Fertility Challenges: Modern Management Strategies and Assisted Reproductive Technologies
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Reproductive Medicine & Andrology".
Deadline for manuscript submissions: 15 July 2026 | Viewed by 16
Special Issue Editor
Interests: ovarian reserve; antral follicle count; 3D-AFC; fertility preservation; fertility in multiple sclerosis; assisted repro-ductive technology; ovarian stimulation; IVF pregnancy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue, titled "Fertility Challenges: Modern Management Strategies and Assisted Reproductive Technologies," addresses the growing global concern of infertility by exploring the latest clinical advancements, delving into modern diagnostic approaches for both male- and female-factor infertility.
The aim of this Special Issue is to provide a comprehensive overview of recent advances in assisted reproduction and to explore the challenges encountered at various stages of treatment. Topics include criteria for couples undergoing ART treatments or fertility preservation, assessment of ovarian reserve with new methods such as 3D antral follicle count, ovarian stimulation protocols (including dual trigger, dual stimulation, PPOS protocols, type and dose of gonadotropin, and pharmacogenomics), embryo transfer, and endometrial preparation—focusing on the window of implantation and endometrial receptivity (considering endometrial metabolism, immunology, and the microbiome)—culminating in pregnancy outcomes after IVF. Focus is placed on managing complex cases, including recurrent implantation failure and diminished ovarian reserve.
This Issue also examines time-lapse imaging for embryo selection, preimplantation genetic testing (PGT), and optimized cryopreservation techniques, such as vitrification.
By synthesizing evidence-based management strategies with technological innovations, this collection aims to provide clinicians and researchers with a comprehensive resource to improve patient counseling, treatment personalization, and, ultimately, clinical outcomes in reproductive medicine.
Dr. Luigi Carbone
Guest Editor
Manuscript Submission Information
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Keywords
- infertility
- assisted reproductive technologies (ARTs)
- ovarian reserve
- antral follicle count (AFC)
- anti-mullerian hormone (AMH)
- fertility preservation
- IVF pregnancy
- ovarian stimulation
- embryo selection
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