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Current Updates in Interventional Cardiology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 20 October 2026 | Viewed by 301

Special Issue Editor


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Guest Editor
Department of Cardiology, Medica Cor Hospital, 1713 Ruse, Bulgaria
Interests: coronary bifurcation lesions; complex percutaneous coronary intervention; coronary physiology
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Special Issue Information

Dear Colleagues,

Interventional cardiology is currently undergoing rapid and transformative progress. Procedures and technologies that were once limited to high-risk or select populations are now more precise, safer, and broadly applicable. Advances in coronary intervention—including physiology-guided decision-making, intravascular imaging, next‑generation drug‑eluting stents, and novel plaque modification techniques—have improved outcomes for complex lesions. Structural heart interventions such as TAVR, transcatheter mitral and tricuspid therapies, and valve‑in‑valve solutions continue to expand indications and refine device design and durability. The emergence of interventional electrophysiology, percutaneous mechanical circulatory support, and hybrid revascularization strategies further broaden therapeutic options for patients with advanced cardiac disease.

Moreover, the integration of AI, advanced imaging, and robotic platforms is enhancing procedural planning, intra-procedural guidance, and long‑term follow‑up. Personalized antithrombotic strategies and evolving peri‑procedural care protocols are helping to balance ischemic and bleeding risks.

For this Special Issue, we seek original research and reviews that present clinical advances in interventional cardiology—spanning diagnostics, devices, procedural techniques, and outcomes research—to help define the next frontier of minimally invasive cardiovascular care.

Dr. Dobrin Iotkov Vassilev
Guest Editor

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Keywords

  • interventional cardiology
  • innovation
  • intravascular imaging
  • complex PCI
  • structural heart interventions
  • personalized treatment strategy

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Published Papers (1 paper)

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Review

19 pages, 4029 KB  
Review
Coronary Computed Tomography Angiography for the Diagnosis and Revascularization Guidance of Coronary Bifurcation Lesions: A Contemporary Review
by Niya Mileva, Dobrin Vassilev, Panayot Panayotov, Slawomir Golebiewski, Gianluca Rigatelli and Robert J. Gil
J. Clin. Med. 2026, 15(12), 4565; https://doi.org/10.3390/jcm15124565 - 12 Jun 2026
Abstract
Background: Coronary bifurcation lesions represent one of the most technically demanding scenarios in coronary artery disease (CAD), associated with higher procedural complexity, restenosis, and periprocedural complications. Recent advances in coronary computed tomography angiography (CCTA) have markedly improved its ability to visualize complex [...] Read more.
Background: Coronary bifurcation lesions represent one of the most technically demanding scenarios in coronary artery disease (CAD), associated with higher procedural complexity, restenosis, and periprocedural complications. Recent advances in coronary computed tomography angiography (CCTA) have markedly improved its ability to visualize complex coronary anatomy, assess plaque morphology, and guide revascularization. Objectives: This review summarizes (1) technological advances in CCTA over the last decade, (2) its role in evaluating bifurcation stenosis, (3) assessment of plaque morphology and distribution, (4) quantification of bifurcation geometry, and (5) emerging evidence supporting its application in revascularization planning and guidance. Findings: Modern wide-detector and dual-source CT systems, iterative and deep-learning reconstruction algorithms, and photon-counting CT (PCCT) have significantly improved temporal and spatial resolution, reduced blooming artifacts, and lowered radiation dose. CCTA now reliably quantifies bifurcation stenosis and plaque distribution, characterizes high-risk plaque features, and accurately measures bifurcation angles. The integration of CT-derived fractional flow reserve (FFR-CT) and artificial intelligence (AI)-based plaque quantification further strengthens its diagnostic and prognostic performance. CCTA-derived bifurcation scores and 3D modelling support procedural strategy selection, stent sizing, and side-branch (SB) protection. Conclusions: CCTA has evolved into a comprehensive tool for non-invasive diagnosis, physiological assessment, and pre-procedural planning of bifurcation disease. With the advent of PCCT and AI-enhanced quantitative tools, CCTA is poised to become a central component of revascularization decision-making in complex coronary bifurcations. Full article
(This article belongs to the Special Issue Current Updates in Interventional Cardiology)
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