Inflammatory Bowel Diseases: Clinical Advances and Emerging Therapies

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 25 July 2025 | Viewed by 698

Special Issue Editor


E-Mail Website
Guest Editor
Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland
Interests: pancreatic diseases; inflammatory bowel diseases; esophageal; stomach; intestinal dysfunctions
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Inflammatory bowel disease (IBD) includes mainly ulcerative colitis and Crohn’s disease, which are chronic, progressive diseases.

IBD management is complicated and includes mesalasine, steroids, immunosuppressants, and many new biologic drugs, such as anti-tumor necrosis factor-alpha (TNF-α) agents, anti-integrin agents, anti-interleukin (IL) 12-23 agents, and non-biologic small molecules. The number of available biologics is rapidly growing in recent years and their choice depends on IBD clinical course, previous treatments, including biologics, potential adverse effects, accompanying diseases, and patient’s preferences. Optimal treatment should aim, on the one hand, at clinical remission, endoscopic and histopathologic healing, and prolonged response and, on the other hand, at side effects and complication avoidance.

This Special Issue is dedicated to showcasing the latest clinical advancements in inflammatory bowel disease (IBD). We invite researchers and clinicians to submit their original research articles and reviews that contribute to the understanding, diagnosis, treatment, and management of IBD.

Prof. Dr. Ewa Malecka-Wojciesko
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammatory bowel disease (IBD)
  • ulcerative colitis
  • Crohn’s disease
  • gut inflammation
  • bowel perforation

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

12 pages, 235 KiB  
Article
Quality of Life in Patients with Inflammatory Bowel Diseases Is Associated with Affective Temperament Traits: A Cross-Sectional Survey of a Polish Clinical Sample
by Anna Mokrowiecka, Magdalena Kopczynska, Alina Borkowska and Ewa Malecka-Wojciesko
J. Clin. Med. 2025, 14(3), 1018; https://doi.org/10.3390/jcm14031018 - 5 Feb 2025
Viewed by 504
Abstract
Background: Affective temperaments can be considered the subclinical manifestations of affective and stress-related disorders, which could have a relationship with many chronic diseases. The purpose of this study was to explore the influence of affective temperament traits on disease-specific quality of life in [...] Read more.
Background: Affective temperaments can be considered the subclinical manifestations of affective and stress-related disorders, which could have a relationship with many chronic diseases. The purpose of this study was to explore the influence of affective temperament traits on disease-specific quality of life in patients with ulcerative colitis (UC) and Crohn’s disease (CD), two types of inflammatory bowel disease (IBD). Methods: The patients completed the Temperament Evaluation of the Memphis, Pisa, Paris, San Diego-Auto-questionnaire (TEMPS-A), which is the 110-item self-reported assessment for five dimensions of temperament: depressive, cyclothymic, hyperthymic, irritable, and anxious, already validated in Poland. For comprehensive assessment of the health-related quality of life (HRQoL), the Inflammatory Bowel Disease Questionnaire (IBDQ) was applied. Results: The study included 116 patients with IBD-61 with UC and 55 with CD, with mean age 43 years, in remission, without serious mental or medical co-morbidities. Mean HRQoL in patients with IBD was poor and mean IBDQ scores were 145, despite clinical remission. A significant negative correlation was found between HRQoL in all the IBDQ domains and TEMPS-A traits: D (p < 0.001), C (p < 0.01), I (p < 0.05), and A (p < 0.001). No significant correlation between hyperthymic temperament and IBDQ scores was found. Conclusions: Poor quality of life in IBD could be associated with affective temperament. Affective temperament traits should be taken into account when identifying patients at risk of worse IBD course and further introducing personalized therapy. Full article
(This article belongs to the Special Issue Inflammatory Bowel Diseases: Clinical Advances and Emerging Therapies)
Back to TopTop