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Pancreatic Disorder, Pancreatitis, and Pancreatic Cancer: Interconnections, Clinical Challenges, and Therapeutic Advances

Special Issue Information

Dear Colleagues,

The pancreas is a complex organ, integral to both exocrine and endocrine systems, through its binary functions of digestive enzyme secretion and hormone synthesis. Despite its physiological importance, it remains vulnerable to a range of severe diseases, most notably acute and chronic pancreatitis, and pancreatic ductal adenocarcinoma (PDAC), the latter being one of the deadliest cancers worldwide. The insidious nature of pancreatic diseases, coupled with diagnostic complexities and the often-inflamed tumor microenvironment of pancreatic cancer, underscores an urgent need for innovative research. The overlapping pathophysiological pathways among these diseases, their complex clinical presentations, and the limited efficacy of current diagnostic and therapeutic strategies render pancreatic diseases a persistent global health concern.                          

This Special Issue invites high-quality original research and comprehensive reviews that delve into the molecular and clinical connections between pancreatitis, pancreatic cancer, and other pancreatic disorders. We welcome contributions that address novel insights into disease pathogenesis, innovative diagnostic tools for early detection, and advances in treatment modalities—from precision oncology approaches and targeted therapies to immunotherapies and surgical and neoadjuvant strategies aimed at overcoming resistance. Generating interdisciplinary knowledge, this collection aspires to spark progress in translational research and ultimately improve outcomes for patients affected by pancreatic disease.

Dr. Cristian George Ţieranu
Prof. Dr. Adrian Saftoiu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pancreatic disorder
  • pancreatitis
  • pancreatic cancer
  • translational research
  • diagnosis
  • treatment

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J. Clin. Med. - ISSN 2077-0383Creative Common CC BY license