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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Vascular and Endovascular Surgery: Second Edition

edited by

Fadi Taher

and Afshin Assadian

submission deadline 11 Jan 2026 | 4 articles | Viewed by 3255 | Submission Open

Keywords: vascular surgery; endovascular surgery; aortic surgery; peripheral arterial disease; vascular imaging; EVAR; FEVAR; vascular access; vascular education; aneurysms

(This special issue belongs to the Section Vascular Medicine)

Clinical Updates in Physiotherapy for Musculoskeletal Disorders

edited by

Santiago Navarro Ledesma

submission deadline 15 Jan 2026 | 10 articles | Viewed by 26757 | Submission Open

Keywords: musculoskeletal disorders; physiotherapy interventions; lifestyle; psychoneuroimmunology; chronic pain; inflammation; physical therapy

(This special issue belongs to the Section Clinical Rehabilitation)

Physical Therapy in Neurorehabilitation

edited by

Marianna Papadopoulou

and

George K. Papadimas

submission deadline 15 Jan 2026 | 8 articles | Viewed by 20747 | Submission Open

Keywords: physical therapy; transcutaneous electrical nerve stimulation (TENS); muscle strengthening; balance exercising; pain; quality of life; neurodegenerative disorders; neuromuscular disorders; stroke; demyelinating disorders

(This special issue belongs to the Section Clinical Neurology)

Innovative Systemic Treatments for Atopic Dermatitis

edited by

Luigi Gargiulo

submission deadline 15 Jan 2026 | 5 articles | Viewed by 15787 | Submission Open

Keywords: atopic dermatitis; atopic eczema; JAK inhibitors; anti-IL-4; anti-IL-13; dupilumab; tralokinumab; lebrikizumab; abrocitinib; upadacitinib; baricitinib

(This special issue belongs to the Section Dermatology)

Clinical Application of Biomarkers in Cancers

edited by

Monica Florescu

submission deadline 15 Jan 2026 | 3 articles | Viewed by 13774 | Submission Open

Keywords: cancer biomarkers; early detection; personalized therapy; biomarker validation; advanced technologies; clinical implementation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Current Trends and Prospects of Critical Emergency Medicine

edited by Quincy K. Tran

submission deadline 15 Jan 2026 | 8 articles | Viewed by 8106 | Submission Open

Keywords: critically ill patients; critical care; resuscitation; emergency medicine; trends; prospects; outcomes

(This special issue belongs to the Section Emergency Medicine)

Advances in Pulmonary Disease Management and Innovation in Treatment

edited by

Monica Steluța Marc

and

Florin Mihaltan

submission deadline 15 Jan 2026 | 4 articles | Viewed by 6588 | Submission Open

Keywords: severe asthma; COPD; sleep-related breathing disorders; respiratory tract infections; innovative respiratory therapies; translational pulmonary research; pulmonary vascular disease; interstitial lung disease; eHealth in respiratory care

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Assessment Measures and Theoretical Models of Caregivers' Sensitivity and Contingency: 2nd Edition

edited by

Silvia Cimino

submission deadline 15 Jan 2026 | 3 articles | Viewed by 4710 | Submission Open

Keywords: clinical caregiving; sensitivity assessment; contingency modeling; caregiver– patient interactions; mental health outcomes; novel assessment measures; therapeutic responsiveness; caregiver interventions; clinical well-being; care recipient support

(This special issue belongs to the Section Intensive Care)

Pulmonary Embolism—Current and Novel Approaches

edited by Roy Beigel and Shlomi Matetzky

submission deadline 15 Jan 2026 | 3 articles | Viewed by 4499 | Submission Open

Keywords: pulmonary embolism; treatment; coagulation; venous thrombosis; thrombolysis; anticoagulation; risk stratification

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Minimally Invasive Urologic Surgery

edited by

Umberto Carbonara

, Fabio Crocerossa and

Savio Domenico Pandolfo

submission deadline 15 Jan 2026 | 3 articles | Viewed by 3880 | Submission Open

Keywords: urology; uro-oncology; uro-gynecology; robotic surgery; laparoscopy; robot-assisted; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Safety in Spinal Surgery

edited by Simon B. Roberts and

Thanos Tsirikos

submission deadline 15 Jan 2026 | 1 articles | Viewed by 3845 | Submission Open

Keywords: spinal surgery; patients with spinal deformity; inherent risks; risk management; surgery safety

(This special issue belongs to the Section General Surgery)

Clinical Management and Treatment of Psoriasis

edited by

Luciano Ibba

submission deadline 15 Jan 2026 | 2 articles | Viewed by 3414 | Submission Open

Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence

(This special issue belongs to the Section Dermatology)

Clinical Advances in the Diagnosis and Treatment of Cardiac Arrhythmias

edited by Fabrizio Guarracini and

Marisa Varrenti

submission deadline 15 Jan 2026 | 3 articles | Viewed by 2949 | Submission Open

Keywords: cardiac arrhythmias; antiarrhythmic agents; pacemakers; cardiac resynchronization; catheter ablation; electrophysiology

(This special issue belongs to the Section Cardiology)

Up-to-Date Research in Liver Transplantation

edited by

Pierluigi Toniutto

submission deadline 15 Jan 2026 | 1 articles | Viewed by 2375 | Submission Open

Keywords: liver transplantation; acute or chronic liver diseases; hepatitis C virus infection; hepatocellular carcinoma (HCC); cirrhosis; intrahepatic (ICCA); perihilar (PCCA) cholangiocarcinoma; unresectable liver metastases; acute or chronic liver failure (ACLF); acute alcoholic hepatitis (AAH)

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis and Management of Aortic Diseases: Drafting from Theoretical Aspects to Clinical Practice—2nd Edition

edited by

Mario D’Oria

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1853 | Submission Open

Keywords: aortic disease; aortic aneurysm; aortic dissection; aortic surgery; diagnosis and management

(This special issue belongs to the Section Cardiovascular Medicine)

Pediatric Nephrology: Advances in the Diagnosis and Management of Pediatric Kidney Disorders

edited by

Agnieszka Rybi-Szumińska

and

Anna Maria Wasilewska

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1718 | Submission Open

Keywords: diagnosis; management; treatment; kidney disorders; chronic kidney disease; biomarkers; genetic testing; kidney; children; newborn

(This special issue belongs to the Section Nephrology & Urology)

Recent Clinical Advances in Percutaneous Coronary Intervention

edited by

Lampson Fan

and Luke Pickup

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1571 | Submission Open

Keywords: complex PCI; calcium modification; left main stem; stent; coronary artery disease; atherectomy; mechanical circula-tory support device; Impella; DCB; intra-coronary imaging; IVUS; OCT

(This special issue belongs to the Section Cardiology)

Intracranial Hemorrhage: Advances in Diagnosis, Management and Treatment

edited by Hitoshi Fukuda

submission deadline 15 Jan 2026 | 1 articles | Viewed by 944 | Submission Open

Keywords: intracerebral hemorrhage; subarachnoid hemorrhage; traumatic hemorrhage; prehospital care; less invasive surgery; vascular malformation; antihypertensive drug; intracranial pressure elevation; decompressive craniectomy; neurocritical care; nursing care; rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Pediatric Urology: How to Adapt Current Knowledge to the New Era

edited by Simona Gerocarni Nappo and

Elisa Cerchia

submission deadline 15 Jan 2026 | 1 articles | Viewed by 435 | Submission Open

Keywords: pediatric urology; telemedicine; telesurgery; artificial intelligence; 3D-models; congenital urinary diseases; pediatric oncology

(This special issue belongs to the Section Clinical Pediatrics)

Advances in Oculoplastic Surgery and Ocular Surface Diseases

edited by Michael T. Yen, Francesco Quaranta Leoni and

Balestrazzi Alessandra

submission deadline 15 Jan 2026 | Viewed by 210 | Submission Open

Keywords: ocular surface disease; corneal neurotization; neurotrophic keratopathy; eyelid malposition; facial nerve palsy; thyroid eye disease; oculoplastic surgery; hemocomponents; dry anophthalmic socket; corneal pathology; ocular surface reconstruction; exposure keratopathy

(This special issue belongs to the Section Ophthalmology)

Chronic Kidney Disease: Current Challenges and Adverse Outcomes

edited by

Diana Tania Luminița Moldovan

and Flaviu Bob

submission deadline 15 Jan 2026 | Viewed by 159 | Submission Open

Keywords: chronic kidney disease; CKD progression; hemodialysis; cardiovascular complications; vascular calcification; lifestyle; nutrition; bone and mineral disorders; CKD-associated osteoporosis; mortality

(This special issue belongs to the Section Nephrology & Urology)

Advances in Minimally Invasive Cardiothoracic Surgery: Current Techniques and Future Innovations

edited by

Akshay Kumar

and

Mohamed Rahouma

submission deadline 15 Jan 2026 | Viewed by 150 | Submission Open

Keywords: cardiothoracic surgery; lung cancer; cardiac imaging; minimally invasive surgery; thoracic oncology

(This special issue belongs to the Section Cardiovascular Medicine)

Pulmonary Critical Care: Diagnosis and Treatment of Respiratory System Diseases

edited by Yaron Bar-Lavie

submission deadline 15 Jan 2026 | Viewed by 143 | Submission Open

Keywords: acute respiratory distress syndrome (ARDS); mechanical ventilation; chronic obstructive pulmonary disease (COPD); sepsis-induced lung injury; pulmonary fibrosis; bronchoscopy in critical care

(This special issue belongs to the Section Intensive Care)

Insights into Acute Pancreatitis: Pathogenesis, Diagnosis, and Management

edited by Gil Nissim Bachar and Ram Dickman

submission deadline 15 Jan 2026 | Viewed by 136 | Submission Open

Keywords: acute pancreatitis; pancreatic inflammation; necrotizing pancreatitis; clinical outcomes; ultrasound examination

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Artificial Intelligence in Gastrointestinal Disorders: Current Updates from Theory to Clinical Practice

edited by

Maria Pina Dore

and

Elettra Merola

submission deadline 15 Jan 2026 | Viewed by 134 | Submission Open

Keywords: artificial intelligence; gastroenterology; medical imaging; endoscopy; prognostic modeling; ethical considerations

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Epilepsy Researches

edited by

Guillermo Estivill-Torrús

submission deadline 15 Jan 2026 | Viewed by 133 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Clinical Diagnosis and Management of Chronic Venous Diseases

edited by

Sigitas Urbonavičius

submission deadline 15 Jan 2026 | Viewed by 96 | Submission Open

Keywords: varicose veins; chronic venous insufficiency; pathogenesis; operative treatment; conservative treatment; profilaxis

(This special issue belongs to the Section Vascular Medicine)

Novel Sepsis and Post-Sepsis Care: The Heart and Beyond

edited by Alexander Liu and

Barbara J. Philips

submission deadline 16 Jan 2026 | Viewed by 246 | Submission Open

Keywords: sepsis; post sepsis; inflammation; cardiomyopathy; heart failure; cardiac imaging; biomarkers; novel therapies; prognosis; clinical outcomes

Innovations in Plastic and Reconstructive Research

edited by Damiano Tambasco and Roberta Albanese

submission deadline 18 Jan 2026 | 4 articles | Viewed by 6113 | Submission Open

Keywords: microvascular surgery; 3D printing; regenerative medicine; aesthetic surgery; minimally invasive techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

New Advances in Hip and Knee Arthroplasty

edited by Jun-Dong Chang

submission deadline 18 Jan 2026 | 1 articles | Viewed by 962 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; revision surgery; orthopedic implants; robotic surgery; peri-operative care; functional outcomes; complication management; orthopedic innovation

(This special issue belongs to the Section Orthopedics)

New Technologies in Neurosurgery: An Insight into the Future

edited by Ismail Zaed

submission deadline 19 Jan 2026 | 1 articles | Viewed by 1636 | Submission Open

Keywords: neurosurgery; training; technology; augmented reality; virtual reality; robot

(This special issue belongs to the Section Clinical Neurology)

Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment

edited by

Shunsuke Mori

submission deadline 20 Jan 2026 | 12 articles | Viewed by 38312 | Submission Open

Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety

(This special issue belongs to the Section Immunology & Rheumatology)

Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Recent Advances and Perspectives

edited by Ehud I. Assia

submission deadline 20 Jan 2026 | 14 articles | Viewed by 19305 | Submission Open

Keywords: premium IOLs (multifocal and toric); IOL power calculation; biometry and imaging; complications and management; laser vision correction; phakic IOLs; femtosecond-laser-assisted cataract surgery; AI (artificial intelligence) and cataract/refractive surgery; accommodative lenses

(This special issue belongs to the Section Ophthalmology)

Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management

edited by

Ilias Migdalis

submission deadline 20 Jan 2026 | 9 articles | Viewed by 18570 | Submission Open

Keywords: pathogenesis of diabetic complications; epidemiology of diabetic complications; diabetic retinopathy; diabetic chronic kidney disease; diabetes neuropathies; coronary heart disease; peripheral vascular disease; hypertension and dyslipidemia in diabetes

(This special issue belongs to the Section Endocrinology & Metabolism)

Hernia Surgery and Postoperative Management

edited by Jacob Rosenberg

submission deadline 20 Jan 2026 | 5 articles | Viewed by 15589 | Submission Open

Keywords: hernia surgery; hernia repair; abdominal hernia; preoperative; intraoperative; postoperative; management; complications

(This special issue belongs to the Section General Surgery)

New Insights into Infectious Skin and Mucosal Diseases

edited by

Giulia Ciccarese

Sebastiano Recalcati

and Astrid Herzum

submission deadline 20 Jan 2026 | 6 articles | Viewed by 15453 | Submission Open

Keywords: exanthem; latent viruses; infectious diseases; skin eruptions; sexually transmitted infections

(This special issue belongs to the Section Dermatology)

Advanced Strategies and Innovations to Enhance Outcomes in Cardiac Ablation

edited by

Nikolaos K. Fragakis

and

Paschalis Karakasis

submission deadline 20 Jan 2026 | 4 articles | Viewed by 12165 | Submission Open

Keywords: arrhythmias; cardiac ablation; catheter technology; imaging; anticoagulation optimization; post-procedure care

(This special issue belongs to the Section Cardiology)

POTS, ME/CFS and Long COVID: Recent Advances and Future Direction

edited by Svetlana Blitshteyn

submission deadline 20 Jan 2026 | 2 articles | Viewed by 12085 | Submission Open

Keywords: POTS; ME/CFS; long COVID; dysautonomia; orthostatic intolerance; autoimmunity

(This special issue belongs to the Section Immunology & Rheumatology)

Multidisciplinarity in Thoraco-Pulmonary Diseases: Every Generation Needs a New Revolution. Insights from the XXII SIET National Meeting

edited by Federico Raveglia,

Carmelina C. Zirafa

and

Mohsen Ibrahim

submission deadline 20 Jan 2026 | 7 articles | Viewed by 11805 | Submission Open

Keywords: lung cancer; interventional endoscopy; upper airway reconstruction; robotic diagnosis; robotic surgery

(This special issue belongs to the Section Respiratory Medicine)

Oral Health in Children: Clinical Management

edited by

Yolanda Martinez Beneyto

submission deadline 20 Jan 2026 | 7 articles | Viewed by 9778 | Submission Open

Keywords: pediatric oral health; early childhood caries; preventive strategies; comprehensive clinical approach; early detection; oral care; minimal intervention dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Traumatic Brain Injury: Current Treatment and Future Options

edited by

Ismail Zaed

submission deadline 20 Jan 2026 | 5 articles | Viewed by 8999 | Submission Open

Keywords: traumatic brain injury; trauma; biomarkers; post-traumatic outcome; epidemiology

(This special issue belongs to the Section Clinical Neurology)

Foot and Ankle Surgery: State of the Art and Future Perspectives

edited by Sung Jae Kim and Jaehwang Song

submission deadline 20 Jan 2026 | 5 articles | Viewed by 8969 | Submission Open

Keywords: foot and ankle surgery; hallux disorders; lesser toe problem; diabetic foot salvage; calcaneal fracture; pilon fracture; ligament disorder

(This special issue belongs to the Section Orthopedics)

Attention-Deficit/Hyperactivity Disorder (ADHD): Advances in Diagnosis and Treatment

edited by Yanli Zhang-James

submission deadline 20 Jan 2026 | 3 articles | Viewed by 8825 | Submission Open

Keywords: attention-deficit/hyperactivity disorder; neurodevelopmental disorder; hyperactivity; children; adolescents; adult

(This special issue belongs to the Section Clinical Neurology)

Plastic Surgery: Challenges and Future Directions

edited by Philip Brazio and Edward C. Ray

submission deadline 20 Jan 2026 | 4 articles | Viewed by 7566 | Submission Open

Keywords: plastic surgery; reconstructive surgery; esthetic surgery; innovation; challenges; technology

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Innovative Clinical Approaches in Oral Health Prevention and Management

edited by

Giulia Orilisi

Rossana Izzetti

and Flavia Vitiello

submission deadline 20 Jan 2026 | 6 articles | Viewed by 7452 | Submission Open

Keywords: oral health; oral prevention; teeth remineralization; oral pathology; oral health management; preventive dentistry; translational dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiovascular Imaging: Opportunities and Challenges in Clinical Application: 3rd Edition

edited by

Kana Fujikura

and Panagiota Christia

submission deadline 20 Jan 2026 | 4 articles | Viewed by 6846 | Submission Open

Keywords: echocardiography; cardiovascular magnetic resonance imaging; cardiovascular computed tomography imaging; nuclear cardiology imaging; stress test with imaging; multimodality cardiovascular imaging; cardiomyopathy; coronary artery disease; microvascular disease; valvular heart disease

(This special issue belongs to the Section Cardiology)

Peripheral Nerves: Imaging, Electrophysiology and Surgical Techniques

edited by

Raffaele Natella

, Aniello Iovino and Vito Stifano

submission deadline 20 Jan 2026 | 4 articles | Viewed by 6172 | Submission Open

Keywords: MRI; MSK imaging; soft-tissue tumors; DTI; neuropathies; inflammatory neuropathies; nerve entrapment; motor neuron disease; neurophysiology; MSK ultrasound; peripheral nerve tumor; nerve entrapment; nerve reconstruction

(This special issue belongs to the Section Clinical Neurology)

Hip Fracture and Surgery: Clinical Updates and Challenges

edited by

Norio Imai

submission deadline 20 Jan 2026 | 4 articles | Viewed by 6135 | Submission Open

Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty

(This special issue belongs to the Section Orthopedics)

Advancing Psycho-Oncology: Multidimensional Approaches and Challenges to Cancer Care

edited by

Benedetta Muzii

Nelson Mauro Maldonato

and

Andrea Bovero

submission deadline 20 Jan 2026 | 3 articles | Viewed by 5894 | Submission Open

Keywords: psycho-oncology; cancer care; adaptation process; illness experience; risk and protective factors; mental health care; oncofertility; palliative care; critical experience; prevention; qualitative and quantitative methods; quality of life; health behaviors

(This special issue belongs to the Section Mental Health)

Clinical Challenges of Pelvic Floor Disorders Management

edited by

Matteo Frigerio

submission deadline 20 Jan 2026 | 4 articles | Viewed by 5370 | Submission Open

Keywords: pelvic floor disorders; pelvic organ prolapse; urinary incontinence; surgery; diagnostics; pelvic pain; vulvodynia; urinary tract symptoms; mesh-related complications

(This special issue belongs to the Section Obstetrics & Gynecology)

Displaying special issue 401-450 on page 9 of 31.

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