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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Bone Biology

edited by Barbara Peruzzi,

Martina Leopizzi

and Giulia Battafarano

submission deadline 30 Jul 2026 | 1 articles | Viewed by 748 | Submission Open

Keywords: bone tissue engineering; bone-targeted therapies; genetic bone diseases; bone mechanotransduction; bone cell pathophysiology; bone metabolism

(This special issue belongs to the Section Physiology and Pathology)

Migraine and Headache: From Clinical and Therapeutic Aspects

edited by

Jacob Genizi

submission deadline 30 Jul 2026 | Viewed by 263 | Submission Open

Keywords: migraine; headache; treatment; medication

(This special issue belongs to the Section Medical Research)

Advances and Applications of Sport Physiology: 2nd Edition

edited by

Sime Versic

and

Nikola Foretic

submission deadline 31 Jul 2026 | 5 articles | Viewed by 9245 | Submission Open

Keywords: sports medicine; strength and conditioning; diagnostics; sport injuries; performance analysis

(This special issue belongs to the Section Physiology and Pathology)

Sports Biomechanics, Injury, and Physiotherapy

edited by Manos Stefanakis

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1715 | Submission Open

Keywords: sports injuries; epidemiology; data-driven rehabilitation; objective assessment; injury prevention; return to play

(This special issue belongs to the Section Physiology and Pathology)

Microorganisms Engineering and Gene-Editing Methods

edited by

Jichao Wang

Guang Zhao

and Xia Zhao

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1639 | Submission Open

Keywords: microorganisms engineering; metabolic engineering; strain optimization; gene editing; CRISPR; recombination

(This special issue belongs to the Section Genetics and Genomics)

Vetinformatics-Driven Approaches to Animal Health and Disease

edited by

Jun-Mo Kim

and

Rajesh Kumar Pathak

submission deadline 31 Jul 2026 | 1 articles | Viewed by 961 | Submission Open

Keywords: animal health; livestock disease; vetinformatics; computational genomics; RNAseq; multi-omics; drug discovery; molecular docking; molecular dynamics simulation; vaccine design; one health

(This special issue belongs to the Section Animal Science)

Innovation in Fish Nutrition, Production Technology, and Welfare

edited by

Marian Burducea

, Liviu-Dan Miron and

Cristian-Alin Barbacariu

submission deadline 31 Jul 2026 | Viewed by 585 | Submission Open

Keywords: aquaculture; fish nutrition; fish welfare; water quality; fish disease; feed additives; rearing systems; modern feeding technologies; waste management

Multimodal AI for Genomic-Clinicopathologic Integration: From Preventive Screening to Precision Diagnosis

edited by Yen-Lin Chen

submission deadline 31 Jul 2026 | 1 articles | Viewed by 543 | Submission Open

Keywords: multimodal data integration; artificial intelligence in medicine; genomic and health data analysis; digital pathology and image analysis; predictive modeling and risk stratification; explainable machine learning (XAI)

(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)

Skin Care and Innovation from the Perspective of Molecular Dermatology

edited by

Ewa Markiewicz

Olusola Idowu

and

Jacek C. Szepietowski

submission deadline 31 Jul 2026 | Viewed by 484 | Submission Open

Keywords: molecular dermatology; personalised skincare; ageing; natural ingredients

(This special issue belongs to the Section Physiology and Pathology)

Non-Conventional Approaches in Modern Biological Analysis and Medical Diagnostics

edited by

Anna Baraniak

and

Paweł Rudnicki-Velasquez

submission deadline 31 Jul 2026 | Viewed by 265 | Submission Open

Keywords: biological samples; non-conventional analytical techniques; life science; diagnostics; proteins

Anti-Inflammatory and Natural Products

edited by

Chi-Su Yoon

submission deadline 31 Jul 2026 | Viewed by 128 | Submission Open

Keywords: anti-inflammation; macrophage; mechanism study; in vivo/in vitro model; natural products; natural products-derived compound

(This special issue belongs to the Section Pharmaceutical Science)

Precision Oncology Through Diagnostic Imaging and Theranostics

edited by

Wensi Tao

, Luyuan Li and Yu-Ping Yang

submission deadline 31 Jul 2026 | Viewed by 78 | Submission Open

Keywords: cancer imaging; molecular imaging; theranostics; nanomedicine; imaging biomarkers; precision oncology

(This special issue belongs to the Section Medical Research)

Genetic Regulation Mechanisms of Crop Salt–Alkali Tolerance

edited by

Zhenyuan Pan

submission deadline 31 Jul 2026 | Viewed by 72 | Submission Open

Keywords: crops; salt tolerance; genome; transcriptome; yield traits; genetic regulation mechanisms

(This special issue belongs to the Section Plant Science)

Compulsive Disorder: Understanding of the Pathophysiology and Therapeutic Implications

edited by

Donatella Marazziti

submission deadline 31 Jul 2026 | Viewed by 69 | Submission Open

Keywords: obsessive– compulsive disorder; compulsivity; cortico-striato-thalamo cortical circuits; cognitive inflexibility; glutamatergic modulation; neuroimmune mechanisms; neuromodulation; deep brain stimulation; precision psychiatry

(This special issue belongs to the Section Physiology and Pathology)

Molecular Mechanisms and Immune Regulation in Animal Diseases

edited by

Dagmara Winiarczyk

submission deadline 31 Jul 2026 | Viewed by 64 | Submission Open

Keywords: proteomics; animal diseases; mucosal immunity; biomarkers; host– pathogen interactions; immunoregulation; mass spectrometry; comparative medicine; veterinary proteomics; systems biology

(This special issue belongs to the Section Animal Science)

Black Holes in Atrial Fibrillation Therapy

edited by Roberto Cemin

submission deadline 31 Jul 2026 | Viewed by 64 | Submission Open

Keywords: atrial fibrillation; clinical guidelines; stroke prevention; oral anticoagulation; CHA2DS2-Va Score; catheter ablation; left atrial appendage closure; personalized medicine

(This special issue belongs to the Section Medical Research)

Building the Future of Veterinary Medicine: Foundational Data in Physiology and Pathology

edited by Bokyeong Ryu

submission deadline 31 Jul 2026 | Viewed by 59 | Submission Open

Keywords: veterinary physiology; veterinary pathology; veterinary database; multimodal evidence

(This special issue belongs to the Section Animal Science)

Mechanisms and Treatment of Eye and Vision Conditions

edited by Jeong-Min Hwang

submission deadline 31 Jul 2026 | Viewed by 58 | Submission Open

Keywords: mechanism; treatment; eye; vision

(This special issue belongs to the Section Medical Research)

Precision Medicine in Heart Failure: From Biomarkers to Targeted Therapies

edited by

Cristian Mornoş

submission deadline 31 Jul 2026 | Viewed by 53 | Submission Open

Keywords: heart failure; precision medicine; biomarkers; multi-omics; personalized therapy; cardiovascular imaging; genetic profiling; artificial intelligence; risk stratification; targeted therapies

(This special issue belongs to the Section Medical Research)

Novel Insights for Spinal Pain Management: From Physical Therapies to Ultrasound-Guided Procedures

edited by

Ke-Vin Chang

and

Vincenzo Ricci

submission deadline 31 Jul 2026 | Viewed by 53 | Submission Open

Keywords: spine; pain; physical therapies; rehabilitation; ultrasound; procedures

(This special issue belongs to the Section Medical Research)

Prevention and Control of Post-Radiotherapy Complications in Head and Neck Cancer

edited by Sung-Chan Shin

submission deadline 31 Jul 2026 | Viewed by 42 | Submission Open

Keywords: head and neck cancer; radiotherapy complications; post-radiation toxicity; radiation-induced injury; prevention and management; oral and pharyngeal toxicity; salivary gland dysfunction; osteoradionecrosis; functional rehabilitation; biomarkers and prediction models

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Plant Post-Transcriptional Regulation

edited by Haihui Fu

submission deadline 1 Aug 2026 | Viewed by 19 | Submission Open

Keywords: plant; post-transcriptional regulation; environmental adaptation; growth and development

(This special issue belongs to the Section Plant Science)

Skin Models and 3D Tissue: Fungal Infections and Antifungals

edited by Marisa Meloni,

Salvatore Prete

and Antonio Del Prete

submission deadline 5 Aug 2026 | Viewed by 56 | Submission Open

Keywords: mycosis; 3D tissue in vitro models; clinical and non clinical models; antifungal therapy

(This special issue belongs to the Section Microbiology)

Challenges and Innovations in Biomaterials for Tissue Engineering

edited by

Fei Fan

, Donny Hanjaya-Putra and Loan Bui

submission deadline 20 Aug 2026 | Viewed by 129 | Submission Open

Keywords: hydrogels; nanoparticles; extracellular matrix; microfluidics; bio-responsive; tissue engineering; regenerative medicine

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Recent Advances in Head and Neck Disorders

edited by

Cosmin Ioan Faur

and Maximilian Dindelegan

submission deadline 20 Aug 2026 | Viewed by 101 | Submission Open

Keywords: molecular pathology; biomedical technology; systems biology

(This special issue belongs to the Section Medical Research)

Spotlight on Cardiovascular Physiology and Related Diseases: Impact of Sex Differences

edited by

Helena Lenasi

submission deadline 21 Aug 2026 | Viewed by 60 | Submission Open

Keywords: cardiovascular physiology; microcirculation; endothelium; oxidative stress; sex differences; mathematical algorithms for biological signal analysis; metabolic diseases; hyperglycemia

(This special issue belongs to the Section Medical Research)

Oral Health and Systemic Conditions: From Biological Insights to Multidimensional Interventions

edited by

Gerson Aparecido Foratori-Junior

Carla Andreotti Damante

and

Nao Taniguchi (Nao Suzuki)

submission deadline 27 Aug 2026 | Viewed by 270 | Submission Open

Keywords: oral health ; periodontitis ; dental care ; tooth loss ; oral cancer ; facial esthetics ; salivary biomarkers ; systemic– oral health interactions ; non-invasive therapies ; clinical and epidemiological research

(This special issue belongs to the Section Medical Research)

Nutrition, Metabolism and Fitness: Exploring Dietary Effects on Exercise Physiology

edited by

Jesús Gustavo Ponce González

and

Daniel Velázquez Díaz

submission deadline 27 Aug 2026 | Viewed by 52 | Submission Open

Keywords: exercise physiology; sports nutrition; metabolic health; diet– exercise interactions; nutritional interventions; energy metabolism; performance and recovery

(This special issue belongs to the Section Physiology and Pathology)

Root–Soil–Microbe Interactions: Mechanisms and Management for Plant Performance and Ecosystem Function

edited by

Yuan Li

submission deadline 28 Aug 2026 | Viewed by 46 | Submission Open

Keywords: Root– soil– microbe interactions; Rhizosphere processes; Plant– microbe networks; Biogeochemical cycling; Microbiome-informed management

(This special issue belongs to the Section Plant Science)

The Age of Longevity: Unpacking Biogerontology and the Future of Human Life

edited by Paweł Kordowitzki

submission deadline 28 Aug 2026 | Viewed by 35 | Submission Open

Keywords: biogerontology; biological aging; longevity; healthspan extension; cellular senescence; epigenetic reprogramming; senolytics; gene editing; artificial intelligence in aging research

(This special issue belongs to the Section Physiology and Pathology)

Gut Health and Nutritional Strategies in Animals

edited by

Jian Ma

and Chunmei Du

submission deadline 28 Aug 2026 | Viewed by 19 | Submission Open

Keywords: microbiota; barrier function; immunity; precision feeding; additives

(This special issue belongs to the Section Animal Science)

Airway Management in Emergency and Intensive Care Medicine

edited by

Prashant Nasa

and Tonny V. Veenith

submission deadline 30 Aug 2026 | 3 articles | Viewed by 5881 | Submission Open

Keywords: airway management; critical care; laryngoscopy; intubation; intratracheal; emergency treatment

(This special issue belongs to the Section Medical Research)

Skin Diseases and Dermatologic Comorbidities

edited by Alessia Paganelli,

Emanuele Scala

and

Flavia Persechino

submission deadline 30 Aug 2026 | 3 articles | Viewed by 4666 | Submission Open

Keywords: skin diseases; dermatologic comorbidities; metabolic impairment; autoimmunity; cytokines; serum markers

(This special issue belongs to the Section Physiology and Pathology)

Molecular Muscle Adaptations Across the Lifespan

edited by S. Kyle Traivs and

Sime Versic

submission deadline 30 Aug 2026 | 1 articles | Viewed by 4602 | Submission Open

Keywords: muscle tissue; muscle physiology; molecular pathways; therapeutics

(This special issue belongs to the Section Physiology and Pathology)

Advances in Dialysis Pathology: Insights into Peritoneal and Hemodialysis Complications

edited by

Chien-Hung Lin

submission deadline 30 Aug 2026 | 1 articles | Viewed by 1050 | Submission Open

Keywords: peritoneal dialysis; hemodialysis; acute kidney injury (AKI); chronic kidney disease; pathology; complication

(This special issue belongs to the Section Physiology and Pathology)

Global Burden of Chronic Pain: Advances and Challenges in Pain Management and Clinical Practice

edited by Saba Javed and Billy Huh

submission deadline 30 Aug 2026 | 1 articles | Viewed by 474 | Submission Open

Keywords: chronic pain syndrome; cancer pain syndrome; neuromodulation; intrathecal pump; opioids; nerve blocks; joint injections

(This special issue belongs to the Section Medical Research)

Metabolic Eye Diseases: From Tomography to Clinical Prediction

edited by

Akio Oishi

and

Nilufer Yesilirmak

submission deadline 30 Aug 2026 | Viewed by 329 | Submission Open

Keywords: metabolic eye diseases; ophthalmic tomography and imaging biomarkers; diabetic retinopathy and systemic metabolic disorders; mitochondrial dysfunction and optic neuropathies; corneal metabolic diseases and ocular surface disorders; artificial intelligence in clinical prediction of eye diseases; metabolic pathways and retinal degeneration; translational research in metabolic ophthalmology

(This special issue belongs to the Section Physiology and Pathology)

Endocrine Mechanisms and Cellular Dynamics in Obesity: Insights and Innovations

edited by Manuel Gil Lozano and Marina Romaní-Pérez

submission deadline 30 Aug 2026 | Viewed by 292 | Submission Open

Keywords: gastrointestinal peptides; adipokines; food intake regulation; hypothalamus; orexigenic; anorexigenic; adipocytes; pancreatic islets; leptin; insulin

(This special issue belongs to the Section Physiology and Pathology)

Molecular Mechanisms and Therapeutic Effects of Drugs in Cancer—2nd Edition

edited by

Elżbieta Janina Płuciennik

Żaneta Kałuzińska-Kołat

and

Damian Kołat

submission deadline 31 Aug 2026 | 4 articles | Viewed by 9239 | Submission Open

Keywords: cancer; therapy; cancer drug; molecular mechanism; signaling pathways; targeted therapy; in silico drug response studies; innovative cancer treatment

(This special issue belongs to the Section Medical Research)

Advances in Biomedical Frontier Technologies and Disease Diagnosis

edited by

Alexey Yaremenko

submission deadline 31 Aug 2026 | 1 articles | Viewed by 3821 | Submission Open

Keywords: nanomedicine ; biomaterials ; gene therapy ; drug delivery ; bacteriotherapy ; nanobiotechnology ; hereditary diseases ; bioinformatics ; personalized medicine ; smart biomaterials

(This special issue belongs to the Section Medical Research)

Postharvest Softening, Flavor and Quality of Fruits: Molecular Mechanisms and Regulatory Approaches

edited by Qinggang Zhu and Yaxiu Xu

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1161 | Submission Open

Keywords: fruit softening; fruit quality; fruit flavor; molecular mechanisms; regulatory approaches

(This special issue belongs to the Section Plant Science)

Effects of Environmental Factors on Challenges of Plant Breeding: 2nd Edition

edited by

Katalin Magyar-Tábori

and

Nóra Mendler-Drienyovszki

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1094 | Submission Open

Keywords: plant breeding; winter hardiness; sowing time; adaptation to cold/frost; physiology of cold/frost tolerance; snow cover

(This special issue belongs to the Section Plant Science)

Conservation Ecology and Management of Mammalian Predators

edited by

Sándor Csányi

and

Miklós Gábor Heltai

submission deadline 31 Aug 2026 | Viewed by 809 | Submission Open

Keywords: mammalian predators; mesocarnivores; terrestrial predators; predator– prey interactions

(This special issue belongs to the Section Animal Science)

Innovations in Nuclear Medicine and Molecular Imaging

edited by

Christian Kühnel

and

Yiannis Parpottas

submission deadline 31 Aug 2026 | Viewed by 157 | Submission Open

Keywords: nuclear medicine; molecular imaging; PET; SPECT; radiopharmaceuticals; theranostics; quantitative imaging; artificial intelligence; dosimetry; precision medicine

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Progress in Rehabilitation Interventions for Heart Failure

edited by

João Morais

, Jhonatan Betancourt-Peña, Iago Portela and Mauricio Hernández-Carrillo

submission deadline 31 Aug 2026 | Viewed by 107 | Submission Open

Keywords: heart failure; rehabilitation; exercise; interdisciplinary; telerehabilitation

(This special issue belongs to the Section Medical Research)

Molecular Pathways Shaping Head and Neck Cancer Care

edited by

Albert Yoon-Kyu Han

submission deadline 31 Aug 2026 | Viewed by 81 | Submission Open

Keywords: head and neck cancer; molecular pathways; tumor microenvironment; precision oncology; translational research

(This special issue belongs to the Section Medical Research)

The Biochemistry of Venoms: Exploring Molecular Diversity, Structural Mechanisms, and Their Biotechnological Uses

edited by

Malson Neilson Lucena

and Ludovico Migliolo

submission deadline 31 Aug 2026 | Viewed by 78 | Submission Open

Keywords: biochemistry of venoms; venomics; diversity of toxins; mechanism of action; bioprospecting

(This special issue belongs to the Section Pharmaceutical Science)

Research on Glaucoma Diseases

edited by

Nicoleta Anton

submission deadline 31 Aug 2026 | Viewed by 69 | Submission Open

Keywords: glaucoma diseases; new technology; artificial intelligence in ophthalmology; gene therapy in glaucoma; new devices; artificial drainage systems

(This special issue belongs to the Section Medical Research)

Research Advances in Wetland Ecology

edited by

Yuxiang Yuan

and

Yunlong Yao

submission deadline 31 Aug 2026 | Viewed by 61 | Submission Open

Keywords: wetland; restoration; function; plant; algae; lake eutrophication; interspecific relationship; biogeochemical cycling; climate change

(This special issue belongs to the Section Diversity and Ecology)

Intensive Care Medicine: Current Concepts and Future Perspectives

edited by Shinichi Watanabe

submission deadline 31 Aug 2026 | Viewed by 56 | Submission Open

Keywords: intensive care; early mobilization; sepsis; mechanical ventilation; rehabilitation; artificial intelligence; PICS; multidisciplinary collaboration

(This special issue belongs to the Section Medical Research)

Displaying special issue 351-400 on page 8 of 10.

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