Viral Vector-Based Vaccines
A special issue of Vaccines (ISSN 2076-393X).
Deadline for manuscript submissions: 31 December 2025 | Viewed by 26
Special Issue Editors
Interests: immunology; vaccines; infectious diseases; global health; viral hemorrhagic fevers; epidemiology
Interests: epidemiology; emerging infectious diseases; vaccines; viral hemorrhagic fevers; global health
Special Issue Information
Dear Colleagues,
Viral vector-based vaccines have made significant progress in recent times. They utilize a modified virus as a "vector" to deliver genetic instructions for specific proteins to human cells; the body's cells then use these instructions to produce the antigen, triggering an immune response. This approach mimics a natural infection, delivering a robust and long-lasting immune memory. They are engineered to be replication-competent or replication-deficient, triggering both local and systemic immunity.
The development and deployment of viral vector-based vaccines against infectious diseases, like those used in the COVID-19 pandemic or Ebola virus outbreaks, demonstrate the feasibility and effectiveness of this approach. Different viruses with different properties have been employed. They are continuously being engineered for improved safety, efficacy, and target specificity, allowing for the delivery of antigens to specific cells or tissues. Viral vector-based vaccines are in clinical trials for various diseases, showcasing their potential for broader applications. Research continues to explore the use of viral vectors for a wider range of vaccines against infectious diseases and cancer.
In this Special Issue, we welcome original research papers, comprehensive reviews, and methodological reports that examine the design, preclinical or clinical development, deployment, or post-licensure evaluation of viral vector-based solutions.
Dr. Marija Zaric
Dr. Hilary Whitworth
Dr. Arianna Marini
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- viral vectors
- vaccines
- immune response
- vaccine platforms
- vaccine development
- vaccine production
- vaccine delivery
- vaccine safety
- infectious disease
- cancer vaccines
- humoral immunity
- cellular immunity
- preclinical studies
- clinical trials
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