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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Personalized Management of Chronic Obstructive Pulmonary Disease (COPD)

edited by

Athena Gogali

and Georgios Hillas

submission deadline 20 Feb 2026 | Viewed by 94 | Submission Open

Keywords: artificial intelligence; biologics; biomarkers; diagnostics; oscillometry; COPD pharmacotherapy; imaging

(This special issue belongs to the Section Respiratory Medicine)

Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges

edited by Vasiliki Gkalea and Despina Fotiou

submission deadline 20 Feb 2026 | Viewed by 94 | Submission Open

Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS

(This special issue belongs to the Section Hematology)

Clinical Advances in Sepsis and Septic Shock

edited by

Lucia Filippi

and Lorenzo Ghiadoni

submission deadline 20 Feb 2026 | Viewed by 89 | Submission Open

Keywords: sepsis-induced coagulopathy; endothelial dysfunction in sepsis; fluid balance in sepsis

(This special issue belongs to the Section Emergency Medicine)

New Insights into Management of Chronic Rhinosinusitis

edited by

Giandomenico Maggiore

submission deadline 20 Feb 2026 | Viewed by 79 | Submission Open

Keywords: chronic rhinosinusitis; management; surgery; minimally invasive surgery; surgical oncology; cancer surgery; skull base surgery; hoarseness; laryngeal neoplasms; laryngoscopy; general surgery; X-ray computed tomography

(This special issue belongs to the Section Otolaryngology)

Recent Advances in Gynecologic Surgery

edited by Adam Ostrzenski

submission deadline 20 Feb 2026 | Viewed by 68 | Submission Open

Keywords: gynecologic surgery; pelvic reconstruction surgery; female stress urinary incontinence surgery; cosmetic gynecology surgery; surgical meshes slings; native tissue

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Head and Neck Cancer Diagnostics and Treatment

edited by

Dustin A. Silverman

and Alice L. Tang

submission deadline 20 Feb 2026 | Viewed by 64 | Submission Open

Keywords: head and neck; reconstruction; free flap; surgical margin; biomarker; human papillomavirus (HPV); extranodal extension; immunotherapy; virtual surgical planning

(This special issue belongs to the Section Otolaryngology)

Mental Disorders, Cognitive Impairment and Dementia Among Older Adults

edited by

Agustín Aibar Almazán

submission deadline 21 Feb 2026 | 3 articles | Viewed by 4019 | Submission Open

Keywords: mental disorders; cognitive decline; dementia; older adults; mental health; exercise; physical function

(This special issue belongs to the Section Geriatric Medicine)

Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body

edited by

Valentin Haug

submission deadline 24 Feb 2026 | 3 articles | Viewed by 5390 | Submission Open

Keywords: reconstructive surgery; academic plastic surgery; research; social media in plastic surgery; breast surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Current and Emerging Treatment Options for Aortic Aneurysms

edited by Spyros Ioannis Papadoulas and

Vasileios Leivaditis

submission deadline 24 Feb 2026 | 1 articles | Viewed by 358 | Submission Open

Keywords: thoracic aortic aneurysms; abdominal aortic aneurysm; vascular surgery; cardiac surgery; treatment

(This special issue belongs to the Section Vascular Medicine)

Acute Respiratory Failure: Innovations and Clinical Insights

edited by

Gilda Cinnella

submission deadline 25 Feb 2026 | 3 articles | Viewed by 20851 | Submission Open

Keywords: ARF; mechanical ventilation; VILI; PSILI; NIV; HFNO; weaning; EIT; lung US

(This special issue belongs to the Section Intensive Care)

Interventional Pulmonology: Advances and Future Directions

edited by Martina Ferioli and Piero Candoli

submission deadline 25 Feb 2026 | 7 articles | Viewed by 11768 | Submission Open

Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging

(This special issue belongs to the Section Respiratory Medicine)

(Recent Advances) Treating Psychiatry Disorders in Children and Adolescents: From Theory to Practice: 2nd Edition

edited by

Pietro Muratori

and

Valentina Levantini

submission deadline 25 Feb 2026 | 5 articles | Viewed by 9622 | Submission Open

Keywords: intervention program; youth psychopathology; internalizing disorders; externalizing disorders; psychiatric disorders

(This special issue belongs to the Section Mental Health)

Advancing Pediatric Sports Medicine: Insights and Innovations

edited by Brian C. Lau

submission deadline 25 Feb 2026 | 4 articles | Viewed by 7614 | Submission Open

Keywords: sport surgery; patellar instability; early sport specialization; triplane fractures; pediatric sports medicine; orthopedic surgery; access to care; arthroscopic

(This special issue belongs to the Section Orthopedics)

Interventional and Surgical Treatment of Acute and Chronic Pancreatitis

edited by Chirag Desai

submission deadline 25 Feb 2026 | 5 articles | Viewed by 7374 | Submission Open

Keywords: pancreatitis treatment; endoscopic treatment; pancreatic surgery; Whipple; distal pancreatectomy; islet cell auto trans-plant; total pancreatectomy; TPIAT; laparoscopic treatment of pancreatitis; robotic surgery for pancreatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition

edited by

Joaquín Moya-Angeler

and

Francisco Forriol

submission deadline 25 Feb 2026 | 5 articles | Viewed by 7222 | Submission Open

Keywords: knee; knee replacement; knee arthroplasty; knee alignment technique; robotic knee arthroplasty

(This special issue belongs to the Section Orthopedics)

New Advances in Total Knee Arthroplasty

edited by

Carlo Biz

submission deadline 25 Feb 2026 | 4 articles | Viewed by 6779 | Submission Open

Keywords: artificial intelligence; bone tumors; knee joint; knee pain; knee replacement; knee surgery; orthopedic surgery; osteoarthritis; prognostic markers; radiological evaluation

(This special issue belongs to the Section Orthopedics)

Acute Coronary Syndromes: From Diagnosis to Treatment

edited by

Andreas Mitsis

and Christos Eftychiou

submission deadline 25 Feb 2026 | 3 articles | Viewed by 6044 | Submission Open

Keywords: acute coronary syndrome; diagnosis; biomarkers; interventional cardiology; imaging; pharmacotherapy; patient management; health systems; special populations; clinical trials

(This special issue belongs to the Section Cardiology)

New Advances in Keratoplasty

edited by Cristina Bovone

submission deadline 25 Feb 2026 | 3 articles | Viewed by 5862 | Submission Open

Keywords: lamellar keratoplasty; descemet stripping endothelial keratoplasty (DSAEK); descemet membrane endothelial keratoplasty (DMEK); deep anterior lamellar keratoplasty (DALK); keratoconus; corneal dystrophies; bullous keratopathy; anterior segment OCT

(This special issue belongs to the Section Ophthalmology)

Advances in the Management of Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

edited by Ahmed Abuzaid

submission deadline 25 Feb 2026 | 3 articles | Viewed by 4783 | Submission Open

Keywords: cardiac amyloidosis; hypertrophic cardiomyopathy; left ventricular hypertrophy; non-invasive cardiac imaging; heart failure; clinical manifestations

(This special issue belongs to the Section Cardiology)

New Insights into Cardiorenal Metabolic Syndrome

edited by

Caterina Carollo

submission deadline 25 Feb 2026 | 3 articles | Viewed by 4556 | Submission Open

Keywords: cardiorenal medicine; diabetes; chronic renal failure; heart failure; cardiorenal syndrome; nephrocardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Alzheimer’s Disease and Related Disorders: Recent Advances in Prevention, Diagnosis and Therapy

edited by

Daniel H. S. Silverman

submission deadline 25 Feb 2026 | 2 articles | Viewed by 3580 | Submission Open

Keywords: cognition; prodromal; Alzheimer’ s; Alzheimer; dementia; mild cognitive impairment; mild decline in cognition; disease-modifying; amyloid; tau; neuroinflammation; biomarkers; neuroimaging; PET; PET/CT; PET/MRI

(This special issue belongs to the Section Clinical Neurology)

Obesity Surgery—State of the Art

edited by Anna Casajoana

submission deadline 25 Feb 2026 | 2 articles | Viewed by 3217 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; diabetes mellitus type 2; GLP-1

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Recent Advances in Reconstructive Oral and Maxillofacial Surgery

edited by

Luciano Maria Catalfamo

submission deadline 25 Feb 2026 | 2 articles | Viewed by 3094 | Submission Open

Keywords: oral surgery; maxillofacial surgery; new technologies; free flap; reconstructive surgery; artificial intelligence

(This special issue belongs to the Section General Surgery)

Clinical Aspects and Outcomes in Contemporary Colorectal Surgery

edited by

Lior Segev

submission deadline 25 Feb 2026 | 3 articles | Viewed by 2894 | Submission Open

Keywords: colorectal surgery; colorectal cancer; Crohn’ s disease; ulcerative colitis; coloproctology; minimally invasive surgery

(This special issue belongs to the Section General Surgery)

Clinical Research in Palliative Care

edited by Cosimo Chelazzi

submission deadline 25 Feb 2026 | 2 articles | Viewed by 2589 | Submission Open

Keywords: cancer palliative care; total pain; advanced care planning; spiritual care; financial toxicity; cancer-related pain

(This special issue belongs to the Section Clinical Rehabilitation)

Updates in the Orthopedic Management of Foot Disorders: 2nd Edition

edited by

Carlo Biz

and

Pietro Ruggieri

submission deadline 25 Feb 2026 | 2 articles | Viewed by 2364 | Submission Open

Keywords: foot pathologies; diabetic feet; forefoot deformities; oncology surgery; foot tumors; minimally invasive surgery; percutaneous surgery; foot joint arthroscopy; stress fractures

(This special issue belongs to the Section Orthopedics)

Innovations in Advanced Echocardiography

edited by Rebecca T. Hahn and Alexandros Papachristidis

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1577 | Submission Open

Keywords: advanced echocardiography; ultrafast ultrasound; contrast echocardiography; subharmonic aided pressure estima-tion; artificial intelligence; 3D echocardiography

(This special issue belongs to the Section Cardiology)

Non-Small-Cell Lung Cancer: Screening, Diagnosis and Treatment Options in the AI and Omics Era

edited by Miljana Tanić

submission deadline 25 Feb 2026 | 2 articles | Viewed by 1327 | Submission Open

Keywords: lung cancer; NSCLC; radiomics; digital pathology; electronic health records; tumor profiling; AI; machine learning; deep learning; liquid biopsy; early detection; diagnosis; prognosis; therapy; biomarkers; management

(This special issue belongs to the Section Respiratory Medicine)

Helicobacter pylori-Associated Intestinal Diseases and Beyond

edited by

Antonio Facciorusso

submission deadline 25 Feb 2026 | 1 articles | Viewed by 992 | Submission Open

Keywords: IBD; Hp; stomach; celiac disease; diverticulosis; diverticulitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Clinical Pharmacology Based on Pharmacokinetics

edited by

Magdalena Cuciureanu

Cristina Ghiciuc

and

Nina Filip

submission deadline 25 Feb 2026 | Viewed by 964 | Submission Open

Keywords: PK/PD modeling; dose optimization; clinical decision-making tools; therapeutic drug monitoring; personalized medicine

(This special issue belongs to the Section Pharmacology)

Hospital-Acquired Infections: Evolving Threats and Epidemiological Insights

edited by

Amir Nutman

submission deadline 25 Feb 2026 | 1 articles | Viewed by 759 | Submission Open

Keywords: hospital-acquired infections; healthcare-associated infections; antimicrobial resistance; multidrug-resistant organisms (MDRO); infection prevention and control; outbreak investigation; patient safety; healthcare epidemiology

(This special issue belongs to the Section Infectious Diseases)

Clinical Advances of Retinal and Vitreous Diseases: Current Status and Prospect

edited by Lorenzo De Angelis, Francesco Barca and Stanislao Rizzo

submission deadline 25 Feb 2026 | 1 articles | Viewed by 496 | Submission Open

Keywords: vitreoretinal surgery; retinal multimodal imaging; gene therapy; retinal diseases; age-related macular degeneration; vascular retinal disease; imaging technologies in ophthalmology

(This special issue belongs to the Section Ophthalmology)

Application of Echocardiography in Clinical Practice

edited by

Shemy Carasso

submission deadline 25 Feb 2026 | 1 articles | Viewed by 288 | Submission Open

Keywords: echocardiography; three-dimensional imaging; mechanical imaging; strain; artificial intelligence; interventional echocardiography; POCUS; hand-held echocardiography; cancer therapy and cardiotoxicity

(This special issue belongs to the Section Cardiovascular Medicine)

Evidence-Based Physiotherapy: Prospects and Challenges

edited by Roman Nowobilski and

Maciej Płaszewski

submission deadline 25 Feb 2026 | Viewed by 241 | Submission Open

Keywords: evidence-based practice; physiotherapy; critique; certainty of evidence; clinical practice guidelines; implementa-tion; clinical settings; clinical practice; clinical processing

(This special issue belongs to the Section Clinical Rehabilitation)

Advancing Clinical Medicine Through Artificial Intelligence (AI) and Digital Technology: 2nd Edition

edited by

Antonio Jorge Forte

Syed Ali Haider

and

Mark Lifson

submission deadline 25 Feb 2026 | Viewed by 240 | Submission Open

Keywords: artificial intelligence; clinical medicine; medical imaging; precision medicine; clinical decision support systems; patient care; healthcare practices; early disease detection; patient outcomes

(This special issue belongs to the Section Intensive Care)

Clinical Research Progress in Diabetes and Cardiovascular Diseases

edited by

Ken-ichi Aihara

submission deadline 25 Feb 2026 | Viewed by 148 | Submission Open

Keywords: diabetes; cardiovascular diseases; risk factor; vascular function; diagnosis; treatment

(This special issue belongs to the Section Cardiovascular Medicine)

Plastic and Reconstructive Surgery: Clinical Advances and Future Opportunities

edited by Rami S Kantar

submission deadline 25 Feb 2026 | Viewed by 128 | Submission Open

Keywords: plastic surgery; reconstructive surgery; cleft lips; palates; post-traumatic reconstruction; facial transplantation; craniofacial surgery; cleft surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Current Advances and Future Perspectives of Sepsis and Septic Shock

edited by Filippo Mearelli and Gianni Biolo

submission deadline 25 Feb 2026 | Viewed by 117 | Submission Open

Keywords: sepsis; epidemiology; biomarkers; diagnosis; predictive models; prognostication

(This special issue belongs to the Section Emergency Medicine)

Segmentectomy and Lobectomy in Early-Stage Lung Cancer Management

edited by Yujin Kudo

submission deadline 25 Feb 2026 | Viewed by 114 | Submission Open

Keywords: lung cancer; segmentectomy; lobectomy; thoracic surgery; early-stage NSCLC; oncologic outcomes; pulmonary function; surgical planning

(This special issue belongs to the Section Respiratory Medicine)

Allergic and Eosinophilic Diseases: Diagnosis, Treatment and Management (Second Edition)

edited by Aikaterini Detoraki

submission deadline 25 Feb 2026 | Viewed by 112 | Submission Open

Keywords: allergy; eosinophilic diseases; immunology; clinical immunology; asthma; diagnosis; treatment; management

(This special issue belongs to the Section Immunology & Rheumatology)

Spinal Surgery: Recent Advances and Future Perspectives

edited by

Yoshiharu Kawaguchi

submission deadline 25 Feb 2026 | Viewed by 111 | Submission Open

Keywords: spine surgery; diagnostic technology; AI; images; biomarkers; genetics; robotic surgery; minimum invasive surgery; pain control; VR

(This special issue belongs to the Section Orthopedics)

Clinical Updates of Diagnosis and Treatment in Chronic Kidney Disease (CKD)

edited by

Juan F. Navarro-González

, Carmen Mora-Fernández and

Javier Donate-Correa

submission deadline 25 Feb 2026 | Viewed by 107 | Submission Open

Keywords: CKD; CKD progression; biomarkers; disease-modifying treatments; diabetic kidney disease; cardiorenal disease; glomerunephritis; genetic kidney diseases

(This special issue belongs to the Section Nephrology & Urology)

Clinical Update on the Diagnosis and Treatment of Heart Failure

edited by Giulia Nardi and Alessio Mattesini

submission deadline 26 Feb 2026 | 5 articles | Viewed by 12604 | Submission Open

Keywords: ejection fraction; acute heart failure; multidisciplinary management; right heart failure; left ventricle remodeling systems; HF percutaneous treatment; pharmacotherapy; HF prevention; cardiomyopathies

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Arrhythmia Diagnosis and Management

edited by Zoltán Csanádi

submission deadline 26 Feb 2026 | 7 articles | Viewed by 8999 | Submission Open

Keywords: catheter ablation; atrial fibrillation; ventricular tachycardia; conduction system pacing; cardiac resynchronization; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Pancreatic Cancer: Novel Strategies of Diagnosis and Treatment

edited by

Camelia Cristina Diaconu

and

Gina Gheorghe

submission deadline 26 Feb 2026 | 2 articles | Viewed by 2534 | Submission Open

Keywords: pancreatic cancer; chronic pancreatitis; pancreatic intraepithelial neoplasia; gastroenterology; clinical innovative diagnostic; clinical treatment strategies

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Orthodontics: State of the Art and Perspectives

edited by

Camelia Szuhanek

and

Irina Nicoleta Zetu

submission deadline 27 Feb 2026 | 9 articles | Viewed by 13051 | Submission Open

Keywords: orthodontics; digital orthodontics; intraoral scanners; facial scanners; treatment planning; interdisciplinary treatment; orthodontic implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Unraveling Myopia: Current Science, Clinical Impact, and Future Horizons

edited by Neeraj K Singh and Pablo De Gracia

submission deadline 27 Feb 2026 | 2 articles | Viewed by 2091 | Submission Open

Keywords: accommodation; contact lenses; ophthalmic lenses; myopia progression; epidemiology; myopia control interventions; pharmaceutical treatments; environmental and behavioral risk factors; imaging innovations in myopia

(This special issue belongs to the Section Ophthalmology)

Harnessing Photobiomodulation Light for Therapeutic or Prevention of Human Diseases

edited by

Reem Hanna

submission deadline 28 Feb 2026 | 6 articles | Viewed by 25443 | Submission Open

Keywords: neurorehabilitation; supportive care for cancer; reproductive health; dental and oral diseases; viral and bacterial diseases; wound care; dermatology; sports rehabilitation; bone and musculoskeletal diseases; PBM mechanism; ophthalmology; stem cells and regenerative medicine; pain and addiction management; PBM-tissue interaction

Advances in Child Neurology

edited by

Giuseppina Sgandurra

and

Marco Carotenuto

submission deadline 28 Feb 2026 | 6 articles | Viewed by 17030 | Submission Open

Keywords: pediatric neurological disorders; pediatric sleep disorders; pediatric epilepsy; autoimmune encephalitis; pediatric acute-onset neuropsychiatric syndrome (PANS); pediatric headaches; RASopathies; neurogenetic disorders; developmental coordination disorder (DCD); pedaitric neurological rehabilitation; AI application for diagnosis and therapeutic management of pediatric neurological diseases

(This special issue belongs to the Section Clinical Pediatrics)

Headache Disorders: New Advances in Management and Treatment Strategies: 2nd Edition

edited by

Andreas A. Argyriou

Emmanouil V. Dermitzakis

and

Vikelis Michail

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1950 | Submission Open

Keywords: headache; migraine; cluster headache; tension-type headache; post-traumatic headache; calcitonin gene-related peptide; monoclonal antibodies; preventive therapy; acute treatment; pathophysiology; neuromodulation; pain management; drug development; gepants; ditan

(This special issue belongs to the Section Clinical Neurology)

Displaying special issue 751-800 on page 16 of 31.

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