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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovative Systemic Treatments for Atopic Dermatitis

edited by

Luigi Gargiulo

submission deadline 15 Jul 2026 | 7 articles | Viewed by 30427 | Submission Open

Keywords: atopic dermatitis; atopic eczema; JAK inhibitors; anti-IL-4; anti-IL-13; dupilumab; tralokinumab; lebrikizumab; abrocitinib; upadacitinib; baricitinib

(This special issue belongs to the Section Dermatology)

Advances in Pulmonary Disease Management and Innovation in Treatment

edited by

Monica Steluța Marc

and

Florin Mihaltan

submission deadline 15 Jul 2026 | 12 articles | Viewed by 25726 | Submission Open

Keywords: severe asthma; COPD; sleep-related breathing disorders; respiratory tract infections; innovative respiratory therapies; translational pulmonary research; pulmonary vascular disease; interstitial lung disease; eHealth in respiratory care

(This special issue belongs to the Section Respiratory Medicine)

Current Trends and Prospects of Critical Emergency Medicine

edited by Quincy K. Tran

submission deadline 15 Jul 2026 | 10 articles | Viewed by 17888 | Submission Open

Keywords: critically ill patients; critical care; resuscitation; emergency medicine; trends; prospects; outcomes

(This special issue belongs to the Section Emergency Medicine)

Sarcopenia Across the Lifespan: Risk Factors, Mechanisms, and Management in Aging and Disease

edited by

Juan Mielgo-Ayuso

and

Natalia Busto

submission deadline 15 Jul 2026 | 7 articles | Viewed by 13781 | Submission Open

Keywords: sarcopenia; aging; chronic disease; risk factors; muscle physiology; prevention; nutrition; exercise; treatment strategies

(This special issue belongs to the Section Orthopedics)

Clinical Advances in the Diagnosis and Treatment of Cardiac Arrhythmias

edited by Fabrizio Guarracini and

Marisa Varrenti

submission deadline 15 Jul 2026 | 4 articles | Viewed by 8237 | Submission Open

Keywords: cardiac arrhythmias; antiarrhythmic agents; pacemakers; cardiac resynchronization; catheter ablation; electrophysiology

(This special issue belongs to the Section Cardiology)

Recent Clinical Advances in Percutaneous Coronary Intervention

edited by

Lampson Fan

and Luke Pickup

submission deadline 15 Jul 2026 | 2 articles | Viewed by 6366 | Submission Open

Keywords: complex PCI; calcium modification; left main stem; stent; coronary artery disease; atherectomy; mechanical circula-tory support device; Impella; DCB; intra-coronary imaging; IVUS; OCT

(This special issue belongs to the Section Cardiology)

Total Hip Arthroplasty Today: Trends, Challenges, and Future Directions

edited by

Seung-Jae Lim

submission deadline 15 Jul 2026 | 8 articles | Viewed by 5649 | Submission Open

Keywords: complex hip arthroplasty; surgical technique; innovative implant; new technology; robotic surgery; navigation surgery; artificial intelligence; complications; periprosthetic joint infection; periprosthetic fracture; dislocation

(This special issue belongs to the Section Orthopedics)

Artificial Intelligence in Gastrointestinal Disorders: Current Updates from Theory to Clinical Practice

edited by

Maria Pina Dore

and

Elettra Merola

submission deadline 15 Jul 2026 | 5 articles | Viewed by 4889 | Submission Open

Keywords: artificial intelligence; gastroenterology; medical imaging; endoscopy; prognostic modeling; ethical considerations

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Understanding Dermatitis: Symptoms and Effective Treatment Options

edited by

Emi Sato

and Shinichi Imafuku

submission deadline 15 Jul 2026 | 1 articles | Viewed by 3420 | Submission Open

Keywords: dermatitis; atopic dermatitis; psoriasis; prurigo; JAK inhibitors; real world data

(This special issue belongs to the Section Dermatology)

Neurosurgery Advancements: Techniques and Patient Outcomes

edited by Vianney Gilard

submission deadline 15 Jul 2026 | 3 articles | Viewed by 2961 | Submission Open

Keywords: neurosurgery; minimally invasive surgery; endoscopic spine surgery; intraoperative imaging; neuro-oncology; functional neurosurgery; neurovascular surgery; patient outcomes

(This special issue belongs to the Section Clinical Neurology)

Recent Clinical Advances in Esophageal Surgery

edited by

Guy Pines

, James Tankel and Harbi Khalayleh

submission deadline 15 Jul 2026 | 4 articles | Viewed by 2600 | Submission Open

Keywords: esophageal surgery; minimally invasive surgery; esophageal cancer; robotic surgery; endoscopic resection; benign esophageal disorders; paraesophageal hernia; anti-reflux surgery; motility disorders

(This special issue belongs to the Section General Surgery)

Insights into Acute Pancreatitis: Pathogenesis, Diagnosis, and Management

edited by Gil Nissim Bachar and Ram Dickman

submission deadline 15 Jul 2026 | 1 articles | Viewed by 2533 | Submission Open

Keywords: acute pancreatitis; pancreatic inflammation; necrotizing pancreatitis; clinical outcomes; ultrasound examination

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Fertility Challenges: Modern Management Strategies and Assisted Reproductive Technologies

edited by

Luigi Carbone

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1758 | Submission Open

Keywords: infertility; assisted reproductive technologies (ARTs); ovarian reserve; antral follicle count (AFC); anti-mullerian hormone (AMH); fertility preservation; IVF pregnancy; ovarian stimulation; embryo selection

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options

edited by Przemysław Puz,

Nikolaos Grigoriadis

and

Eduardo Agüera-Morales

submission deadline 15 Jul 2026 | 3 articles | Viewed by 1256 | Submission Open

Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates on Epilepsy Research

edited by

Guillermo Estivill-Torrús

submission deadline 15 Jul 2026 | 2 articles | Viewed by 1124 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Aortic Dissection: Current Trends, Complexities, and Future Directions

edited by Aung Ye Oo

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1088 | Submission Open

Keywords: aortic dissection; aortic surgery; hybrid and endovascular repair; diagnostic delay; systems of care; patient safety; biomarkers and imaging; postoperative outcomes; multidisciplinary collaboration in aortic disease management

(This special issue belongs to the Section Cardiovascular Medicine)

Minimally Invasive Cardiothoracic Surgery: Current Status and Future Perspectives

edited by

Shun-Ichiro Sakamoto

submission deadline 15 Jul 2026 | 1 articles | Viewed by 847 | Submission Open

Keywords: aortic-preserving surgery; hybrid cardiovascular surgery; autologous tissue repair; enhanced recovery after surgery; minimally invasive cardiac surgery (MICS); geriatric surgery

(This special issue belongs to the Section Cardiovascular Medicine)

Glaucoma: Advances in Diagnosis, Management, and Vision Preservation

edited by

Masaki Tanito

and

Takuhei Shoji

submission deadline 15 Jul 2026 | 1 articles | Viewed by 810 | Submission Open

Keywords: glaucoma diagnosis; OCT and OCT angiography; laser therapies (SLT, micropulse, cyclophotocoagulation, etc.); minimally invasive glaucoma surgery (MIGS); long-tube devices; artificial intelligence and imaging; pharmacological therapy; visual field and retinal ganglion cell function

(This special issue belongs to the Section Ophthalmology)

Novel Therapeutic Strategies in Rheumatoid Arthritis

edited by Mislav Radić

submission deadline 15 Jul 2026 | 1 articles | Viewed by 538 | Submission Open

Keywords: rheumatoid arthritis; targeted therapies; biological agents; small molecule inhibitors; biomarkers; personalized medicine; treatment response

(This special issue belongs to the Section Immunology & Rheumatology)

Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment

edited by

Nicholas David Clement

submission deadline 15 Jul 2026 | Viewed by 385 | Submission Open

Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment

(This special issue belongs to the Section Orthopedics)

New Challenges and Perspectives in Polycystic Ovary Syndrome/Polyendocrine Metabolic Ovarian Syndrome: 2nd Edition

edited by

Jim Parker

submission deadline 15 Jul 2026 | Viewed by 245 | Submission Open

Keywords: polycystic ovary syndrome; evolutionary origins; developmental origins; pathogenesis; pathophysiology; microbiome; pregnancy complications; lifestyle

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Challenges and Advancements in Stroke Prevention and Cerebrovascular Disorders

edited by

Ewelina Bak

and Sylwia Krzemińska

submission deadline 15 Jul 2026 | Viewed by 203 | Submission Open

Keywords: risk factors; secondary prevention; health education; health behaviors

(This special issue belongs to the Section Clinical Rehabilitation)

Personalized Medicine for the Management of Non-Communicable Disease (NCDs)

edited by

Alessandro Mattina

, Giulio Geraci and

Vincenzina Lo Re

submission deadline 16 Jul 2026 | 12 articles | Viewed by 26297 | Submission Open

Keywords: personalized medicine; precision medicine; non-communicable disease; cardiovascular disease; cancer; diabetes; chronic obstructive pulmonary disease; cognitive impairment; atherosclerosis; lipids; inflammation; immunity; therapy

(This special issue belongs to the Section Epidemiology & Public Health)

Plastic Surgery: Challenges and Future Directions

edited by Philip Brazio and Edward C. Ray

submission deadline 20 Jul 2026 | 7 articles | Viewed by 21419 | Submission Open

Keywords: plastic surgery; reconstructive surgery; esthetic surgery; innovation; challenges; technology

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Artificial Intelligence (AI) and Deep Learning (DL) in Medical Imaging

edited by

Francesco Pucciarelli

submission deadline 20 Jul 2026 | 6 articles | Viewed by 14665 | Submission Open

Keywords: artificial intelligence; deep learning; imaging; diagnosis; precision medicine; oncologic

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Advances and Perspectives in Cancer Diagnostics and Treatment

edited by Alexandru E. Eniu,

Cristina Marinela Oprean

and

Simona Ruxandra Volovat

submission deadline 20 Jul 2026 | 9 articles | Viewed by 14478 | Submission Open

Keywords: solid tumors; new advances; diagnostics and treatment; clinical–pathological; genetic factors; AI; RWD; radiotherapy; biomarkers; prevention in cancer care; target therapy; immunotherapy

(This special issue belongs to the Section Oncology)

Insights and Innovations in Sports Cardiology

edited by

Garyfallia K. Pepera

submission deadline 20 Jul 2026 | 7 articles | Viewed by 13221 | Submission Open

Keywords: sports cardiology; athlete heart; cardiovascular screening; arrhythmias; sudden cardiac death; cardiac rehabilitation; exercise prescription; mobile health; preventive cardiology; personalized medicine; pediatric fitness

(This special issue belongs to the Section Sports Medicine)

Foot and Ankle Surgery: Current Advances and Prospects

edited by

Jaeho Cho

submission deadline 20 Jul 2026 | 9 articles | Viewed by 12022 | Submission Open

Keywords: foot and ankle surgery; foot pathologies; ankle disease and trauma; diabetic foot; epidemiology; clinical anatomy; foot orthoses; weight-bearing CT

(This special issue belongs to the Section Orthopedics)

Clinical Guidelines in Critical Care Medicine

edited by

Ana Vujaklija Brajković

Andrej Markota

and Daniela Bandic-Pavlovic

submission deadline 20 Jul 2026 | 4 articles | Viewed by 11598 | Submission Open

Keywords: critical illness; immunocompromised host; biomarkers; thrombocytopenia; blood coagulation disorders; multiple trauma; diagnostic imaging

(This special issue belongs to the Section Intensive Care)

Endodontic Disease: Prevalence, Risk Factors, and Treatment Outcome

edited by

Razvan Ionut Ghinea

Ioana-Sofia Pop-Ciutrilă

and

Luminita-Maria Nica

submission deadline 20 Jul 2026 | 4 articles | Viewed by 10760 | Submission Open

Keywords: endodontics; apical periodontitis; pulpitis; root canal treatment; risk factors; treatment outcomes; regenerative endodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiac Arrhythmias: Current Status and Future Directions

edited by

Jackson J. Liang

submission deadline 20 Jul 2026 | 1 articles | Viewed by 10757 | Submission Open

Keywords: ventricular tachycardia; atrial fibrillation; catheter ablation; novel therapies; complex arrhythmias

(This special issue belongs to the Section Cardiology)

Acute Myocardial Infarction: Diagnosis, Treatment, and Rehabilitation

edited by

Francesca Giordana

submission deadline 20 Jul 2026 | 9 articles | Viewed by 10408 | Submission Open

Keywords: acute myocardial infarction; coronary angioplasty; acute heart failure; cardiogenic shock; rehabilitation programs

(This special issue belongs to the Section Cardiovascular Medicine)

Sustaining Success Through Innovation in Kidney Transplantation

edited by Junji Uchida

submission deadline 20 Jul 2026 | 7 articles | Viewed by 9771 | Submission Open

Keywords: kidney transplantation; long-term graft survival; immunosuppression; organ shortage; post-transplant complication

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Autoimmune Disorders

edited by

Chiara Pellicano

and

Edoardo Rosato

submission deadline 20 Jul 2026 | 7 articles | Viewed by 9607 | Submission Open

Keywords: systemic sclerosis; Raynaud’s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis

(This special issue belongs to the Section Immunology & Rheumatology)

State of the Art in Hand Surgery

edited by Leszek Romanowski and

Piotr Czarnecki

submission deadline 20 Jul 2026 | 5 articles | Viewed by 9495 | Submission Open

Keywords: hand surgery; nerve surgery; state-of-the-art; hand therapy; tendons; thumb arthritis; hand fractures

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Management and Treatment of Psoriasis

edited by

Luciano Ibba

submission deadline 20 Jul 2026 | 4 articles | Viewed by 9127 | Submission Open

Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence

(This special issue belongs to the Section Dermatology)

Interventional Cardiology—Challenges and Solutions

edited by

Yonggu Lee

submission deadline 20 Jul 2026 | 5 articles | Viewed by 9111 | Submission Open

Keywords: chronic total occlusion; highly calcified coronary or lower extremity arteries; stentless percutaneous coronary intervention; chronic limb threatening ischemia; instent restenosis in the extremity artery diseases; endovascular therapy for pulmonary thromboembolism; transcatheter aortic valve replacemment for the bicuspid aortic valve; transcatheter aortic valve replacement for the valve-in-valve procedure; endovascular therapy for tricospid valve regurgitation; transcatheter edge-to-edge repair for mitral valve regurgitation

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances in Assessment Measures and Theoretical Models of Caregivers' Sensitivity and Contingency: 2nd Edition

edited by

Silvia Cimino

submission deadline 20 Jul 2026 | 4 articles | Viewed by 9011 | Submission Open

Keywords: clinical caregiving; sensitivity assessment; contingency modeling; caregiver–patient interactions; mental health outcomes; novel assessment measures; therapeutic responsiveness; caregiver interventions; clinical well-being; care recipient support

(This special issue belongs to the Section Intensive Care)

Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies

edited by

Ralph Mösges

submission deadline 20 Jul 2026 | 6 articles | Viewed by 8765 | Submission Open

Keywords: allergy; allergic rhinitis; allergic conjunctivitis; allergic asthma; food allergy; peptide immunotherapy; allergoids; SLIT; SCIT; OIT

(This special issue belongs to the Section Immunology & Rheumatology)

Glaucoma Surgery: Current Challenges and Future Perspectives

edited by

Tina Tzee Ling Wong

and

Esther M. Hoffmann

submission deadline 20 Jul 2026 | 7 articles | Viewed by 7589 | Submission Open

Keywords: glaucoma; filtration surgery; trabeculectomy; MIGS; scarring; anti-metabolites; wound healing; anti-fibrotics

(This special issue belongs to the Section Ophthalmology)

Inflammatory Bowel Diseases: Clinical Advances and Emerging Therapies

edited by

Ewa Malecka-Wojciesko

submission deadline 20 Jul 2026 | 5 articles | Viewed by 7172 | Submission Open

Keywords: inflammatory bowel disease (IBD); ulcerative colitis; Crohn’s disease; gut inflammation; bowel perforation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Artificial Intelligence (AI) in Dental Clinical Practice

edited by

Eiji Tanaka

and Keiichiro Watanabe

submission deadline 20 Jul 2026 | 7 articles | Viewed by 7115 | Submission Open

Keywords: artificial intelligence; dental diagnostics; machine learning; deep learning; digital dentistry; clinical decision support; diagnostic automation; data transparency; evidence-based dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Chronic Kidney Disease: Current Challenges and Adverse Outcomes

edited by

Diana Tania Luminița Moldovan

and Flaviu Bob

submission deadline 20 Jul 2026 | 6 articles | Viewed by 6662 | Submission Open

Keywords: chronic kidney disease; CKD progression; hemodialysis; cardiovascular complications; vascular calcification; lifestyle; nutrition; bone and mineral disorders; CKD-associated osteoporosis; mortality

(This special issue belongs to the Section Nephrology & Urology)

Sarcopenia, Musculoskeletal, and Neuromuscular Disorders: Physical Therapy and Rehabilitation Perspectives

edited by

Do-youn Lee

and

Myoung-Kwon Kim

submission deadline 20 Jul 2026 | 2 articles | Viewed by 6590 | Submission Open

Keywords: sarcopenia; musculoskeletal diseases; neuromuscular disorders; muscle mass; low back pain; neck pain; gait and balance; physical therapy; rehabilitation medicine

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition

edited by Jaime A. Hernández-Montfort

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6552 | Submission Open

Keywords: cardiogenic shock; cardiac arrest; temporary mechanical circulatory support; ECMO; transitions; heart recovery; heart replacement

(This special issue belongs to the Section Cardiology)

New Advances in Hip and Knee Arthroplasty

edited by Jun-Dong Chang

submission deadline 20 Jul 2026 | 7 articles | Viewed by 6293 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; revision surgery; orthopedic implants; robotic surgery; peri-operative care; functional outcomes; complication management; orthopedic innovation

(This special issue belongs to the Section Orthopedics)

Advanced Diagnostic and Therapeutic Strategies for Sarcoidosis

edited by

Małgorzata Sobiecka

and

Monika Szturmowicz

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6216 | Submission Open

Keywords: sarcoidosis; cardiac sarcoidosis; pulmonary fibrosis; magnetic resonance imaging; FDG-PET/CT; echocardiography; neurosarcoidosis; differential diagnosis; hypercalcaemia; IGRA; sarcoidosis-associated pulmonary hypertension; fatigue; corticosteroids; metotrexat; infliximab; antifibrotic treatment; lung transplantation; artificial intelligence; broncho-alveolar lavage; cytokines

(This special issue belongs to the Section Respiratory Medicine)

Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention

edited by Marco Ciardetti and Alessio Mattesini

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6188 | Submission Open

Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification

(This special issue belongs to the Section Cardiology)

From Dual Diagnosis to Dual Disorder(s): Bridging Comorbidity and Integrated Clinical Understanding

edited by

Angelo G. I. Maremmani

submission deadline 20 Jul 2026 | 5 articles | Viewed by 5448 | Submission Open

Keywords: dual diagnosis; dual disorder; psychiatric comorbidity; addiction; integrated care; self-medication; substance use; mental illness; treatment models

(This special issue belongs to the Section Mental Health)

Broadening the Knowledge of Autism Spectrum Disorder in Adulthood: Advances in Diagnosis, Assessment and Treatment

edited by

Camilla Gesi

submission deadline 20 Jul 2026 | 1 articles | Viewed by 4788 | Submission Open

Keywords: autism spectrum disorder; adulthood; autism; comorbidity; gender; age-adjusted

(This special issue belongs to the Section Mental Health)

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