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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Pharmacology and Interventions in Cardiovascular Disease

edited by

Magdalena Zabielska-Kaczorowska

submission deadline 20 Mar 2025 | 6 articles | Viewed by 7143 | Submission Open

Keywords: cardiovascular pharmacology; cardiovascular interventions; cardioprotection; myocardial ischemia and infarction; heart failure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biopolymers as Nanoparticles Carriers, 2nd Edition

edited by

Magdalena Krystyjan

and

Gohar Khachatryan

submission deadline 20 Mar 2025 | 4 articles | Viewed by 7062 | Submission Open

Keywords: nanomaterials; (nano)fillers; nanoparticles; nanotubes; quantum dots; nanostructures; nanometals; nanocapsules; biopolymers; biocomposites

(This special issue belongs to the Section Materials Science)

Mitochondria-Mediated Oxidative Stress in Diseases: Cell Death and Treatment

edited by

Renata A. Zvyagilskaya

submission deadline 20 Mar 2025 | 5 articles | Viewed by 6904 | Submission Open

Keywords: mitochondrial dysfunction; reactive oxygen species; oxidative stress; mitochondrial biogenesis; mitotherapy; neurodegenerative diseases; cardiovascular diseases; cancer; biomarkers; mitochondrial dynamics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ion Conductance and Ion Regulation in Human Health and Disease

edited by

Lars Kaestner

submission deadline 20 Mar 2025 | 5 articles | Viewed by 6819 | Submission Open

Keywords: ion channels; membrane potential; action potential; ion pumps; uniporter; co-transporter; patch-clamp; ion flux; concentration gradient; ion stores

(This special issue belongs to the Section Molecular Biology)

Drug Discovery of Compounds by Structural Design

edited by

Paulino Gómez-Puertas

submission deadline 20 Mar 2025 | 5 articles | Viewed by 6735 | Submission Open

Keywords: drug discovery; virtual screening; molecular dynamics; computational biology; drug repurposing

(This special issue belongs to the Section Molecular Biophysics)

Recent Developments on Protein–Ligand Interactions: From Structure, Function to Applications 2.0

edited by

Alexandre G. De Brevern

submission deadline 20 Mar 2025 | 3 articles | Viewed by 6261 | Submission Open

Keywords: protein– ligand analysis; protein– ligand interaction fingerprints; structure protein– ligand interaction relationships; structure– activity relationships; molecular modeling; molecular dynamics; chemogenomics; chemical biology; drug discovery and design; fragment-based lead discovery; 2D interaction maps; 3D activity; hotspots; pharmacophore

(This special issue belongs to the Section Biochemistry)

Chronic Inflammation: Pathophysiological Process and Nutritional Interventions

edited by

Sara Bindoli

and

Francesca Oliviero

submission deadline 20 Mar 2025 | 3 articles | Viewed by 6060 | Submission Open

Keywords: chronic disorders; inflammatory diseases; dietary habits; nutraceuticals; bioactive compounds

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Biopolymeric Materials Incorporating Bioactive Ingredients and Their Applications

edited by

Carlos Regalado-González

submission deadline 20 Mar 2025 | 3 articles | Viewed by 6015 | Submission Open

Keywords: biopolymers; encapsulated bioactive agents; antioxidants; antimicrobials; extended release

(This special issue belongs to the Section Materials Science)

Role of MicroRNAs in Human Diseases

edited by

Lorenzo F. Sempere

submission deadline 20 Mar 2025 | 6 articles | Viewed by 5925 | Submission Open

Keywords: microRNAs; miRNAs; miRs; preclinical models; target interaction; regulatory networks; oncology; cancer biology; cardiovascular disease; neurodegenerative conditions; diagnostic applications; therapeutic development and clinical trials

(This special issue belongs to the Section Molecular Genetics and Genomics)

Mesenchymal Stem Cells: Cross-Talk with the Microenvironment

edited by

Natella Enukashvily

and

Anna Malashicheva

submission deadline 20 Mar 2025 | 4 articles | Viewed by 5890 | Submission Open

Keywords: mesenchymal stem cell niche; microenvironment; cell-to-cell interaction; tumor microenvironment; inflammation; stem cells transcriptome; extracellular vesicles

(This special issue belongs to the Section Biochemistry)

Recent Research in Gut Microbiota–Gut–Brain Axis

edited by Ying Han

submission deadline 20 Mar 2025 | 2 articles | Viewed by 5864 | Submission Open

Keywords: microbiota; dysbiosis; microbiota– gut– brain axis; short-chain fatty acid; immune pathway; vagus nerve; neuropsychiatric disorders; depression

(This special issue belongs to the Section Molecular Biology)

Molecular Insight into Leukemia

edited by Claire Lucas and

Ioannis Kanakis

submission deadline 20 Mar 2025 | 3 articles | Viewed by 5826 | Submission Open

Keywords: AML; CML; ALL; CLL; MLL; acute leukemia; chronic leukemia; myeloproliferative disorders; biomarkers; treatment; clinical outcome; treatment-free remission; bone marrow microenvironment

(This special issue belongs to the Section Molecular Oncology)

Renal Cell Carcinoma: Novel Insights into Pathophysiology, Diagnosis and Therapy

edited by

Giuseppe Lucarelli

submission deadline 20 Mar 2025 | 4 articles | Viewed by 5700 | Submission Open

Keywords: renal cell carcinoma; biomarker; diagnosis; robot-assisted surgery; therapy

(This special issue belongs to the Section Molecular Oncology)

Food Nutrition and Lipid Metabolism

edited by

Rui Jiao

submission deadline 20 Mar 2025 | 2 articles | Viewed by 5696 | Submission Open

Keywords: food nutrition; lipid metabolism; cholesterol; triglyceride; functional food; nutraceuticals; dietary patterns; cardiovascular disease; obesity; diabetes; COVID-19; molecular nutrition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Genetic Biology in Embryonic Development

edited by Adam Davis

submission deadline 20 Mar 2025 | 3 articles | Viewed by 5643 | Submission Open

Keywords: embryonic development; evolution and development; genetic regulatory networks; gene expression and regulation; cellular and subcellular morphogenesis; anatomical patterning; genomic– environmental interactions; axis development; medical disorders; molecular genetics

(This special issue belongs to the Section Molecular Biology)

Molecular Approaches to Male Infertility: From Diagnosis to Decision-Making

edited by

Rossella Cannarella

and

Aldo E. Calogero

submission deadline 20 Mar 2025 | 3 articles | Viewed by 5411 | Submission Open

Keywords: male infertility; sperm; omics; epigenome; transcriptome; proteome; metabolome; assisted reproductive technique (ART)

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Epigenetics and Beyond: New Advances in Drug Discovery

edited by

Gabriele Carullo

Valeria Tudino

and

Maria Dichiara

submission deadline 20 Mar 2025 | 3 articles | Viewed by 5392 | Submission Open

Keywords: epigenetic modifications; epigenetic targets; drug design; drug discovery; cancer; infectious disease; immunology; inflammation; neurological diseases; fibrosis; wound repair and regeneration

(This special issue belongs to the Section Molecular Pharmacology)

Nitric Oxide Synthases: Function and Regulation: 2nd Edition

edited by

Tzong-Shyuan Lee

submission deadline 20 Mar 2025 | 5 articles | Viewed by 5390 | Submission Open

Keywords: nitric oxide synthases; isoforms; nitric oxide; endothelial cell; stem cell; cellular signaling; redox pathway; endothelial NOS; neuronal NOS; disease; cancer

(This special issue belongs to the Section Biochemistry)

Antimicrobial and Antiviral Peptides

edited by

Tecla Ciociola

submission deadline 20 Mar 2025 | 5 articles | Viewed by 5276 | Submission Open

Keywords: antimicrobial peptides; antiviral peptides; peptide mining; molecular mechanism of biological activity; structure– activity relationship; molecular targets; in silico design; in vivo models; peptide delivery strategies; biomedical applications

(This special issue belongs to the Section Molecular Pharmacology)

Ovarian Dysfunction, Infertility and Its Treatment

edited by

Stefano Palomba

submission deadline 20 Mar 2025 | 3 articles | Viewed by 5133 | Submission Open

Keywords: ovulatory disorders; menstrual disorders; infertility; new drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cystic Fibrosis: Molecular Pathogenesis, Diagnosis, and Treatment

edited by Valeria Rachela Villella

submission deadline 20 Mar 2025 | 4 articles | Viewed by 4876 | Submission Open

Keywords: CFTR protein interactions; molecular mechanism and processing; modulators; new drugs; pathogenesis and theratyping

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research on Cancer Drug Resistance

edited by

Jean-Pierre Jaffrézou

submission deadline 20 Mar 2025 | 2 articles | Viewed by 4629 | Submission Open

Keywords: chemotherapy; drug resistance; immunotherapy; immunotherapy resistance; signal transduction

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in Apoptosis and Autophagy

edited by

Alessandra Stacchiotti

and

Annalisa Cappella

submission deadline 20 Mar 2025 | 2 articles | Viewed by 4505 | Submission Open

Keywords: efferocytosis; apoptosis; autophagy; mitophagy; cell death mechanisms; aging; cardiovascular diseases; musculoskeletal diseases; nutraceutical and natural modulators

(This special issue belongs to the Section Biochemistry)

Editorial Board Members’ Collection Series: Genome Stability

edited by

Tae-Hong Kang

and

Lasse Lindahl

submission deadline 20 Mar 2025 | 3 articles | Viewed by 4122 | Submission Open

Keywords: genome stability; DNA damage response; DNA repair; DNA replication; DNA recombination; ATR/ATM pathway; GENOTOXINS

(This special issue belongs to the Section Molecular Genetics and Genomics)

Design of Functional Supramolecular Architectures Based on Coordination Compounds

edited by

Sergey V. Baykov

and

Nadezhda A. Bokach

submission deadline 20 Mar 2025 | 3 articles | Viewed by 3988 | Submission Open

Keywords: supramolecular architectures; noncovalent interactions; metal complexes; functional material; structure– properties relationship; DFT calculations; metal– organic framework; coordination polymer; semi-coordination; staking

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Computational Research in Pharmacological and Toxicological Issues

edited by

Yoshihiro Uesawa

submission deadline 20 Mar 2025 | 2 articles | Viewed by 3784 | Submission Open

Keywords: in silico study; computational toxicology; adverse drug reaction; drug discovery; QSAR analysis; machine learning; artificial intelligence

(This special issue belongs to the Section Molecular Informatics)

Polyphenols Hazard and Safety Assessment in Human Health and Food Systems

edited by

Lidia Magerusan

and

Dana Alina Magdas

submission deadline 20 Mar 2025 | 2 articles | Viewed by 3773 | Submission Open

Keywords: polyphenols; food safety; health risk evaluation; graphenes-based sensors; electrochemical detection; chemometrics; artificial intelligence; metabolomics

(This special issue belongs to the Section Biochemistry)

Functional and Structural Genomics Studies for Plant Breeding

edited by

Andrea Cavallini

, Tommaso Giordani and Alberto Vangelisti

submission deadline 20 Mar 2025 | 4 articles | Viewed by 3733 | Submission Open

Keywords: plant transcriptomics; genome sequencing; plant gene function; molecular plant breeding; structural genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Applications of Biomaterials in Drug Development

edited by

Sung Giu Jin

submission deadline 20 Mar 2025 | 2 articles | Viewed by 3713 | Submission Open

Keywords: drug delivery systems; nanomaterials; pharmaceutical engineering; targeting; solubilization technology; controlled release; microneedle; biopolymers

(This special issue belongs to the Section Materials Science)

DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies 3.0

edited by

Marco E. M. Peluso

submission deadline 20 Mar 2025 | 1 articles | Viewed by 3460 | Submission Open

Keywords: DNA Damage; Oxidative Stress; By-Products

(This special issue belongs to the Section Molecular Toxicology)

Molecular Studies on Plant and Plant In Vitro Systems Secondary Metabolism

edited by

Andrey Marchev

submission deadline 20 Mar 2025 | 2 articles | Viewed by 3236 | Submission Open

Keywords: plants; plant in vitro systems; secondary metabolism; sustainable production; elicitation; metabolic engineering; CRISPR/Cas; molecular targets

(This special issue belongs to the Section Molecular Plant Sciences)

Proteasomes and Cellular Senescence: An Age-Related Connection

edited by

Aniruddha Das

submission deadline 20 Mar 2025 | 2 articles | Viewed by 3130 | Submission Open

Keywords: proteasomes; aging; proteasome receptors; post-translational modification

(This special issue belongs to the Section Molecular Biology)

New Advances in Epigenetics and Epigenomics

edited by Vicki Maltby

submission deadline 20 Mar 2025 | 3 articles | Viewed by 2981 | Submission Open

Keywords: epigenetics; epigenomics; multi-omics; epitranscriptomics; single cell

(This special issue belongs to the Section Molecular Genetics and Genomics)

Novel Natural Compound for Wound and Tissue Repair and Regeneration: 3rd Edition

edited by

Elia Ranzato

and

Simona Martinotti

submission deadline 20 Mar 2025 | 3 articles | Viewed by 2962 | Submission Open

Keywords: wound repair; tissue regeneration; natural compounds; phytochemicals; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nanomaterials and Biomaterials in Biomedicine Application

edited by

Filipa Mascarenhas-Melo

submission deadline 20 Mar 2025 | 3 articles | Viewed by 2884 | Submission Open

Keywords: nanomaterials; biomaterials; biomedicine; drug delivery; regenerative medicine; healthcare technologies; biocompatible platforms

(This special issue belongs to the Section Materials Science)

Natural Products as Multitarget Agents in Human Diseases

edited by

Andrey Marchev

and

Nikolina Mihaylova

submission deadline 20 Mar 2025 | 2 articles | Viewed by 2877 | Submission Open

Keywords: natural products; bioactive compounds; human health; disease prevention and treatment; molecular and physiological mechanism; inflammatory diseases; cancer; arthritic diseases

(This special issue belongs to the Section Molecular Pharmacology)

Liposomes as Membrane Models in Drug-Lipid Interactions

edited by

Carla Matos

submission deadline 20 Mar 2025 | 1 articles | Viewed by 2796 | Submission Open

Keywords: liposomes; membrane interactions; drug development

(This special issue belongs to the Section Molecular Pharmacology)

Nanotechnology in Targeted Drug Delivery 2.0

edited by

Antonio Di Stefano

and

Marilisa Pia Dimmito

submission deadline 20 Mar 2025 | 2 articles | Viewed by 2691 | Submission Open

Keywords: pharmaceutical materials; functionalization; nanoformulations; drug release

(This special issue belongs to the Section Molecular Nanoscience)

Heartfulness: Contributors of Healthy and Unhealthy Cardiac Aging

edited by

Susana P. Pereira

and Laura A. Cox

submission deadline 20 Mar 2025 | 1 articles | Viewed by 2614 | Submission Open

Keywords: cardiac development; gene regulation; epigenetics; genomics; integrated omics; accelerated aging; cardiac metabolism; cardiac regeneration and repair; cardiovascular diseases; cutting-edge techniques; cardiac imaging; regenerative mechanisms; pathophysiology of cardiovascular disease; cardiac endothelium; cardiomyocytes; cardiovascular computational modeling; cardiovascular informatics; transgenerational inheritance; life expectancy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Fatty Acid Oxidation, Lipid Mediators and Dietary Fatty Acids in the Molecular Mechanisms of Diseases

edited by

Cinzia Signorini

submission deadline 20 Mar 2025 | 3 articles | Viewed by 2611 | Submission Open

Keywords: fatty acid oxidation; inflammation; lipid mediators; lipid metabolism; omega-3 fatty acids; oxidative stress; dietary supplementation; animal models; human diseases

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Application of Fluorescence Imaging and Super-Resolution Imaging in Molecular Biology

edited by

Keigo Kohara

submission deadline 20 Mar 2025 | 2 articles | Viewed by 2590 | Submission Open

Keywords: fluorescence imaging; super-resolution imaging; molecular biology; disease; biomolecules; organelles; morphologies of cells; iPS cells; organoids; molecular biology

(This special issue belongs to the Section Molecular Biophysics)

Plant Development and Hormonal Signaling

edited by

Naoufal Lakhssassi

submission deadline 20 Mar 2025 | 3 articles | Viewed by 2525 | Submission Open

Keywords: plant growth; reproductive growth; phytohormones; signal transduction; transcription factors; root development; shoot development; floral development; seed development; environmental interactions; regulatory networks; apical dominance

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Neuromuscular Transmission in Health and Disease

edited by

Michele Salanova

submission deadline 20 Mar 2025 | 1 articles | Viewed by 2522 | Submission Open

Keywords: neuromuscular junction; muscle atrophy; muscle postsynaptic signaling; muscle myopathy; NMJ in vitro models

(This special issue belongs to the Section Molecular Neurobiology)

The Role of Glia in Neuropsychiatric Disorders

edited by

Guillaume Lucas

submission deadline 20 Mar 2025 | 2 articles | Viewed by 2454 | Submission Open

Keywords: glial cells; astrocytes; microglia; neuro-inflammation; synaptic plasticity; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Neurobiology)

Mucopolysaccharidoses: Diagnosis, Treatment and Management 4.0

edited by

Shunji Tomatsu

Grzegorz Wegrzyn

and Roberto Giugliani

submission deadline 20 Mar 2025 | 1 articles | Viewed by 2416 | Submission Open

Keywords: mucopolysaccharidoses; glycosaminoglycans; proteoglycans; lysosomal dysfunction; cell function; metabolic disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Abnormal Organelles and Protein Expression in Acute and Chronic Neurodegeneration

edited by

Francesco Fornai

submission deadline 20 Mar 2025 | 2 articles | Viewed by 2412 | Submission Open

Keywords: brain ischemia; epileptic damage; basal ganglia pathology; catecholamine cell damage; excitotoxicity; autophagy; dopamine system norepinephrine system; protein unfolding; protein misfolding; cholinergic system

(This special issue belongs to the Section Molecular Neurobiology)

DNA Damage in Neurological Disorders: Etiological and Therapeutical Aspects

edited by Tam Quach, Ilaria Palmisano and Anne-Marie Duchemin

submission deadline 20 Mar 2025 | 1 articles | Viewed by 2401 | Submission Open

Keywords: neurological disorders; peripheral neuropathies; DNA damage; epigenetic dynamism; 3D chromatin organization/remodeling; therapeutic targets for DNA repair

(This special issue belongs to the Section Molecular Neurobiology)

Gastrointestinal Cancer: From Pathophysiology to Novel Therapeutic Approaches

edited by

Marlena Brzozowa-Zasada

submission deadline 20 Mar 2025 | 2 articles | Viewed by 2379 | Submission Open

Keywords: gastrointestinal cancer; molecular pathology; innovative therapies; targeted therapy; immunotherapy; cancer resistance

(This special issue belongs to the Section Molecular Oncology)

Molecular Research and Treatment in Multiple Sclerosis

edited by Nada Starčević Čizmarević and

Borut Peterlin

submission deadline 20 Mar 2025 | 2 articles | Viewed by 2285 | Submission Open

Keywords: multiple sclerosis; neuroinflammation; neurodegeneration; genetics; molecular research; biomarkers; neuroimaging; therapy

(This special issue belongs to the Section Molecular Biology)

Innovative Molecular Strategies in Biomedicine

edited by

Rui Vitorino

submission deadline 20 Mar 2025 | 2 articles | Viewed by 2238 | Submission Open

Keywords: bioprinting; organ-on-chip; venom-derived therapeutics; 3D in vitro models; skeletal muscle models; toxic peptides; peptide expression; nanoparticles in medicine; protein and peptide drug delivery; peptide-based biomaterials; self-assembled hydrogels; molecular therapeutics; nanotechnology in drug delivery; regenerative medicine; tissue engineering

(This special issue belongs to the Section Materials Science)

Displaying special issue 2901-2950 on page 59 of 65.

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