Latest Research Updates on Laparoscopy

A Special Issue of Life (ISSN 2075-1729) belonging to the section "Medical Research".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1527

Editors


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Guest Editor
1. Department of Surgery, “Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021 Bucharest, Romania
2. General Surgery Department, “Sf. Ioan” Clinical Emergency Hospital, 13 Vitan-Bârzeşti Road, 042122 Bucharest, Romania
Interests: laparoscopic surgery; minimally invasive surgery; bariatric surgery; hernia surgery; colorectal surgery; robotic surgery
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Surgery, “Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021 Bucharest, Romania
2. General Surgery Department, “Sf. Ioan” Clinical Emergency Hospital, 13 Vitan-Bârzeşti Road, 042122 Bucharest, Romania
Interests: laparoscopic surgery; colorectal surgery; coloproctology; hernia surgery; incisional hernia surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Minimally invasive technologies have reshaped modern healthcare, with laparoscopy playing a central role in advancing diagnostic precision and clinical decision-making. Ongoing improvements in imaging systems, optical engineering, and instrument design have significantly broadened the diagnostic applications of laparoscopy across diverse medical disciplines.

This Special Issue, “Latest Research Updates on Laparoscopy”, highlights innovative diagnostic methodologies, emerging visualization technologies, and new applications that improve early disease detection, intraoperative assessment, and patient stratification. We welcome submissions addressing experimental and clinical studies related to diagnostic laparoscopy, image-guided evaluation, artificial intelligence-assisted interpretation, ergonomic optimization, and comparative analyses of diagnostic performance.

Original research articles and systematic reviews that enhance evidence-based diagnostic practice and contribute to improved patient outcomes are encouraged. Through this Special Issue, we aim to foster interdisciplinary collaboration and showcase cutting-edge work that strengthens the role of laparoscopy as a safe, efficient, and transformative diagnostic tool.

You may choose our Joint Special Issue in Surgeries.

Prof. Dr. Niculae N. Iordache
Dr. Claudiu-Octavian Ungureanu
Guest Editors

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Keywords

  • laparoscopy
  • minimally invasive surgery
  • surgical innovation
  • imaging and navigation
  • artificial intelligence in surgery
  • surgical outcomes
  • clinical advancements

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Published Papers (2 papers)

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Research

19 pages, 1140 KB  
Article
Perioperative Hyperoxia and Early Pulmonary Epithelial and Glycocalyx-Related Biomarker Trajectories in Laparoscopic Surgery: A Prospective Randomized Study
by Sevda Guliyeva, Mert Canbaz, Kübra Vardar, Nükhet Sivrikoz, Özlem Turhan, Zerrin Sungur, Uğur Aksu and Mert Şentürk
Life 2026, 16(7), 1160; https://doi.org/10.3390/life16071160 - 14 Jul 2026
Viewed by 454
Abstract
Although perioperative oxygen therapy is a routine component of general anesthesia, its early biological consequences remain incompletely understood. This prospective randomized study evaluated whether perioperative oxygen concentration influences early biomarker responses in adults undergoing elective laparoscopic lower abdominal surgery. Patients received either normoxia [...] Read more.
Although perioperative oxygen therapy is a routine component of general anesthesia, its early biological consequences remain incompletely understood. This prospective randomized study evaluated whether perioperative oxygen concentration influences early biomarker responses in adults undergoing elective laparoscopic lower abdominal surgery. Patients received either normoxia (FiO2 0.35) or hyperoxia (FiO2 0.80) under standardized anesthesia. Clear physiological separation between groups was confirmed by arterial blood gas analysis. The primary biomarker finding was that circulating surfactant protein-A (SP-A) increased significantly in the normoxia group, whereas no comparable increase was observed under hyperoxia. Syndecan-1 and sialic acid showed descriptively similar directional patterns; however, these secondary biomarker findings were interpreted as exploratory and were not robust after Holm correction. By contrast, tumor necrosis factor-alpha (TNF-α) levels were higher postoperatively in the hyperoxia group, while ischemia-modified albumin (IMA) and total protein did not differ significantly between groups. These findings suggest that perioperative hyperoxia was associated with different early circulating biomarker trajectories across pulmonary epithelial and glycocalyx-related domains, without establishing pulmonary or endothelial protection. Further studies are needed to determine whether these early mechanistic findings translate into clinically meaningful outcomes. Full article
(This article belongs to the Special Issue Latest Research Updates on Laparoscopy)
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14 pages, 1187 KB  
Article
Minimally Invasive Versus Open Total Hysterectomy: From Practice Variability to a Decision Algorithm
by Nicoleta Alina Mareș, Alexandru Iordache, Niculae Iordache, Floris Cristian Stănculea, Ramon Vilallonga, Iuliana Ceaușu and Cristian Viorel Poalelungi
Life 2026, 16(5), 749; https://doi.org/10.3390/life16050749 - 1 May 2026
Cited by 1 | Viewed by 653
Abstract
Background: Hysterectomy is one of the most common gynecological surgical procedures for benign conditions. In clinical practice, the choice of approach is often influenced by technology availability, leading to selection bias rather than to a decision based on standardized clinical criteria. The study [...] Read more.
Background: Hysterectomy is one of the most common gynecological surgical procedures for benign conditions. In clinical practice, the choice of approach is often influenced by technology availability, leading to selection bias rather than to a decision based on standardized clinical criteria. The study aims to propose a standardized decision-making algorithm, based on objective clinical criteria, for selecting the surgical approach in total hysterectomy. Methods: This is a prospective, observational, analytical study conducted from November 2021 to June 2025, including a cohort of 332 patients who underwent total hysterectomy (LH, VH, AH) for benign gynecological pathology at two major centers in Bucharest. We proposed a decision algorithm based on the results obtained from predictive modelling and the quantified risk factors. Results: The choice of surgical approach is a critical factor in hematological stability, and the presence of comorbidities was associated with the type of approach (p < 0.001). Patients without comorbidities predominantly benefited from laparoscopy (48.85%), but as the anesthetic risk increased (ASA III and IV), the vaginal or abdominal routes were preferred. Conclusions: The convergence of these elements suggests that such a tool can standardize therapeutic decisions and improve the efficiency of interventions, offering a modern and predictable framework for gynecological surgery. Full article
(This article belongs to the Special Issue Latest Research Updates on Laparoscopy)
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