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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Vaccination and Public Health in the 21st Century

edited by

Evridiki Patelarou

Enkeleint A. Mechili

and

Athina E. Patelarou

submission deadline 20 Dec 2025 | 11 articles | Viewed by 21401 | Submission Open

Keywords: vaccines; public health; clinical vaccine research; immunization; health technology assessment; vaccine development

(This special issue belongs to the Section Vaccines and Public Health)

Nanotechnology-Based Vaccines for the Prevention of Infectious Diseases

edited by Wandi Zhu

submission deadline 20 Dec 2025 | Viewed by 447 | Submission Open

Keywords: infectious diseases; nanoparticle vaccines; nanovaccine delivery; immune responses; vaccine adjuvant; immune protection; mucosal immunity

Human Immune Responses to Infection and Vaccination

edited by

Alexander Batista-Duharte

and

Gabriel Cabrera

submission deadline 31 Dec 2025 | 11 articles | Viewed by 25692 | Submission Open

Keywords: vaccine immunogenicity; adjuvants; new generation of vaccines; vaccine development; immune regulation; translational vaccinology; system vaccinology; herd immunity; vaccine safety; correlates of protection

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Evaluation of Vaccine Efficacy, Safety and Immunogenicity Against Influenza, RSV and COVID-19

edited by

Roland Zahn

submission deadline 31 Dec 2025 | 7 articles | Viewed by 21402 | Submission Open

Keywords: influenza; respiratory syncytial virus (RSV); COVID-19; SARS-CoV-2; vaccines; immunogenicity; efficacy; safety; universal vaccine

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Health Technology Assessment of Vaccination: Strategies, Public Health and Values

edited by Maarten J. Postma, Jurjen Van der Schans and

Cornelis Boersma

submission deadline 31 Dec 2025 | 5 articles | Viewed by 13967 | Submission Open

Keywords: health technology assessment; population access vaccine studies; vaccination cost-effectiveness; vaccine hesitancy

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines for the Vulnerable Population

edited by

My Kieu Ha

submission deadline 31 Dec 2025 | 3 articles | Viewed by 12740 | Submission Open

Keywords: vaccines; vulnerable populations; infectious diseases; immunization

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines Against Poultry Viruses

edited by

Xiuli Feng

submission deadline 31 Dec 2025 | 2 articles | Viewed by 12339 | Submission Open

Keywords: poultry and waterfowl; pigeons; wild birds; viral diseases; immunosuppressive disease; respiratory syndrome disease; poultry tumor diseases; immunoenhancers and adjuvants; genetically engineered vaccines; biosafety management of clinical veterinarians; antiviral drugs

(This special issue belongs to the Section Veterinary Vaccines)

The Current Development of Glycoconjugate Vaccines for Infectious Diseases

edited by Fatme Mawas

submission deadline 31 Dec 2025 | 4 articles | Viewed by 10078 | Submission Open

Keywords: bacterial vaccines; polysaccharides; conjugate vaccines; carrier proteins

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Prevention of Human Papillomavirus (HPV) and Vaccination

edited by

Sara Boccalini

Paolo Bonanni

and

Angela Bechini

submission deadline 31 Dec 2025 | 4 articles | Viewed by 9849 | Submission Open

Keywords: HPV vaccination; screening; PAP test; HPV-DNA test; HPV vaccine coverage; vaccine hesitancy; promotion

(This special issue belongs to the Section Human Papillomavirus Vaccines)

SARS-CoV-2, Influenza and Other Respiratory Viruses: Preventive Measures Affecting the Determinants of Health and Disease

edited by

Marco Del Riccio

and

Saverio Caini

submission deadline 31 Dec 2025 | 6 articles | Viewed by 9734 | Submission Open

Keywords: respiratory; viruses; SARS-CoV-2; human influenza; respiratory syncytial virus; vaccines; vaccination strategies; disease burden

(This special issue belongs to the Section Epidemiology and Vaccination)

The Development of mRNA Vaccines

edited by Minghui Yang, Yuming Li and Bo Hu

submission deadline 31 Dec 2025 | 3 articles | Viewed by 8264 | Submission Open

Keywords: nanoparticle delivery system; mRNA vaccines; infectious disease; tumor immunity; adjuvant

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Recent Scientific Advances in Vaccines for Shigella

edited by Akamol Suvarnapunya, Kristen A Clarkson, Renee Laird and August Louis Bourgeois

submission deadline 31 Dec 2025 | 4 articles | Viewed by 7184 | Submission Open

Keywords: Shigella; vaccines; global health

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

HPV Vaccination and Primary HPV Screening

edited by

Antonio Di Lorenzo

and

Pasquale Stefanizzi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5423 | Submission Open

Keywords: sexually transmitted diseases; HPV vaccination; cervical cancer screening; vaccine hesitancy; vaccine safety; vaccine effectiveness

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Epidemiology of Diseases Preventable by Vaccination

edited by

Caterina Elisabetta Rizzo

Cristina Genovese

and

Roberto Venuto

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5348 | Submission Open

Keywords: vaccine safety and efficacy; vaccination strategies; epidemiological surveillance; vaccine equity; disease burden and impact

(This special issue belongs to the Section Epidemiology and Vaccination)

Strategies to Enhance Vaccine Uptake and Immunization Among Underserved Populations/Vulnerable Groups

edited by

Álvaro Francisco Lopes De Sousa

submission deadline 31 Dec 2025 | 2 articles | Viewed by 5275 | Submission Open

Keywords: vaccine uptake; vulnerable populations; health interventions; vaccine hesitancy; public health strategies; health education and equity

(This special issue belongs to the Section Vaccines and Public Health)

Vaccine and Vaccination in Veterinary Medicine

edited by

Diqiu Liu

and Wen Shi

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4964 | Submission Open

Keywords: veterinary vaccine; vaccine design; vaccine safety and efficacy; immune response; immunization

(This special issue belongs to the Section Veterinary Vaccines)

Cutting-Edge Cancer Vaccines Enhanced by Nanotechnology

edited by

Xiupeng Wang

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4256 | Submission Open

Keywords: cancer immunotherapy; nanotechnology; cancer vaccine; adjuvant; in situ cancer vaccine; personalized cancer vaccine; combination cancer therapy; nanoparticle

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

The Development of Vaccine Against Parasite Infection

edited by

Kathryn M. Jones

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4235 | Submission Open

Keywords: adaptive immune response; vaccine; adjuvant; protozoal; helminth; apicomplexan; delivery systems; epidemiology; needs assessment

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Innovative Technology in Vaccine Development: Advancing Immunization Strategies

edited by Aziz Chentoufi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3472 | Submission Open

Keywords: vaccine; mRNA; viral vectors; nanoparticle; structural vaccinology; artificial intelligence; immunization

Role of Human Papillomavirus Vaccines in Cervical and Vulvo-Vaginal Diseases

edited by

Ignacio Zapardiel

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3202 | Submission Open

Keywords: human papillomavirus; preinvasive lesions; vulvar disease; cervical intraepithelial neoplasia; vaginal neoplasia

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Vaccine Strategies for HPV-Related Cancers: 2nd Edition

edited by

Diane M. Harper

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3180 | Submission Open

Keywords: HPV vaccine uptake; single dose immunization; clinical unmasking; HPV-associated cancers

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Vaccination or Infection and the Role of T Cells—the Response to Cancer, Autoimmunity or Inflammatory Diseases

edited by Yuedan Wang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2769 | Submission Open

Keywords: T-cell biology; cancer immunotherapy; autoimmune diseases; inflammatory diseases; immune modulation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

African Swine Fever Virus Vaccine Development

edited by

Faming Miao

, Hong Jia and

Lian-Feng Li

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2721 | Submission Open

Keywords: African swine fever virus; infection and damage; immune response; vaccine

(This special issue belongs to the Section Veterinary Vaccines)

Protective Immunity and Adjuvant Vaccines

edited by

Chengli Zong

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2064 | Submission Open

Keywords: protective immunity; adjuvant vaccines; viral diseases; innate immune response; adaptive immune response; vaccine efficacy

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Viral Vector-Based Vaccines

edited by Marija Zaric, Hilary Whitworth and Arianna Marini

submission deadline 31 Dec 2025 | Viewed by 502 | Submission Open

Keywords: viral vectors; vaccines; immune response; vaccine platforms; vaccine development; vaccine production; vaccine delivery; vaccine safety; infectious disease; cancer vaccines; humoral immunity; cellular immunity; preclinical studies; clinical trials

Animal Virus Infection, Immunity and Vaccines: 2nd Edition

edited by

Hani Boshra

submission deadline 31 Dec 2025 | Viewed by 439 | Submission Open

Keywords: zoonotic and veterinary diseases; viruses; vaccinology; immunology

(This special issue belongs to the Section Veterinary Vaccines)

T and B Cell Responses to HIV and Tuberculosis Infections/Coinfection and Vaccinations

edited by

Guohua Yi

submission deadline 31 Dec 2025 | Viewed by 416 | Submission Open

Keywords: T cells; B cells; viral infection; vaccination; vaccine development; immunity; vaccine efficacy

(This special issue belongs to the Section HIV Vaccines)

The Development of Ebolavirus Vaccines and Immunotherapeutics

edited by Kyle L. O'Donnell

submission deadline 31 Dec 2025 | Viewed by 337 | Submission Open

Keywords: Ebola; immunotherapeutics; vaccine platforms; immunogenicity; animal studies

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Immune-Mediated Diseases Following Vaccination

edited by

Giampiero Girolomoni

submission deadline 31 Dec 2025 | Viewed by 243 | Submission Open

Keywords: immune-mediated diseases; autoimmune diseases; atopic dermatitis; asthma; rheumatic diseases; vasculitis

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Development of Broadly Protective Vaccines Against Respiratory Virus Infections

edited by

Noopur Bhatnagar

and Jerry W. Simecka

submission deadline 20 Jan 2026 | Viewed by 388 | Submission Open

Keywords: broadly protective vaccines; respiratory viruses; universal vaccines; cross-protective immunity; vaccine development; mucosal immunity; T-cell responses; broadly neutralizing antibodies; immunogenicity; vaccine efficacy

Maternal Vaccination and Vaccines

edited by

Gianluca Straface

submission deadline 31 Jan 2026 | 6 articles | Viewed by 33902 | Submission Open

Keywords: prenatal care; vaccination; vaccination hesitancy; Tdap vaccine; influenza vaccine; COVID-19 vaccine

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines and Vaccination: HIV, Hepatitis Viruses, and HPV

edited by

Ivan Schietroma

and

Sonia Moretti

submission deadline 31 Jan 2026 | 8 articles | Viewed by 26291 | Submission Open

Keywords: preventative vaccine; therapeutic vaccine; HIV; hepatitis A; hepatitis B; human papillomavirus; sexually transmitted infections; immunoprotection; vaccination; preventable diseases

Prevention of Human Papillomavirus and Vaccines Strategies

edited by

Rui Gil da Costa

submission deadline 31 Jan 2026 | 5 articles | Viewed by 25467 | Submission Open

Keywords: human papillomavirus; HPV vaccines; vaccination strategies; cervical cancer prevention; therapeutic vaccines

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Fish Disease Occurrence and Immune Prevention and Control

edited by

Yonghua Hu

Jianmin Ye

and Yang Zhou

submission deadline 31 Jan 2026 | 4 articles | Viewed by 19765 | Submission Open

Keywords: fish immunology; fish disease; pathogenesis; virulence factor; disease prevention and control; vaccine

(This special issue belongs to the Section Veterinary Vaccines)

Virus-Like Particle Vaccine Development

edited by

Jian Xu

submission deadline 31 Jan 2026 | 8 articles | Viewed by 19711 | Submission Open

Keywords: vaccine; virus-like particle; display; protein production; immunogenicity

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immunity to Influenza Viruses and Vaccines

edited by

Rongbao Gao

submission deadline 31 Jan 2026 | 7 articles | Viewed by 17299 | Submission Open

Keywords: avian influenza; etiology; antiviral immunity; serology; vaccine; pathogenesis

(This special issue belongs to the Section Influenza Virus Vaccines)

Innovations in Vaccine Technology

edited by

Rachel Stephenson

submission deadline 31 Jan 2026 | 8 articles | Viewed by 16765 | Submission Open

Keywords: inactivated vaccines; live-attenuated vaccines; messenger RNA (mRNA) vaccines; subunit; recombinant; polysaccharide and conjugate vaccines; toxoid vaccines; viral vector vaccines; personalized vaccines; antigen design; reverse vaccinology; lipid nanoparticles; cell-based vaccine production; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Next-Generation Vaccine and Immunotherapy

edited by

Takashi Imai

submission deadline 31 Jan 2026 | 4 articles | Viewed by 15836 | Submission Open

Keywords: next-generation vaccine; immunotherapy; pathogens; cancers

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Analysis of Vaccine-Induced Adaptive Immune Responses

edited by

Francesco Nicoli

and

Antonella Caputo

submission deadline 31 Jan 2026 | 5 articles | Viewed by 15617 | Submission Open

Keywords: RNA sequencing; flow cytometry; microscopy; T cells; B cells; antibodies; biochemistry; molecular biology; systems biology; epitope prediction

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Recent Scientific Development of Poliovirus Vaccines

edited by

Lester M. Shulman

submission deadline 31 Jan 2026 | 6 articles | Viewed by 12979 | Submission Open

Keywords: novel oral polio vaccines (nOPV); vaccine-derived poliovirus (VDPV); recombination; inactivated oral vaccine strains (sIPV); edible vaccines; non-infectious vaccine-like particles (VLPs); subdermal administration of fractional doses; adjuvants; edible vaccines; microarray patches

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Vaccine Development and Global Health

edited by

Anna Paczkowska

Karolina Hoffmann

and

Krzysztof Kus

submission deadline 31 Jan 2026 | 3 articles | Viewed by 12619 | Submission Open

Keywords: next-generation vaccines; clinical efficacy of vaccines; vaccine safety; treatment methods for civilization diseases; public health; prevention of civilization diseases

(This special issue belongs to the Section Vaccines and Public Health)

Advances in Vaccine Adjuvants

edited by Devyani Joshi and Sanjeev Kumar

submission deadline 31 Jan 2026 | 5 articles | Viewed by 6749 | Submission Open

Keywords: infectious diseases; cancer vaccines; mechanisms of adjuvants; novel adjuvants; delivery systems; particulate adjuvants; innate immune response; adaptive immune response

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Pandemic Influenza Vaccination

edited by Francisco Nogareda and Shoshanna Goldin

submission deadline 31 Jan 2026 | 5 articles | Viewed by 6601 | Submission Open

Keywords: pandemic influenza; vaccines; zoonotic influenza; influenza A/H5; preparedness; response

(This special issue belongs to the Section Influenza Virus Vaccines)

Respiratory Viruses and Antiviral Immunity

edited by

Andreu Comas-Garcia

Sofía Bernal-Silva

and

Maria Grazia Cusi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 6558 | Submission Open

Keywords: respiratory viruses; innate antiviral response; adaptative antiviral response; prevention; damage; viral clearance

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Effectiveness and Safety of Vaccines in Special Populations

edited by Arjan Harxhi and

Justyna Dominika Kowalska

submission deadline 31 Jan 2026 | 4 articles | Viewed by 6065 | Submission Open

Keywords: vaccines; special populations; HIV; pregnancy; migrants

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Immune Responses in Patients with Inflammatory Bowel Disease After Vaccination

edited by

Phil-Robin Tepasse

and Arne Bokemeyer

submission deadline 31 Jan 2026 | 2 articles | Viewed by 5080 | Submission Open

Keywords: inflammatory bowel disease; vaccination; opportunistic infections; immune response; immunomodulatory therapy

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Host Immunity and Vaccines for Respiratory Pathogens

edited by

Hanqing He

and

Yuxia Liang

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4838 | Submission Open

Keywords: vaccines; immunity; infectious disease; respiratory pathogens

Challenges to Developing New Vaccines and Improving Existing Platforms

edited by

S. Louise Cosby

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4490 | Submission Open

Keywords: infectious disease; cancer vaccines; humoral and cellular immunity; flaviviruses vaccines; inactivated and subunit vaccines; novel assays

Development of Novel Mucosal Vaccines: Advances in Technology and Delivery

edited by

Mohamed I. Husseiny El-Sayed

submission deadline 31 Jan 2026 | 1 articles | Viewed by 4460 | Submission Open

Keywords: oral vaccines; nasal vaccines; live attenuated vaccines; DNA vaccines; mRNA vaccines; viral vectors vaccine; nanoparticle delivery system; adjuvants; gene-based vaccine; microencapsulation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccine Design and Development

edited by

Vladimir Temchura

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4143 | Submission Open

Keywords: vaccine design; vaccine development; vaccinology; immunization; immune response; vaccine delivery; vaccine efficacy

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

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