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Advancements in Antioxidant Molecules: From Discovery to Therapeutic Applications

This special issue belongs to the section “Molecular Pharmacology“.

Special Issue Information

Dear Colleagues,

Reactive oxygen species (ROS) are commonly produced by cells during normal metabolic activity, and, under physiological conditions, different antioxidant enzymes mediate their removal. Without correct inactivation or in case of over-exposure to ROS inducer factors, oxidative stress is closely related to several pathological conditions, from skin photo-aging processes to carcinogenesis.

In this Special Issue, we will collect innovative studies about the development of small molecules endowed with potential antioxidant activities. Innovative aspects, novel biological mechanisms of action, and novel target validation are also welcome. In conclusion, this Special Issue focuses on the study of natural and synthetic antioxidant compounds, their pharmacological evaluation, computational modeling, and structural biology studies.

Dr. Davide Moi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidants
  • natural products
  • small molecules
  • polyphenols
  • reactive oxygen species
  • drug discovery
  • oxidative stress
  • apoptosis
  • target validation

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Int. J. Mol. Sci. - ISSN 1422-0067