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1,433 Results Found

  • Review
  • Open Access
120 Citations
18,733 Views
17 Pages

27 October 2017

We conducted a meta-analysis to evaluate the effects of probiotics and prebiotics on the immune response to influenza vaccination in adults. We conducted a literature search of Pubmed, Embase, the Cochrane Library, the Cumulative Index to Nursing and...

  • Review
  • Open Access
116 Citations
14,040 Views
39 Pages

Fermentation is widely used in the processing of dairy, meat, and plant products. Due to the growing popularity of plant diets and the health benefits of consuming fermented products, there has been growing interest in the fermentation of plant produ...

  • Review
  • Open Access
366 Citations
34,208 Views
23 Pages

Effects and Mechanisms of Probiotics, Prebiotics, Synbiotics, and Postbiotics on Metabolic Diseases Targeting Gut Microbiota: A Narrative Review

  • Hang-Yu Li,
  • Dan-Dan Zhou,
  • Ren-You Gan,
  • Si-Yu Huang,
  • Cai-Ning Zhao,
  • Ao Shang,
  • Xiao-Yu Xu and
  • Hua-Bin Li

15 September 2021

Metabolic diseases are serious threats to public health and related to gut microbiota. Probiotics, prebiotics, synbiotics, and postbiotics (PPSP) are powerful regulators of gut microbiota, thus possessing prospects for preventing metabolic diseases....

  • Review
  • Open Access
90 Views
14 Pages

28 January 2026

Microbiota-derived indoles and short-chain fatty acids (SCFAs) modulate intestinal immunity via the aryl hydrocarbon receptor (AhR) and vitamin D receptor (VDR). This review proposes an operational AhR–VDR axis—three testable models (sequ...

  • Commentary
  • Open Access
52 Citations
11,124 Views
21 Pages

14 November 2013

Natural medicines are an attractive option for patients diagnosed with common and debilitating musculoskeletal diseases such as Osteoarthritis (OA) or Rheumatoid Arthritis (RA). The high rate of self-medication with natural products is due to (1) lac...

  • Article
  • Open Access
60 Citations
8,046 Views
16 Pages

Nosema ceranae is a microsporidian fungus that parasitizes the midgut epithelial cells of honey bees, Apis mellifera. Due to the role that midgut microorganisms play in bee health and immunity, food supplementation with prebiotics and probiotics may...

  • Review
  • Open Access
175 Citations
23,303 Views
26 Pages

7 July 2021

The brain–gut–microbiome axis is a bidirectional communication pathway between the gut microbiota and the central nervous system. The growing interest in the gut microbiota and mechanisms of its interaction with the brain has contributed to the consi...

  • Systematic Review
  • Open Access
51 Citations
11,644 Views
12 Pages

14 January 2022

The gut microbiota is a key factor in the correct development of the gastrointestinal immune system. Studies have found differences between the gut microbiota of newborns delivered by cesarean section compared to those vaginally delivered. Our object...

  • Review
  • Open Access
120 Citations
32,523 Views
16 Pages

Biological, social, and psychological practices greatly affect the dietary intake of people; as a result, health-related complexities occur. Functional food and supplements have become popular due to their nutraceutical benefits, which make different...

  • Review
  • Open Access
79 Citations
20,520 Views
28 Pages

Impact of the Gut Microbiota Balance on the Health–Disease Relationship: The Importance of Consuming Probiotics and Prebiotics

  • Laura-Berenice Olvera-Rosales,
  • Alma-Elizabeth Cruz-Guerrero,
  • Esther Ramírez-Moreno,
  • Aurora Quintero-Lira,
  • Elizabeth Contreras-López,
  • Judith Jaimez-Ordaz,
  • Araceli Castañeda-Ovando,
  • Javier Añorve-Morga,
  • Zuli-Guadalupe Calderón-Ramos and
  • Luis-Guillermo González-Olivares
  • + 1 author

2 June 2021

Gut microbiota is a group of microorganisms that are deposited throughout the entire gastrointestinal tract. Currently, thanks to genomic tools, studies of gut microbiota have pointed towards the understanding of the metabolism of important bacteria...

  • Systematic Review
  • Open Access
10 Citations
5,017 Views
13 Pages

The Efficacy of Probiotics, Prebiotics, and Synbiotics in Patients Who Have Undergone Abdominal Operation, in Terms of Bowel Function Post-Operatively: A Network Meta-Analysis

  • Orestis Ioannidis,
  • Christos Chatzakis,
  • Maria Tirta,
  • Elissavet Anestiadou,
  • Konstantinos Zapsalis,
  • Savvas Symeonidis,
  • Stefanos Bitsianis,
  • Efstathios Kotidis,
  • Manousos George Pramateftakis and
  • Stamatios Angelopoulos
  • + 1 author

20 June 2023

Background: Abdominal operations may lead to post-operative bowel dysfunction, while administration of probiotics, prebiotics and synbiotics may limit its manifestation. Τhe study aimed to assess the efficacy of probiotics, prebiotics and synbiotics...

  • Brief Report
  • Open Access
7 Citations
4,733 Views
9 Pages

Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study

  • Delia Colombo,
  • Corinna Rigoni,
  • Alessandra Cantù,
  • Antonello Carnevali,
  • Rossella Filippetti,
  • Tiziana Franco,
  • Alessandra Grassi,
  • Camilla Loi,
  • Annamaria Mazzotta and
  • Giovanni Damiani
  • + 5 authors

27 November 2023

The role of the skin–gut axis in atopic dermatitis (AD) remains a subject of debate, limiting non-pharmacological interventions such as probiotics and prebiotics. To improve understanding of their potential as a monotherapy for stable mild case...

  • Review
  • Open Access
110 Citations
12,656 Views
26 Pages

The Effects of Probiotics, Prebiotics and Synbiotics in Non-Alcoholic Fat Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH): A Systematic Review

  • Rodrigo Zamignan Carpi,
  • Sandra M. Barbalho,
  • Katia Portero Sloan,
  • Lucas Fornari Laurindo,
  • Heron Fernando Gonzaga,
  • Paulo Cesar Grippa,
  • Tereza L. Menegucci Zutin,
  • Raul J. S. Girio,
  • Cláudia Sampaio Fonseca Repetti and
  • Jesselina Francisco dos Santos Haber
  • + 4 authors

Modifications in the microbiota caused by environmental and genetic reasons can unbalance the intestinal homeostasis, deregulating the host’s metabolism and immune system, intensifying the risk factors for the development and aggravation of non...

  • Review
  • Open Access
47 Citations
19,772 Views
22 Pages

Exploring the Influence of Gut–Brain Axis Modulation on Cognitive Health: A Comprehensive Review of Prebiotics, Probiotics, and Symbiotics

  • Mónika Fekete,
  • Andrea Lehoczki,
  • Dávid Major,
  • Vince Fazekas-Pongor,
  • Tamás Csípő,
  • Stefano Tarantini,
  • Zoltán Csizmadia and
  • János Tamás Varga

10 March 2024

Recent research exploring the relationship between the gut and the brain suggests that the condition of the gut microbiota can influence cognitive health. A well-balanced gut microbiota may help reduce inflammation, which is linked to neurodegenerati...

  • Article
  • Open Access
28 Citations
4,716 Views
13 Pages

The Effects of Single or Combined Supplementation of Probiotics and Prebiotics on Growth Performance, Dietary Energetics, Carcass Traits, and Visceral Mass in Lambs Finished under Subtropical Climate Conditions

  • Alfredo Estrada-Angulo,
  • Octavio Zapata-Ramírez,
  • Beatriz I. Castro-Pérez,
  • Jesús D. Urías-Estrada,
  • Soila Gaxiola-Camacho,
  • Claudio Angulo-Montoya,
  • Francisco G. Ríos-Rincón,
  • Alberto Barreras,
  • Richard A. Zinn and
  • Alejandro Plascencia
  • + 2 authors

5 November 2021

The aim of this trial was to test the effects of the use of eubiotics (pro- and prebiotics) alone or in combination in the diet of lambs finished under subtropical climate conditions. For this purpose, 40 Pelibuey × Katahdin lambs (29.5 ± 4.8 kg init...

  • Review
  • Open Access
45 Citations
8,800 Views
15 Pages

28 September 2021

The dysbiosis of gut microbiota may cause many complications in patients with end-stage renal disease, which may be alleviated by probiotic, prebiotic, and synbiotic supplementation. The aim of this systematic review and meta-analysis was to assess t...

  • Article
  • Open Access
30 Citations
5,124 Views
25 Pages

In Vitro Selection of Probiotics, Prebiotics, and Antioxidants to Develop an Innovative Synbiotic (NatuREN G) and Testing Its Effect in Reducing Uremic Toxins in Fecal Batches from CKD Patients

  • Mirco Vacca,
  • Giuseppe Celano,
  • Marcello Salvatore Lenucci,
  • Sergio Fontana,
  • Flavia Maria la Forgia,
  • Fabio Minervini,
  • Aurelia Scarano,
  • Angelo Santino,
  • Giuseppe Dalfino and
  • Maria De Angelis
  • + 1 author

We aimed to develop an innovative synbiotic formulation for use in reducing dysbiosis, uremic toxins (e.g., p-cresol and indoxyl sulfate), and, consequently, the pathognomonic features of patients with chronic kidney disease (CKD). Twenty-five probio...

  • Review
  • Open Access
26 Citations
6,273 Views
13 Pages

16 October 2022

Although massive progress in discovering allergic rhinitis (AR) aetiology has been made in recent years, its prevalence is still rising and it significantly impacts patients’ lives. That is why further and non-conventional research elucidating...

  • Article
  • Open Access
10 Citations
4,434 Views
14 Pages

Independent and Combined Effects of Probiotics and Prebiotics as Supplements or Food-Rich Diets on a Propionic-Acid-Induced Rodent Model of Autism Spectrum Disorder

  • Sana Razhan M. Alsubaiei,
  • Hanan A. Alfawaz,
  • Abdullah Yaseen Almubarak,
  • Nouf Ahmed Alabdali,
  • Abir Ben Bacha and
  • Afaf El-Ansary

29 December 2022

The link between nutrition and autism spectrum disorder (ASD) as a neurodevelopmental condition, which is clinically presented as significant delays or deviations in interaction and communication, has provided a fresh point of view and signals that n...

  • Article
  • Open Access
6 Citations
5,010 Views
18 Pages

Effects of a Diet Containing Sources of Prebiotics and Probiotics and Modification of the Gut Microbiota on the Reduction of Body Fat

  • Paweł Jagielski,
  • Izabela Bolesławska,
  • Iwona Wybrańska,
  • Juliusz Przysławski and
  • Edyta Łuszczki

In 2022, according to the World Health Organization (WHO) report, overweight and obesity have reached epidemic proportions in the WHO European Region, affecting almost 60% of adults. Based on the assessment of BMI (Body Mass Index), a group of 56 wom...

  • Editorial
  • Open Access
14 Citations
3,522 Views
4 Pages

23 August 2023

This Special Issue, titled “Probiotics and Prebiotics in Cardiovascular Diseases”, encompasses two comprehensive review articles examining the potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset...

  • Review
  • Open Access
85 Citations
13,970 Views
14 Pages

21 February 2020

The review covers achievements and developments in the field of probiosis and prebiosis originating from sources other than dairy sources, mainly from plant material like cereals. The actual definitions of probiotic microorganisms, prebiotic, and pos...

  • Review
  • Open Access
32 Citations
5,820 Views
14 Pages

24 March 2020

There is an ever-increasing appreciation for our gut microbiota that plays a crucial role in the maintenance of health, as well as the development of disease. Probiotics are live bacteria that are consumed to increase the population of beneficial bac...

  • Review
  • Open Access
33 Citations
11,473 Views
17 Pages

15 July 2022

Honey bees and honey, have been the subject of study for decades due to their importance in improving health. At times, some of the probiotics may be transferred to the honey stored in the honeycomb. Consumers may benefit from consuming live-probioti...

  • Review
  • Open Access
80 Citations
24,509 Views
19 Pages

Probiotic, Prebiotic, and Brain Development

  • Tomás Cerdó,
  • Alicia Ruíz,
  • Antonio Suárez and
  • Cristina Campoy

14 November 2017

Recently, a number of studies have demonstrated the existence of a link between the emotional and cognitive centres of the brain and peripheral functions through the bi-directional interaction between the central nervous system and the enteric nervou...

  • Review
  • Open Access
45 Citations
9,889 Views
15 Pages

Prebiotics, Probiotics, and Postbiotics in the Prevention and Treatment of Anemia

  • Zuzanna Zakrzewska,
  • Aleksandra Zawartka,
  • Magdalena Schab,
  • Adrian Martyniak,
  • Szymon Skoczeń,
  • Przemysław J. Tomasik and
  • Andrzej Wędrychowicz

Iron deficiency anemia (IDA) is very common and affects approximately 1/3 of the world’s human population. There are strong research data that some probiotics, such as Lactobacillus acidophilus and Bifidobacterium longum improve iron absorption...

  • Article
  • Open Access
35 Citations
5,206 Views
16 Pages

Prebiotic, Probiotic, and Synbiotic Consumption Alter Behavioral Variables and Intestinal Permeability and Microbiota in BTBR Mice

  • Jodi E. Nettleton,
  • Teja Klancic,
  • Alana Schick,
  • Ashley C. Choo,
  • Ning Cheng,
  • Jane Shearer,
  • Stephanie L. Borgland,
  • Jong M. Rho and
  • Raylene A. Reimer

Given that prebiotics have been shown to improve gut microbiota composition, gastrointestinal symptoms and select behaviors in autism spectrum disorder (ASD), we hypothesized that prebiotic supplementation would improve sociability, communication, an...

  • Review
  • Open Access
84 Citations
33,424 Views
23 Pages

Health Benefits of Prebiotics, Probiotics, Synbiotics, and Postbiotics

  • Nasser Al-Habsi,
  • Maha Al-Khalili,
  • Syed Ariful Haque,
  • Moussa Elias,
  • Nada Al Olqi and
  • Tasnim Al Uraimi

19 November 2024

The trillions of microbes that constitute the human gut microbiome play a crucial role in digestive health, immune response regulation, and psychological wellness. Maintaining gut microbiota is essential as metabolic diseases are associated with it....

  • Article
  • Open Access
6 Citations
3,170 Views
16 Pages

Bigel Matrix Loaded with Probiotic Bacteria and Prebiotic Dietary Fibers from Berry Pomace Suitable for the Development of Probiotic Butter Spread Product

  • Laura Tamašauskaitė,
  • Vidmantė Minelgaitė,
  • Aušra Šipailienė,
  • Rimantė Vinauskienė,
  • Viktorija Eisinaitė and
  • Daiva Leskauskaitė

20 May 2024

This study presents a novel approach to developing a probiotic butter spread product. We evaluated the prebiotic activity of soluble dietary fibers extracted from cranberry and sea buckthorn berry pomace with different probiotic strains (Limosilactob...

  • Review
  • Open Access
117 Citations
15,269 Views
10 Pages

A Systematic Review of the Role of Prebiotics and Probiotics in Autism Spectrum Disorders

  • Qin Xiang Ng,
  • Wayren Loke,
  • Nandini Venkatanarayanan,
  • Donovan Yutong Lim,
  • Alex Yu Sen Soh and
  • Wee Song Yeo

Background: Autism spectrum disorder (ASD) is a complex developmental condition typically characterized by deficits in social and communicative behaviors as well as repetitive patterns of behaviors. Despite its prevalence (affecting 0.1% to 1.8% of t...

  • Systematic Review
  • Open Access
26 Citations
9,084 Views
13 Pages

21 November 2022

Prebiotic and probiotic supplementation and yogurt consumption (a probiotic food) alter gut microbial diversity, which may influence colorectal carcinogenesis. This systematic review evaluates the existing literature on the effect of these nutritiona...

  • Review
  • Open Access
179 Citations
19,239 Views
24 Pages

Prebiotics, Probiotics, Synbiotics, Paraprobiotics and Postbiotic Compounds in IBD

  • Adrian Martyniak,
  • Aleksandra Medyńska-Przęczek,
  • Andrzej Wędrychowicz,
  • Szymon Skoczeń and
  • Przemysław J. Tomasik

18 December 2021

The increasing incidence of inflammatory bowel diseases (IBD) and the increasing severity of the course of these diseases create the need for developing new methods of therapy. The gut microbiome is extensively studied as a factor influencing the dev...

  • Article
  • Open Access
5 Citations
3,052 Views
26 Pages

Synbiotics contain health-beneficial bacteria, i.e., probiotics and prebiotics selectively utilized by the probiotics. Herein, three probiotic strains, Leuconostoc lactis CCK940, L. lactis SBC001, and Weissella cibaria YRK005, and the oligosaccharide...

  • Review
  • Open Access
34 Citations
6,302 Views
16 Pages

Prebiotics and Probiotics: Therapeutic Tools for Nonalcoholic Fatty Liver Disease

  • Alejandra Mijangos-Trejo,
  • Natalia Nuño-Lambarri,
  • Varenka Barbero-Becerra,
  • Misael Uribe-Esquivel,
  • Paulina Vidal-Cevallos and
  • Norberto Chávez-Tapia

5 October 2023

Alterations in the gut–liver axis and changes in the gut microbiome are among the risk factors for the pathogenesis of non-alcoholic fatty liver disease (NAFLD). These patients show increased bacterial overgrowth in the small intestine and impa...

  • Article
  • Open Access
11 Citations
16,999 Views
16 Pages

1 October 2024

Background/Objectives: Prebiotics and probiotics have been reported to improve symptoms of irritable bowel syndrome (IBS). Nevertheless, the effects of prebiotics/probiotics can vary depending on the IBS subtypes. The purpose of this study was to inv...

  • Article
  • Open Access
13 Citations
3,766 Views
14 Pages

Prebiotic Effect of Maitake Extract on a Probiotic Consortium and Its Action after Microbial Fermentation on Colorectal Cell Lines

  • Alessandra De Giani,
  • Federica Bovio,
  • Matilde Emma Forcella,
  • Marina Lasagni,
  • Paola Fusi and
  • Patrizia Di Gennaro

21 October 2021

Maitake (Grifola frondosa) is a medicinal mushroom known for its peculiar biological activities due to the presence of functional components, including dietary fibers and glucans, that can improve human health through the modulation of the gut microb...

  • Article
  • Open Access
30 Citations
5,771 Views
21 Pages

Role of L. plantarum KX519413 as Probiotic and Acacia Gum as Prebiotic in Gastrointestinal Tract Strengthening

  • Honey Chandran Chundakkattumalayil,
  • Sreelekshmi Kumar,
  • Rakhie Narayanan and
  • Keerthi Thalakattil Raghavan

Probiotics, prebiotics, and synbiotics are potential mediators to maintaining healthy intestinal flora and have garnered an area of wide research in the past few years. The current study assesses the in vivo effects of probiotic (Lactobacillus planta...

  • Article
  • Open Access
72 Citations
5,719 Views
10 Pages

The Simultaneous Administration of a Probiotic or Prebiotic with Live Salmonella Vaccine Improves Growth Performance and Reduces Fecal Shedding of the Bacterium in Salmonella-Challenged Broilers

  • Nahed A. El-Shall,
  • Ashraf M. Awad,
  • Mohamed E. Abd El-Hack,
  • Mohammed A. E. Naiel,
  • Sarah I. Othman,
  • Ahmed A. Allam and
  • Mahmoud E. Sedeik

30 December 2019

Salmonellosis is one of the most important bacterial diseases in poultry, causing heavy economic losses, increased mortality and reduced production. The aim of this study was the comparative efficacy of a commercial probiotic and/or prebiotic with a...

  • Review
  • Open Access
151 Citations
23,704 Views
27 Pages

Probiotics, Prebiotics, and Synbiotics: Implications and Beneficial Effects against Irritable Bowel Syndrome

  • Elemer Simon,
  • Lavinia Florina Călinoiu,
  • Laura Mitrea and
  • Dan Cristian Vodnar

20 June 2021

Irritable bowel syndrome (IBS) is still a common functional gastrointestinal disease that presents chronic abdominal symptoms but with a pathophysiology that is not yet fully elucidated. Moreover, the use of the synergistic combination of prebiotics...

  • Review
  • Open Access
93 Citations
14,619 Views
16 Pages

30 January 2019

Studies of probiotics, fructan-type prebiotics, and synbiotics in patients with ulcerative colitis (UC) show significant heterogeneity in methodology and results. Here, we study the efficacy of such interventions and the reasons for the heterogeneity...

  • Editorial
  • Open Access
3 Citations
2,289 Views
3 Pages

The scope of this Special Issue is to highlight and expand our knowledge on the molecular mechanisms of prebiotics and probiotics, as well as to offer a broad overview of current advancements and future directions in this research field [...]

  • Review
  • Open Access
40 Citations
7,770 Views
18 Pages

11 April 2022

Interactions between insects and their microbiota affect insect behaviour and evolution. When specific microorganisms are provided as a dietary supplement, insect reproduction, food conversion and growth are enhanced and health is improved in cases o...

  • Feature Paper
  • Article
  • Open Access
6 Citations
5,190 Views
21 Pages

Modulation of Canine Gut Microbiota by Prebiotic and Probiotic Supplements: A Long-Term In Vitro Study Using a Novel Colonic Fermentation Model

  • Alessandro Gramenzi,
  • Luana Clerico,
  • Benedetta Belà,
  • Meri Di Leonardo,
  • Isa Fusaro and
  • Giulia Pignataro

20 November 2024

The gut microbiota plays a crucial role in dogs’ health, influencing immune function, digestion, and protection against pathogens. This study evaluates the effects of three canine dietary supplements—Microbiotal (prebiotic), Lactobacillus...

  • Systematic Review
  • Open Access
4 Citations
5,069 Views
27 Pages

Probiotic, Prebiotic, and Synbiotic Supplementation for the Prevention and Treatment of Acute Otitis Media: A Systematic Review and Meta-Analysis

  • Freiser Eceomo Cruz Mosquera,
  • Mayerli de la Rosa Caldas,
  • Anisbed Naranjo Rojas,
  • Claudia Lorena Perlaza and
  • Yamil Liscano

30 April 2025

Background and Aim: Probiotics, prebiotics, and synbiotics have been documented to modulate the microbiota, enhance immunity, and reduce antibiotic resistance, making them a promising alternative in the management of acute otitis media (AOM). Accordi...

  • Review
  • Open Access
45 Citations
9,799 Views
21 Pages

The Gut Microbiome in Schizophrenia and the Potential Benefits of Prebiotic and Probiotic Treatment

  • Jonathan C. W. Liu,
  • Ilona Gorbovskaya,
  • Margaret K. Hahn and
  • Daniel J. Müller

31 March 2021

The gut microbiome (GMB) plays an important role in developmental processes and has been implicated in the etiology of psychiatric disorders. However, the relationship between GMB and schizophrenia remains unclear. In this article, we review the exis...

  • Review
  • Open Access
239 Citations
46,229 Views
28 Pages

Obesity has become a global epidemic and a public health crisis in the Western World, experiencing a threefold increase in prevalence since 1975. High-caloric diets and sedentary lifestyles have been identified as significant contributors to this wid...

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