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Recent Clinical Perspective in Kidney Transplantation

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 255

Special Issue Editor


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Guest Editor
Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, Clinical Hospital Centre Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia
Interests: chronic kidney disease; dialysis; apheresis; kidney transplantation; renal nutrition

Special Issue Information

Dear Colleagues,

Kidney transplantation remains the gold standard for treating end-stage renal disease, offering superior survival and quality of life compared to dialysis. Despite significant progress in surgical techniques and immunosuppressive therapies, challenges such as chronic graft dysfunction, limited donor availability, immunological barriers, and long-term complications continue to impact outcomes.

This Special Issue invites original research articles and comprehensive reviews that address these challenges and explore innovative solutions. We encourage submissions on topics including donor organ quality and preservation, immunological risk and desensitization strategies, rejection monitoring, personalized immunosuppression, novel biomarkers, infection and malignancy management, surgical advances, and donor pool expansion through ABO-incompatible transplants and paired exchange programs. By promoting interdisciplinary collaboration, this Special Issue aims to enhance understanding and drive advancements in kidney transplantation to improve patient care and long-term graft survival.

Dr. Nikolina Bašić-Jukić
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • kidney transplantation
  • outcomes
  • desensitization
  • xenotransplantation
  • transplant nephropathology
  • multiorgan transplantations
  • post-transplant complications
  • inequities in transplantation

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Published Papers (1 paper)

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Research

20 pages, 1677 KB  
Article
Changes in Body Composition Compartments After Kidney Transplantation: A One-Year Prospective Study
by Emilia Ferrer-López, Raúl López-Blasco, Francisco Javier Rubio-Castañeda, Víctor Cantín-Lahoz, Juan José Aguilón-Leiva, María García-Magán, Carlos Navas-Ferrer, Isabel Blázquez-Ornat, María Teresa Fernández-Rodrigo, Isabel Antón-Solanas and Fernando Urcola-Pardo
J. Clin. Med. 2025, 14(20), 7131; https://doi.org/10.3390/jcm14207131 - 10 Oct 2025
Viewed by 177
Abstract
Background/Objectives: Weight gain after kidney transplantation is frequent but heterogeneous, often accompanied by changes in body composition that influence long-term outcomes. This study analysed one-year changes in body compartments and their demographic and clinical determinants. Methods: A prospective cohort of 112 [...] Read more.
Background/Objectives: Weight gain after kidney transplantation is frequent but heterogeneous, often accompanied by changes in body composition that influence long-term outcomes. This study analysed one-year changes in body compartments and their demographic and clinical determinants. Methods: A prospective cohort of 112 adult kidney recipients transplanted between September 2020 and June 2022 at a Spanish tertiary hospital was followed. Body weight, muscle mass, fat mass, visceral fat and total body water were assessed by multi-frequency bioelectrical impedance at discharge, and at 3, 6 and 12 months. Associations with sociodemographic, clinical and comorbidity variables were examined using repeated-measures ANOVA and comparative tests. Results: At 12 months, mean weight gain was 3.6 ± 6.5 kg (5.1%). Increases were greater in men, younger patients, non-dialysis candidates, those with previous transplantation and living donor grafts. Muscle mass rose during the first three months and then stabilised, with greater gains in men and haemodialysis patients. Fat mass decreased initially and then increased, particularly in women, younger recipients and living donor transplants. Visceral fat progressively increased after three months, with higher levels in men and older patients. Total body water declined in women, younger recipients and first transplant patients. Patients with new-onset diabetes gained less weight, while smokers gained more. Conclusions: Post-transplant body composition is shaped by sex, age, BMI, comorbidities and donor type. Monitoring compartments beyond body weight may allow early detection of adverse metabolic trajectories. Tailored nutritional and lifestyle interventions are needed to optimise long-term outcomes. Full article
(This article belongs to the Special Issue Recent Clinical Perspective in Kidney Transplantation)
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