Spotlight on Veterinary Pathology and Toxicology

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Animal Science".

Deadline for manuscript submissions: 25 September 2026 | Viewed by 1744

Editors


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Guest Editor
Internal Medicine Unit, Clinics Department, Faculty of Veterinary Medicine, Iași University of Life Sciences Ion Ionescu de la Brad, Iasi, Romania
Interests: veterinary medicine; internal medicine; toxicology; dermatology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Clinical Sciences I, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania
Interests: veterinary medicine; internal medicine; ultrasonography; therapeutics; toxicology

Special Issue Information

Dear Colleagues,

This Special Issue of Life titled “Spotlight on Veterinary Pathology and Toxicology” is dedicated to the study of animal diseases and their involvement in public health in the context of the concept of One Health and encompasses various aspects of pathology in domestic and wild animals and their involvement in public health, such as the following:

  • New challenges for veterinary pathology in the context of the SARS-CoV-2 pandemic; animals as potential reservoirs for SARS-CoV-2 and for other potential pandemics;
  • New challenges for veterinary pathology induced by climate change and the spread of tropical diseases in the northern hemisphere;
  • Diseases transmissible from animals to humans and from wild to domestic animals and means of prevention. Animal pandemics having major economic and social impacts: African swine fever, avian influenza, ruminant pest, etc.;
  • Diseases caused by industrial toxins, environmental pollution, and mycotoxins (current state of pathogenetic mechanisms, diagnosis, and means of prevention);
  • Epidemiology of non-communicable diseases concerning environmental pollution (allergies, cancer, and degenerative diseases);
  • Public health concerns related to antibiotic resistance and anti-parasitic resistance of bacteria, molds, and parasites involved in human and animal pathology.

This Special Issue also focuses on new developments in diagnosing and treating animal diseases and preventing their transmission to human beings or involvement in environmental contamination. Original manuscripts covering various aspects of veterinary pathology are requested. Papers reporting new solutions to common problems and new descriptions of lesser-recognized conditions are particularly welcome. In addition, we encourage papers detailing advanced diagnostic techniques, the use of microscopic anatomy in diagnosis, and computer modeling of pathological processes.

Prof. Dr. Gheorghe Solcan
Prof. Dr. Mario Darius Codreanu
Guest Editors

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Keywords

  • veterinary pathology
  • toxicology
  • advanced diagnostic techniques
  • pathogenesis
  • public health

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Published Papers (2 papers)

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Research

19 pages, 3899 KB  
Article
Ultrasonographic Gallbladder Findings and Bile Culture Results in Dogs with Extrahepatic Biliary Disorders: A Retrospective Exploratory Case Series
by Andrei Răzvan Codea, Alexandra Biriş, Mihaela Niculae, Romeo Popa, Daniela Mihaela Neagu, Cristian Popovici, Radu Lăcătuș and Mircea Mircean
Life 2026, 16(6), 904; https://doi.org/10.3390/life16060904 - 28 May 2026
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Abstract
Background: The role of bacterial infection in canine extrahepatic biliary disease remains inconsistently characterized. This retrospective case series evaluated associations between ultrasonographic gallbladder findings and bile culture results in dogs. Materials and Methods: Sixty-seven dogs were screened between March 2024 and December 2025, [...] Read more.
Background: The role of bacterial infection in canine extrahepatic biliary disease remains inconsistently characterized. This retrospective case series evaluated associations between ultrasonographic gallbladder findings and bile culture results in dogs. Materials and Methods: Sixty-seven dogs were screened between March 2024 and December 2025, of which 49 met inclusion criteria (clinical, biochemical, and ultrasonographic evidence of gallbladder disease) and underwent bile sampling by ultrasound-guided cholecystocentesis (n = 45) or intraoperative collection (n = 4). Samples were cultured aerobically and anaerobically; isolates identified by MALDI-TOF MS were further tested for in vitro antimicrobial susceptibility using Kirby–Bauer disk diffusion method. Results: Among the 49 included dogs, ultrasonography identified cholecystitis (75.5%), cholelithiasis (16.3%), and biliary mucocele (8.2%). Bile cultures were positive in 43/49 dogs (87.8%), yielding only aerobic bacteria. Escherichia coli (46.5%) and coagulase-positive Staphylococci (30.2%) were most frequently isolated organisms. However, these findings should be interpreted cautiously due to small subgroup sizes and the exploratory nature of the analysis. Conclusions: In this selected referral population, bacterial isolates were frequently recovered from bile samples, particularly in dogs with cholecystitis. Prospective studies involving larger populations are warranted to confirm these results, define the bacterial prevalence and clinical significance of bacterial colonization or infection, and further refine evidence-based diagnostic and treatment strategies for dogs with extrahepatic biliary disease. Full article
(This article belongs to the Special Issue Spotlight on Veterinary Pathology and Toxicology)
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9 pages, 1820 KB  
Article
Red Deer (Cervus elaphus) Fascioloidosis: From Liver Pathology to Regeneration
by Dean Konjević, Nikolina Škvorc, Miljenko Bujanić, Jan Čurlík, Anđelko Gašpar, Ivan-Conrado Šoštarić-Zuckermann and Andrea Gudan Kurilj
Life 2026, 16(3), 502; https://doi.org/10.3390/life16030502 - 19 Mar 2026
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Abstract
Fascioloidosis is a parasitic disease caused by allochthonous parasite Fascioloides magna. In Europe, three types of final hosts are recognised: definitive, aberrant, and dead end. Several countries have launched disease control programmes using medicated feed, with different drugs, to control F. magna [...] Read more.
Fascioloidosis is a parasitic disease caused by allochthonous parasite Fascioloides magna. In Europe, three types of final hosts are recognised: definitive, aberrant, and dead end. Several countries have launched disease control programmes using medicated feed, with different drugs, to control F. magna infections. In this study, we used corn treated with Albix® 10 in a total dose of 60 mg/kg of body weight for five consecutive days (12 mg/kg per day). Following successful treatment, a destroyed pseudocyst with different amounts of degrading material and decaying flukes was detected. A total of 136 livers was examined. The average number of pseudocysts per positive liver was seven (min. 1–max. 45), while the average number of adult flukes was 14.17 (2–70). On average, 1.34 juvenile flukes in the migratory phase were detected per infected liver. The average number of pseudocysts was 7.07 per liver in total. Degrading pseudocysts were either absent or present to a maximum of 120 per liver, with an average of 7.99 per liver. Some livers had multifocal to confluent nodules bulging from the liver parenchyma, which were up to 7 cm in diameter. Histologically, these areas showed disruption, containing bands of fibrous connective tissue, dividing parenchyma into pseudolobules of varying size and shape. These septa contained dark brown to black pigment (iron porphyrin), along with remnants of elliptical, operculated, mainly empty trematode eggs. Nodules were surrounded with fibrous tissue and disorganised hyperplastic hepatocytes arranged in irregular trabeculae supported by fibrous bands occasionally containing blood vessels. This study shows the potential of liver regeneration in the case of acute and chronic liver injury, as well as in cases of fatty liver disease. Full article
(This article belongs to the Special Issue Spotlight on Veterinary Pathology and Toxicology)
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