Advancements in Antioxidant Molecules: From Discovery to Therapeutic Applications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 20 April 2026 | Viewed by 158
Special Issue Editor
Interests: organic chemistry; medicinal chemistry; drug design; organocatalysis; photocatalysis; drug discovery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Reactive oxygen species (ROS) are commonly produced by cells during normal metabolic activity, and, under physiological conditions, different antioxidant enzymes mediate their removal. Without correct inactivation or in case of over-exposure to ROS inducer factors, oxidative stress is closely related to several pathological conditions, from skin photo-aging processes to carcinogenesis.
In this Special Issue, we will collect innovative studies about the development of small molecules endowed with potential antioxidant activities. Innovative aspects, novel biological mechanisms of action, and novel target validation are also welcome. In conclusion, this Special Issue focuses on the study of natural and synthetic antioxidant compounds, their pharmacological evaluation, computational modeling, and structural biology studies.
Dr. Davide Moi
Guest Editor
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Keywords
- antioxidants
- natural products
- small molecules
- polyphenols
- reactive oxygen species
- drug discovery
- oxidative stress
- apoptosis
- target validation
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