Innovative Technology in Vaccine Development: Advancing Immunization Strategies

A special issue of Vaccines (ISSN 2076-393X).

Deadline for manuscript submissions: 31 December 2025 | Viewed by 321

Special Issue Editor


E-Mail Website
Guest Editor
Laboratory of Cellular and Molecular Immunology, Gavin Herbert Eye Institute, School of Medicine, University of California Irvine, Irvine, CA 92697, USA
Interests: vaccines; HSV; coronavirus; T cell immunity; transplant immunology; autoimmunity

Special Issue Information

Dear Colleagues,

Recent advancements in innovative technologies have transformed vaccine development, allowing for faster, safer, and more effective immunization strategies. Traditional vaccine production methods, such as live-attenuated and inactivated vaccines, have been enhanced and, in some cases, replaced by cutting-edge approaches. For example, mRNA vaccine platforms—demonstrated by the rapid response during the COVID-19 pandemic—offer flexibility, scalability, and precision in antigen expression. Viral vector technologies, nanoparticle-based vaccines, and recombinant protein platforms have improved immunogenicity while ensuring safety. Advances in computational biology, artificial intelligence, and structural vaccinology have further streamlined antigen design and epitope prediction, accelerating vaccine development. Next-generation delivery systems, such as microneedle patches and lipid nanoparticles, have also enhanced vaccine stability and administration.

This Special Issue highlights the transformative role of these technologies in vaccine development and emphasizes their potential to shape the future of global public health. This Special Issue invites original research and review articles on preclinical and clinical advancements in cutting-edge technologies for next-generation vaccines to combat emerging infectious diseases. We also welcome innovative studies that identify novel vaccine targets through advanced computational biology, artificial intelligence, and structural vaccinology, provided they include in vitro and in vivo validation experiments.

Dr. Aziz A. Chentoufi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vaccine
  • mRNA
  • viral vectors
  • nanoparticle
  • structural vaccinology
  • artificial intelligence
  • immunization

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Published Papers

This special issue is now open for submission.
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