Myeloid-Derived Suppressor and Innate Immune Cells in Hematologic, Malignant and Chronic Diseases
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Hematology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 64
Special Issue Editor
2. Department of Hematology, University Hospital of Heraklion, 71500 Heraklion, Greece
Interests: neutropenia; bone marrow failure; clonal hematopoiesis; myeloid derived suppressor cells; umbilical cord blood
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is my honor to serve as the Guest Editor of the Special Issue “Myeloid-Derived Suppressor and Innate Immune Cells in Hematologic, Malignant and Chronic Diseases” of Journal of Clinical Medicine, and I would like to invite you to submit a relevant review and/or original paper with new data from your clinical and/or translational research in the field.
The innate immune system functions in a more complicated way than traditionally thought, through humoral and cellular components. Innate immune cells, including macrophages, monocytes, neutrophils and innate lymphoid cells, mediate complex interactions and immune responses in chronic, inflammatory and malignant diseases. A special type of innate immune cells are Myeloid-Derived Suppressor Cells (MDSCs), an immature myeloid cell population with immunosuppressive properties. A better understanding of MDSCs’ and innate cells’ involvement in health and disease states could lead to the development of new biomarkers for diagnostic and personalized treatment approaches.
This Issue, which has the aim of discussing matters associated with research on MDSCs and other immune cells in a variety of disease conditions, will give an opportunity to researchers in the field, particularly young ones, to promote their work and advance current knowledge of these interesting cell populations. The content of this Issue is broad and we encourage the submission of papers on a wide range of topics and perspectives including, but not restricted to, biological mechanisms, new diagnostic techniques, new biomarkers of disease severity and treatment responses, novel and established therapeutic agents and strategies, as well as related reviews.
I look forward to receiving your submissions.
Prof. Dr. Helen A. Papadaki
Guest Editor
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Keywords
- myeloid-derived suppressor cells (MDSCs)
- macrophages
- monocytes
- eosinophils
- neutrophils
- malignancy
- cancer
- autoimmunity
- infection
- chronic inflammation
- therapeutic target
- biomarker
- precision medicine
- molecular pathways
- bone marrow microenvironment
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