae as a potential option due to their variety of bioactive compounds. In this study, we analyzed the antibacterial and antiparas...

  • Article
  • Open Access
27 Citations
5,817 Views
16 Pages

27 August 2019

Two garlic-derived compounds, Propyl Propane Thiosulfonate (PTS) and Propyl Propane Thiosulfinate (PTSO), were examined for their efficacy against mycotoxigenic Fusarium species (F. graminearum, F. langsethiae, F. verticillioides). The objectives wer...

  • Feature Paper
  • Article
  • Open Access
502 Views
18 Pages

3 February 2026

The hydroisomerization reaction of light alkanes was used to improve their octane value. Industrial light alkane feeds usually contain a certain amount of cycloalkanes and aromatics (known as hydrocarbon impurities). In this study, the influence of h...

  • Article
  • Open Access
8 Citations
3,543 Views
14 Pages

Garlic-Derived Metabolites Exert Antioxidant Activity, Modulate Gut Microbiota Composition and Limit Citrobacter rodentium Infection in Mice

  • Ling Zhu,
  • Audrey I. S. Andersen-Civil,
  • Josue L. Castro-Meija,
  • Dennis S. Nielsen,
  • Alexandra Blanchard,
  • John E. Olsen,
  • Stig M. Thamsborg and
  • Andrew R. Williams

15 October 2022

The garlic-derived compounds propyl propane thiosulfinate (PTS) and propyl propane thiosulfonate (PTSO) are metabolites with putative health benefits against intestinal inflammation that may be related to their antioxidant activity. However, the unde...

  • Article
  • Open Access
22 Citations
4,091 Views
14 Pages

Effects of Capsicum and Propyl-Propane Thiosulfonate on Rumen Fermentation, Digestion, and Milk Production and Composition in Dairy Cows

  • Andreas Foskolos,
  • Alfred Ferret,
  • Adriana Siurana,
  • Lorena Castillejos and
  • Sergio Calsamiglia

15 May 2020

Essential oils may affect rumen fermentation, nutrient digestion, and milk production and composition. The objective of this study was to test the effects of capsicum oleoresin (CAP) and propyl-propane thiosulfonate (PTSO) on rumen fermentation, tota...

  • Article
  • Open Access
39 Citations
5,789 Views
17 Pages

Antibacterial and Antifungal Activity of Propyl-Propane-Thiosulfinate and Propyl-Propane-Thiosulfonate, Two Organosulfur Compounds from Allium cepa: In Vitro Antimicrobial Effect via the Gas Phase

  • Antonio Sorlozano-Puerto,
  • Maria Albertuz-Crespo,
  • Isaac Lopez-Machado,
  • Lidia Gil-Martinez,
  • Juan Jose Ariza-Romero,
  • Alba Maroto-Tello,
  • Alberto Baños-Arjona and
  • Jose Gutierrez-Fernandez

29 December 2020

Propyl-propane thiosulfinate (PTS) and propyl-propane thiosulfonate (PTSO) are two volatile compounds derived from Allium cepa with a widely documented antimicrobial activity. The aim of this study was to evaluate their anti-candidiasis activity and...

  • Article
  • Open Access
2 Citations
4,171 Views
15 Pages

In Vitro Activity of Allium cepa Organosulfur Derivatives against Canine Multidrug-Resistant Strains of Staphylococcus spp. and Enterobacteriaceae

  • Alba Maroto-Tello,
  • Tania Ayllón,
  • María Arántzazu Aguinaga-Casañas,
  • Juan José Ariza,
  • Silvia Penelo,
  • Alberto Baños and
  • Gustavo Ortiz-Díez

9 January 2024

Background: The increase of multi-resistant bacteria, especially Staphylococcus spp. and Enterobacteriaceae, constitutes a challenge in veterinary medicine. The rapid growth of resistance is outpacing antibiotic discovery. Innovative strategies are n...

  • Article
  • Open Access
28 Citations
4,847 Views
14 Pages

Effect of Allium Extract Supplementation on Egg Quality, Productivity, and Intestinal Microbiota of Laying Hens

  • Paloma Abad,
  • Natalia Arroyo-Manzanares,
  • Juan J. Ariza,
  • Alberto Baños and
  • Ana M. García-Campaña

28 December 2020

The use of allium extract containing propyl propane thiosulfonate (PTSO) as hen feed supplement was evaluated to demonstrate its positive effect on egg production and intestinal microbiota modulation. The study was carried out on 90 laying hens whose...

  • Article
  • Open Access
3 Citations
2,019 Views
11 Pages

Control of Green Mold and Sour Rot in Mandarins by Postharvest Application of Natamycin and an Allium Extract

  • Elena Pérez Faggiani,
  • Gerónimo Fernandez,
  • Mariángeles Cocco,
  • Mauricio Sbres,
  • Oribe Blanco and
  • Joanna Lado

6 December 2024

The efficacy of natamycin (Fruitgard Nat 20) and Proallium (an extract of allium including propyl thiosulfinate oxide (PTSO)) against sour rot and green mold in mandarins was evaluated under controlled and commercial conditions. The study involved ar...

  • Article
  • Open Access
951 Views
34 Pages

This paper studies the distributed robust predefined-time sliding mode control (DRPSC) problem for high-order heterogeneous multi-agent systems under input saturation while considering external disturbances and model uncertainties. Firstly, a distrib...

  • Article
  • Open Access
3 Citations
2,194 Views
11 Pages

Antimicrobial Efficacy of Phyto-L, Thiosulfonate from Allium spp. Containing Supplement, against Escherichia Coli Strains from Rabbits

  • Francesco D’Amico,
  • Gaia Casalino,
  • Francesca Rita Dinardo,
  • Michele Schiavitto,
  • Antonio Camarda,
  • Diana Romito,
  • Antonella Bove and
  • Elena Circella

23 June 2023

Colibacillosis, caused by enteropathogenic Escherichia coli (EPEC), is one of the most common diseases in rabbit farms, resulting in economic losses due to mortality and decrease in production. Until recently, antimicrobials were used to both treat a...

  • Article
  • Open Access
7 Citations
3,761 Views
21 Pages

Biochemical and Gene Expression Analyses in Different Poplar Clones: The Selection Tools for Afforestation of Halomorphic Environments

  • Vladislava Galović,
  • Marko Kebert,
  • Boris M. Popović,
  • Branislav Kovačević,
  • Verica Vasić,
  • Mary Prathiba Joseph,
  • Saša Orlović and
  • László Szabados

18 May 2021

Halomorphic soils cover a significant area in the Vojvodina region and represent ecological and economic challenges for agricultural and forestry sectors. In this study, four economically important Serbian poplar clones were compared according to the...

  • Article
  • Open Access
28 Citations
4,787 Views
15 Pages

Effect of Alliaceae Extract Supplementation on Performance and Intestinal Microbiota of Growing-Finishing Pig

  • Cristian Jesús Sánchez,
  • Silvia Martínez-Miró,
  • Juan José Ariza,
  • Josefa Madrid,
  • Juan Orengo,
  • María Arántzazu Aguinaga,
  • Alberto Baños and
  • Fuensanta Hernández

2 September 2020

The aim of the present study was to ascertain whether an Allium spp. extract rich in organosulfur compounds, such as propyl thiosulfonate (PTSO), added to the feed of growing-finishing pigs at 5 g/kg enhances growth performance or affects the fecal m...