Molecular Biology, Genetics, Diagnosis, Management and Therapy of Dermatological Diseases

Dear Colleagues,

Dermatologic diseases affect millions of individuals globally, and they are complex ones due to polygenic background, immune mechanisms, and environmental triggers. A rising prevalence fosters continuous advancements in molecular research, diagnosis, and treatment options. Investigating novel approaches to inflammatory and oxidative diseases, disease progression, pharmacological prevention, and intervention strategies is paramount. In fact, understanding pathophysiology as well as the development of novel diagnostic tools and targeted therapies is very important in diseases such as skin allergies.Hidradenitis suppurativa is due to genetic, immunological, and microbial factors that contribute to pathogenesis; innovative therapeutic approaches are being used. Contributions that explore novel molecular targets, biomarkers, and treatment strategies of skin diseases are welcome.Coordination between researchers, diagnosis, and possible therapies undoubtedly will advance the work of physicians and benefit patients.For example, ultrasound can be used in order to evaluate genetic or subclinical skin diseases before they are clinically detectable. Ultrasound can also guide treatments and evaluate therapy-related skin changes before they can be clinically assessed. A recent example of that is the treatment assessment of cutaneous exosomes using color Doppler ultrasound.We welcome articles about current challenges and future perspectives in the management of skin conditions, including those covering approaches to wound healing, skin regeneration, atopic dermatitis, psoriasis, and acne, among others. An in-depth assessment of molecular mechanisms that maintain skin homeostasis, the identification of disease-associated biomarkers, the characterization of dysregulated signaling pathways, and the discovery of novel therapeutic targets in inflammatory, autoimmune, infectious, and neoplastic skin diseases are very important fields of study.

Furthermore, new target therapies are emerging along with the discovery of new paths and pathogenic mechanisms.

For this Special Issue, supervised by the Guest Editor group and assisted by Dr. Corrado Tagliati (AST Ancona, Ancona, Italy), the aim of this Special Issue is to gather research articles and reviews about dermatopathology, genetics, diagnostics, management, and therapy of dermatological diseases.

Dr. Elisa Molinelli
Dr. Corrado Tagliati
Guest Editors

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