Mitral Valve Stenosis or Aortic Valve Stenosis: Progress from Diagnosis to Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: 28 March 2026 | Viewed by 7
Special Issue Editor
Special Issue Information
Dear Colleagues,
Degenerative valve disease with fibrocalcific aortic and mitral valve stenosis represents an increasing issue in the context of an aging population and evolving treatment options. While surgery remains the standard treatment for mitral valve stenosis—especially in degenerative forms—transcatheter aortic valve implantation (TAVI) has become an established therapy for aortic stenosis. However, percutaneous options for degenerative mitral valve stenosis are not yet standardized and remain under-investigated. The long-standing debate between surgical and transcatheter approaches in aortic stenosis continues, and the optimal timing of intervention remains controversial, particularly in asymptomatic severe disease and symptomatic moderate disease. Moreover, the presence of concomitant valvular disease presents a particularly challenging clinical scenario. Finally, some diagnostic issues are still open, especially in estimating mitral valve area in degenerative mitral disease compared to rheumatic disease or in the context of aortic stenosis, given the recent identification of the fibrotic phenotype.
In this Special Issue, we invite the submission of original research articles and reviews focused on diagnostic strategies, timing of intervention, long-term outcomes, and novel techniques for addressing mitral and/or aortic stenosis. Contributions exploring the management of concomitant valvular disease are especially encouraged.
We look forward to receiving your work.
Dr. Francesco Melillo
Guest Editor
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Keywords
- aortic stenosis
- mitral stenosis
- TAVI
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