Systemic Sclerosis: New Insight into Pathogenesis, Molecular and Immune Mechanisms
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 April 2025) | Viewed by 829
Special Issue Editor
Interests: heart failure; rheumatoid arthritis; tumor necrosis factor; TNF inhibitors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Systemic sclerosis, a connective tissue disease that lies at the intersection of autoimmunity and extensive fibrotic processes, is attracting increasing attention from researchers. Despite the significant progress achieved in our understanding of the mechanisms underlying autoimmunity, inflammation, and fibrosis, many pathophysiological aspects of this disease remain unresolved. This Special Issue will provide a platform for sharing the latest advances in the pathophysiology, treatment, and clinical manifestations of systemic sclerosis. Special emphasis will be placed on the molecules involved in profibrotic signaling, disease biomarkers, and genetic markers. We also welcome clinical studies providing up-to-date insights into patient characteristics, as well as the impact of comorbidities on the development and progression of the disease. Clinical and laboratory studies, as well as review papers, are encouraged.
Prof. Dr. Przemysław Kotyla
Guest Editor
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Keywords
- systemic sclerosis
- autoimmunity
- inflammation
- fibrosis
- pathophysiology and treatment
- profibrotic signaling
- biomarkers
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