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Phytochemicals of Natural Products: Source, Analysis, and Bioactivities

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 787

Special Issue Editors


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Guest Editor
Department of Food Science, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan
Interests: food nutrition and health; functional food; food analysis; biochemistry

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Guest Editor
Department of Biological Science and Technology, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan
Interests: bioactive compound purification technology and chemical structure identification; natural product chemistry; organic spectroscopy

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Guest Editor
Institute of Biomedical Science, National Chung-Hsing University, Taichung 402, Taiwan
Interests: tumor immunology; autoimmunology; bioactivities of natural products; organic chemistry of synthetic drugs

Special Issue Information

Dear Colleagues,

Phytochemicals, the diverse chemical compounds derived from natural products. They exhibit a wide range of bioactivities, playing crucial roles in human health, pharmaceuticals, and agriculture.

We are delighted to announce the launch of a Special Issue in IJMS, titled "Phytochemicals of Natural Products: Source, Analysis, and Bioactivities". This Special Issue aims to foster interdisciplinary collaboration and accelerate the translation of phytochemical research into practical applications.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • The isolation, identification, and characterization of phytochemicals;
  • Innovative analytical techniques for phytochemical detection and quantification;
  • Exploration of phytochemical bioactivities, such as antioxidant, antimicrobial, anticancer, antiobesity, and other properties;
  • Studies on the mechanisms of action of phytochemicals.

Prof. Dr. Yu-Kuo Chen
Prof. Dr. Chi-I Chang
Prof. Dr. Chi-Chien Lin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • phytochemicals
  • bioactive compounds
  • natural products
  • bioactivities
  • purification
  • chemoprevention
  • chemotherapy

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Published Papers (1 paper)

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Research

15 pages, 3066 KiB  
Article
Flower Color and Seed Coat Color as a Phenotypic Marker: Correlations with Fatty Acid Composition, Antioxidant Properties, and Metabolite Profiles in Safflower (Carthamus tinctorius L.)
by Weilan Li, Eun-Gyeong Kim, Dongho Lee, Young-Min Choi, Jae-Eun Lee, Sookyeong Lee, Gi-An Lee and Eunae Yoo
Int. J. Mol. Sci. 2025, 26(7), 3105; https://doi.org/10.3390/ijms26073105 - 27 Mar 2025
Viewed by 361
Abstract
Safflower (Carthamus tinctorius L.) is a versatile oilseed crop valued for its adaptability, high oil quality, and antioxidant properties. This study investigates the influence of flower color (FC) on the phenotypic diversity of 172 safflower accessions, analyzing agronomic traits, metabolite profiles, and [...] Read more.
Safflower (Carthamus tinctorius L.) is a versatile oilseed crop valued for its adaptability, high oil quality, and antioxidant properties. This study investigates the influence of flower color (FC) on the phenotypic diversity of 172 safflower accessions, analyzing agronomic traits, metabolite profiles, and antioxidant capacities. Frequency distribution, effect size, principal component analysis (PCA), and network analysis were employed to elucidate trait associations and interrelationships. FC significantly impacted traits such as oleic acid (OA), linoleic acid (LA), oleic desaturation ratio (ODR), and N-feruloylserotonin (FS), with large effect sizes (η2 > 0.16). Medium effects were observed for 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) scavenging capacity, palmitic acid (PA), and flowering date (FD). PCA and network analyses highlighted relationships between FC and other fatty acid and antioxidant traits. Qualitative traits such as seed coat color (SCC) and thorn of involucre (TI) also showed significant associations with FC, underscoring its role as a phenotypic marker. These findings provide a robust framework for trait-based breeding strategies in safflower and emphasize the need for further genetic validation of these associations. Full article
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