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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cutting Edge Advances in Prostate Cancer submission deadline 20 Sep 2024 | 3 articles | Viewed by 4286 | Submission Open
Keywords: prostate cancer; prognostic and diagnostic biomarkers; therapy resistance; tumor microenvironment; molecular biology
(This special issue belongs to the Section Molecular Oncology)
Molecular Advances in Oncologic Photodynamic Therapy
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 4135 | Submission Open
Keywords: oncology; photodynamic therapy; photosensitizer; targeted drug delivery system; photonanomedicines; phototoxicity; photo cytotoxicity; dark toxicity; superficial tumors; intracellular delivery and localization; anti-tumor immunity; bioinformatics analysis; therapy-induced tumor cell death; stemness of cancer cells
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Targeting of Functional Proteins in Disease Therapeutics: Enzyme Function and Inhibition Studies submission deadline 20 Sep 2024 | 4 articles | Viewed by 4123 | Submission Open
Keywords: enzymes; disease therapeutics; inhibitior
(This special issue belongs to the Section Biochemistry)
Molecular Advance in Abiotic Stress Signaling in Plants: Focus on Atmospheric Stressors submission deadline 20 Sep 2024 | 5 articles | Viewed by 4116 | Submission Open
Keywords: abiotic stress; interactomics; gene expression regulation; kinases; oxidative stress; phytohormones; signaling; sugar sensing and signaling; transcription factors
(This special issue belongs to the Section Molecular Plant Sciences)
Anticancer Activity of Natural Products and Related Compounds submission deadline 20 Sep 2024 | 3 articles | Viewed by 4109 | Submission Open
Keywords: anticancer agent; natural product chemistry; isolation and structure elucidation; medicinal chemistry; molecular mechanism; targeted therapy; structure– activity relationships; phytochemistry; chemical biology
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Update on Immunotherapies for Cancer submission deadline 20 Sep 2024 | 2 articles | Viewed by 4098 | Submission Open
Keywords: cell therapies; monoclonal antibodies; molecular adjuvants; oncolytic therapies; immunogenic; chemotherapy and radiotherapy; cancer vaccines; immunodominance; neoantigens; clinical trials; tumor immune microenvironment
(This special issue belongs to the Section Molecular Oncology)
Design, Synthesis, and Modification of Efficient Catalyst Materials submission deadline 20 Sep 2024 | 5 articles | Viewed by 3998 | Submission Open
Keywords: surface modification; heterogeneous and homogenous catalysis; surface/texture chemistry; physicochemical characterization of catalytic materials; the applications of catalysts; for example; in environmental processes
(This special issue belongs to the Section Materials Science)
New Molecular Insights into Ischemia/Reperfusion
edited by
submission deadline 20 Sep 2024 | 4 articles | Viewed by 3988 | Submission Open
Keywords: vital organs; ischemic injury; cell and organ dysfunction; oxidative stress; inflammation; excitotoxicity
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Function of Glial Cells in the Nervous System
edited by Krista Minéia Wartchow
submission deadline 20 Sep 2024 | 4 articles | Viewed by 3888 | Submission Open
Keywords: glial cells; glial– neuronal interaction; glial biomarkers; neurodegenerative diseases; therapeutic approaches
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Approaches to Male Infertility: From Diagnosis to Decision-Making submission deadline 20 Sep 2024 | 3 articles | Viewed by 3847 | Submission Open
Keywords: male infertility; sperm; omics; epigenome; transcriptome; proteome; metabolome; assisted reproductive technique (ART)
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Immunomodulatory Molecules in Cancer
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3812 | Submission Open
Keywords: cancer; immunomodulatory molecules; mechanism of action; immune system; small-molecule probes; activation/inhibition; biological activity
(This special issue belongs to the Section Molecular Immunology)
Metabolic Regulation in the Development of Cardiovascular Disease and Heart Failure 2.0
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 3756 | Submission Open
Keywords: diabetes; metabolism; dyslipidemia; cardiovascular disease; heart failure; diagnosis; prognosis; therapy
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
New Challenges and Perspectives in Polycystic Ovary Syndrome
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3704 | Submission Open
Keywords: polycystic ovary syndrome; evolutionary origins; developmental origins; pathogenesis; pathophysiology; microbiome; pregnancy complications; lifestyle
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cellular and Molecular Regulatory Signals in Root Growth and Development
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 3611 | Submission Open
Keywords: reactive oxygen species; water supply and deficit; root apoplastic barriers; root architecture; nutrients uptake
(This special issue belongs to the Section Molecular Plant Sciences)
Bioactive Natural Compounds: Protecting Plants and Promoting Human Health submission deadline 20 Sep 2024 | 4 articles | Viewed by 3611 | Submission Open
Keywords: natural products; molecular biology; chemical characterization; bioactivity; mechanism of action; plant protection; human health promotion; antioxidant; anti-inflammation; biopesticides; biostimulants; nutraceuticals
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advances in Molecular Biology and Treatment of Thymic Epithelial Tumors
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3608 | Submission Open
Keywords: thymic epithelial tumors; thymomas; tumor biology; pathogenesis; carcinogenesis; biomarkers; tumor microenvironment; targeted therapy; predictive markers
(This special issue belongs to the Section Molecular Oncology)
Recent Research on Antimicrobial Agents
edited by and
submission deadline 20 Sep 2024 | 4 articles | Viewed by 3578 | Submission Open
Keywords: antimicrobial; antibiotic; multidrug resistant microorganisms; natural products; byproducts; biofilms
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms of Neurological and Psychiatric Disease: A Decade of Progress submission deadline 20 Sep 2024 | 4 articles | Viewed by 3571 | Submission Open
Keywords: Alzheimer's and Parkinson's diseases; epilepsy; migraine; essential tremors; stroke; depression; anxiety disorders; cognitive impairment
(This special issue belongs to the Section Molecular Neurobiology)
Computational Modelling and Molecular Dynamics Simulations of Biological Systems
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3560 | Submission Open
Keywords: molecular dynamics simulations; coarse-graining approaches; computational biophysics; agent-based modeling; mechanistic modeling; multiscale modeling; machine learning; protein structure and function
(This special issue belongs to the Section Molecular Informatics)
Recent Advances in Herpesviruses
edited by
submission deadline 20 Sep 2024 | 4 articles | Viewed by 3379 | Submission Open
(This special issue belongs to the Section Molecular Microbiology)
Novel Pharmacology of Diabetic Complications
edited by and Richard Hulse
submission deadline 20 Sep 2024 | 1 articles | Viewed by 3320 | Submission Open
Keywords: diabetes mellitus; complication; pathophysiology; mechanism; therapeutic strategies
(This special issue belongs to the Section Molecular Pharmacology)
Genetic and Molecular Mechanisms of Resistance or Adaptation to Abiotic Stress in Plants
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 3289 | Submission Open
(This special issue belongs to the Section Molecular Plant Sciences)
Techniques and Strategies in Drug Design and Discovery, 2nd Edition submission deadline 20 Sep 2024 | 4 articles | Viewed by 3201 | Submission Open
Keywords: drug discovery; drug development; target identification; computational drug design; structure-based drug design; ligand-based drug design
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Aspects of Adrenal Diseases and Carcinoma
edited by Tamás Micsík
submission deadline 20 Sep 2024 | 4 articles | Viewed by 3065 | Submission Open
Keywords: adrenal neoplasia; adrenocortical cancer; molecular and genetics; omics; artificial intelligence digital pathology; individualized therapy; prognostication
(This special issue belongs to the Section Molecular Oncology)
Mesenchymal Stem Cells and Their Therapeutic Application 2.0
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 2962 | Submission Open
Keywords: mesenchymal stem cells; regenerating tissue; anti-cancer therapies; therapeutic applications
(This special issue belongs to the Section Molecular Biology)
Advances in Research on Neurogenesis 3.0 submission deadline 20 Sep 2024 | 3 articles | Viewed by 2818 | Submission Open
Keywords: adult neurogenesis; neurodegeneration; aging; psychiatric disorders; cognition; regeneration; adult neurogenesis evolution
(This special issue belongs to the Section Molecular Neurobiology)
New Research on Complexes of Nanoparticles and Bioreceptors: Obtaining, Characterization and Applications
edited by and Yi Wan
submission deadline 20 Sep 2024 | 1 articles | Viewed by 2799 | Submission Open
Keywords: nanoparticles; nanozymes; fluorescent nanoparticles; aggregates of nanoparticles; antibody; aptamer; nanoparticle– bioreceptor conjugates; protein corona; nanoparticle-based biosensors; enhanced immunoassays; isothermal amplification; nanoparticle-based therapy; nanoparticle-based delivery; nanotheranostics
(This special issue belongs to the Section Molecular Nanoscience)
Current Advances in Novel Antiviral Drugs
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 2789 | Submission Open
Keywords: broad-spectrum antivirals; antiviral mechanisms; non-nucleoside antivirals; antiviral resistance; emerging viruses
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Computational Research in Pharmacological and Toxicological Issues
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 2788 | Submission Open
Keywords: in silico study; computational toxicology; adverse drug reaction; drug discovery; QSAR analysis; machine learning; artificial intelligence
(This special issue belongs to the Section Molecular Informatics)
Cyclodextrins: Properties and Applications, 2nd Edition submission deadline 20 Sep 2024 | 4 articles | Viewed by 2769 | Submission Open
Keywords: cyclodextrins; controlled release systems; structure modification; thermodynamic properties; transport properties
(This special issue belongs to the Section Macromolecules)
Targeted Therapy for Immune Diseases
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 2744 | Submission Open
Keywords: targeted therapy; immune diseases; biologics; immunotherapy; precision medicine; nanoparticles; biomarkers
(This special issue belongs to the Section Molecular Immunology)
From Molecular Insights to Novel Therapies: Neurological Diseases
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 2743 | Submission Open
Keywords: neurological diseases; neurodegenerative diseases; epilepsy; mental illness; transgenic animal models; molecular pathways; metabolism disabilities; mitochondrial dysfunction; oxidative stress; disturbances in epigenetic regulation
(This special issue belongs to the Section Molecular Neurobiology)
Applications of Mesenchymal Stem Cells in Neuroscience 2.0 submission deadline 20 Sep 2024 | 1 articles | Viewed by 2692 | Submission Open
Keywords: mesenchymal stem cells; extracellular vesicles; microvesicles; exosomes; neurodegenerative diseases; neurological conditions  ; inflammation  ; cell therapy
(This special issue belongs to the Section Molecular Neurobiology)
Gastrointestinal: Inflammation, Immunity and Cancer Pathways
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 2643 | Submission Open
Keywords: inflammation and cancer biology; infectious agents; post-translational modification; signaling pathway; apoptosis; autophagy; necrosis; necroptosis; innate immunity; host– pathogens interactions; cell proliferation; tumor microenvironment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Diagnostic Tools and Biomarkers in Oncological Diseases 2.0
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 2523 | Submission Open
Keywords: oncologic diseases; biomarkers; liquid biopsy; miRNA; ncRNA; exosomes
(This special issue belongs to the Section Molecular Oncology)
Traumatic Brain Injury/Chronic Traumatic Encephalopathy as Cause of Alzheimer’s Disease: Physics and Molecular Biology in the Genesis of Neurodegeneration?
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 2456 | Submission Open
Keywords: traumatic brain injury (TBI); chronic traumatic encephalopathy (CTE); head impacts; Alzheimer's disease (AD); neurodegeneration
(This special issue belongs to the Section Molecular Neurobiology)
Nucleic Acid-Based Diagnostics for Infectious Diseases
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 2436 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Pregnancy Complications submission deadline 20 Sep 2024 | 3 articles | Viewed by 2403 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Polymeric Materials for Biomedical Applications, Drug and Gene Delivery
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 2367 | Submission Open
Keywords: biodegradable polymers; polyesters; scaffolds; tissue engineering; drug delivery; gene delivery; functional materials; biomedical application
(This special issue belongs to the Section Macromolecules)
Immunotherapy in Cancer: Molecular Basis and Novel Therapeutic Approaches
edited by Yonggu Lee
submission deadline 20 Sep 2024 | 2 articles | Viewed by 2313 | Submission Open
Keywords: cellular immunotherapy; adoptive immunotherapy; chimeric antigen receptor T-cell; epigenetic modulation; immunometabolism; microbiome; immune checkpoint inhibitor; cancer vaccine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Insights into Anti-cancer Drug Discovery and Development
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 2232 | Submission Open
Keywords: anti-cancer drug resistant; cancer recurrence; cancer metastasis; cancer stem cells; target validation; target identification; metabolic reprogramming of cancer stem cells; unmet medical needs
(This special issue belongs to the Section Molecular Pharmacology)
Precision Mеdicinе Mееts 3D Printing: Molecular Approachеs to Pеrsonalizеd Implants and Mеdical Dеvicеs
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 2178 | Submission Open
(This special issue belongs to the Section Macromolecules)
Gap Junction Channels and Hemichannels in Health and Disease 2.0 submission deadline 20 Sep 2024 | 2 articles | Viewed by 2150 | Submission Open
Keywords: gap junction channel; hemichannel; CaM; calmodulin
(This special issue belongs to the Section Biochemistry)
Advances in the Pathogenesis of Diabetic Kidney Disease: Second Edition submission deadline 20 Sep 2024 | 2 articles | Viewed by 2142 | Submission Open
Keywords: diabetic kidney disease; diagnosis; pathogenesis; treatment; molecular mechanisms; chronic kidney disease; end-stage renal disease; inflammation; oxidative stress; glycemia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Glioblastoma: Bridging Genetics, Epigenetics, Immunology and Pathophysiology to Advanced Therapies
edited by Felix Mircea Brehar and Alexandru Vladimir Ciurea
submission deadline 20 Sep 2024 | 1 articles | Viewed by 2061 | Submission Open
Keywords: glioblastoma (GBM); therapeutic resistance; immunological responses; biomarkers; genetic mutations; epigenetic modifications; pathophysiological conditions; tumor microenvironment; drug delivery; targeted therapies
(This special issue belongs to the Section Molecular Oncology)
Inflammatory Bowel Disease: Molecular Insights
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 2011 | Submission Open
Keywords: genomic sequencing; microbiome; dysbiosis; commensal flora; omics; immunobiology; colitis; Crohn’ s disease; ulcerative colitis; multiomics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Modeling Lipid Membranes and Permeation: Exploring Structure, Dynamics, and Transport Phenomena submission deadline 20 Sep 2024 | 2 articles | Viewed by 2007 | Submission Open
Keywords: lipid membranes; molecular dynamics simulations; lipid bilayers; permeation mechanisms across lipid membrane; biophysics; drug discovery; nanotechnology; permeation phenomena
(This special issue belongs to the Section Biochemistry)
Precision Medicine for Oral Diseases and Cancers
edited by Marina Di Domenico and
submission deadline 20 Sep 2024 | 2 articles | Viewed by 1968 | Submission Open
Keywords: cancer; laboratory medicine; personalized medicine; diagnostic; machine learning; precision medicine; stem cells; oral diseases; clinical biochemistry; translational medicine; geometry optimization of biomaterials; cell adhesion; computational mechanobiology; bioengineering; bioscaffolds; systemic diseases; general health; quality of life; microbiota
(This special issue belongs to the Section Molecular Pharmacology)
Calcium Homeostasis of Cells in Health and Disease 2.0 submission deadline 20 Sep 2024 | 2 articles | Viewed by 1949 | Submission Open
Keywords: Ca2+; calcium homeostasis; calcium-binding proteins; aging; disease
(This special issue belongs to the Section Biochemistry)
Molecular Research and Treatment of Breast Cancer 3.0
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 1925 | Submission Open
Keywords: biomarkers; breast cancer; cancer stem cells; cell signaling; circulating tumor cells; drug discovery; molecular diagnostics; molecular profiling; targeted therapy; therapy resistance
(This special issue belongs to the Section Molecular Oncology)
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