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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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PET/CT Imaging in Oncology: Clinical Updates and Prospects
edited by Ahmad Shariftabrizi
submission deadline 28 Oct 2025 | Viewed by 59 | Submission Open
Keywords: new radiotracers; PET radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy outcome prediction; PET physics; normal tissue PET/CT; synchronous malignancies
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Diagnosis, Treatment, and Management of Gastrointestinal Oncology
edited by Toufic A. Kachaamy and Madappa N. Kundranda
submission deadline 30 Oct 2025 | 1 articles | Viewed by 7262 | Submission Open
Keywords: gastrointestinal oncology; endoscopic oncology; biliary tract cancer; colorectal cancer; esophageal cancer; stomach cancer
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Biomarkers and Lung Cancer: Clinical Application
edited by
submission deadline 30 Oct 2025 | 5 articles | Viewed by 4559 | Submission Open
Keywords: lung cancer; early diagnosis; prognosis; biomarkers; body fluids; liquid biopsy
(This special issue belongs to the Section Respiratory Medicine)
New Update on Personalized Treatment of Autism Spectrum Disorder and Related Disorders
edited by , Rosamaria Siracusano and Erica Pironti
submission deadline 30 Oct 2025 | 1 articles | Viewed by 3567 | Submission Open
Keywords: autism spectrum disorder; autism related disorders; children and adolescents; intervention strategies; therapeutic advance; new technologies; evidence-based practices
(This special issue belongs to the Section Mental Health)
Advances in Anesthesia for Cardiac Surgery
edited by Christopher M. Munch and
submission deadline 30 Oct 2025 | 3 articles | Viewed by 3402 | Submission Open
Keywords: enhanced recovery after cardiac surgery (ERACS); minimally invasive cardiac surgery (MICS); ultra-fast-track an-esthesia; chest wall blocks in cardiac anesthesia; opioid-free anesthesia in cardiac surgery; neurologic dysfunction and cardiac surgery; pre- and posthabilitation in cardiac surgery
(This special issue belongs to the Section Anesthesiology)
Clinical Highlights in Chronic Obstructive Pulmonary Disease (COPD)
edited by and Dimosthenis Lykouras
submission deadline 30 Oct 2025 | 3 articles | Viewed by 2428 | Submission Open
Keywords: COPD treatment; inhalers; patient-reported outcomes; COPD rehabilitation; cardiovascular risk
(This special issue belongs to the Section Respiratory Medicine)
New Advances in Minimally Invasive Surgery for Gynecologic Cancer submission deadline 30 Oct 2025 | 1 articles | Viewed by 2119 | Submission Open
Keywords: minimally invasive surgery; gynecologic surgery; gynecologic oncology; surgical techniques; patient safety; personalized medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Facial Plastic and Cosmetic Medicine
edited by
submission deadline 30 Oct 2025 | 1 articles | Viewed by 1486 | Submission Open
Keywords: cosmetics; aesthetics; plastic surgery; skin rejuvenation; beauty; procedures
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Clinical Challenges in High-Risk Pregnancy and Delivery submission deadline 30 Oct 2025 | 1 articles | Viewed by 882 | Submission Open
Keywords: high-risk pregnancy; preeclampsia; cesarean section; maternal– fetal medicine; ultrasound; fetal monitoring; complications; delivery; placental abruption; great obstetrical syndromes
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Ocular Surface Research: Exploring Antimicrobial Resistance and Emerging Therapeutics
edited by , Giovanni Alessio and Maria Gabriella la Tegola
submission deadline 30 Oct 2025 | 1 articles | Viewed by 450 | Submission Open
Keywords: ocular surface microbiome; antimicrobial resistance; ocular infections and therapeutics; novel diagnostics in ophthalmology; biofilms and pathogen evolution; infection control and public health
(This special issue belongs to the Section Ophthalmology)
Advances in Anesthesia and Intensive Care During Perioperative Period
edited by
submission deadline 30 Oct 2025 | 1 articles | Viewed by 448 | Submission Open
Keywords: general anesthesia; intensive care medicine; post intensive care syndrome; perioperative management; fast track; pain management; complications; postoperative outcome; digitalization; big data; AI; closed-loop systems; machine learning; clinical decision support; telemedicine
(This special issue belongs to the Section Intensive Care)
Advancements in Venous Thrombosis Management: From Prevention to Long-Term Care
edited by
submission deadline 30 Oct 2025 | Viewed by 344 | Submission Open
Keywords: venous thromboembolism; post-thrombotic syndrome; direct oral anticoagulant; pulmonary embolism; thrombosis; factor xia inhibitors; thrombolysis; cancer; antiphospholipid syndrome; catheter-directed thrombolysis; inferior vena cava filters
(This special issue belongs to the Section Vascular Medicine)
Advancements and Challenges in Reconstructive Urology and Urethral Surgery
edited by
submission deadline 30 Oct 2025 | 1 articles | Viewed by 333 | Submission Open
Keywords: reconstructive urology; urethral surgery; urethroplasty; minimally invasive surgery; robotic-assisted surgery; urinary tract reconstruction; surgical innovation; patient-reported outcomes
(This special issue belongs to the Section Nephrology & Urology)
Innovations in Perioperative Anesthesia and Intensive Care
edited by and Ileana Lulic
submission deadline 30 Oct 2025 | 1 articles | Viewed by 314 | Submission Open
Keywords: perioperative anesthesia; intensive care; artificial intelligence in anesthesia; precision medicine in perioperative care; hemodynamic monitoring; multimodal analgesia; opioid-free anesthesia; ventilation strategies in ICU and surgery; neuromonitoring and sedation; perioperative resuscitation and ECMO
(This special issue belongs to the Section Intensive Care)
Advances in Gastroenterological Surgery
edited by Alan Biloslavo and Antonio La Greca
submission deadline 30 Oct 2025 | Viewed by 252 | Submission Open
Keywords: mini-invasive surgery; technology; artificial intelligence; negative pressure; indocyanine green; ultrasound; GE surgery; emergency surgery; precision surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Artificial Intelligence and Deep Learning in Medical Imaging
edited by Eros Montin and Giuseppe Carluccio
submission deadline 30 Oct 2025 | Viewed by 135 | Submission Open
Keywords: magnetic resonance imaging; radiomics; artificial intelligence (AI); deep learning; clinical and translational medicine; MRI safety; radiogenomics; multiomics
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Spine Surgery: Current Practice and Future Directions
edited by Claudio Bernucci and Francesco Costa
submission deadline 30 Oct 2025 | Viewed by 132 | Submission Open
Keywords: degenerative; spinal trauma; spine tumors; neurosurgery; spine surgery; spinal deformity; scoliosis; robotics surgery; spinal cord injury; clinical practices; regenerative therapies
(This special issue belongs to the Section Clinical Neurology)
Drug Therapy and Prognosis in Patients with Heart Failure submission deadline 30 Oct 2025 | Viewed by 131 | Submission Open
Keywords: heart failure; drug therapy; prognosis; pharmacological innovations; cardiovascular outcomes; personalized medicine; heart failure management
(This special issue belongs to the Section Cardiology)
Clinical Update on Thoracic Trauma
edited by
submission deadline 30 Oct 2025 | Viewed by 119 | Submission Open
Keywords: flail chest; isolated sternal fractures; manubrio-sternal dislocation; pneumothorax; hemothorax; thoracic aortic injury; heart and pulmonary vessels lesion; intercostal artery injury; diaphragm rupture; thoracoabdominal hernia; chylothorax; esophageal perforation
(This special issue belongs to the Section Respiratory Medicine)
Prosthetic Joint Infections: Contemporary Insights into Their Management and Prevention
edited by and Uwe Maus
submission deadline 30 Oct 2025 | Viewed by 115 | Submission Open
Keywords: arthroplasty; infection; replacement; antibiotics; management; hip; knee; shoulder; periprosthetic; prevention; implant retention; procedure; implant retention; debridement; cellular infection; infection markers
(This special issue belongs to the Section Orthopedics)
Catheter Ablation of Atrial Fibrillation: Current Progress and New Challenges
edited by Sorin Stefan Popescu, Roland Richard Tilz and Karl-Heinz Kuck
submission deadline 30 Oct 2025 | Viewed by 105 | Submission Open
Keywords: atrial fibrillation; novel technologies; pulmonary vein isolation; same-day discharge; pulsed field ablation; cryo-ablation; radiofrequency; safety; efficacy; sustainability
(This special issue belongs to the Section Cardiology)
Prostatectomy: Clinical Updates and Perspectives
edited by Antonio Nacchia
submission deadline 30 Oct 2025 | 1 articles | Viewed by 98 | Submission Open
Keywords: single port; prostatectomy; robotics; RARP; prostate cancer
(This special issue belongs to the Section Nephrology & Urology)
Advances in Atrial Fibrillation Treatment
edited by Iwona Woźniak-Skowerska
submission deadline 30 Oct 2025 | Viewed by 94 | Submission Open
Keywords: pulmonary vein ablation; atrial fibrillation; heart failure; arrhythmia; personalized medicine
(This special issue belongs to the Section Cardiovascular Medicine)
Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy
edited by , Francesco Costa and Filippo Maria Polli
submission deadline 30 Oct 2025 | Viewed by 88 | Submission Open
Keywords: degenerative cervical myelopathy (DCM); cervical spondylotic myelopathy (CSM); cervical spinal stenosis; cervical cord compression; MRI of the cervical spine; cervical spine surgery; physical therapy; rehabilitation; ossification of the posterior longitudinal ligament (OPLL); cervical deformity (e.g.; kyphosis and lordosis); patient-reported out-comes; surgical outcome prediction
(This special issue belongs to the Section Clinical Neurology)
Myeloproliferative Neoplasms (MPN): Recent Advances, Current Practices and Future Perspectives
edited by Arumugam Manoharan
submission deadline 31 Oct 2025 | 7 articles | Viewed by 11403 | Submission Open
Keywords: diagnosis; pathogenesis; prognosis; thromboprophylaxis; treatment
(This special issue belongs to the Section Hematology)
Progress in Patient Safety and Quality in Maternal–Fetal Medicine
edited by Samuel T. Bauer
submission deadline 31 Oct 2025 | 7 articles | Viewed by 8386 | Submission Open
Keywords: maternal– fetal medicine; pregnancy; postpartum; medical error; maternity; fetus
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Advances in Endodontics and Dental Traumatology
edited by Karin Christine Huth
submission deadline 31 Oct 2025 | 6 articles | Viewed by 3658 | Submission Open
Keywords: endodontology; traumatology; regeneration; biocompatibility; dental materials; antimicrobial; dynamic and static navigation in endodontics; under- and postgraduate education in endodontology and traumatology; artificial intelligence; autotransplantation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovations and Challenges in Clinical Toxicology and Therapeutic Drug Monitoring
edited by Zhicheng Jin
submission deadline 31 Oct 2025 | 1 articles | Viewed by 3162 | Submission Open
Keywords: toxicology screen; therapeutic drug monitoring; mass spectrometry; immunoassays; pain management; opioids
(This special issue belongs to the Section Pharmacology)
Chronic Renal Disease: Diagnosis, Treatment, and Management
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 1437 | Submission Open
Keywords: acute kidney injury; chronic kidney disease; cardio– renal syndromes; clinical nephrology; diagnosis and management
(This special issue belongs to the Section Nephrology & Urology)
Youth Sports Injuries: From Prevalence to Prevention
edited by Swarup Mukherjee and
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1307 | Submission Open
Keywords: youth sports injuries; musculoskeletal injuries; injury prevention; sport safety; youth athletes
(This special issue belongs to the Section Sports Medicine)
Clinical Management of Oral Healthcare in Diverse Patient Populations: Second Edition submission deadline 31 Oct 2025 | 1 articles | Viewed by 1245 | Submission Open
Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Advances in Procedures for the Diagnosis and Treatment of Cardiovascular Disease submission deadline 31 Oct 2025 | Viewed by 1160 | Submission Open
Keywords: cardiovascular disease; diagnostic procedures; therapeutic advancements; minimally invasive interventions; precision medicine; imaging technologies; catheter-based treatments; translational research; interventional cardiology; clinical innovations
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Care and Rehabilitation for Neuromuscular Diseases submission deadline 31 Oct 2025 | Viewed by 718 | Submission Open
Keywords: neuromuscular diseases; myopathy; neuropathy; motor neuron disease; amyotrophic lateral sclerosis; diseases of neuromuscular junction; neurorehabilitation; rehabilitation; clinical care; neuroscience
(This special issue belongs to the Section Clinical Rehabilitation)
Cardiogenic Shock and Cardiac Arrest: Updates, Challenges and Opportunities
edited by Torben K. Becker
submission deadline 31 Oct 2025 | 2 articles | Viewed by 684 | Submission Open
Keywords: cardiac arrest; extracorporeal membrane oxygenation; extracorporeal CPR; cardiopulmonary resuscitation; cardiogenic shock; resuscitation; prognostication
(This special issue belongs to the Section Cardiology)
New Perspective of Oral and Maxillo-Facial Surgery
edited by , and Alessandra Lucchese
submission deadline 31 Oct 2025 | 1 articles | Viewed by 511 | Submission Open
Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Novel Technologies to Assist Emergency Medical Care
edited by and Young Soon Cho
submission deadline 31 Oct 2025 | 1 articles | Viewed by 331 | Submission Open
Keywords: emergency medical services; artificial intelligence in emergency medicine; telemedicine and remote patient monitoring; wearable health technologies; point-of-care diagnostics; automated decision support systems; robotics in emergency medicine; pre-hospital care innovations
(This special issue belongs to the Section Emergency Medicine)
Diabetic Retinopathy Screening: Current Advances and Future Options submission deadline 31 Oct 2025 | 1 articles | Viewed by 263 | Submission Open
Keywords: diabetic retinopathy; diabetic retinopathy screening; retinal imaging; age-related macular degeneration; artificial intelli-gence; image analysis; color fundus photography; optical coherence tomography imaging; telemedicine
(This special issue belongs to the Section Ophthalmology)
Complex Spine Surgery: The Road from Childhood to Adults and Future Directions
edited by Jacob M. Buchowski, and Michael A. Galgano
submission deadline 31 Oct 2025 | Viewed by 260 | Submission Open
Keywords: complex spine; scoliosis; kyphosis; spinal deformities; spinal tumor; spinal reconstruction; sagittal balance; coronal imbalance
(This special issue belongs to the Section Clinical Neurology)
Interstitial Lung Diseases: New Treatments and Future Directions
edited by Justyna Fijołek
submission deadline 31 Oct 2025 | Viewed by 185 | Submission Open
Keywords: Interstitial Lung Disease (ILD); pulmonary fibrosis; orphan lung disease; AAV-ILD; occupational ILD; rheumatic lung disease; treatment strategies; emerging therapies; precision medicine; future directions
(This special issue belongs to the Section Respiratory Medicine)
Advancing Minimally Invasive Spine Surgery: A Special Edition on Endoscopic Spine Surgery
edited by and Gregory W. Basil
submission deadline 31 Oct 2025 | Viewed by 168 | Submission Open
Keywords: minimally invasive spine surgery (MIS); endoscopic spine surgery (ESS); spine surgery; percutaneous spine surgery; full-endoscopic spine surgery; biportal endoscopic spine surgery (BESS); unilateral biportal endoscopy (UBE); percutaneous endoscopic lumbar discectomy (PELD); endoscopic decompression; transforaminal endoscopic lumbar discectomy (TELD); interlaminar endoscopic lumbar discectomy (IELD); endoscopic lumbar fusion; endoscopic transforaminal lumbar interbody fusion (Endo-TLIF)
(This special issue belongs to the Section Clinical Neurology)
Current Trends in Hand Surgery
edited by and Florian Frueh
submission deadline 31 Oct 2025 | Viewed by 161 | Submission Open
Keywords: microsurgery; minimally invasive; arthroscopy; sonography; nerve surgery; joint replacement
(This special issue belongs to the Section Orthopedics)
Current Trends and Future Prospects in Autoantibodies in Liver Diseases
edited by Takashi Himoto
submission deadline 31 Oct 2025 | Viewed by 142 | Submission Open
Keywords: liver-specific autoantibodies; non-organ-specific autoantibodies; autoimmune liver disease; diagnosis; disease activity; treatment outcome; prognosis; virus-induced autoimmunity; drug-induced autoimmunity
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Novel Insights into Neonatal Intensive Care
edited by and Maria Baltogianni
submission deadline 31 Oct 2025 | Viewed by 137 | Submission Open
Keywords: neonatology; neonatal intensive care; neonate; sepsis; nutrition; ventilation; hemodynamic; neurodevelopment
(This special issue belongs to the Section Clinical Pediatrics)
Current Updates and Advances in Hemodialysis
edited by Edita Žiginskienė
submission deadline 31 Oct 2025 | Viewed by 134 | Submission Open
Keywords: kidney replacement therapy; hemodialysis; hemodiafiltration; vascular access; dialysis membranes; dialysis complications; dialysis adequacy; outcomes
(This special issue belongs to the Section Nephrology & Urology)
Recent Advances in the Epidemiology of Infectious Diseases: A Clinical Perspective submission deadline 31 Oct 2025 | Viewed by 129 | Submission Open
Keywords: epidemiology of infectious diseases; global health and infectious diseases; hospital-acquired infections (HAIs); infection control; novel treatments; vaccine effectiveness
(This special issue belongs to the Section Epidemiology & Public Health)
Advances in the Diagnosis and Treatment of Skin Cancer submission deadline 31 Oct 2025 | Viewed by 126 | Submission Open
Keywords: skin cancer; melanoma; keratinocyte carcinoma; basal cell carcinoma; squamous cell carcinoma; biomarkers; immuno-therapy; prognosis
(This special issue belongs to the Section Oncology)
Imaging in Diagnosis and Treatment of Musculoskeletal Disorders
edited by Francesco Porta and
submission deadline 31 Oct 2025 | Viewed by 125 | Submission Open
Keywords: ultrasound; ultrasound-guided injections; imaging-guided procedures
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Immunotherapy of Hematological Malignancies: The State of the Art submission deadline 31 Oct 2025 | Viewed by 115 | Submission Open
Keywords: antibody-drug conjugates; bispecific antibodies; chimeric antigen receptor-engineered natural killer cell; chimeric antigen receptor T-cells; cytokine release syndrome; immune checkpoint in-hibitors; immunosuppression; immunotherapy; monoclonal antibodies; neurotoxicities
(This special issue belongs to the Section Hematology)
Current Challenges and Innovations in Spine Deformity: Biomechanics, Imaging and AI-Driven Analysis
edited by Dong-Ho Kang
submission deadline 31 Oct 2025 | Viewed by 112 | Submission Open
Keywords: spinal deformity; cervical deformity; biomechanics; postural alignment; sagittal imbalance; medical imaging; radiographic analysis; artificial intelligence; machine learning; deep learning; phenotyping; computer-assisted diagnosis; predictive modeling; surgical planning
(This special issue belongs to the Section Orthopedics)
Clinical Updates in Pediatric Radiology submission deadline 31 Oct 2025 | Viewed by 104 | Submission Open
Keywords: pediatric radiology; advances in pediatric imaging; pediatric neuroimaging; artificial in-telligence in pediatric imaging; radiomics and machine learning; low-field MRI techniques; magnetic resonance imaging in pediatrics; computed tomography in pediatrics; radiation dose optimization; patient-centred imaging protocols
(This special issue belongs to the Section Clinical Pediatrics)
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