Endocrine Malignancies: Current Surgical Therapeutic Approaches: 2nd Edition
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".
Deadline for manuscript submissions: 26 August 2025 | Viewed by 149
Special Issue Editors
Interests: general and colorectal surgery; laparoscopy; robotic surgery
Special Issues, Collections and Topics in MDPI journals
Interests: general and colorectal surgery; laparoscopy; robotic surgery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is my pleasure to invite you to contribute to the Special Issue entitled “Endocrine Malignancies: Current Surgical Therapeutic Approaches: 2nd Edition”. This is one new volume, we published 4 papers in the first volume. For more details, please visit: https://www.mdpi.com/journal/jcm/special_issues/E2J2571Q7H
Thyroid cancer (TC) is the most common endocrine neoplasia and is known to have a favorable prognosis. Nevertheless, differentiated thyroid cancer has the potential to be metastatic and poorly differentiated thyroid cancer can present at an advanced clinical stage upon initial observation. This makes it difficult to assess the clinical characteristics and treatment outcomes after surgical intervention, and these patients subsequently have a low survival rate. Various diagnostic and treatment methodologies are currently being trialed to overcome these limitations and efforts are being made to improve both the patient's prognosis and outcome.
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy and has a historically poor prognosis. Adjuvant therapy with mitotane, either alone or in combination with chemotherapy, is the standard of care treatment for ACC. Nevertheless, surgery remains the first line of curative treatment. Recently, several drugs targeting new pathways, such as insulin growth factor 2 (IGF2), beta-catenin pathway, and others, have entered clinical trials. Immunotherapy has also recently emerged as an important therapeutic option for several cancer models; however, the role of immunotherapy in the treatment cascade is not yet clear. Despite the recent advances in the development of novel treatment methods, ACC still has a poor prognosis.
This Special Issue encourages the submission of research articles which address how the pathophysiology of endocrine malignancy development drives both the current and novel emerging therapies that can be of benefit to patients, in addition to the refinement and advancement of surgical interventions. It is intended to present and discuss all the aspects of the currently available diagnostic and treatment methodologies, both surgical and non-surgical, of thyroid and adrenal malignancies via original research articles and reviews. For this Special Issue, we invite authors and researchers to publish original research and reviews highlighting the advancements in the diagnosis, prognosis, surgery, and therapeutics of endocrine malignancies, in particular, thyroid and adrenocortical cancer.
Potential topics may include, but are not limited to:
- Thyroid cancer diagnosis and differentiation.
- Clinical management and surgical treatment of TC patients.
- Parathyroid pathologies: clinical and surgical management.
- Adrenocortical cancer diagnosis: genetic, clinical, and radiological findings.
- New pathways, targeted drugs, and immunotherapy for ACC patients.
- Clinical management and surgical treatment of ACC patients.
- Multiple endocrine neoplasia, genetic correlations, and therapeutic approaches.
Dr. Mariarita Tarallo
Prof. Dr. Enrico Fiori
Dr. Marco Bononi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- endocrine malignancies
- thyroid cancer
- adrenocortical cancer
- parathyroid
- men
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