Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
8.1
4.9
Journals
IJMS
Special Issues
Advances in Secondary Metabolites in Plants
ijms-logo
Submit to Special Issue Submit Abstract to Special Issue Review for IJMS Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Advances in Secondary Metabolites in Plants

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 1039

Special Issue Editor

Prof. Dr. Sławomir Dresler

E-Mail Website
Guest Editor
1. Department of Analytical Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland
2. Department of Plant Physiology and Biophysics, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland
Interests: phytochemistry; pharmacognosy; plant–environment interactions; elicitation of secondary metabolites; chemoinformatics in phytochemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue, entitled “Advances in Secondary Metabolites in Plants”, focuses on the diverse and significant roles of plant secondary metabolites. With over 200,000 known compounds, these metabolites are integral to the survival, adaptation, and evolution of plants and have immense ecological, medicinal, and pharmaceutical value. This Special Issue will explore the biosynthesis, biochemical mechanisms, and biological activities of these compounds, shedding light on their roles in plant communication, stress resistance, and mutualistic relationships. We invite submissions on the pharmacological potential of secondary metabolites, their therapeutic applications, and biotechnology approaches to their production and modification. This Special Issue aims to provide a comprehensive overview of current advances, highlighting the significance of secondary metabolites for both plant science and human health.

Prof. Dr. Sławomir Dresler
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • specialized metabolites
  • biosynthesis pathways
  • pharmacological applications
  • medicinal plants
  • plant stress resistance
  • abiotic and biotic elicitors
  • chemometric analysis
  • plant biotechnology
  • therapeutic potential
  • plant signaling and communication

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

16 pages, 9327 KiB  
Article
Capillary Electrophoresis Optimization for Metabolite Separation in Hypogymnia physodes Using DoE: Validation Across Lichen Species
by Sławomir Dresler, Aneta Hałka-Grysińska, Izabela Baczewska, Hanna Wójciak, Barbara Hawrylak-Nowak, Jozef Kováčik, Olha Mykhailenko, Christian Zidorn, Joanna Sagan and Agnieszka Hanaka
Int. J. Mol. Sci. 2025, 26(10), 4828; https://doi.org/10.3390/ijms26104828 - 18 May 2025
Viewed by 174
Abstract
Lichen-specific natural products exhibit a wide range of biological activities, which makes them potentially useful in the pharmaceutical, cosmetic, and nutritional industries. In the present study, a capillary electrophoresis method was developed and optimized for the separation of seven major metabolites, physodic acid, [...] Read more.
Lichen-specific natural products exhibit a wide range of biological activities, which makes them potentially useful in the pharmaceutical, cosmetic, and nutritional industries. In the present study, a capillary electrophoresis method was developed and optimized for the separation of seven major metabolites, physodic acid, 3-hydroxyphysodic acid, atranorin, physodalic acid, chloroatranorin, salazinic acid, and protocetraric acid, found in Hypogymnia physodes. The optimization was performed using a design of experiments approach, focusing on four critical parameters: boric acid concentration, deoxycholic acid concentration, methanol content, and buffer pH. The overall separation efficiency was used as the response factor for optimization. The optimal separation conditions were achieved using a buffer composed of 60 mM boric acid, 70 mM deoxycholic acid, and 14% methanol at pH 9.6. The validated method was subsequently applied for the chemophenetic analysis of 28 lichen species belonging to the families Cladoniaceae, Parmeliaceae, Physciaceae, Ramalinaceae, and Teloschistaceae. In addition to the above-mentioned lichen compounds, the lichens examined showed the presence of evernic acid, usnic acid, and physicon. The developed CE method offers a reliable and efficient tool for the characterization of lichen metabolites, with potential applications in both botany and natural product research. Full article
(This article belongs to the Special Issue Advances in Secondary Metabolites in Plants)
►▼ Show Figures

Figure 1

16 pages, 4329 KiB  
Article
The Enhancement of Biomass Accumulation, Caffeoylquinic Acid Derivative Production, and Antioxidant Activity of Rhaponticum carthamoides Transformed Roots Cultured in a Nutrient Sprinkle Bioreactor
by Ewa Skała, Monika A. Olszewska and Agnieszka Kicel
Int. J. Mol. Sci. 2025, 26(4), 1422; https://doi.org/10.3390/ijms26041422 - 8 Feb 2025
Viewed by 612
Abstract
Rhaponticum carthamoides (Willd.) Iljin. is an endemic plant species found in Siberia, Mongolia, and Kazakhstan. Its roots and rhizomes are used to treat physical fatigue and weakness following illness. The present study examines the scaling up of caffeoylquinic acid (CQA) derivative and flavonoid [...] Read more.
Rhaponticum carthamoides (Willd.) Iljin. is an endemic plant species found in Siberia, Mongolia, and Kazakhstan. Its roots and rhizomes are used to treat physical fatigue and weakness following illness. The present study examines the scaling up of caffeoylquinic acid (CQA) derivative and flavonoid production in R. carthamoides transformed roots. The transformed roots were grown in shaken Erlenmeyer flasks of varying volumes (0.5–2 L), a temporary immersion system (TIS) (Rita® and PlantForm bioreactors), and a nutrient sprinkle bioreactor (NSB) in Woody Plant medium for 35 days. The highest dry biomass production was achieved in the 0.5 L and 1 L flasks and in the NSB bioreactor, yielding 22.2 to 20.4 g/L—approximately 14 to 23 times the weight of the inoculum. The accumulation of individual specialized metabolites varied depending on the culture system used. The peak amount of CQAs (544.5 mg/L), in terms of the increase in dry weight and metabolite levels, was obtained in the NSB bioreactor. The primary CQAs were chlorogenic acid (5-CQA) and a tri-CQA 1. The highest concentration of 5-CQA (7.38 mg/g DW) was found in the roots cultivated in the NSB bioreactor. In contrast, the tri-CQA 1 dominated in the roots from 2 L shaken Erlenmeyer flasks (8.44 mg/g DW). Our findings demonstrate that transformed roots growing in an NSB bioreactor are an effective system for increasing CQA production, potentially serving as an alternative source. This biotechnological approach could help reduce the overexploitation of field-grown R. carthamoides, a currently threatened species. Full article
(This article belongs to the Special Issue Advances in Secondary Metabolites in Plants)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop