Development of Broadly Protective Vaccines Against Respiratory Virus Infections
A special issue of Vaccines (ISSN 2076-393X).
Deadline for manuscript submissions: 20 January 2026 | Viewed by 7
Special Issue Editors
Interests: viral pathogenesis; immune responses to viral vaccines; vaccine development; optimizing vaccine efficacy and safety; host–virus interactions
Interests: immunology; infectious diseases; drug evaluation; immunopathology; respiratory infections; mycoplasma
Special Issue Information
Dear Colleagues,
Respiratory virus infections, including those caused by influenza viruses, respiratory syncytial virues (RSVs), coronaviruses, and others, continue to pose substantial health burdens globally, thereby leading to significant morbidity and mortality. Traditional vaccines have provided varying degrees of success; however, their strain-specific protection and limited durability underscore the urgent need for broadly protective vaccines. These next-generation vaccines aim to elicit cross-reactive immune responses that can protect against multiple virus strains or species and potentially emerging variants.
This Special Issue seeks to highlight cutting-edge research and developments in the quest to create broadly protective vaccines against respiratory viruses. We invite the submission of original research articles and comprehensive reviews that address the following related topics:
- Strategies for designing broadly protective or universal vaccines targeting respiratory viruses.
- Development and optimization of novel vaccine platforms and adjuvants that enhance breadth and durability of protection.
- Characterization of cross-protective immune responses, including broadly neutralizing antibodies, T-cell responses, and mucosal immunity.
- Preclinical and clinical evaluations of vaccine efficacy against diverse respiratory virus strains or lineages.
- Special considerations in developing broadly protective vaccines for vulnerable populations, such as the elderly, immunocompromised individuals, and young children.
- Long-term safety, immunogenicity, and immune correlates of protection for broadly protective vaccine candidates.
We look forward to your valuable contributions that will help us advance toward more effective and universal solutions for preventing respiratory viral infections.
Dr. Noopur Bhatnagar
Prof. Dr. Jerry W. Simecka
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- broadly protective vaccines
- respiratory viruses
- universal vaccines
- cross-protective immunity
- vaccine development
- mucosal immunity
- T-cell responses
- broadly neutralizing antibodies
- immunogenicity
- vaccine efficacy
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