Nanotechnology-Based Vaccines for the Prevention of Infectious Diseases

A special issue of Vaccines (ISSN 2076-393X).

Deadline for manuscript submissions: 20 December 2025 | Viewed by 18

Special Issue Editor


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Guest Editor
Center for Inflammation, Immunity and Infection, Georgia State University, Atlanta, GA 30303, USA
Interests: various nanoparticle vaccines developed against respiratory viral infection; including protein nanoparticles; mRNA nanoparticles; virus-like particles; and extracellular vesicle-based nanoparticles; the development of vaccine formulations to induce protective mucosal immunity in the respiratory system; the mechanisms of vaccine formulations that modulate lung cellular immunity and ensure long-term protection

Special Issue Information

Dear Colleagues,

Potential epidemics and pandemics continue to pose significant challenges to global health. To address these challenges, innovative vaccine platforms and delivery strategies are essential for improving stability, delivery efficiency, immune responses, and protective efficacy. Nanotechnology is a transformative approach to vaccinology, offering enhanced stability, controlled release and delivery mechanisms, and targeted antigen presentation, leading to improved immune responses.
We invite the submission of contributions to this Special Issue that aim to advance the latest innovations in novel vaccine nanomaterials, formulations, delivery systems, immune modulation strategies, and their translational applications. This Special Issue will compile original research and review articles focusing on cutting-edge developments that address key challenges in infection prevention and demonstrate the potential to revolutionize immunization strategies. We welcome the submission of original research articles and reviews addressing the following topics:

  • Nanoparticle-based vaccine delivery systems (e.g., lipid nanoparticles, polymeric nanoparticles, virus-like particles, and extracellular vesicles);
  • Targeted antigen delivery and immune activation strategies;
  • Nanovaccines designed to induce mucosal immunity;
  • Applications of mRNA/DNA vaccines for infectious diseases;
  • The biocompatibility, safety, and toxicity of nanovaccines;
  • Clinical translation and regulatory considerations;
  • Nanovaccines for zoonotic and emerging pathogens.

We look forward to receiving your contributions.

Dr. Wandi Zhu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • infectious diseases
  • nanoparticle vaccines
  • nanovaccine delivery
  • immune responses
  • vaccine adjuvant
  • immune protection
  • mucosal immunity

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Published Papers

This special issue is now open for submission.
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