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Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition
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Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 1134

Special Issue Editors

Dr. Joaquín Moya-Angeler

E-Mail Website
Guest Editor
1. Department of Orthopaedic Surgery and Traumatology, Hospital General Universitario Reina Sofía, 30003 Murcia, Spain
2. Instituto de Cirugía Avanzada de la Rodilla (ICAR), 30005 Murcia, Spain
Interests: knee preservation; knee replacement; osteotomies; sports medicines; ACL reconstruction; patellofemoral disorders; trochlear dysplasia; meniscus
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Francisco Forriol

E-Mail Website
Guest Editor
School of Medicine, Universidad San Pablo CEU, Ctra. Boadilla del Monte, Km. 5 300, 28925 Alcorcon, Madrid, Spain
Interests: knee surgery; orthopedic surgery; muscle; bone; limb salvage
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This is the second edition of the Special Issue “Knee Arthroplasty Surgery: Management and Future Opportunities ” (https://www.mdpi.com/journal/jcm/special_issues/C15R9891KN).

We find ourselves standing at a pivotal moment in the realm of knee arthroplasty surgery. For nearly half a century, the landscape of this surgical field has seen limited transformations. However, in recent times, we have witnessed a surge of innovations propelled by the development of more advanced techniques and implants. Our early endeavors revolved around mitigating severe complications and ensuring the durability of implants through the refinement of bearing surfaces, enhanced biological fixations, precise instrumentation systems, and less invasive approaches. Yet, it is equally evident that the once universally accepted principles now demand a more evidence-based evaluation.

This profound transformation currently underway focuses on the integration of personalized medicine principles into knee arthroplasty. Clinicians and researchers now champion diverse philosophies of component alignment and knee prosthesis biomechanics. These philosophies acknowledge the uniqueness of each joint, advocating for a tailored approach to suit individual patients. Our ultimate goal is to enhance arthroplasty longevity and functionality, elevate each patient's health-related quality of life, and achieve a sense of normalcy in the operated knee. We aim for our patients to forget they underwent surgery.

With these changes, we have witnessed an abundance of data and insights. This Special Issue endeavors to serve as an inclusive platform for disseminating these innovative contributions and expanding our knowledge.

Topics to be explored include:

  • New concepts in alignment;
  • The integration of technology in knee arthroplasty;
  • Advancements in customized surgery;
  • Exploring extended reality and immersive technologies;
  • Defining the limits and unveiling future challenges.

We invite you all to be part of this transformative journey. Together, let us delve into the forefront of knee arthroplasty, redefining the landscape of this discipline and improving the lives of our patients.

Dr. Joaquín Moya-Angeler
Prof. Dr. Francisco Forriol
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • knee
  • knee replacement
  • knee arthroplasty
  • knee alignment technique
  • robotic knee arthroplasty

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Related Special Issue

Published Papers (3 papers)

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14 pages, 977 KiB  
Article
Same but Different? Exploring the Role of Patient-Reported Outcome Measures and Clinician-Reported Outcome Measures in Postoperative Knee and Hip Arthroplasty Rehabilitation
by Alexandra Unger, Ferdinand Prüfer, Špela Matko, Michael J. Fischer and Vincent Grote
J. Clin. Med. 2025, 14(7), 2322; https://doi.org/10.3390/jcm14072322 - 28 Mar 2025
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Abstract
Background/Objectives: Patient-reported outcome measures (PROMs) and clinician-reported outcome measures (CROMs) are used in orthopaedic rehabilitation to evaluate patients’ health status and recovery. However, controversy still exists regarding their relevance and validity. This evaluation was conducted to assess the effectiveness and role of [...] Read more.
Background/Objectives: Patient-reported outcome measures (PROMs) and clinician-reported outcome measures (CROMs) are used in orthopaedic rehabilitation to evaluate patients’ health status and recovery. However, controversy still exists regarding their relevance and validity. This evaluation was conducted to assess the effectiveness and role of PROMs and CROMs in the orthopaedic rehabilitation outcome of patients who have undergone either total knee arthroplasty or hip arthroplasty. Methods: Outcome measures of 409 patients (68.3 ± 9.3 years; 34.2% male) with total knee arthroplasty and 308 patients (68.1 ± 10.6 years; 36.3% male) with total hip arthroplasty (control group) were assessed at baseline and after 21 days of inpatient rehabilitation. Effect sizes and correlations were analysed as they related to the use of PROMs and CROMs. To reduce statistical distortions caused by ceiling effects, we used a performance score (T2D) relying on two scores taken at the beginning and end of rehabilitation. Results: Large effect sizes (d > 0.97) for CROMs and medium effect sizes (d ≥ 0.65) for PROMs were observed in both groups. The standardised mean difference across all outcomes was 0.83 ± 0.59. PROMs worsened in 13.1% of all patients, while almost no patients showed a deterioration in CROMs. Correlations were highest between the Timed Up and Go and the Health Assessment Questionnaire scores (ρ > 0.45). Conclusions: Different and complementary assessment modalities of PROMs and CROMs serve as valuable clinical tools, providing a valid basis for interpreting patients’ health outcomes. Full article
(This article belongs to the Special Issue Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition)
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12 pages, 3008 KiB  
Article
Relationship Between Coronal Plane Alignment of the Knee Phenotypes and Distal Femoral Rotation
by Vicente J. León-Muñoz, José Hurtado-Avilés, Fernando Santonja-Medina, Francisco Lajara-Marco, Mirian López-López and Joaquín Moya-Angeler
J. Clin. Med. 2025, 14(5), 1679; https://doi.org/10.3390/jcm14051679 - 1 Mar 2025
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Abstract
Background: The coronal plane alignment of the knee (CPAK) classification categorises nine phenotypes based on constitutional limb alignment and joint line obliquity and can be used in healthy and arthritic knees. In total knee arthroplasty surgery, some morphological variables in planes other than [...] Read more.
Background: The coronal plane alignment of the knee (CPAK) classification categorises nine phenotypes based on constitutional limb alignment and joint line obliquity and can be used in healthy and arthritic knees. In total knee arthroplasty surgery, some morphological variables in planes other than the coronal plane are particularly interesting. One example is the distal femoral rotation. Our study aimed to search for relationships between phenotypes based on CPAK classification and distal femoral rotation. Methods: Data from 622 cases in 535 osteoarthritic patients who underwent primary total knee arthroplasty were retrospectively analysed. Computed tomography imaging was employed to ascertain the mechanical lateral distal femoral angle, the mechanical medial proximal tibial angle, and the distal femoral rotation (quantified using the condylar twist angle). Results: The variables were perfectly uncorrelated according to the regression equations, with a Coefficient of Determination of 0.0608 for the condylar twist angle. Upon visualising the condylar twist angle function using a contour map or surface curves with low interpolation, it became evident that the data did not follow any discernible pattern. Employing ANOVA, we found some statistically significant differences between the distributions of the CPAK groups for the condylar twist angle (F = 5.81; p < 0.001). Conclusions: Our study found no relevant relationships between coronal plane alignment, according to the CPAK classification, and the distal femoral rotation in the sample population studied. Perhaps the stratification of the CPAK groups (i.e., a purely arithmetical aspect) hides possible relationships between the coronal and the axial planes. Full article
(This article belongs to the Special Issue Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition)
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Other

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11 pages, 1178 KiB  
Perspective
How New Technologies Will Transform Total Knee Arthroplasty from a Singular Surgical Procedure to a Holistic Standardized Process
by Elliot Sappey-Marinier, Thais Dutra Vieira, Axel Schmidt, Tarik Aït Si Selmi and Michel Bonnin
J. Clin. Med. 2025, 14(9), 3102; https://doi.org/10.3390/jcm14093102 - 30 Apr 2025
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Abstract
Many new technologies focused mainly on improving surgical accuracy were first developed in total knee arthroplasty and have not yet shown significant value. These non-significant clinical improvements could potentially be explained by an inadequate target. In this current concept paper, the authors will [...] Read more.
Many new technologies focused mainly on improving surgical accuracy were first developed in total knee arthroplasty and have not yet shown significant value. These non-significant clinical improvements could potentially be explained by an inadequate target. In this current concept paper, the authors will describe how artificial intelligence (AI), robotic-assisted surgery, and custom implants allow the definition of new targets and the standardization of the TKA process. As paradoxical as it may be, new technologies in TKA will allow for better standardization in the overall way in which this procedure is carried out. Achieving this goal can be accomplished by incorporating AI-driven tools into the medical field. These tools are intended to enhance decision making, refine surgical planning, and increase the precision and consistency of surgical procedures. Moreover, custom implants with personalized alignment, beyond restoring native anatomy, will define new targets and standardize the whole TKA process. Full article
(This article belongs to the Special Issue Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition)
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