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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Carotid Artery Disease: Current Hurdles and Future Perspectives
edited by Andrej Udelnow
submission deadline 20 Aug 2026 | 1 articles | Viewed by 650
Keywords: carotid artery disease; carotid stenosis; endovascular technique; CEUS; elastography; high resolution CTA; atherosclerotic diseases; inflammatory diseases
(This special issue belongs to the Section Vascular Medicine)
Exploring Female Infertility: Advances, Challenges, and Emerging Solutions
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 645
Keywords: infertility; female infertility; in vitro fertilization; PCOS; assisted reproductive technology
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 570
Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advances in Orthopedic Infections: 2nd Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 371
Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management
(This special issue belongs to the Section Orthopedics)
State of the Art in Bladder Cancer: Diagnostics and Treatment Strategies
edited by
submission deadline 20 Aug 2026 | Viewed by 368
Keywords: bladder cancer; photodynamic diagnosis (PDD); bladder-sparing strategies; robotic-assisted surgery; single-port robotic cystectomy; older patients; immunotherapy; intravesical therapy; bladder preservation; minimally invasive urology; advanced bladder cancer; diagnostic innovation
(This special issue belongs to the Section Nephrology & Urology)
Optimizing Rehabilitation in Kidney Disease
edited by Henry H. L. Wu and Rajkumar Chinnadurai
submission deadline 20 Aug 2026 | Viewed by 341
Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning
(This special issue belongs to the Section Clinical Rehabilitation)
Integrated Ozone Therapy and Physical Rehabilitation for Musculoskeletal Disorders: A Comprehensive Approach submission deadline 20 Aug 2026 | Viewed by 336
Keywords: ozone therapy; physical rehabilitation; musculoskeletal disorders; integrative medicine; rehabilitation therapy; regenerative medicine; clinical outcomes
(This special issue belongs to the Section Clinical Rehabilitation)
Updates on Embolization and Embolotherapy for Benign Prostatic Hyperplasia and Men’s Health
edited by Sandeep L. Bagla, Ari J. Isaacson and Abin Sajan
submission deadline 20 Aug 2026 | Viewed by 330
Keywords: benign prostatic hyperplasia; prostatic artery embolization; men’s health; lower urinary tract symptoms; embolization therapy; radiation safety; prostate cancer and radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances and Perspectives in Neuro-Oncology
edited by Mariko Sato and
submission deadline 20 Aug 2026 | Viewed by 330
Keywords: neuro-oncology; diagnosis; treatment; minimally invasive surgery; skull base surgery; brain tumor; radiosurgery; neuro endoscopy
(This special issue belongs to the Section Clinical Neurology)
Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges
edited by Vasiliki Gkalea and Despina Fotiou
submission deadline 20 Aug 2026 | Viewed by 324
Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS
(This special issue belongs to the Section Hematology)
Personalised and Precision Pharmacotherapy: Data-Driven Therapeutic Optimisation in Real-World Clinical Practice submission deadline 20 Aug 2026 | Viewed by 305
Keywords: precision pharmacotherapy; personalised medicine ; pharmacokinetics and pharmacodynamics ; therapeutic drug ; monitoring real-world evidence ; multimorbidity ; medication appropriateness ; model-informed precision dosing; does individualisation; clinical decision support
(This special issue belongs to the Section Pharmacology)
Managing Chronic Kidney Disease: Current Practices and Future Perspectives
edited by Maria L. Gonzalez-Suarez
submission deadline 20 Aug 2026 | Viewed by 290
Keywords: chronic kidney disease; diabetic kidney disease; kidney failure; guideline-directed therapies; SLGT 2 inhibitors; GLP1 receptor agonists
(This special issue belongs to the Section Nephrology & Urology)
From Histology to Clinical Immunology: Integrated Diagnosis in Oral and Maxillofacial Diseases
edited by Fabiana Nicita
submission deadline 20 Aug 2026 | Viewed by 282
Keywords: clinical immunology; histology; immunopathology; immune-mediated oral disease; biomarkers
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Therapeutic Advances and Emerging Treatments in Inflammatory Bowel Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 282
Keywords: inflammatory bowel disease; therapeutic advances emerging treatments; biologics and small molecules; precision medicine in IBD; pharmacokinetic model
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Clinical Perspectives on Chronic Kidney Disease
edited by Luca Visconti
submission deadline 20 Aug 2026 | Viewed by 281
Keywords: chronic kidney disease; nephrology; hemodialysis; renal impairment; renal replacement therapy; new therapeutic approaches in CKD; clinical trials; renal complications
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances in Diagnosis and Treatment of Metastatic Spinal Tumor
edited by
submission deadline 20 Aug 2026 | Viewed by 281
Keywords: metastatic spinal tumors; spine surgery; bone metastasis; imaging diagnosis; minimally invasive surgery; decompression surgery; fixation surgery; emergency surgery; prognosis prediction; elderly patients; nutrition; mental health
(This special issue belongs to the Section Oncology)
Recent Advances in Hypercholesterolemia
edited by Ana Catarina Alves
submission deadline 20 Aug 2026 | Viewed by 277
Keywords: hypercholesterolemia; cardiovascular risk; molecular diagnostics; variants of uncertain significance (VUS); functional characterisation; precision medicine; lipid-lowering therapy
(This special issue belongs to the Section Endocrinology & Metabolism)
Targeting Extravalvular Burden Associated with Valvular Heart Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 269
Keywords: valvular heart disease; systemic disorder; extravalvular burden; valve dysfunction; valve intervention; multimodality imaging
(This special issue belongs to the Section Cardiology)
Pancreatic Cancer: Novel Strategies of Diagnosis and Treatment submission deadline 21 Aug 2026 | 3 articles | Viewed by 6812 | Submission Open
Keywords: pancreatic cancer; chronic pancreatitis; pancreatic intraepithelial neoplasia; gastroenterology; clinical innovative diagnostic; clinical treatment strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life submission deadline 21 Aug 2026 | 5 articles | Viewed by 3556 | Submission Open
Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision
(This special issue belongs to the Section Ophthalmology)
Personalized Modern Oncological Strategies for Breast Cancer Treatment
edited by Vlad Alexandru Gata, Maximilian Muntean and
submission deadline 22 Aug 2026 | 5 articles | Viewed by 4181 | Submission Open
Keywords: breast cancer; targeted and immune therapies; predictive biomarkers; surgical de-escalation; MRI of the breast; breast reconstruction
(This special issue belongs to the Section General Surgery)
Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body
edited by
submission deadline 24 Aug 2026 | 6 articles | Viewed by 20539 | Submission Open
Keywords: reconstructive surgery; academic plastic surgery; research; social media in plastic surgery; breast surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advancements in Cardiomyopathies: Diagnosis, Treatment and Management—2nd Edition submission deadline 24 Aug 2026 | 5 articles | Viewed by 11626 | Submission Open
Keywords: cardiomyopathies; multimodality imaging; cardiac magnetic resonance; genetic testing; cardiogenetics; genetic cardiovascular disease; rare cardiovascular diseases; risk stratification; genotype–phenotype correlations; rare variant interpretation; arrhythmias
(This special issue belongs to the Section Cardiology)
Clinical Advances in Head and Neck Cancer Diagnostics and Treatment
edited by and Alice L. Tang
submission deadline 24 Aug 2026 | 1 articles | Viewed by 1609 | Submission Open
Keywords: head and neck; reconstruction; free flap; surgical margin; biomarker; human papillomavirus (HPV); extranodal extension; immunotherapy; virtual surgical planning
(This special issue belongs to the Section Otolaryngology)
Interventional and Surgical Treatment of Acute and Chronic Pancreatitis
edited by Chirag Desai
submission deadline 25 Aug 2026 | 6 articles | Viewed by 22514 | Submission Open
Keywords: pancreatitis treatment; endoscopic treatment; pancreatic surgery; Whipple; distal pancreatectomy; islet cell auto trans-plant; total pancreatectomy; TPIAT; laparoscopic treatment of pancreatitis; robotic surgery for pancreatitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Alcohol-Related Liver Disease: Diagnosis, Treatment, and Management submission deadline 25 Aug 2026 | 5 articles | Viewed by 16597 | Submission Open
Keywords: alcohol-related liver disease; gut–liver axis; hepatic fibrosis; liver cirrhosis; micro-RNA; inflammatory pathways; liver transplantation; steatohepatitis; fecal microbiota transplantation in liver cirrhosis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Periodontal Diseases and Systemic Health: Pathogenesis, Prevention and Management
edited by
submission deadline 25 Aug 2026 | 8 articles | Viewed by 12885 | Submission Open
Keywords: periodontitis; dental implants; systemic inflammation; diabetes and periodontal disease; cardiovascular implications; pregnancy and oral health; host immune responses; preventive dentistry; implant-prosthetic rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in the Management of Cardiac Amyloidosis and Hypertrophic Cardiomyopathy
edited by Ahmed Abuzaid
submission deadline 25 Aug 2026 | 4 articles | Viewed by 10366 | Submission Open
Keywords: cardiac amyloidosis; hypertrophic cardiomyopathy; left ventricular hypertrophy; non-invasive cardiac imaging; heart failure; clinical manifestations
(This special issue belongs to the Section Cardiology)
New Insights into Cardiorenal Metabolic Syndrome
edited by
submission deadline 25 Aug 2026 | 4 articles | Viewed by 9606 | Submission Open
Keywords: cardiorenal medicine; diabetes; chronic renal failure; heart failure; cardiorenal syndrome; nephrocardiology
(This special issue belongs to the Section Cardiovascular Medicine)
Pain Management: Current Challenges and Future Prospects
edited by Gian Marco Petroni
submission deadline 25 Aug 2026 | 5 articles | Viewed by 8646 | Submission Open
Keywords: chronic joint pain; radio frequency ablation; adipose-derived mesenchimal stem cells (ADMScs); intrarticular injection; facet joint injection with ADMScs
(This special issue belongs to the Section Anesthesiology)
Up-to-Date Research in Liver Transplantation
edited by
submission deadline 25 Aug 2026 | 5 articles | Viewed by 6848 | Submission Open
Keywords: liver transplantation; acute or chronic liver diseases; hepatitis C virus infection; hepatocellular carcinoma (HCC); cirrhosis; intrahepatic (ICCA), perihilar (PCCA) cholangiocarcinoma; unresectable liver metastases; acute or chronic liver failure (ACLF); acute alcoholic hepatitis (AAH)
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Advances and Future Perspectives of Ischemic Stroke
edited by
submission deadline 25 Aug 2026 | 4 articles | Viewed by 6496 | Submission Open
Keywords: acute ischemic stroke care; neuroimaging in ischemic stroke; alteplase and tenecteplase; endovascular treatments; recanalization and reperfusion; prognostication in stroke patients; blood–brain barrier in ischemic stroke; bi-omarkers in ischemic stroke; omics in stroke
(This special issue belongs to the Section Clinical Neurology)
Recent Advances in Prevention, Management, and Rehabilitation of Head and Neck Injuries
edited by , Pier Enrico Gallenga and
submission deadline 25 Aug 2026 | 3 articles | Viewed by 5985 | Submission Open
Keywords: neck injuries; whiplash injuries; head injuries; concussion; neck pain; cervicalgia; post-concussive syndrome; post-concussive symptoms; vision disorders; hearing disorders; emergency care; emergency therapies; physical medicine and rehabilitation; musculoskeletal rehabilitation; sports medicine
(This special issue belongs to the Section Sports Medicine)
Shoulder and Elbow Surgery: Clinical Updates and Perspectives
edited by Taku Hatta, Akihiko Hasegawa and Takuma Yuri
submission deadline 25 Aug 2026 | 5 articles | Viewed by 5545 | Submission Open
Keywords: rotator cuff injuries; shoulder arthroplasty; elbow surgery; shoulder surgery; shoulder and elbow disease; arthroscopic surgery; orthopedic surgery
(This special issue belongs to the Section Orthopedics)
New Insights in Cognitive Aging and Mild Cognitive Impairment submission deadline 25 Aug 2026 | 5 articles | Viewed by 5027 | Submission Open
Keywords: cognitive aging; mild cognitive impairment; normative aging; neuropsychological assessment; diagnosis; gerontology; prevention; intervention; multidisciplinary approach; measurement
(This special issue belongs to the Section Geriatric Medicine)
Clinical Diagnosis and Surgical Strategies Update on Ear Disorders: 2nd Edition submission deadline 25 Aug 2026 | 5 articles | Viewed by 4832 | Submission Open
Keywords: middle ear; inner ear; endoscopic ear surgery; cholesteatoma; Menière’s disease; hearing loss; robotic surgery; oto-sclerosis
(This special issue belongs to the Section Otolaryngology)
Helicobacter pylori-Associated Intestinal Diseases and Beyond submission deadline 25 Aug 2026 | 4 articles | Viewed by 4201 | Submission Open
Keywords: IBD; Hp; stomach; celiac disease; diverticulosis; diverticulitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Etiology, Diagnosis, and Management of Upper Gastrointestinal Disorders: 2nd Edition
edited by
submission deadline 25 Aug 2026 | 2 articles | Viewed by 4044 | Submission Open
Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; helicobacter; eosinophilic esophagitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hospital-Acquired Infections: Evolving Threats and Epidemiological Insights
edited by
submission deadline 25 Aug 2026 | 4 articles | Viewed by 3496 | Submission Open
Keywords: hospital-acquired infections; healthcare-associated infections; antimicrobial resistance; multidrug-resistant organisms (MDRO); infection prevention and control; outbreak investigation; patient safety; healthcare epidemiology
(This special issue belongs to the Section Infectious Diseases)
Current and Emerging Treatment Options in Chronic Liver Diseases
edited by Chandana B. Herath and Michael Praktiknjo
submission deadline 25 Aug 2026 | 2 articles | Viewed by 2861 | Submission Open
Keywords: liver disease; liver fibrosis; liver cirrhosis; portal hypertension; liver cancer; therapies; immunological therapies for liver cancer; diabetic liver; type 2 diabetes and obesity; spontaneous bacterial peritonitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies
edited by
submission deadline 25 Aug 2026 | 3 articles | Viewed by 2818 | Submission Open
Keywords: epithelial barrier dysfunction; intestinal microbiota dysbiosis; minimally invasive surgery in IBDs; disease monitoring; perianal disease treatment; surgical complications in IBD; prehabilitation; stoma formation and management; timing of surgery in IBDs; risk stratification for IBD surgery; patient-reported outcomes post-surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Advances in Clinical Pharmacology Based on Pharmacokinetics
edited by , and
submission deadline 25 Aug 2026 | 1 articles | Viewed by 2499 | Submission Open
Keywords: PK/PD modeling; dose optimization; clinical decision-making tools; therapeutic drug monitoring; personalized medicine
(This special issue belongs to the Section Pharmacology)
Clinical Updates of Diagnosis and Treatment in Chronic Kidney Disease (CKD)
edited by , Carmen Mora-Fernández and
submission deadline 25 Aug 2026 | 1 articles | Viewed by 2378 | Submission Open
Keywords: CKD; CKD progression; biomarkers; disease-modifying treatments; diabetic kidney disease; cardiorenal disease; glomerunephritis; genetic kidney diseases
(This special issue belongs to the Section Nephrology & Urology)
Allergic and Eosinophilic Diseases: Diagnosis, Treatment and Management (Second Edition)
edited by Aikaterini Detoraki
submission deadline 25 Aug 2026 | 1 articles | Viewed by 1931 | Submission Open
Keywords: allergy; eosinophilic diseases; immunology; clinical immunology; asthma; diagnosis; treatment; management
(This special issue belongs to the Section Immunology & Rheumatology)
Current and Emerging Strategies in Ischemic Stroke: Diagnosis, Treatment, and Prevention submission deadline 25 Aug 2026 | 2 articles | Viewed by 1754 | Submission Open
Keywords: diagnosis; digital medicine; epidemiology; ischemic stroke; machine learning; neurorehabilitation; prevention; stroke imaging; treatment
(This special issue belongs to the Section Clinical Neurology)
Clinical Advancements in Orthopedic Trauma Treatments
edited by
submission deadline 25 Aug 2026 | 3 articles | Viewed by 1614 | Submission Open
Keywords: fractures; osteoporosis; fixation; trauma; fracture healing; osteosynthesis; pain
(This special issue belongs to the Section Orthopedics)
Knee Arthroplasty: Recent Advances and Future Challenges
edited by Matteo Marullo
submission deadline 25 Aug 2026 | 2 articles | Viewed by 1477 | Submission Open
Keywords: knee arthroplasty; implant design; robotic surgery; revision surgery; biomechanics; clinical outcomes; perioperative care; fast-track surgery; digital orthopedics; partial knee replacement
(This special issue belongs to the Section Orthopedics)
Gastrointestinal Cancer: Outcomes and Therapeutic Management—2nd Edition
edited by Maximos Frountzas
submission deadline 25 Aug 2026 | 2 articles | Viewed by 1476 | Submission Open
Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm
(This special issue belongs to the Section Oncology)
Complications of Laparoscopic Cholecystectomy: Surgical Outcomes and Clinical Challenges
edited by
submission deadline 25 Aug 2026 | 1 articles | Viewed by 1216 | Submission Open
Keywords: laparoscopic cholecystectomy; bile duct injury; management of intraoperative injuries; surgical outcomes; postoperative infections
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Otologic Disorders and Hearing Impairment: From Diagnosis to Rehabilitation
edited by Andrea Albera and Andrea Canale
submission deadline 25 Aug 2026 | 1 articles | Viewed by 1081 | Submission Open
Keywords: otology; hearing loss; cochlear implants; middle ear surgery; otitis media; otosclerosis; auditory rehabilitation; ves-tibular disorders; hearing aid; bone-conduction implants
(This special issue belongs to the Section Otolaryngology)
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