Advanced Research in Plant–Pathogen Interactions

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Plant Science".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1239

Special Issue Editors


E-Mail Website
Guest Editor
State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Ningbo University, Ningbo 315211, China
Interests: virus–host interaction; plant virus infection; epigenetics; plant immunity

E-Mail Website
Guest Editor Assistant
State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Ningbo University, Ningbo 315211, China
Interests: crop immunity and resistance; genetics and evolution; integrative omics; molecular plant pathology

Special Issue Information

Dear Colleagues,

Plant–pathogen interactions represent a central theme in plant biology, underpinning our understanding of plant health, crop productivity, and sustainable agriculture. Throughout evolution, plants have been continuously challenged by a broad spectrum of pathogens—including viruses, bacteria, fungi, oomycetes, and nematodes—and have consequently developed multilayered immune systems to perceive invasion and mount effective defense responses. In parallel, pathogens have evolved diverse strategies to evade, suppress, or exploit host immunity, resulting in a dynamic molecular arms race that shapes both plant defense and pathogen virulence.

This Special Issue, “Advanced Research in Plant–Pathogen Interactions,” is dedicated to showcasing recent advances that illuminate the molecular, cellular, and systemic mechanisms governing plant–pathogen interactions. We aim to bring together high-quality studies that provide mechanistic insights into host recognition of pathogens, immune signaling networks, pathogen effector functions, and host factors co-opted during infection. Particular emphasis is placed on innovative research that integrates cutting-edge technologies—such as genomics, transcriptomics, proteomics, metabolomics, structural biology, and advanced imaging—to resolve complex interaction networks with high spatial and temporal resolution.

The scope of this Special Issue spans both fundamental and applied research. Topics of interest include, but are not limited to, pattern- and effector-triggered immunity, RNA- and protein-based regulatory mechanisms, roles of small peptides and noncoding RNAs in plant defense, autophagy and other cellular quality-control pathways, pathogen adaptation and evolution, and translational strategies for enhancing crop disease resistance. By assembling contributions from diverse plant–pathogen systems and methodological perspectives, this Special Issue seeks to provide a comprehensive and forward-looking platform that will stimulate interdisciplinary dialogue.

We warmly invite researchers working in related fields to contribute latest findings to this Special Issue.

Dr. Tianye Zhang
Guest Editor

Dr. Bin Yong
Guest Editor Assistant

Manuscript Submission Information

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Keywords

  • plant-pathogen interaction
  • plant immunity
  • pathogen effectors
  • host defense mechanisms
  • autophagy
  • noncoding RNA
  • small peptides
  • molecular plant pathology
  • crop disease resistance

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Published Papers (2 papers)

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Research

25 pages, 4148 KB  
Article
Biocontrol Efficacy and Genomic Basis of Endophytic Bacteria Against Xanthomonas campestris pv. campestris in Cabbage
by Utku Sanver
Life 2026, 16(4), 647; https://doi.org/10.3390/life16040647 - 11 Apr 2026
Viewed by 564
Abstract
Xanthomonas campestris pv. campestris (Xcc) is the causal agent of black rot, one of the most destructive bacterial diseases on crucifer crops, resulting in yield losses of up to 90%. The aim of this study was to identify novel endophytic bacteria from cabbages [...] Read more.
Xanthomonas campestris pv. campestris (Xcc) is the causal agent of black rot, one of the most destructive bacterial diseases on crucifer crops, resulting in yield losses of up to 90%. The aim of this study was to identify novel endophytic bacteria from cabbages with potential biocontrol agents against Xcc. A total of sixty-five isolates were evaluated for plant growth-promoting characters and antagonistic activity, from which ten were selected for in planta assays and subsequently validated under field conditions. Pseudomonas synxantha BR25/2 consistently demonstrated the highest efficacy, reducing disease severity by 81.12% in in planta trials and 33.5% in field trials, thereby comparing to copper-based control measures. Additionally, Pseudomonas synxantha BR25/2 significantly enhanced yield parameters, including a 31.8% increase in head weight under field conditions. Whole-genome sequencing identified biosynthetic gene clusters, including siderophores, phenazines, and non-ribosomal peptide synthetases, notably a coronatine-like NRPS and a fengycin-like betalactone, suggesting an extensive antimicrobial potential of metabolites. This represents the first report of P. synxantha exhibiting control over Xcc. For commercial application, large-scale fermentation and encapsulation techniques are recommended to overcome shelf-life challenges, providing a sustainable microbial solution for crucifer production. Full article
(This article belongs to the Special Issue Advanced Research in Plant–Pathogen Interactions)
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22 pages, 3071 KB  
Article
Effects of Rootstock and Exogenous Plant Growth Regulators on Volatile Aroma Profiles and Terpenoid-Mediated Defense in Table Grape Fruit
by Yuyang Zhao, Tao Xu, Lingling Hu, Yanfei Guo, Zhihui Chen, Yueyan Wu and Zhongyi Yang
Life 2026, 16(4), 567; https://doi.org/10.3390/life16040567 - 31 Mar 2026
Viewed by 363
Abstract
The aroma quality of grape fruit is a crucial trait for table grapes, yet its relationship with plant disease resistance remains unclear. Using ‘Shine Muscat’ grapes as material, this study employed HS-SPME-GC-MS combined with odor activity value (OAV) and PLS-DA analysis to investigate [...] Read more.
The aroma quality of grape fruit is a crucial trait for table grapes, yet its relationship with plant disease resistance remains unclear. Using ‘Shine Muscat’ grapes as material, this study employed HS-SPME-GC-MS combined with odor activity value (OAV) and PLS-DA analysis to investigate the regulatory effects of different rootstocks and GA3/MeJA treatments on volatile aroma compounds. Linalool and α-terpineol were selected as representative compounds for antibacterial experiments and gene expression analysis of terpenoid synthesis. Results indicate that the Lot rootstock and 15.25 mg·L−1 GA3 treatment significantly promoted the accumulation of terpenoid aroma compounds. Linalool exhibited significant inhibitory effects on the mycelial growth of Colletotrichum fructicola and induced upregulation of DXS, TPS56, and TPS gene expression. This study reveals a potential link between aroma metabolism and defense responses, providing a theoretical basis for synergistic optimization of grape aroma quality improvement and disease-resistant cultivation. Full article
(This article belongs to the Special Issue Advanced Research in Plant–Pathogen Interactions)
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