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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bioinspired and Emerging Functionalized Nanostructures for Precision Drug Delivery

edited by

Adelina-Gabriela Niculescu

and

Alexandra Catalina Birca

submission deadline 25 Dec 2026 | 1 articles | Viewed by 2184 | Submission Open

Keywords: nanostructured materials; nanobiomaterials; nanocomposites; drug delivery systems; targeted therapies; controlled release; responsive functionalities; theranostics; biomedical applications; therapeutic innovations; bioinspired nanostructures; personalized medicine

(This special issue belongs to the Section Molecular Nanoscience)

Atherosclerosis and Comorbidities: From Molecular Pathogenesis to Diagnosis and Therapeutic Targets

edited by

Alexandr Ceasovschih

Victoriţa Şorodoc

and

Yusuf Ziya Şener

submission deadline 25 Dec 2026 | 1 articles | Viewed by 2140 | Submission Open

Keywords: atherosclerosis; comorbidities; lipidology; inflammation; obesity; arterial stiffness; vascular remodeling; cardiovascular risk; cardiovascular diseases; targeted therapies; lifestyle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Gene, Genomics, and Molecular Breeding in Cruciferae Plants (3rd Edition)

edited by

Maoteng Li

submission deadline 25 Dec 2026 | 3 articles | Viewed by 2112 | Submission Open

Keywords: Cruciferae plants; genome analysis; genetic dissection; gene function; molecular breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Preimplantation Genetic Testing in Assisted Reproductive Technologies

edited by

Sung Tae Kim

submission deadline 25 Dec 2026 | 1 articles | Viewed by 2105 | Submission Open

Keywords: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Electrochemical Nanomaterials for Energy and Catalysis

edited by

Sankar Sekar

submission deadline 25 Dec 2026 | 1 articles | Viewed by 2022 | Submission Open

Keywords: advanced micro- and nanomaterials for electrochemical applications; electrochemical energy storage; electrocatalysis; photoelectrochemical water splitting; electrochemical sensors; supercapacitor; batteries; nanocomposites and functionalized materials; energy storage and conversion application; natural resources-based materials

(This special issue belongs to the Section Molecular Nanoscience)

Bioactive Molecules in Infection and Toxicity: Antimicrobial Peptides and Drug-Induced Damage in Disease Models

edited by

Oleksii Skorokhod

submission deadline 25 Dec 2026 | 1 articles | Viewed by 2014 | Submission Open

Keywords: antimicrobial peptides (AMPs); infectious diseases; drug-induced toxicity; disease models; therapeutic strategies; drug delivery systems

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research and Immune Landscape of Breast Cancer

edited by

Robson Monteiro

submission deadline 25 Dec 2026 | 2 articles | Viewed by 1796 | Submission Open

Keywords: breast cancer; immune landscape; single-cell analysis; omics; therapy resistance; metastasis

(This special issue belongs to the Section Molecular Immunology)

Gut Microbiota-Derived Metabolites in Human Health and Disease

edited by Zeneng Wang

submission deadline 25 Dec 2026 | 2 articles | Viewed by 1759 | Submission Open

Keywords: microbiome; microbiota; gut; metabolomics; health; disease; inflammation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Insights into Immunodeficiency and Immunotherapy in Multiple Myeloma

edited by

Marjorie Pick

and

Eyal Lebel

submission deadline 25 Dec 2026 | 2 articles | Viewed by 1542 | Submission Open

Keywords: multiple myeloma; plasma cells; monoclonality; immunodeficient

(This special issue belongs to the Section Molecular Immunology)

The Role of Complement Regulation in Kidney Disease

edited by Jasmina Marković Lipkovski

submission deadline 25 Dec 2026 | 1 articles | Viewed by 1485 | Submission Open

Keywords: complement system; kidney disease; glomerulonephritis; C3 glomerulopathy; membranous nephropathy; complement regulation; innate immunity; molecular pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Plant Biotechnology: From Pathogen Diagnostics to Disease Management

edited by

Abdul Kader Jailani Amirudeen

submission deadline 25 Dec 2026 | 1 articles | Viewed by 1432 | Submission Open

Keywords: plant pathogens; diagnostic; isothermal; biosensor; RNAi; CRISPRi; QTL mapping; GWAS; MAS or MABC

(This special issue belongs to the Section Molecular Plant Sciences)

Stem Cells for Biomedical Applications

edited by

Sorina Dinescu

submission deadline 25 Dec 2026 | 1 articles | Viewed by 1361 | Submission Open

Keywords: stem cells biology; stem cells differentiation; stem cell-based regenerative therapies; stem cells exosomes; personalized medicine; stem cell-based 3D models

(This special issue belongs to the Section Molecular Biology)

Viral Infections and Viral Pathogenesis

edited by

Shymaa E. Bilasy

submission deadline 25 Dec 2026 | 1 articles | Viewed by 1309 | Submission Open

Keywords: viral pathogenesis; viral– host interactions; viral persistence; long COVID; molecular virology; immune dysregulation; diagnosis; vaccines; oncoviruses; antiviral and gene therapy

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanism of Sympathetic Nerves in Cardiovascular Diseases and Cancer

edited by

Yutang Wang

submission deadline 25 Dec 2026 | Viewed by 1304 | Submission Open

Keywords: sympathetic nerve activity; adrenergic receptors; renal denervation; heart disease; stroke; atherosclerosis; hypertension; diabetes; metabolic syndrome; cancer

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Ophthalmic Diseases

edited by

Alicja Forma

submission deadline 25 Dec 2026 | 1 articles | Viewed by 1218 | Submission Open

Keywords: environmental hazards; ophthalmic diseases; molecular mechanisms; risk factors; disease prevention; oxidative stress; biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug Treatment for Bacterial Infections: 2nd Edition

edited by Janusz Madaj

submission deadline 25 Dec 2026 | 1 articles | Viewed by 1151 | Submission Open

Keywords: bacterial infection; antibiotic-resistant bacteria; new agents in the treatment of bacterial infections; optimization of the use of already registered drugs; single antibacterial agents; combined antibacterial agents; new drug forms

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms of Reproduction and Reproductive Diseases

edited by

Sung Tae Kim

submission deadline 25 Dec 2026 | 1 articles | Viewed by 1146 | Submission Open

Keywords: reproduction; implantation; fertilization; gametogenesis; preimplantation genetic testing; in vitro fertilization; infertility; miscarriage; reproductive aging; endometriosis; premature ovarian failure; menopause; preeclampsia; preterm birth; placenta; testis; azoospermia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Psychobiotics as Next-Generation Probiotics: A Holistic Approach to Mental Health and Gut–Brain Axis Modulation

edited by

Edyta Juszczuk-Kubiak

submission deadline 25 Dec 2026 | Viewed by 869 | Submission Open

Keywords: probiotics; gut microbiota; gut– brain axis; mental health

(This special issue belongs to the Section Molecular Biology)

Drug and Non-Drug Treatment of Cerebral Diseases

edited by

Silvia Carloni

submission deadline 25 Dec 2026 | 1 articles | Viewed by 827 | Submission Open

Keywords: cerebral diseases; cerebral ischemia; neonatal hypoxic-ischemic encephalopathy (HIE); neuroprotection; therapeutic hypothermia; neurorehabilitation; oxidative stress; stem cell therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Modern Approaches in Regenerative Therapy

edited by

Daria Chudakova

and

Vladimir P. Baklaushev

submission deadline 25 Dec 2026 | 1 articles | Viewed by 765 | Submission Open

Keywords: regenerative therapy; regeneration; neuroregeneration; cell reprogramming; cell therapy; regenerative bio-scaffolds; extracellular vesicles; mesenchymal stromal/stem cells (MSCs); cell differentiation; omics technologies

(This special issue belongs to the Section Molecular Biology)

Epilepsy: Molecular Neuropharmacology, Calcium Signalling, Neuroinflammation, and Drug Discovery

edited by Maria F. Cano-Abad

submission deadline 25 Dec 2026 | 1 articles | Viewed by 763 | Submission Open

Keywords: epilepsy receptor pharmacology; neurotransmitter receptor modulation; calcium signaling and homeostasis; therapeutic targets in epilepsy; GABAergic and glutamatergic systems

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Clinical Advances in Ophthalmic Inflammation, Infection, and Degeneration

edited by Hyun Jin Shin

submission deadline 25 Dec 2026 | Viewed by 693 | Submission Open

Keywords: ophthalmic inflammation; ocular infection; ocular degeneration; molecular mechanisms; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Host Immunity and Viral Evolution: Dissecting the Molecular Variations of Viral Genomes

edited by Maria Victoria Preciado

submission deadline 25 Dec 2026 | Viewed by 689 | Submission Open

Keywords: virus evolution; immune response; host– virus interaction; vaccine design; antiviral design; virus emergence and reemergence; bioinformatics; immunoinformatics

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Molecular Targets for Treatment and Drug Delivery in Tumors: 2nd Edition

edited by

Emily Capone

submission deadline 25 Dec 2026 | 1 articles | Viewed by 688 | Submission Open

Keywords: targeted therapy; tumor; molecular target; drug delivery; drug design

(This special issue belongs to the Section Molecular Oncology)

Plant Extracts and Their Biological Activities: In Vitro and In Vivo

edited by

Ângelo Luís

submission deadline 25 Dec 2026 | 1 articles | Viewed by 674 | Submission Open

Keywords: plant extracts; bioactive compounds; molecular mechanisms; in vitro and in vivo studies; biological activities

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advanced Research on Comparative Reproductive Physiology

edited by

Heriberto Rodriguez-Martinez

and

Manuel Álvarez-Rodríguez

submission deadline 25 Dec 2026 | 1 articles | Viewed by 672 | Submission Open

Keywords: andrology; sperm; oocyte; gamete interactions; reproductive morphology; reproductive endocrinology; omics; epigenetics; pregnancy; all animal species

(This special issue belongs to the Section Molecular Biology)

Advancements in Antioxidant Molecules: From Discovery to Therapeutic Applications

edited by

Davide Moi

submission deadline 25 Dec 2026 | 1 articles | Viewed by 653 | Submission Open

Keywords: antioxidants; natural products; small molecules; polyphenols; reactive oxygen species; drug discovery; oxidative stress; apoptosis; target validation

(This special issue belongs to the Section Molecular Pharmacology)

Identification of Predictive Molecular Markers for Cancer Progression, Response to Therapy, and Disease Outcome

edited by

Shadma Fatima

submission deadline 25 Dec 2026 | 1 articles | Viewed by 651 | Submission Open

Keywords: predictive biomarkers; cancer progression; therapy response; molecular signatures; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Perineuronal Nets and Fear Memories Erasure: State of the Art and Future Directions

edited by

Andrea Poli

submission deadline 25 Dec 2026 | Viewed by 535 | Submission Open

Keywords: perineuronal nets (PNNs); extracellular matrix (ECM); fear erasure; traumatic memories; PTSD; translation research; clinical treatment; therapeutical strategies

(This special issue belongs to the Section Molecular Neurobiology)

HPV Infection and Immune Escape Mechanisms

edited by

Vittorio Unfer

and Elisa Lepore

submission deadline 25 Dec 2026 | Viewed by 485 | Submission Open

Keywords: HPV; persistence; natural molecules; vaccination; genotypes; anal infection; oral infection; co-infection

(This special issue belongs to the Section Molecular Immunology)

Advances in Growth, Development and Secondary Metabolism in Microorganisms

edited by

Francisco Jose Fernandez

and

Ramón O. García-Rico

submission deadline 25 Dec 2026 | Viewed by 482 | Submission Open

Keywords: secondary metabolites; signal transduction; molecular regulation; microbial growth; morphogenesis; microbial metabolites; biotechnological applications; omics technologies

(This special issue belongs to the Section Molecular Microbiology)

Biomolecular Stratification in Antiphospholipid Syndrome

edited by

Cristina Belizna

submission deadline 25 Dec 2026 | 1 articles | Viewed by 445 | Submission Open

Keywords: antiphospholipid syndrome; antiphospholipid; stratification; biomolecular; risk stratification; classification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Autophagy and Apoptosis in Mammal Cells

edited by Kaja Urbańska and Anna Litwiniuk

submission deadline 25 Dec 2026 | Viewed by 436 | Submission Open

Keywords: autophagy; apoptosis; cellular homeostasis; intra- and intercellular crosstalk; autophagic cell death; programmed cell death

(This special issue belongs to the Section Molecular Biology)

Latest Research in Neuroinflammation

edited by Reza Khorooshi

submission deadline 25 Dec 2026 | Viewed by 412 | Submission Open

Keywords: neuroinflammation; central nervous system disorders; neuroimmune interactions; inflammation and neurodegeneration; therapeutic strategies in neurology

(This special issue belongs to the Section Molecular Neurobiology)

Research Advances in Plant Interactions with Bacteria and Fungi: From Molecular to Ecological Perspectives

edited by

Jessie Fernandez

submission deadline 25 Dec 2026 | 1 articles | Viewed by 398 | Submission Open

Keywords: plant-microbe interactions; plant-bacteria interactions; plant-fungi interactions; biocontrol; beneficial microbes; endophytes; microbiome; plant growth-promoting microbes; synthetic microbial communities

(This special issue belongs to the Section Molecular Plant Sciences)

Gene Delivery in Cancer Therapy: Next-Generation Platforms and Translational Advances

edited by

Ksenija Božinović

submission deadline 25 Dec 2026 | Viewed by 379 | Submission Open

Keywords: gene delivery; gene therapy; viral vectors; non-viral vectors; lipid nanoparticles; extracellular vesicles; mRNA therapeutics; CRISPR/Cas genome editing; tumor microenvironment; translational oncology

(This special issue belongs to the Section Molecular Oncology)

Bioactive Food Components in Human Health

edited by

Kamila Rachwał

and Klaudia Gustaw

submission deadline 25 Dec 2026 | 1 articles | Viewed by 368 | Submission Open

Keywords: bioactive compounds; functional food; phytochemicals; bioactive peptides; health-promoting foods; food chemistry; polyphenols; natural products; human health; prebiotic compounds; bioavailability; nutraceuticals; bioaccessibility

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Biology, Genetics, Diagnosis, Management and Therapy of Dermatological Diseases

edited by

Elisa Molinelli

and Corrado Tagliati

submission deadline 25 Dec 2026 | Viewed by 350 | Submission Open

Keywords: genodermatoses; hydradenitis suppurativa; inflammatory dermatoses; metabolic disorders; infections; esthetic medicine; neoplastic diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Characterization and Engineering of Functional Nanomaterials

edited by

Paramasivan Sivaprakash

and Shanmugam Vignesh

submission deadline 25 Dec 2026 | Viewed by 349 | Submission Open

Keywords: functional nanomaterials; molecular-level engineering; engineered materials; materials characterization; energy and environmental applications; materials design and performance

(This special issue belongs to the Section Molecular Nanoscience)

Decoding the Pediatric Brain Tumor Microenvironment: A Molecular Perspective

edited by

Samuele Tardito

submission deadline 25 Dec 2026 | Viewed by 346 | Submission Open

Keywords: pediatric brain tumor; precision immunotherapy; pediatric neuro-oncology; tumor microenvironment (TME); single-cell RNA sequencing; whole transcriptomics; mass spectrometry-based proteomics; mass cytometry; cellular and molecular architecture; organoid

(This special issue belongs to the Section Molecular Oncology)

Molecular Biomarkers for Assessing Marine Ecosystem Health

edited by

Maria Costantini

Valerio Zupo

and

Roberta Esposito

submission deadline 25 Dec 2026 | Viewed by 331 | Submission Open

Keywords: biodiversity; biomarkers; biomonitoring; marine organisms; pollution; metals; microplastics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the Design, Synthesis, and Characterization of Metal Complexes with Multifaceted Biological Activities

edited by

Luca Conti

submission deadline 25 Dec 2026 | Viewed by 307 | Submission Open

Keywords: metal complexes; molecular design; biological activity; structure– activity relationships; therapeutic applications

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Research on the Molecular Mechanisms Related to Exercise

edited by

Kayvan Khoramipour

submission deadline 25 Dec 2026 | Viewed by 306 | Submission Open

Keywords: exercise; molecules; disease

(This special issue belongs to the Section Molecular Biology)

Exploring the Functional Activity of Natural Products

edited by

Antonio Speciale

submission deadline 25 Dec 2026 | Viewed by 300 | Submission Open

Keywords: natural products; natural drug discovery; bioactive compounds; biological activity; molecular mechanisms; anti-inflammatory activity; anticancer properties; therapeutic potential

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Regulatory Mechanism and Network of Abiotic Stress-Response in Plants: 3rd Edition

edited by

Yong-Hwan Moon

submission deadline 25 Dec 2026 | Viewed by 272 | Submission Open

Keywords: abiotic stress response; osmotic stress; temperature stress; transcriptional regulation; post-transcriptional regulation; regulatory mechanism; gene regulatory network

(This special issue belongs to the Section Molecular Plant Sciences)

Polymer Composites: Macromolecular Structure and Application

edited by

Donatella Duraccio

submission deadline 25 Dec 2026 | Viewed by 268 | Submission Open

Keywords: polymer composites; macromolecular structure; reinforcement strategies; structure– property relationships; sustainable materials

(This special issue belongs to the Section Macromolecules)

Biocatalysis: Mechanisms of Proteolytic Enzymes, 3rd Edition

edited by

Peter Goettig

submission deadline 25 Dec 2026 | Viewed by 254 | Submission Open

Keywords: aspartic proteases; cryptic ligand binding sites; cysteine proteases; metalloproteases; non-canonical amino acids; prodrugs; protease ligases; SARS-CoV-2 proteases; serine proteases; threonine proteases

(This special issue belongs to the Section Molecular Biophysics)

Molecular Mechanisms and Treatment Strategies in Diabetic Kidney Disease

edited by

Érika Bevilaqua Rangel

submission deadline 25 Dec 2026 | Viewed by 234 | Submission Open

Keywords: diabetic kidney disease; oxidative stress; autophagy; inflammation; fibrosis; cell therapy; SGLT2 inhibitors and GLP-1 agonists; mesenchymal stem cells; gene therapy; translational nephrology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomass as Feedstock for the Production of High Value-Added Chemicals by Heterogeneous Catalysis

edited by

Cristina García-Sancho

submission deadline 25 Dec 2026 | Viewed by 221 | Submission Open

Keywords: biomass; heterogeneous catalysts; biofuels; bioproducts; platform molecules

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Immune Mechanisms of Autoimmune Rheumatic Diseases

edited by Immacolata Pietraforte

submission deadline 25 Dec 2026 | Viewed by 220 | Submission Open

Keywords: autoimmune diseases; autoinflammatory diseases; inflammation and immune-mediated diseases; T and B cells; APCs; Treg. Th17/Th23; chemokines

(This special issue belongs to the Section Molecular Immunology)

Displaying special issue 2951-3000 on page 60 of 65.

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