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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current and Emerging Treatment Options in Intestinal and Stomach Neoplasms submission deadline 20 Dec 2025 | Viewed by 83 | Submission Open
Keywords: colorectal cancer; colon cancer; gastric carcinoma; malignancy; gastroenterology; endoscopic techniques; therapeutic advancements; intestinal neoplasms
(This special issue belongs to the Section Oncology)
New Perspectives in Maternal–Fetal Medicine
edited by Catalina de Paco-Matallana
submission deadline 20 Dec 2025 | Viewed by 81 | Submission Open
Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health
(This special issue belongs to the Section Obstetrics & Gynecology)
Neurological Rehabilitation: Repair Mechanisms, Plasticity, and Connectomes
edited by Thomas Mokrusch and Frank Kirchhoff
submission deadline 20 Dec 2025 | Viewed by 80 | Submission Open
Keywords: neurorehabilitation; therapeutic approaches; repair mechanism; plasticity; neurology
(This special issue belongs to the Section Clinical Neurology)
Recent Developments in Urinary Incontinence
edited by
submission deadline 20 Dec 2025 | Viewed by 75 | Submission Open
Keywords: urinary incontinence; overactive bladder; stress urinary incontinence; pelvic floor dysfunction; urodynamics; minimally invasive treatment; neuromodulation; regenerative medicine; conservative management; digital health in urology
(This special issue belongs to the Section Nephrology & Urology)
Surgical Oncology: Clinical Application of Translational Medicine
edited by Domenico Parmeggiani
submission deadline 20 Dec 2025 | Viewed by 73 | Submission Open
Keywords: surgical oncology; drug safety; adverse events; nanovesicles; targeted drug delivery; cancer biomarkers; precision oncology; tumor microenvironment; nanomedicine; personalized medicine; diagnostics; prognosis; innovative therapies; translational research
(This special issue belongs to the Section Oncology)
Clinical Research and Insights in Endometriosis
edited by
submission deadline 20 Dec 2025 | Viewed by 73 | Submission Open
Keywords: endometriosis; pelvic pain; infertility; inflammation; minimal access surgery; laparoscopy; hysteroscopy; robotics
(This special issue belongs to the Section Obstetrics & Gynecology)
Elevating Standards in Anesthesia Monitoring
edited by
submission deadline 20 Dec 2025 | Viewed by 72 | Submission Open
Keywords: monitoring; analgesia; pain; nociception; awareness anesthesia; postoperative delirium; closed-loop anes-thesia; artificial intelligence
(This special issue belongs to the Section Anesthesiology)
Status, Application and Future Directions of Artificial Urinary Sphincters
edited by JiSung Shim
submission deadline 20 Dec 2025 | Viewed by 68 | Submission Open
Keywords: ISD; robot surgery; neurogenic SUI; female AUS; complication; erosion; urethroplasty; malfunction; PPI; BOO
(This special issue belongs to the Section Nephrology & Urology)
The Treatment of BPO with Minimal Invasive Approach
edited by
submission deadline 20 Dec 2025 | Viewed by 66 | Submission Open
Keywords: benign prostatic obstruction (BPO); prostatectomy; non-muscle invasive bladder cancer; muscle invasive bladder cancer; robotic surgery
(This special issue belongs to the Section Nephrology & Urology)
Clinical Perspectives of Vascular and Endovascular Surgeries submission deadline 20 Dec 2025 | Viewed by 64 | Submission Open
Keywords: vascular surgery; varicose veins; abdominal aortic aneurysms; carotid disease; peripheral arterial disease
(This special issue belongs to the Section Vascular Medicine)
Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice
edited by
submission deadline 20 Dec 2025 | Viewed by 64 | Submission Open
Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse
(This special issue belongs to the Section Cardiology)
Parkinson's Disease: Recent Advances in Diagnosis and Treatment submission deadline 20 Dec 2025 | Viewed by 61 | Submission Open
Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging
(This special issue belongs to the Section Clinical Neurology)
Advances in Lung Transplantation and Interventional Pulmonology
edited by Anupam Kumar and Frye Laura
submission deadline 20 Dec 2025 | Viewed by 60 | Submission Open
Keywords: lung transplantation; interventional pulmonology; immunosuppressive therapies; organ rejection; pulmonary rehabilitation; surgical innovations; post-transplant complications; diagnostic advancements; donor lung shortage; thoracic surgery
(This special issue belongs to the Section Respiratory Medicine)
Advanced Technologies, Concepts, and Topics in Modern Neurosurgery
edited by and Ralf Stroop
submission deadline 20 Dec 2025 | Viewed by 57 | Submission Open
Keywords: modern neurosurgery; virtual reality; augmented reality; intraoperative imaging; neuronavigation; artificial intelligence; machine learning; robotic surgery; 3D printing; neurovascular interventions; neuro-oncology; skull base surgery; functional neurosurgery; spinal neurosurgery; surgical innovation; image-guided surgery; personalized neurosurgical planning
(This special issue belongs to the Section General Surgery)
Laparoscopy and Surgery in Gynecologic Oncology: 2nd Edition
edited by Zoltan Novak
submission deadline 20 Dec 2025 | Viewed by 55 | Submission Open
Keywords: gynecologic cancers; ovarian; uterine; cervical; laparoscopy; diagnosis; staging; treatment; palliative care; fertility preservation
(This special issue belongs to the Section Obstetrics & Gynecology)
Applications of Artificial Intelligence in Cardiology: New Tools to Transform Care submission deadline 20 Dec 2025 | Viewed by 55 | Submission Open
Keywords: artificial intelligence in cardiology; machine learning; deep learning; AI-driven ECG analysis; cardiovas-cular imaging and AI; predictive analytics in cardiology; mHealth and wearables; clinical decision support systems; ethics and AI in healthcare; digital health and remote monitoring
(This special issue belongs to the Section Cardiology)
Hospital-Acquired Infections: Insights, Prevention, and Control Strategies
edited by
submission deadline 20 Dec 2025 | Viewed by 45 | Submission Open
Keywords: healthcare-acquired infections; bloodstream infections; hospital‐acquired pneumonia; intestinal infections; clostridium difficile; surgical site infections; urinary tract infections; emergency department
(This special issue belongs to the Section Epidemiology & Public Health)
Current Perspectives and Innovations in Urogynecology
edited by Stavros Athanasiou
submission deadline 20 Dec 2025 | Viewed by 45 | Submission Open
Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Clinical Management of Temporomandibular Joint Diseases submission deadline 20 Dec 2025 | Viewed by 43 | Submission Open
Keywords: minimally invasive surgical procedure; artificial intelligence; temporomandibular joint disorders; temporomandibular disorders; temporomandibular joint
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Gastric Cancer: Epidemiology, Clinical Management and Emerging Biomarkers submission deadline 20 Dec 2025 | Viewed by 37 | Submission Open
Keywords: gastric cancer; metabolism; biomarkers; surgical stress; adjuvant therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advanced Image-Enhanced Endoscopy and Colonoscopy
edited by , and Simona Di Caro
submission deadline 20 Dec 2025 | Viewed by 34 | Submission Open
Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Innovations in Preeclampsia
edited by Jeffrey M. Denney and
submission deadline 22 Dec 2025 | 3 articles | Viewed by 5285 | Submission Open
Keywords: preeclampsia; pathophysiology; renin; SFlt-1; PlGF; hypertensive disorders of pregnancy; imitators of preeclampsia; vascular reactivity
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances of Adolescent Idiopathic Scoliosis: Current Status and Prospects
edited by Maria Chiara Maccarone and
submission deadline 22 Dec 2025 | 2 articles | Viewed by 1646 | Submission Open
Keywords: adolescent idiopathic scoliosis; treatment; non-invasive therapies; surgery; neurophisiology; imaging; motion analysis; personalized medicine
(This special issue belongs to the Section Orthopedics)
Scoliosis: Advances in Diagnosis and Management
edited by Michal Latalski
submission deadline 22 Dec 2025 | Viewed by 165 | Submission Open
Keywords: scoliosis; adolescent idiopathic scoliosis; adult scoliosis; congenital scoliosis; neuromuscular scoliosis; diagnosis; imaging; treatment; surgery; bracing; rehabilitation; patient-reported outcomes; quality of life
(This special issue belongs to the Section Orthopedics)
Oral Surgery: Recent Advances and Future Perspectives submission deadline 22 Dec 2025 | Viewed by 106 | Submission Open
Keywords: oral surgery; implant dentistry; atrophic jaws; bone regeneration; digital dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovative Aspects in Dental Implantology and Related Clinical Research (Second Edition) submission deadline 22 Dec 2025 | Viewed by 82 | Submission Open
Keywords: dental implants; implantology; bone regeneration; implant-supported prosthesis; zygomatic implants; reconstructive surgery; pre-implant surgery; short implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Ablation, Embolization, and Stenting: Current Trends in Interventional Radiology
edited by Praveen Peddu
submission deadline 22 Dec 2025 | Viewed by 47 | Submission Open
Keywords: interventional radiology; ablation; embolization; stenting; minimally invasive therapy
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Advances in Stereotactic Radiosurgery
edited by Shafak S. Aluwini
submission deadline 24 Dec 2025 | Viewed by 71 | Submission Open
Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery
(This special issue belongs to the Section Oncology)
Sports Injury: Clinical Prevention and Treatment
edited by , Susana Pulgar and
submission deadline 25 Dec 2025 | 3 articles | Viewed by 7593 | Submission Open
Keywords: injury prevention; team sports; talent identification; biobanding; injury burden; muscle injury; PHV
(This special issue belongs to the Section Sports Medicine)
Skin Diseases: From Diagnosis to Treatment
edited by
submission deadline 25 Dec 2025 | 4 articles | Viewed by 7399 | Submission Open
Keywords: skin; melanoma; NMSC; CTCL; mesenchymal
(This special issue belongs to the Section Dermatology)
Technological Advances, Innovative Applications, and New Clinical Benefits of Computed Tomography submission deadline 25 Dec 2025 | 3 articles | Viewed by 6701 | Submission Open
Keywords: computed tomography (CT); spectral CT; dual-energy CT; dual-source spectral CT; dual-layer spectral CT; pho-ton-counting CT; photon-counting detector CT; spectral photon-counting CT; artificial intelligence; radiomics
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Pathogenesis, Diagnosis, and Management of Upper Gastrointestinal Disease
edited by
submission deadline 25 Dec 2025 | 3 articles | Viewed by 6439 | Submission Open
Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; Helicobacter; eosinophilic esophagitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Epidemiology in Chronic Kidney Disease
edited by and Claudia Torino
submission deadline 25 Dec 2025 | 6 articles | Viewed by 6079 | Submission Open
Keywords: chronic kidney disease; end-stage kidney disease; dialysis; hypertension; renal disease; clinical nephrology; chronic renal failure
(This special issue belongs to the Section Nephrology & Urology)
New Clinical Advances in Sudden Cardiac Arrest and Ventricular Arrhythmias
edited by
submission deadline 25 Dec 2025 | 4 articles | Viewed by 6042 | Submission Open
Keywords: cardiac arrest; defibrillation; ventricular tachycardia; ventricular fibrillation; catheter ablation; non-invasive ablation; neuromodulation; stellate ganglion block
(This special issue belongs to the Section Cardiology)
Anterior Cruciate Ligament (ACL): Innovations in Clinical Management
edited by Xaver Feichtinger, and Georg Brandl
submission deadline 25 Dec 2025 | 4 articles | Viewed by 4505 | Submission Open
Keywords: ACL; graft choice; ACL repair; ALL; tibial slope
(This special issue belongs to the Section Orthopedics)
Innovations in Maxillofacial Surgery
edited by , and Ignacio Navarro Cuéllar
submission deadline 25 Dec 2025 | 4 articles | Viewed by 2816 | Submission Open
Keywords: orthognathic surgery; sleep apnea; 3D technologies; regenerative medicine; reconstructive surgery; facial trauma; minimally invasive surgery; oncology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Advances in Inflammatory and Infectious Skin Diseases (Second Edition)
edited by , Astrid Herzum and Paolo Romita
submission deadline 25 Dec 2025 | 3 articles | Viewed by 2741 | Submission Open
Keywords: atopic dermatitis; eczematous diseases; inflammatory skin diseases; chronic skin diseases; human herpesvirus; roseola syphilitica; psoriasis
(This special issue belongs to the Section Dermatology)
Clinical Advances in Radiation Therapy for Cancers submission deadline 25 Dec 2025 | 2 articles | Viewed by 1286 | Submission Open
Keywords: radiation oncology; radiotherapy; cancer radiotherapy; cancer radiation therapy; radiobiology; predictive and prognostic biomarkers; cancer treatment; heavy ions radiation oncology; protontherapy; cancer biolology
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Exploring Artificial Intelligence in Precision Medicine for Gastrointestinal Diseases
edited by Vincenzo Davide Palumbo
submission deadline 25 Dec 2025 | 2 articles | Viewed by 1168 | Submission Open
Keywords: cholangiocarcinoma; biliary tree stenoses; colorectal cancer; endoscopic image analysis; IBD; gastrointestinal disorders
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Headache: Updates on the Assessment, Diagnosis and Treatment submission deadline 25 Dec 2025 | 2 articles | Viewed by 1038 | Submission Open
Keywords: headache; migraine; tension-type headache; cervicogenic headache; therapeutic exercise
(This special issue belongs to the Section Clinical Neurology)
Recent Research Progress in Pediatric Orthopedic Surgery
edited by and Madeleine Willegger
submission deadline 25 Dec 2025 | 1 articles | Viewed by 471 | Submission Open
Keywords: pediatric orthopedics; deformity correction; pediatric hip; pediatric trauma; basic research in pediatric orthopedics; clubfoot; pediatric foot and ankle deformities; pediatric hand
(This special issue belongs to the Section Clinical Pediatrics)
State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities
edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan
submission deadline 25 Dec 2025 | 1 articles | Viewed by 416 | Submission Open
Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts
(This special issue belongs to the Section Cardiology)
Pulmonary Embolism: Clinical Advances and Future Opportunities
edited by James Horowitz
submission deadline 25 Dec 2025 | Viewed by 399 | Submission Open
Keywords: pulmonary embolism; risk stratification; pulmonary embolism response teams; high risk PE; massive PE; intermediate risk PE; sub massive PE; catheter directed thrombolysis; catheter thrombectomy; catheter directed embolectomy; extra corporeal membrane oxygenation
(This special issue belongs to the Section Respiratory Medicine)
Advances in Anterior Segment Surgery: Second Edition
edited by
submission deadline 25 Dec 2025 | 1 articles | Viewed by 256 | Submission Open
Keywords: lenticule-based surgery; surface ablations; blended vision treatments with laser refractive surgery; corneal inlay procedures; presbyopia management with monovision laser vision correction; refractive lens exchange; premium presbyopia-correcting intraocular lens; refractive solutions for keratoconics; cataract surgery; corneal transplant; biometry
(This special issue belongs to the Section Ophthalmology)
New Insights in Skin Tumors: From Pathogenesis to Therapy
edited by Loredana Ungureanu and Simona C. Şenilǎ
submission deadline 25 Dec 2025 | 1 articles | Viewed by 233 | Submission Open
Keywords: skin tumors; pathogenesis; diagnosis; personalized medicine; therapeutic strategies; dermato-oncology
(This special issue belongs to the Section Dermatology)
Kidney Health Under Microscope
edited by
submission deadline 25 Dec 2025 | Viewed by 219 | Submission Open
Keywords: complications; IgA nephropathy; glomerulonephritis; atypical haemolytic uraemic syndrome; systemic vasculitis; lupus nephritis; mineral bone disease; anaemia; xenotransplantation; nephrolithiasis
(This special issue belongs to the Section Nephrology & Urology)
Cardiac Imaging Techniques in Heart Failure Care
edited by David Snipelisky
submission deadline 25 Dec 2025 | Viewed by 182 | Submission Open
Keywords: heart failure; advanced imaging; cardiac imaging; echocardiography; cardiomyopathies
(This special issue belongs to the Section Cardiology)
Psychological Pain and Suicidal Behavior: Clinical Implications
edited by Adrián Alacreu-Crespo
submission deadline 25 Dec 2025 | Viewed by 104 | Submission Open
Keywords: suicidal behavior; psychological pain; pain tolerance; therapeutic interventions; clinical outcomes
(This special issue belongs to the Section Mental Health)
Advances and Innovations in Hand Surgery
edited by , Jason Wink and Anthony Archual
submission deadline 25 Dec 2025 | Viewed by 102 | Submission Open
Keywords: hand surgery; peripheral nerve surgery; shared decision making; microsurgery; arthritis; compression neuropathy; carpal tunnel; cubital tunnel
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Myocardial Infarction: Clinical Management and Future Options
edited by
submission deadline 25 Dec 2025 | Viewed by 74 | Submission Open
Keywords: myocardial infarction; percutaneous coronary intervention; optimal medical therapy; clinical outcomes; cardiogenic shock; mechanical cardiac support device
(This special issue belongs to the Section Cardiology)
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