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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pain: From Molecular Basis to Therapy

edited by Samuel J. Lin

submission deadline 28 Feb 2025 | Viewed by 52 | Submission Open

Keywords: pain mechanisms; molecular signaling; neurotransmitters; ion channels; genetic predisposition; epigenetic regulation; immune– neuron interaction; pharmacological therapy; gene therapy; neuromodulation; regenerative medicine

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Combinatorial Therapies for Spinal Cord Injury

edited by

Lingxiao Deng

submission deadline 28 Feb 2025 | Viewed by 51 | Submission Open

Keywords: molecular; cellular; engineering; spinal cord injury

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Human Induced Pluripotent Stem Cells in Disease Modeling and Cell-Based Therapies—Challenges and Perspectives

edited by Urszula Florczyk-Soluch and

Agnieszka Łoboda

submission deadline 28 Feb 2025 | Viewed by 51 | Submission Open

Keywords: induced pluripotent stem cells; disease modeling; stem cell differentiation; three-dimensional cell culture; 3D organoids

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Molecular Basis of Vascular Pathology

edited by

Jolanta Neubauer-Geryk

submission deadline 28 Feb 2025 | Viewed by 51 | Submission Open

Keywords: vascular pathologies; blood vessels; dysfunction; vascular damage; blood flow; biomarkers; biomolecules; cytokines

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antioxidants as Regulators of Metabolic Pathways: Potential and Therapeutic Strategies

edited by Halina Tkaczenko

submission deadline 28 Feb 2025 | Viewed by 50 | Submission Open

Keywords: antioxidants; metabolic pathways; oxidative stress; cellular homeostasis; redox signaling; energy metabolism; lipid metabolism; therapeutic strategies; chronic diseases

(This special issue belongs to the Section Molecular Biology)

Advances in Rare Diseases Biomarkers: 2nd Edition

edited by

Andrea Bernini

submission deadline 28 Feb 2025 | Viewed by 49 | Submission Open

Keywords: orphan diseases; rare diseases; inborn errors of metabolism; mitochondrial disorders; biomarker discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of the Endocannabinoid System in Reward- and Addiction-Related Neuroplasticity

edited by

Francisco Navarrete-Rueda

and

María S. García Gutiérrez

submission deadline 28 Feb 2025 | Viewed by 48 | Submission Open

Keywords: endocannabinoid system; neuroplasticity; reward; addiction; biomarker; therapeutic approach

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances and Challenges in Colorectal Cancer: From Molecular Research to Treatment

edited by

Premila Leiphrakpam

submission deadline 28 Feb 2025 | Viewed by 48 | Submission Open

Keywords: tumor biology; tumor heterogeneity; molecular mechanism involved in cancer initiation; progression; and metastasis; compensatory pathways; cancer screening; cancer biomarkers discovery; tumor molecular profiling methods; early cancer diagnosis; novel therapeutic strategies; targeted therapies; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms and Novel Therapies for Colon Cancer

edited by

Bin Guo

submission deadline 28 Feb 2025 | Viewed by 47 | Submission Open

Keywords: colon cancer; molecular mechanism; targeted therapies; genetics and epigenetics; anticancer drug

(This special issue belongs to the Section Molecular Oncology)

Recent Research of Protein Structure Prediction and Design

edited by

Alexandre G. De Brevern

submission deadline 28 Feb 2025 | Viewed by 46 | Submission Open

Keywords: protein design; multidomain proteins; AlphaFold2; protein folding; deep learning

(This special issue belongs to the Section Biochemistry)

Diet Effects on Neurocognitive Functioning

edited by Jonathan Fusi

submission deadline 28 Feb 2025 | Viewed by 46 | Submission Open

Keywords: nutrition; cognition; brain disease; brain; oxidative stress; antioxidant; sports exercise; exercise

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Biology and Diagnosis on Biliary and Pancreatic Cancers

edited by Francesco Vasuri and Luca Saragoni

submission deadline 28 Feb 2025 | Viewed by 43 | Submission Open

Keywords: biliary cancer; pancreatic cancer; histological diagnoses; cytological diagnoses; chromosome aneuploidy; specific genetic mutations

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights into Role of Anthranilic Acid in Neuropsychiatric Diseases

edited by Gregory F. Oxenkrug

submission deadline 28 Feb 2025 | Viewed by 43 | Submission Open

Keywords: anthranilic acid; Alzheimer’ s disease; autism; schizophrenia; bipolar disorder; major depressive disorder; post-partum depression; COVID-19; interferons; attention deficit disorder; cognitive impairment; G-protein-coupled receptor 109A; microbiome; gut– brain axis

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Microbial Dynamics in Agroforestry for Resilience and Climate Adaptation

edited by

Amrita Chakraborty

and

Amit Roy

submission deadline 28 Feb 2025 | Viewed by 43 | Submission Open

Keywords: agroforestry; soil microbes; plant-microbe interactions; microbial influence; microbiomes; insect-microbe interactions; horizontal gene transfer

(This special issue belongs to the Section Molecular Plant Sciences)

Roles of Lipid Rafts in Metabolisms

edited by

Kohji Kasahara

submission deadline 28 Feb 2025 | Viewed by 42 | Submission Open

Keywords: lipid rafts; glycosphingolipid; ganglioside; sphingomyelin; cholesterol; GPI-anchored proteins; caveolae; detergent-resistant membrane; signal transduction; disease

(This special issue belongs to the Section Biochemistry)

Experimental Models and Applications in Muscle Regeneration

edited by

Daiva Bironaite

submission deadline 28 Feb 2025 | Viewed by 42 | Submission Open

Keywords: stem cells; internal and external stimuli; scaffolds; signaling systems; muscle regeneration mechanisms

(This special issue belongs to the Section Molecular Biology)

New Advances in the Field of Thrombosis and Hemostasis

edited by

Claudia Maria Radu

submission deadline 28 Feb 2025 | Viewed by 42 | Submission Open

Keywords: bleeding; thrombosis; new diagnostic tests; rare diseases; platelet function; biomarkers; risk factors; thrombocytopenia; endothelial dysfunction; autoantibodies; extracellular vesicles; stem cells; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Molecular Research on the Diagnosis and Treatment of Chronic Liver Diseases

edited by

Hirayuki Enomoto

submission deadline 28 Feb 2025 | Viewed by 40 | Submission Open

Keywords: biomarker; genomic research; epigenomic research; molecular mechanisms; viral hepatitis; alcoholic-related liver disease; non-alcoholic fatty liver disease; autoimmune liver diseases; liver cirrhosis; hepatocellular carcinoma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research and Recent Advances of Antimicrobials

edited by

Már Másson

submission deadline 28 Feb 2025 | Viewed by 40 | Submission Open

Keywords: antibiotic; antibacterial; antifungal; antiviral; chemical synthesis; drug discovery; natural products; small molecules; peptides; proteins; oligosaccharides; polysaccharides; drug delivery; nanoparticles; solutions; gels; formulation; nanoparticles; materials; coat-ings; drug release; structure– activity; mechanism of action; clinical application; veterinary applications; agricultural applications; food preservation

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into Kidney Disease: Physiopathology, Molecular Diagnostics, and Therapy

edited by

Chien-Te Lee

submission deadline 28 Feb 2025 | Viewed by 40 | Submission Open

Keywords: kidney; physiology; pathology; pathogenesis; molecular mechanism; diagnosis; therapy; dialysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Toxicity Research of Biological Venoms

edited by

Karla De Castro Figueiredo Bordon

and Suely Vilela Sampaio

submission deadline 28 Feb 2025 | Viewed by 39 | Submission Open

Keywords: neurotoxicity assays; insect models; electrophysiology; screening assays; ion channels; therapeutic molecules; animal venoms; antitumoral activity; enzyme activity; biotechnological application

(This special issue belongs to the Section Molecular Toxicology)

Molecular Genetics and Plant Breeding, 5th Edition

edited by

Hai Du

submission deadline 28 Feb 2025 | Viewed by 38 | Submission Open

Keywords: crop biodiversity; wild accessions; molecular breeding; QTL and gene mapping; comparative genomics; drought stress adaptation; disease resistance; yield and sustainability; GWAS mapping; predictive breeding; genomic prediction

(This special issue belongs to the Section Molecular Genetics and Genomics)

Integrating Molecular Insights on Plant Microbes and Insect Pests

edited by

Xifeng Wang

submission deadline 28 Feb 2025 | Viewed by 38 | Submission Open

Keywords: pathogenic microbes; resistance mechanisms; signaling pathways; omics technologies; plant and insect interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Nucleic Acid Aptamers in Molecular Medicine

edited by

Silvia Catuogno

submission deadline 28 Feb 2025 | Viewed by 38 | Submission Open

Keywords: aptamers; SELEX; targeted therapy; drug delivery; diagnosis; biomarker discovery

(This special issue belongs to the Section Molecular Biology)

Materials for Photobiology—3rd Edition

edited by

Enrico Caruso

Antonino Mazzaglia

and

Angela Scala

submission deadline 28 Feb 2025 | Viewed by 38 | Submission Open

Keywords: light-responsive materials; phototherapeutics; photodiagnosis; bioimaging; living bioluminescent materials; light-induced therapy; UV-radiation effect; photo-antinfective materials; photosensory biology; molecular optogenetics

(This special issue belongs to the Section Materials Science)

Advances in Plant Development and Hormonal Responses

edited by

Soulaiman Sakr

submission deadline 28 Feb 2025 | Viewed by 38 | Submission Open

Keywords: plant development; gene editing; gene editing; plant hormone; biosynthesis

(This special issue belongs to the Section Molecular Plant Sciences)

Ferroptosis Mechanisms and Bone Diseases

edited by

Chundo Oh

submission deadline 28 Feb 2025 | Viewed by 37 | Submission Open

Keywords: ferroptosis; cell death; iron accumulation; lipid peroxidation; bone-related diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Tumor Microenvironment and Cancer Progression: Molecular Insights for Targeted Therapy

edited by

Tetiana Zaǐchuk

submission deadline 28 Feb 2025 | Viewed by 36 | Submission Open

Keywords: tumor microenvironment; immune response modulation; signaling pathways; extracellular matrix components; tumor evolution

(This special issue belongs to the Section Molecular Oncology)

Hormones, Cancer and Complexity: From Molecules to Mechanisms

edited by

Yuet-Kin Leung

and

Shuk-Mei Ho

submission deadline 28 Feb 2025 | Viewed by 35 | Submission Open

Keywords: hormones; cancer; epigenetics; metabolites

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Biomaterials and Therapeutics for Pulp-Dentin Complex Regeneration

edited by

Paulo J. Palma

and

Marco C. Bottino

submission deadline 28 Feb 2025 | Viewed by 35 | Submission Open

Keywords: biomaterials; dental materials; regenerative dentistry; pulp regeneration scaffolds; tissue engineering

(This special issue belongs to the Section Materials Science)

Advanced Research in Retina: 3rd Edition

edited by

Juan J. Salazar

and

José A. Fernández-Albarral

submission deadline 28 Feb 2025 | Viewed by 35 | Submission Open

Keywords: glaucoma; age-related macular degeneration; diabetic retinopathy; neurodegenerative diseases; diagnostic techniques; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Unraveling the Molecular Mechanisms of Neurodegeneration

edited by

Michela Ferrucci

submission deadline 28 Feb 2025 | Viewed by 34 | Submission Open

Keywords: protein accumulation; mitochondria; genetic and epigenetic alterations; oxidative stress; apoptosis; autophagy

(This special issue belongs to the Section Molecular Neurobiology)

Insights into Neurological and Psychiatric Diseases from Drosophila Models

edited by

Efthimios M. C. Skoulakis

submission deadline 28 Feb 2025 | Viewed by 34 | Submission Open

Keywords: disease model development; disease model validation; GWAS validation; ameliorative approaches; pharmacogenetics; pharmacoproteomics; disease mechanisms; suppressor/enhancer genetic screens; synthetic lethality screens; biomarker screens and validation

(This special issue belongs to the Section Molecular Neurobiology)

Host-Pathogen Interactions during Persistent Bacterial Infections, 2nd Edition

edited by

Bettina Löffler

submission deadline 28 Feb 2025 | Viewed by 34 | Submission Open

Keywords: bacteria; intracellular adaptation; metabolic adaptation; metabolic host reprogramming; host– pathogen interaction; chronic infections; regulation of virulence

(This special issue belongs to the Section Molecular Microbiology)

Advances in Molecular Understanding of Ocular Adnexal Disease, 2nd Edition

edited by Robert M. Verdijk

submission deadline 28 Feb 2025 | Viewed by 33 | Submission Open

Keywords: ocular adnexa; neoplasm; carcinoma; melanoma; lymphoma; degeneration; inflammation; immune disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Lipid Metabolism in Human Health and Diseases

edited by

Arianna Vignini

submission deadline 28 Feb 2025 | Viewed by 33 | Submission Open

Keywords: lipids; fatty acids; lipid metabolism; metabolic disorders; cardiovascular diseases; neurodegenerative diseases; cancers

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Immunotherapy in Cancer

edited by

Nethaji Muniraj

submission deadline 28 Feb 2025 | Viewed by 33 | Submission Open

Keywords: immunotherapy; biomarkers; immune modulation; combination therapies; solid tumors; hematological malignancies

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Human Genetics (2nd Edition)

edited by

Fatimah L. C. Jackson

submission deadline 28 Feb 2025 | Viewed by 33 | Submission Open

Keywords: human genomics; mutation; sequencing; variants; human microevolution; epigenomic; human diversity

(This special issue belongs to the Section Molecular Genetics and Genomics)

Cancer Immunotherapy Biomarkers

edited by Ilias P. Nikas,

Ioannis Pateras

and

Apostolos Zaravinos

submission deadline 28 Feb 2025 | Viewed by 33 | Submission Open

Keywords: tumor microenvironment; tumor immunology; cancer biomarkers; immunotherapy; immunohistochemistry; pathology; personalized medicine; omics technologies; prognosis and therapy; bioinformatics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nose-to-Brain Drug Delivery: Opportunities and Challenges

edited by

Daisuke Inoue

submission deadline 28 Feb 2025 | Viewed by 32 | Submission Open

Keywords: nose-to-brain drug delivery; brain drug delivery system; CNS diseases; intranasal administration; nasal formulation

(This special issue belongs to the Section Molecular Pharmacology)

Mechanism(s) of HFpEF and HFrEF

edited by

Suresh C. Tyagi

submission deadline 28 Feb 2025 | Viewed by 31 | Submission Open

Keywords: HFpEF; HFrEF; diabetes; hypertension; obesity; microbiota; epigenetics; probiotics; postbiotics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into Hyaluronan in Human Medicine

edited by

Monica Salamone

submission deadline 28 Feb 2025 | Viewed by 31 | Submission Open

Keywords: hyaluronan; regenerative medicine; inflammation; cancer therapy; metabolomics ; hyaluronidases; cell– matrix interaction; glucose metabolism; pathological processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Epigenomic Insights into Diabetes and Related Complications

edited by

Makrina Karaglani

submission deadline 28 Feb 2025 | Viewed by 31 | Submission Open

Keywords: epigenetics; methylation; miRNAs; histone modifications; diabetes; metabolic disease; diabetic complications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advanced Research on Female Reproductive Physiology

edited by Tomoko Fujiwara and

Masanori Ono

submission deadline 28 Feb 2025 | Viewed by 31 | Submission Open

Keywords: circadian rhythm; diet; hypothalamus; lifestyle habits; ovary; pituitary; preconception care; reproduction function; reproductive behavior; uterus

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Inflammation and Metabolic Response in Mitochondrial Diseases

edited by

Guido Primiano

submission deadline 28 Feb 2025 | Viewed by 30 | Submission Open

Keywords: mitochondrial diseases; mitochondria; mtDNA; metabolic remodeling; inflammation; immunity; cell death; neurodegenration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Aspects of Environmental Pollutants on Soil Microbial

edited by Elżbieta Wołejko, Urszula Wydro and Agata Jabłońska-Trypuć

submission deadline 28 Feb 2025 | Viewed by 30 | Submission Open

Keywords: biomonitoring; soil contamination; molecular biology techniques; microbiological activity in soil; toxicological tests; bioindication; ecotoxicology; omics

(This special issue belongs to the Section Molecular Toxicology)

The Immunometabolic Cross-Talk in Complications of Metabolic Syndrome and Diabetes

edited by

Yan Huang

submission deadline 28 Feb 2025 | Viewed by 30 | Submission Open

Keywords: metabolism; immunology; diabetes; metabolic syndrome; obesity; complications; inflammatory response; immune cells; lipids; glucose; sphingolipids

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Crustacean Aquaculture

edited by Tom Levy and

Tomer Ventura

submission deadline 28 Feb 2025 | Viewed by 29 | Submission Open

Keywords: androgenic gland; aquaculture; crustaceans; disease management; gene silencing; genetic modification; monosex; selective breeding; sex reversal; yield improvement

(This special issue belongs to the Section Molecular Biology)

Type 1 Diabetes: Molecular Mechanisms and Therapeutic Approach

edited by Preeti Chhabra

submission deadline 28 Feb 2025 | Viewed by 29 | Submission Open

Keywords: type 1 diabetes; microbiome; proteomics; immunotherapy; β -cell replacement; single-cell sequencing; stem cells; gene editing technologies; tolerance

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Advances in Research of Neuroendocrine Tumors

edited by Tania Amin

submission deadline 28 Feb 2025 | Viewed by 28 | Submission Open

Keywords: neuroendocrine tumors; drug resistance; personalized treatment; molecular subtypes

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 3051-3100 on page 62 of 67.

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