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Clinical Advances in Minimally Invasive Urologic Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 639

Special Issue Editors


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Guest Editor
1. Unit of Urology, GVM—Saint Mary Hospital, 70121 Bari, Italy
2. Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, 70121 Bari, Italy
Interests: urology; uro-oncology; robotic surgery; laparoscopy; prostatectomy; nephrectomy; cystectomy

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Guest Editor
Division of Urology, Magna Graecia University of Catanzaro, Catanzaro, Italy
Interests: urology; uro-oncology; robotic surgery; laparoscopy; prostatectomy; nephrectomy; cystectomy

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Guest Editor
1. Department of Urology, University of L’Aquila, 67100 L’Aquila, Italy
2. Department of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples “Federico II”, 80131 Naples, Italy
Interests: urology; oncology; robotic surgery
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Special Issue Information

Dear Colleagues,

Minimally invasive surgery has undergone significant advancements in urology, fundamentally transforming patient care. These innovations, including laparoscopy, robotic-assisted surgery, and endourology, have redefined surgical approaches by offering patients less invasive alternatives, characterized by a reduction in postoperative discomfort, shorter hospital stays, and accelerated recuperation periods, especially when compared with traditional open surgeries. Through these techniques, urologists can execute more and more challenging procedures with precision while also minimizing tissue trauma. Consequently, the spectrum of treatable conditions using minimally invasive strategies, spanning from prostate cancer to urinary incontinence, has substantially expanded. As technology continues to progress and surgical expertise evolves, the horizon of urologic surgery holds promise for further enhancements using minimally invasive approaches. In this Special Issue, we welcome authors to submit papers on the clinical advancements in minimally invasive urologic surgery across the entire field of urological surgery.

Dr. Umberto Carbonara
Dr. Fabio Crocerossa
Dr. Savio Domenico Pandolfo
Guest Editors

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Keywords

  • urology
  • uro-oncology
  • uro-gynecology
  • robotic surgery
  • laparoscopy
  • robot-assisted
  • artificial intelligence

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Published Papers (1 paper)

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Research

12 pages, 2082 KiB  
Article
Prostate Artery Embolization (PAE) in the Treatment of Benign Prostatic Hyperplasia: A Case Series and Narrative Review
by Vincenzo Iossa, Ernesto Punzi, Savio Domenico Pandolfo, Gianluca Spena, Pierluigi Russo, Carlo Giulioni, Achille Aveta, Lorenzo Spirito, Giulio Lombardi and Vittorio Imperatore
J. Clin. Med. 2025, 14(11), 3775; https://doi.org/10.3390/jcm14113775 - 28 May 2025
Viewed by 263
Abstract
Background/Objectives: Prostatic artery embolization (PAE) has emerged as a minimally invasive alternative for treating lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH), particularly in high-risk surgical candidates. This study aims to evaluate the efficacy, safety, and clinical outcomes of PAE, [...] Read more.
Background/Objectives: Prostatic artery embolization (PAE) has emerged as a minimally invasive alternative for treating lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH), particularly in high-risk surgical candidates. This study aims to evaluate the efficacy, safety, and clinical outcomes of PAE, combining a retrospective case series with a narrative review of the literature. Methods: A single-center retrospective analysis was conducted on 10 patients aged ≥ 70 years with moderate-to-severe LUTS due to BPH who underwent PAE between January 2021 and January 2024. Inclusion criteria included IPSS > 18, Qmax < 12 mL/s, prostate volume > 45 cc, and resistance to medical therapy. Embolization was performed using 300–500 µm tris-acryl gelatin microspheres via the PErFecTED technique. Follow-up included IPSS, Qmax, prostate volume (PV), PSA levels, and complications. A narrative review of 18 studies (n = 1539 patients) was also conducted to contextualize findings. Results: Technical success was achieved in all patients (100%), and clinical success (IPSS reduction ≥ 50%) in 90%. At 12 months, the following significant improvements were observed: mean IPSS decreased from 24 to 12 (p < 0.0001), Qmax increased from 8.7 to 12.6 mL/s (p < 0.0001), PV reduced from 66.4 to 49.4 cc (p < 0.0001), and PSA from 5.0 to 3.4 ng/mL (p < 0.0001). Outcomes remained stable up to 36 months. Two patients developed transient post-procedural fever; no major complications were recorded. Conclusions: PAE is a safe and effective treatment for LUTS related to BPH, offering durable symptom relief and minimal morbidity, particularly in elderly and comorbid patients. While the evidence supports its role as an alternative to TURP, larger prospective trials are necessary to confirm its long-term efficacy and optimize patient selection. Full article
(This article belongs to the Special Issue Clinical Advances in Minimally Invasive Urologic Surgery)
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